Danio rerio

0 known processes

LOC100534776

toll-like receptor 7-like

LOC100534776 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.150
regulation of production of molecular mediator of immune response GO:0002700 1 0.125
multicellular organismal metabolic process GO:0044236 2 0.106
positive regulation of immune effector process GO:0002699 3 0.094
larval development GO:0002164 2 0.090
dicarboxylic acid transport GO:0006835 1 0.075
positive regulation of cytokine production GO:0001819 2 0.074
production of molecular mediator of immune response GO:0002440 2 0.073
regulation of biological quality GO:0065008 263 0.073
cellular response to lipopolysaccharide GO:0071222 3 0.071
cellular response to external stimulus GO:0071496 2 0.068
neuron differentiation GO:0030182 353 0.063
toll like receptor signaling pathway GO:0002224 4 0.062
interferon beta production GO:0032608 1 0.062
immune system process GO:0002376 241 0.060
regulation of response to stimulus GO:0048583 269 0.059
response to abiotic stimulus GO:0009628 122 0.059
type i interferon production GO:0032606 2 0.056
homeostatic process GO:0042592 142 0.054
cell surface receptor signaling pathway GO:0007166 325 0.054
immunoglobulin mediated immune response GO:0016064 3 0.054
response to ketone GO:1901654 1 0.052
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.051
single organism localization GO:1902578 225 0.051
collagen metabolic process GO:0032963 2 0.050
signal transduction GO:0007165 455 0.049
aromatic compound biosynthetic process GO:0019438 217 0.049
establishment of localization GO:0051234 244 0.048
regulation of establishment of protein localization GO:0070201 4 0.048
regulation of protein transport GO:0051223 3 0.048
cellular component morphogenesis GO:0032989 336 0.047
chloride transmembrane transport GO:1902476 4 0.046
determination of bilateral symmetry GO:0009855 204 0.046
single fertilization GO:0007338 3 0.045
organic cyclic compound metabolic process GO:1901360 301 0.045
cellular biosynthetic process GO:0044249 286 0.045
response to stress GO:0006950 263 0.044
regulation of interferon beta production GO:0032648 1 0.042
vasculature development GO:0001944 278 0.042
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.041
immune effector process GO:0002252 23 0.041
transport GO:0006810 220 0.041
heterocycle biosynthetic process GO:0018130 215 0.041
death GO:0016265 121 0.040
rna biosynthetic process GO:0032774 181 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
response to external stimulus GO:0009605 264 0.040
regulation of innate immune response GO:0045088 11 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
multicellular organismal macromolecule metabolic process GO:0044259 2 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.039
regulation of protein targeting GO:1903533 2 0.039
nuclear transport GO:0051169 4 0.038
antimicrobial humoral response GO:0019730 2 0.038
regulation of type i interferon production GO:0032479 2 0.038
regulation of reactive oxygen species metabolic process GO:2000377 2 0.037
reactive oxygen species biosynthetic process GO:1903409 1 0.037
positive regulation of transport GO:0051050 2 0.037
cellular component biogenesis GO:0044085 178 0.037
determination of left right symmetry GO:0007368 179 0.037
protein secretion GO:0009306 1 0.035
rna metabolic process GO:0016070 219 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
b cell mediated immunity GO:0019724 3 0.033
cell morphogenesis GO:0000902 289 0.033
nitric oxide biosynthetic process GO:0006809 2 0.033
cellular amine metabolic process GO:0044106 2 0.032
regulation of nucleocytoplasmic transport GO:0046822 2 0.032
response to alkaloid GO:0043279 2 0.032
nucleocytoplasmic transport GO:0006913 4 0.032
cell part morphogenesis GO:0032990 246 0.032
single organism transport GO:0044765 206 0.032
cellular response to biotic stimulus GO:0071216 3 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.031
defense response to other organism GO:0098542 33 0.031
taxis GO:0042330 109 0.031
i kappab kinase nf kappab signaling GO:0007249 4 0.031
cellular component assembly GO:0022607 170 0.031
cognition GO:0050890 1 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
regulation of cytoplasmic transport GO:1903649 4 0.030
response to chemical GO:0042221 320 0.030
regulation of developmental process GO:0050793 247 0.030
protein localization to nucleus GO:0034504 3 0.030
positive regulation of biological process GO:0048518 253 0.030
aging GO:0007568 2 0.030
tube morphogenesis GO:0035239 349 0.029
positive regulation of type i interferon production GO:0032481 1 0.028
regulation of protein localization to nucleus GO:1900180 2 0.028
positive regulation of innate immune response GO:0045089 8 0.028
b cell activation GO:0042113 2 0.028
negative regulation of cellular process GO:0048523 283 0.028
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.028
regulation of binding GO:0051098 3 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.028
biosynthetic process GO:0009058 294 0.028
locomotion GO:0040011 313 0.027
amine metabolic process GO:0009308 2 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
heterocycle metabolic process GO:0046483 290 0.027
peptide transport GO:0015833 1 0.027
establishment of protein localization to organelle GO:0072594 4 0.026
response to other organism GO:0051707 97 0.026
response to amine GO:0014075 1 0.026
single organism nuclear import GO:1902593 3 0.026
regulation of transcription dna templated GO:0006355 213 0.026
protein import GO:0017038 3 0.026
cellular ketone metabolic process GO:0042180 11 0.026
regulation of cellular metabolic process GO:0031323 320 0.025
protein targeting to nucleus GO:0044744 3 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
defense response GO:0006952 47 0.025
regulation of cytokine biosynthetic process GO:0042035 1 0.025
interferon beta biosynthetic process GO:0045350 1 0.025
lymphocyte proliferation GO:0046651 1 0.025
positive regulation of cell activation GO:0050867 1 0.025
mononuclear cell proliferation GO:0032943 1 0.025
cell projection organization GO:0030030 284 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
negative regulation of biological process GO:0048519 304 0.024
regulation of signal transduction GO:0009966 225 0.024
regulation of primary metabolic process GO:0080090 311 0.024
multicellular organism growth GO:0035264 4 0.024
single organism metabolic process GO:0044710 217 0.024
negative regulation of protein transport GO:0051224 3 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
multi organism process GO:0051704 134 0.024
response to glucocorticoid GO:0051384 1 0.024
monovalent inorganic cation transport GO:0015672 42 0.024
protein complex localization GO:0031503 1 0.024
positive regulation of immune response GO:0050778 11 0.024
regulation of cell activation GO:0050865 1 0.024
regulation of cell communication GO:0010646 232 0.024
protein acetylation GO:0006473 2 0.024
cellular component movement GO:0006928 335 0.023
response to glucose GO:0009749 3 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
positive regulation of stress activated mapk cascade GO:0032874 3 0.023
cytoskeleton dependent cytokinesis GO:0061640 3 0.023
sensory organ development GO:0007423 393 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
positive regulation of jnk cascade GO:0046330 3 0.023
regulation of biosynthetic process GO:0009889 250 0.023
lymphocyte mediated immunity GO:0002449 5 0.023
digestive tract morphogenesis GO:0048546 231 0.023
type i interferon biosynthetic process GO:0045351 1 0.023
positive regulation of cell cycle GO:0045787 3 0.022
head development GO:0060322 303 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
adult behavior GO:0030534 2 0.022
neuron development GO:0048666 262 0.022
blood vessel development GO:0001568 246 0.022
glucose homeostasis GO:0042593 1 0.022
digestive system development GO:0055123 289 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
nuclear import GO:0051170 3 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.021
apoptotic process GO:0006915 116 0.021
gene expression GO:0010467 252 0.021
neuron neuron synaptic transmission GO:0007270 1 0.021
brain development GO:0007420 293 0.021
organic substance biosynthetic process GO:1901576 289 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
maintenance of location GO:0051235 4 0.021
immune system development GO:0002520 191 0.021
cellular response to nutrient levels GO:0031669 2 0.021
fertilization GO:0009566 3 0.021
activation of innate immune response GO:0002218 6 0.021
wound healing GO:0042060 90 0.021
generation of neurons GO:0048699 385 0.021
response to external biotic stimulus GO:0043207 97 0.021
negative regulation of cytokine production GO:0001818 1 0.021
autophagy GO:0006914 4 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
exocytosis GO:0006887 1 0.020
eye development GO:0001654 277 0.020
regulation of reproductive process GO:2000241 4 0.020
programmed cell death GO:0012501 119 0.020
positive regulation of rna metabolic process GO:0051254 59 0.020
response to vitamin GO:0033273 3 0.020
morphogenesis of an epithelium GO:0002009 333 0.019
specification of symmetry GO:0009799 204 0.019
activation of immune response GO:0002253 9 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
positive regulation of dna metabolic process GO:0051054 1 0.019
meiotic nuclear division GO:0007126 4 0.019
immune response activating signal transduction GO:0002757 5 0.019
cation transmembrane transport GO:0098655 65 0.019
retina development in camera type eye GO:0060041 146 0.019
synaptic target recognition GO:0008039 1 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
cell projection morphogenesis GO:0048858 244 0.019
regulation of wound healing GO:0061041 2 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
response to drug GO:0042493 3 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
response to corticosteroid GO:0031960 1 0.019
heart development GO:0007507 313 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
response to virus GO:0009615 21 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
innate immune response activating signal transduction GO:0002758 5 0.018
regulation of cytokine production GO:0001817 3 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.018
leukocyte proliferation GO:0070661 1 0.018
carbohydrate homeostasis GO:0033500 1 0.018
angiogenesis GO:0001525 158 0.018
pattern recognition receptor signaling pathway GO:0002221 5 0.018
cellular amide metabolic process GO:0043603 4 0.018
transmembrane transport GO:0055085 120 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
protein acylation GO:0043543 3 0.018
meiotic cell cycle process GO:1903046 3 0.018
regulation of blood vessel size GO:0050880 2 0.018
erythrocyte homeostasis GO:0034101 55 0.018
protein import into nucleus GO:0006606 3 0.018
regulation of protein complex assembly GO:0043254 3 0.018
cellular protein catabolic process GO:0044257 4 0.017
startle response GO:0001964 4 0.017
somatic muscle development GO:0007525 4 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
cell death GO:0008219 121 0.017
oxoacid metabolic process GO:0043436 31 0.017
retina morphogenesis in camera type eye GO:0060042 79 0.017
anion transport GO:0006820 38 0.017
synaptic transmission cholinergic GO:0007271 4 0.017
regulation of gene expression GO:0010468 265 0.017
positive regulation of catabolic process GO:0009896 4 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
blood vessel morphogenesis GO:0048514 216 0.017
positive regulation of cellular process GO:0048522 201 0.017
embryonic organ development GO:0048568 381 0.017
stem cell maintenance GO:0019827 4 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
cellular localization GO:0051641 97 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
neurotransmitter secretion GO:0007269 2 0.016
protein heterooligomerization GO:0051291 1 0.016
hepaticobiliary system development GO:0061008 98 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
gtp metabolic process GO:0046039 4 0.016
reflex GO:0060004 2 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
regulation of metabolic process GO:0019222 359 0.016
peptide metabolic process GO:0006518 1 0.016
response to amphetamine GO:0001975 1 0.016
nucleic acid metabolic process GO:0090304 244 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.015
activation of mapk activity GO:0000187 3 0.015
cellular response to starvation GO:0009267 1 0.015
antibacterial humoral response GO:0019731 2 0.015
regulation of response to biotic stimulus GO:0002831 2 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
ion transmembrane transport GO:0034220 91 0.015
glucose import GO:0046323 2 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
response to amino acid GO:0043200 2 0.015
response to biotic stimulus GO:0009607 97 0.015
interspecies interaction between organisms GO:0044419 4 0.015
positive regulation of metabolic process GO:0009893 108 0.015
response to nutrient GO:0007584 3 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
chordate embryonic development GO:0043009 271 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
leukocyte mediated cytotoxicity GO:0001909 1 0.015
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
protein localization to plasma membrane GO:0072659 1 0.014
cell migration GO:0016477 237 0.014
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
gland development GO:0048732 143 0.014
rna localization GO:0006403 4 0.014
positive regulation of camp biosynthetic process GO:0030819 2 0.014
regulation of metal ion transport GO:0010959 4 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
nucleic acid templated transcription GO:0097659 181 0.014
g protein coupled receptor signaling pathway GO:0007186 74 0.014
homeostasis of number of cells GO:0048872 62 0.014
digestive tract development GO:0048565 265 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
response to acid chemical GO:0001101 17 0.014
positive regulation of wound healing GO:0090303 1 0.014
cell substrate adhesion GO:0031589 4 0.014
regulation of signaling GO:0023051 235 0.013
anion transmembrane transport GO:0098656 12 0.013
axonogenesis GO:0007409 152 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
cytokine metabolic process GO:0042107 1 0.013
peripheral nervous system neuron differentiation GO:0048934 28 0.013
defense response to bacterium GO:0042742 22 0.013
amino acid transport GO:0006865 2 0.013
regulation of circadian rhythm GO:0042752 4 0.013
response to hexose GO:0009746 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
chemotaxis GO:0006935 104 0.013
establishment of localization in cell GO:0051649 77 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
regulation of leukocyte mediated immunity GO:0002703 1 0.013
immune response regulating signaling pathway GO:0002764 5 0.013
regulation of blood pressure GO:0008217 1 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
immunoglobulin production GO:0002377 1 0.013
adaptive immune response GO:0002250 5 0.013
notochord development GO:0030903 54 0.013
regulation of immune effector process GO:0002697 5 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
response to monosaccharide GO:0034284 3 0.013
neurological system process GO:0050877 62 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
epithelial cell differentiation GO:0030855 116 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
nitric oxide metabolic process GO:0046209 2 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
regulation of protein catabolic process GO:0042176 1 0.012
chemical homeostasis GO:0048878 49 0.012
positive regulation of cell division GO:0051781 2 0.012
regulation of cell killing GO:0031341 2 0.012
growth GO:0040007 174 0.012
chloride transport GO:0006821 8 0.012
somitogenesis GO:0001756 87 0.012
muscle structure development GO:0061061 196 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
myeloid cell homeostasis GO:0002262 56 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
mitotic cytokinesis GO:0000281 3 0.012
response to organic cyclic compound GO:0014070 51 0.012
compound eye development GO:0048749 2 0.012
macromolecule localization GO:0033036 54 0.012
developmental growth GO:0048589 166 0.012
regulation of hormone secretion GO:0046883 2 0.012
mitochondrion organization GO:0007005 4 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
protein metabolic process GO:0019538 183 0.012
system process GO:0003008 185 0.012
striated muscle cell differentiation GO:0051146 129 0.012
regulation of inflammatory response GO:0050727 2 0.012
lipid storage GO:0019915 1 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.011
positive regulation of inflammatory response GO:0050729 1 0.011
regulation of calcium ion transport GO:0051924 2 0.011
response to bacterium GO:0009617 58 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
protein localization GO:0008104 40 0.011
amide biosynthetic process GO:0043604 1 0.011
phagocytosis GO:0006909 3 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
response to carbohydrate GO:0009743 3 0.011
neurotransmitter transport GO:0006836 2 0.011
negative regulation of kinase activity GO:0033673 4 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
regulation of programmed cell death GO:0043067 101 0.011
maintenance of gastrointestinal epithelium GO:0030277 7 0.011
inorganic anion transmembrane transport GO:0098661 10 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
inorganic anion transport GO:0015698 25 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
cation transport GO:0006812 81 0.011
regulation of natural killer cell mediated immunity GO:0002715 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
immune response GO:0006955 28 0.011
cellular protein metabolic process GO:0044267 129 0.011
organelle organization GO:0006996 227 0.011
hemopoiesis GO:0030097 183 0.011
positive regulation of cell killing GO:0031343 2 0.011
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of tube size GO:0035150 2 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
response to organic substance GO:0010033 153 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
neuron projection morphogenesis GO:0048812 161 0.011
skeletal muscle organ development GO:0060538 78 0.011
stem cell proliferation GO:0072089 4 0.011
regulation of body fluid levels GO:0050878 16 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.010
translational initiation GO:0006413 3 0.010
embryonic hemopoiesis GO:0035162 53 0.010
small molecule metabolic process GO:0044281 77 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
negative regulation of metabolic process GO:0009892 86 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
regulation of blood coagulation GO:0030193 1 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
regulation of dendrite development GO:0050773 3 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
regulation of multicellular organismal metabolic process GO:0044246 2 0.010
muscle cell differentiation GO:0042692 139 0.010
negative regulation of catabolic process GO:0009895 3 0.010
hindbrain development GO:0030902 91 0.010
hemostasis GO:0007599 13 0.010

LOC100534776 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.032
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
disease of metabolism DOID:0014667 0 0.022
eye disease DOID:5614 0 0.022
organ system cancer DOID:0050686 0 0.017
immune system disease DOID:2914 0 0.015
musculoskeletal system disease DOID:17 0 0.014
inherited metabolic disorder DOID:655 0 0.012