Danio rerio

0 known processes

LOC100004296

novel protein similar to murine T brachyury (T)

LOC100004296 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
specification of symmetry GO:0009799 204 0.217
larval development GO:0002164 2 0.149
establishment of localization GO:0051234 244 0.145
digestive system development GO:0055123 289 0.142
regionalization GO:0003002 274 0.134
digestive tract morphogenesis GO:0048546 231 0.129
determination of bilateral symmetry GO:0009855 204 0.120
tube morphogenesis GO:0035239 349 0.101
muscle structure development GO:0061061 196 0.092
gastrulation GO:0007369 208 0.091
cell migration involved in gastrulation GO:0042074 79 0.088
digestive tract development GO:0048565 265 0.081
heart morphogenesis GO:0003007 156 0.080
regulation of biological quality GO:0065008 263 0.077
determination of left right symmetry GO:0007368 179 0.076
protein localization to nucleus GO:0034504 3 0.073
negative regulation of cytoplasmic transport GO:1903650 2 0.072
embryonic organ development GO:0048568 381 0.071
locomotion GO:0040011 313 0.066
ameboidal type cell migration GO:0001667 143 0.066
regulation of synapse assembly GO:0051963 3 0.062
nucleobase containing compound metabolic process GO:0006139 274 0.062
regulation of signaling GO:0023051 235 0.061
regulation of reproductive process GO:2000241 4 0.061
cellular component biogenesis GO:0044085 178 0.061
central nervous system development GO:0007417 387 0.060
regulation of response to stimulus GO:0048583 269 0.059
heart development GO:0007507 313 0.059
determination of heart left right asymmetry GO:0061371 117 0.058
cellular component movement GO:0006928 335 0.057
signal transduction GO:0007165 455 0.057
cell motility GO:0048870 244 0.055
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.055
medial fin development GO:0033338 16 0.055
head development GO:0060322 303 0.055
response to chemical GO:0042221 320 0.054
kupffer s vesicle development GO:0070121 50 0.053
positive regulation of cellular process GO:0048522 201 0.053
protein metabolic process GO:0019538 183 0.052
axon development GO:0061564 166 0.052
cell surface receptor signaling pathway GO:0007166 325 0.051
embryo development ending in birth or egg hatching GO:0009792 271 0.051
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
positive regulation of biological process GO:0048518 253 0.050
organelle organization GO:0006996 227 0.050
release of sequestered calcium ion into cytosol GO:0051209 3 0.050
brain development GO:0007420 293 0.048
protein targeting to nucleus GO:0044744 3 0.047
regulation of signal transduction GO:0009966 225 0.047
nucleic acid templated transcription GO:0097659 181 0.047
regulation of cell communication GO:0010646 232 0.046
muscle cell differentiation GO:0042692 139 0.045
immune system process GO:0002376 241 0.044
transport GO:0006810 220 0.044
neuron differentiation GO:0030182 353 0.044
negative regulation of response to stimulus GO:0048585 104 0.044
regulation of protein import into nucleus GO:0042306 2 0.043
cellular component assembly GO:0022607 170 0.043
heterocycle metabolic process GO:0046483 290 0.043
regulation of metabolic process GO:0019222 359 0.043
localization of cell GO:0051674 244 0.043
nuclear transport GO:0051169 4 0.042
regulation of stem cell differentiation GO:2000736 4 0.042
regulation of sequestering of calcium ion GO:0051282 4 0.042
regulation of metal ion transport GO:0010959 4 0.042
neuron development GO:0048666 262 0.041
cellular macromolecule metabolic process GO:0044260 391 0.041
positive regulation of reproductive process GO:2000243 2 0.041
protein import GO:0017038 3 0.040
organonitrogen compound metabolic process GO:1901564 74 0.040
cell projection organization GO:0030030 284 0.040
maintenance of location GO:0051235 4 0.040
skeletal system development GO:0001501 181 0.040
positive regulation of cell adhesion GO:0045785 1 0.040
cell projection morphogenesis GO:0048858 244 0.039
establishment of localization in cell GO:0051649 77 0.039
nuclear import GO:0051170 3 0.039
cell morphogenesis GO:0000902 289 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
single organism localization GO:1902578 225 0.038
regulation of neuron projection development GO:0010975 40 0.038
regulation of protein localization to nucleus GO:1900180 2 0.036
vasculature development GO:0001944 278 0.035
regulation of binding GO:0051098 3 0.035
regulation of cellular amino acid metabolic process GO:0006521 0 0.035
convergent extension GO:0060026 118 0.035
immune system development GO:0002520 191 0.035
morphogenesis of an epithelium GO:0002009 333 0.034
sequestering of calcium ion GO:0051208 3 0.033
cell part morphogenesis GO:0032990 246 0.033
regulation of multicellular organism growth GO:0040014 4 0.033
nucleocytoplasmic transport GO:0006913 4 0.033
generation of neurons GO:0048699 385 0.032
organelle localization GO:0051640 49 0.032
dorsal ventral pattern formation GO:0009953 125 0.032
aging GO:0007568 2 0.031
regulation of cellular metabolic process GO:0031323 320 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
organelle assembly GO:0070925 110 0.031
gland development GO:0048732 143 0.031
biosynthetic process GO:0009058 294 0.031
rna biosynthetic process GO:0032774 181 0.031
cellular biosynthetic process GO:0044249 286 0.031
regulation of protein targeting GO:1903533 2 0.030
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.030
convergent extension involved in gastrulation GO:0060027 71 0.030
negative regulation of cellular process GO:0048523 283 0.030
regulation of establishment of protein localization GO:0070201 4 0.030
macromolecule biosynthetic process GO:0009059 227 0.029
post embryonic organ development GO:0048569 4 0.029
regulation of synapse organization GO:0050807 3 0.029
regulation of locomotion GO:0040012 55 0.028
regulation of localization GO:0032879 104 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
regulation of nucleocytoplasmic transport GO:0046822 2 0.028
regulation of developmental process GO:0050793 247 0.027
regulation of rna metabolic process GO:0051252 224 0.027
neuron projection development GO:0031175 180 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
axonal defasciculation GO:0007414 2 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
multicellular organism growth GO:0035264 4 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
cellular response to endogenous stimulus GO:0071495 68 0.026
regulation of cellular response to growth factor stimulus GO:0090287 35 0.026
formation of primary germ layer GO:0001704 62 0.026
determination of ventral identity GO:0048264 21 0.026
negative regulation of intracellular transport GO:0032387 3 0.026
negative regulation of sequestering of calcium ion GO:0051283 4 0.026
neuroblast proliferation GO:0007405 2 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.025
phagocytosis GO:0006909 3 0.025
cell morphogenesis involved in differentiation GO:0000904 195 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.024
regulation of anatomical structure morphogenesis GO:0022603 130 0.024
heart looping GO:0001947 94 0.024
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.024
anatomical structure homeostasis GO:0060249 36 0.024
single organism nuclear import GO:1902593 3 0.024
ear development GO:0043583 127 0.024
regulation of cell differentiation GO:0045595 142 0.024
response to external stimulus GO:0009605 264 0.023
hormone secretion GO:0046879 2 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
renal system development GO:0072001 94 0.023
regulation of bone mineralization GO:0030500 2 0.023
regulation of cellular component movement GO:0051270 55 0.023
cellular ketone metabolic process GO:0042180 11 0.023
macromolecule modification GO:0043412 111 0.023
endoderm formation GO:0001706 29 0.023
single organism organelle organization GO:1902589 199 0.023
single organism cellular localization GO:1902580 46 0.023
positive regulation of transport GO:0051050 2 0.023
blood vessel development GO:0001568 246 0.022
regulation of cell morphogenesis GO:0022604 42 0.022
small molecule metabolic process GO:0044281 77 0.022
cell recognition GO:0008037 19 0.022
muscle cell development GO:0055001 115 0.022
hormone transport GO:0009914 2 0.022
cellular amine metabolic process GO:0044106 2 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
embryonic heart tube development GO:0035050 133 0.022
negative regulation of protein import into nucleus GO:0042308 2 0.022
sensory organ morphogenesis GO:0090596 200 0.021
stem cell proliferation GO:0072089 4 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
wnt signaling pathway GO:0016055 80 0.021
neuron projection morphogenesis GO:0048812 161 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
negative regulation of chemotaxis GO:0050922 4 0.021
signal transduction in absence of ligand GO:0038034 1 0.021
regulation of bmp signaling pathway GO:0030510 39 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
regulation of hormone secretion GO:0046883 2 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.021
cellular component morphogenesis GO:0032989 336 0.021
sequestering of metal ion GO:0051238 3 0.021
response to corticosteroid GO:0031960 1 0.021
protein import into nucleus GO:0006606 3 0.020
organic acid metabolic process GO:0006082 31 0.020
sensory perception of chemical stimulus GO:0007606 3 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
chemotaxis GO:0006935 104 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
rna metabolic process GO:0016070 219 0.020
gene expression GO:0010467 252 0.020
axon guidance GO:0007411 86 0.020
cellular component assembly involved in morphogenesis GO:0010927 107 0.020
homeostatic process GO:0042592 142 0.020
adherens junction organization GO:0034332 4 0.020
regulation of biosynthetic process GO:0009889 250 0.020
axonogenesis GO:0007409 152 0.019
neuron projection extension GO:1990138 45 0.019
wound healing GO:0042060 90 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
carboxylic acid catabolic process GO:0046395 3 0.019
oxoacid metabolic process GO:0043436 31 0.019
cytosolic calcium ion transport GO:0060401 3 0.019
establishment of organelle localization GO:0051656 45 0.019
cellular component disassembly GO:0022411 1 0.019
negative regulation of synapse assembly GO:0051964 2 0.019
negative regulation of signaling GO:0023057 96 0.018
compound eye development GO:0048749 2 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
embryonic hemopoiesis GO:0035162 53 0.018
eye development GO:0001654 277 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
negative regulation of cell communication GO:0010648 96 0.018
cartilage development GO:0051216 96 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
neuron recognition GO:0008038 18 0.018
anterior posterior pattern specification GO:0009952 152 0.018
cytoskeleton organization GO:0007010 96 0.018
regulation of cell activation GO:0050865 1 0.018
negative regulation of developmental process GO:0051093 65 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
alcohol biosynthetic process GO:0046165 2 0.017
single organism transport GO:0044765 206 0.017
peptide transport GO:0015833 1 0.017
regulation of histone deacetylation GO:0031063 2 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
autophagy GO:0006914 4 0.017
neuron projection guidance GO:0097485 86 0.017
ion homeostasis GO:0050801 41 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
cell cell signaling GO:0007267 52 0.017
response to endogenous stimulus GO:0009719 83 0.017
negative regulation of biological process GO:0048519 304 0.017
nephron epithelium morphogenesis GO:0072088 1 0.017
cellular localization GO:0051641 97 0.017
inner ear morphogenesis GO:0042472 63 0.017
hatching GO:0035188 4 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.016
blood vessel morphogenesis GO:0048514 216 0.016
phosphorylation GO:0016310 69 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
regulation of cell shape GO:0008360 1 0.016
peptidyl threonine modification GO:0018210 1 0.016
protein localization to plasma membrane GO:0072659 1 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
kidney development GO:0001822 92 0.016
taxis GO:0042330 109 0.016
negative regulation of catabolic process GO:0009895 3 0.016
calcium ion homeostasis GO:0055074 19 0.016
glucose import GO:0046323 2 0.016
single organism metabolic process GO:0044710 217 0.016
negative regulation of muscle tissue development GO:1901862 2 0.016
regulation of oocyte development GO:0060281 3 0.016
regulation of cell migration GO:0030334 40 0.016
striated muscle cell differentiation GO:0051146 129 0.015
actin cytoskeleton organization GO:0030036 63 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
cell cell recognition GO:0009988 1 0.015
regulation of protein transport GO:0051223 3 0.015
negative regulation of protein localization to nucleus GO:1900181 2 0.015
fin development GO:0033333 77 0.015
response to stress GO:0006950 263 0.015
microtubule based process GO:0007017 60 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
connective tissue development GO:0061448 99 0.015
negative regulation of striated muscle tissue development GO:0045843 2 0.015
organic substance biosynthetic process GO:1901576 289 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
growth GO:0040007 174 0.014
stem cell maintenance GO:0019827 4 0.014
cell adhesion mediated by integrin GO:0033627 1 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
notochord development GO:0030903 54 0.014
outflow tract morphogenesis GO:0003151 1 0.014
response to drug GO:0042493 3 0.014
regulation of neuron differentiation GO:0045664 56 0.014
response to fluid shear stress GO:0034405 2 0.014
embryonic skeletal joint development GO:0072498 3 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
axis specification GO:0009798 43 0.014
hard palate development GO:0060022 4 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
regulation of molecular function GO:0065009 70 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
striated muscle cell development GO:0055002 108 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
transmission of nerve impulse GO:0019226 19 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
regulation of cell development GO:0060284 100 0.013
positive regulation of cell activation GO:0050867 1 0.013
cellular protein modification process GO:0006464 100 0.013
developmental cell growth GO:0048588 52 0.013
regulation of biomineral tissue development GO:0070167 2 0.013
regulation of establishment of planar polarity GO:0090175 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
amine metabolic process GO:0009308 2 0.013
mesodermal cell migration GO:0008078 12 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
hemopoiesis GO:0030097 183 0.013
embryonic medial fin morphogenesis GO:0035122 6 0.013
negative regulation of axon guidance GO:1902668 1 0.013
inner ear development GO:0048839 126 0.013
mononuclear cell proliferation GO:0032943 1 0.013
response to growth factor GO:0070848 39 0.012
regulation of neurogenesis GO:0050767 87 0.012
negative regulation of protein transport GO:0051224 3 0.012
ear morphogenesis GO:0042471 64 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
type b pancreatic cell proliferation GO:0044342 1 0.012
protein heterooligomerization GO:0051291 1 0.012
regulation of primary metabolic process GO:0080090 311 0.012
transcription dna templated GO:0006351 181 0.012
anterior posterior axis specification GO:0009948 20 0.012
cellular protein metabolic process GO:0044267 129 0.012
cation transport GO:0006812 81 0.012
cardiocyte differentiation GO:0035051 44 0.012
medial fin morphogenesis GO:0035141 14 0.012
female sex differentiation GO:0046660 4 0.012
appendage morphogenesis GO:0035107 56 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of chondrocyte differentiation GO:0032330 1 0.012
neural tube development GO:0021915 62 0.012
specification of axis polarity GO:0065001 4 0.012
phagocytosis engulfment GO:0006911 1 0.012
cell projection assembly GO:0030031 64 0.012
somite development GO:0061053 96 0.011
cellular response to organic substance GO:0071310 105 0.011
metal ion homeostasis GO:0055065 26 0.011
primary neural tube formation GO:0014020 1 0.011
activation of mapk activity GO:0000187 3 0.011
organism emergence from protective structure GO:0071684 4 0.011
homeostasis of number of cells GO:0048872 62 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
angiogenesis GO:0001525 158 0.011
cell migration GO:0016477 237 0.011
synaptic vesicle localization GO:0097479 1 0.011
protein polymerization GO:0051258 4 0.011
somatic muscle development GO:0007525 4 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
nitric oxide metabolic process GO:0046209 2 0.011
embryonic digestive tract development GO:0048566 4 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
regulation of calcium ion transport GO:0051924 2 0.011
regulation of dendrite development GO:0050773 3 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
regulation of cell projection organization GO:0031344 44 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
cellular extravasation GO:0045123 1 0.011
regulation of autophagy GO:0010506 3 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
divalent inorganic cation transport GO:0072511 21 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
regulation of cell projection assembly GO:0060491 4 0.010
sensory perception of smell GO:0007608 2 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
negative regulation of leukocyte differentiation GO:1902106 1 0.010
negative chemotaxis GO:0050919 1 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
sensory organ development GO:0007423 393 0.010
cellular response to nutrient levels GO:0031669 2 0.010
positive regulation of synapse assembly GO:0051965 1 0.010
canonical wnt signaling pathway GO:0060070 48 0.010
liver development GO:0001889 96 0.010
regeneration GO:0031099 91 0.010
regulation of chromosome segregation GO:0051983 1 0.010
endodermal cell fate commitment GO:0001711 18 0.010
ion transmembrane transport GO:0034220 91 0.010
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.010
regulation of gene expression GO:0010468 265 0.010
endoderm development GO:0007492 49 0.010

LOC100004296 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.105
cardiovascular system disease DOID:1287 0 0.033
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
bone disease DOID:0080001 0 0.011