Danio rerio

0 known processes

fancf

Fanconi anemia, complementation group F

fancf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to chemical GO:0042221 320 0.058
cognition GO:0050890 1 0.058
response to transition metal nanoparticle GO:1990267 28 0.056
striated muscle tissue development GO:0014706 110 0.053
aging GO:0007568 2 0.053
regulation of metal ion transport GO:0010959 4 0.048
regulation of autophagy GO:0010506 3 0.046
zinc ion transport GO:0006829 2 0.043
maintenance of location GO:0051235 4 0.042
chordate embryonic development GO:0043009 271 0.041
generation of neurons GO:0048699 385 0.041
skeletal muscle fiber development GO:0048741 35 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.038
transmembrane transport GO:0055085 120 0.038
negative regulation of protein phosphorylation GO:0001933 4 0.038
skeletal muscle organ development GO:0060538 78 0.038
inorganic cation transmembrane transport GO:0098662 50 0.038
response to zinc ion GO:0010043 6 0.037
muscle cell development GO:0055001 115 0.037
morphogenesis of an epithelium GO:0002009 333 0.037
central nervous system development GO:0007417 387 0.036
transport GO:0006810 220 0.036
regulation of multicellular organism growth GO:0040014 4 0.035
vasculature development GO:0001944 278 0.034
regulation of metabolic process GO:0019222 359 0.034
autophagy GO:0006914 4 0.034
metal ion transport GO:0030001 58 0.034
multicellular organism growth GO:0035264 4 0.034
eye development GO:0001654 277 0.034
cation transmembrane transport GO:0098655 65 0.033
endosomal transport GO:0016197 2 0.033
positive regulation of transport GO:0051050 2 0.033
digestive tract morphogenesis GO:0048546 231 0.031
response to nutrient GO:0007584 3 0.031
skeletal muscle tissue development GO:0007519 67 0.031
regulation of cytoplasmic transport GO:1903649 4 0.030
cell substrate adhesion GO:0031589 4 0.030
digestive system development GO:0055123 289 0.030
tube morphogenesis GO:0035239 349 0.030
head development GO:0060322 303 0.030
single organism transport GO:0044765 206 0.030
zinc ion homeostasis GO:0055069 1 0.029
establishment of localization GO:0051234 244 0.029
zinc ion transmembrane transport GO:0071577 1 0.029
regulation of wound healing GO:0061041 2 0.029
nucleocytoplasmic transport GO:0006913 4 0.029
muscle tissue development GO:0060537 110 0.029
positive regulation of cell cycle GO:0045787 3 0.029
single organism localization GO:1902578 225 0.029
regulation of reproductive process GO:2000241 4 0.028
cation transport GO:0006812 81 0.028
cell migration GO:0016477 237 0.027
ion transport GO:0006811 114 0.027
angiogenesis GO:0001525 158 0.027
ion transmembrane transport GO:0034220 91 0.027
larval development GO:0002164 2 0.027
nuclear transport GO:0051169 4 0.026
blood vessel development GO:0001568 246 0.026
muscle organ development GO:0007517 101 0.026
muscle structure development GO:0061061 196 0.025
muscle fiber development GO:0048747 52 0.025
striated muscle cell development GO:0055002 108 0.025
meiotic nuclear division GO:0007126 4 0.025
sensory organ morphogenesis GO:0090596 200 0.025
adult behavior GO:0030534 2 0.024
myotube cell development GO:0014904 35 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
regulation of protein transport GO:0051223 3 0.024
regulation of response to stimulus GO:0048583 269 0.024
myotube differentiation GO:0014902 45 0.024
response to inorganic substance GO:0010035 38 0.024
response to stress GO:0006950 263 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
heterocycle metabolic process GO:0046483 290 0.024
lipid storage GO:0019915 1 0.023
sprouting angiogenesis GO:0002040 53 0.023
sensory organ development GO:0007423 393 0.023
cellular component movement GO:0006928 335 0.022
inorganic ion transmembrane transport GO:0098660 57 0.022
camera type eye development GO:0043010 222 0.022
stem cell maintenance GO:0019827 4 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
cellular response to extracellular stimulus GO:0031668 2 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
negative regulation of kinase activity GO:0033673 4 0.021
signal transduction GO:0007165 455 0.021
superoxide metabolic process GO:0006801 2 0.021
cellular component assembly GO:0022607 170 0.020
chemosensory behavior GO:0007635 1 0.020
embryonic organ development GO:0048568 381 0.020
brain development GO:0007420 293 0.020
regulation of mrna processing GO:0050684 3 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
cellular amine metabolic process GO:0044106 2 0.020
cellular response to reactive oxygen species GO:0034614 2 0.020
negative regulation of cellular process GO:0048523 283 0.019
negative regulation of biological process GO:0048519 304 0.019
nuclear export GO:0051168 1 0.019
cellular response to external stimulus GO:0071496 2 0.019
locomotion GO:0040011 313 0.019
female sex differentiation GO:0046660 4 0.019
gastrulation GO:0007369 208 0.019
regulation of signal transduction GO:0009966 225 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
striated muscle cell differentiation GO:0051146 129 0.019
retina morphogenesis in camera type eye GO:0060042 79 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
female gonad development GO:0008585 4 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
digestive tract development GO:0048565 265 0.018
hindbrain morphogenesis GO:0021575 22 0.018
regulation of biological quality GO:0065008 263 0.018
cortical cytoskeleton organization GO:0030865 1 0.018
protein metabolic process GO:0019538 183 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
positive regulation of catabolic process GO:0009896 4 0.018
phagocytosis GO:0006909 3 0.018
sequestering of metal ion GO:0051238 3 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
mechanosensory behavior GO:0007638 2 0.017
nucleic acid metabolic process GO:0090304 244 0.017
ovulation cycle GO:0042698 2 0.017
muscle cell differentiation GO:0042692 139 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
rna localization GO:0006403 4 0.017
cellular component biogenesis GO:0044085 178 0.017
mitochondrion organization GO:0007005 4 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
regulation of cell activation GO:0050865 1 0.017
determination of left right symmetry GO:0007368 179 0.017
cellular protein metabolic process GO:0044267 129 0.016
protein polymerization GO:0051258 4 0.016
blood vessel morphogenesis GO:0048514 216 0.016
glucose homeostasis GO:0042593 1 0.016
microtubule organizing center organization GO:0031023 1 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
response to metal ion GO:0010038 34 0.016
localization of cell GO:0051674 244 0.016
transition metal ion transport GO:0000041 6 0.016
cell motility GO:0048870 244 0.016
regulation of neurological system process GO:0031644 2 0.016
rna metabolic process GO:0016070 219 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
gtp catabolic process GO:0006184 2 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
cell matrix adhesion GO:0007160 4 0.016
regulation of transporter activity GO:0032409 2 0.015
transcription dna templated GO:0006351 181 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
heart development GO:0007507 313 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
regulation of cell communication GO:0010646 232 0.015
cellular transition metal ion homeostasis GO:0046916 3 0.015
homeostatic process GO:0042592 142 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
regulation of organelle assembly GO:1902115 4 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
ameboidal type cell migration GO:0001667 143 0.015
regulation of protein targeting GO:1903533 2 0.015
amine metabolic process GO:0009308 2 0.015
regulation of blood vessel size GO:0050880 2 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
protein import GO:0017038 3 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
positive regulation of cell activation GO:0050867 1 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
reactive oxygen species metabolic process GO:0072593 6 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
calcium ion import GO:0070509 4 0.015
cellular biosynthetic process GO:0044249 286 0.015
retina development in camera type eye GO:0060041 146 0.015
regulation of binding GO:0051098 3 0.014
single organism metabolic process GO:0044710 217 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
determination of bilateral symmetry GO:0009855 204 0.014
cellular ketone metabolic process GO:0042180 11 0.014
peptide transport GO:0015833 1 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
response to hexose GO:0009746 3 0.014
regulation of synapse organization GO:0050807 3 0.014
response to external stimulus GO:0009605 264 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
neuromast development GO:0048884 46 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
cell morphogenesis GO:0000902 289 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
mesoderm development GO:0007498 88 0.014
cellular protein catabolic process GO:0044257 4 0.014
nuclear import GO:0051170 3 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
cellular response to starvation GO:0009267 1 0.014
regulation of neurogenesis GO:0050767 87 0.014
regulation of signaling GO:0023051 235 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
lipid catabolic process GO:0016042 4 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
mesenchyme development GO:0060485 127 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
sensory system development GO:0048880 76 0.014
regulation of developmental process GO:0050793 247 0.013
b cell activation GO:0042113 2 0.013
somitogenesis GO:0001756 87 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
organic acid metabolic process GO:0006082 31 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
camera type eye morphogenesis GO:0048593 108 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of transmembrane transport GO:0034762 18 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
positive regulation of wound healing GO:0090303 1 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
cell projection organization GO:0030030 284 0.013
cellular response to nutrient levels GO:0031669 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
organic substance biosynthetic process GO:1901576 289 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
gtp metabolic process GO:0046039 4 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
neural retina development GO:0003407 49 0.013
immune system process GO:0002376 241 0.013
antimicrobial humoral response GO:0019730 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
phagosome maturation GO:0090382 1 0.012
convergent extension GO:0060026 118 0.012
regulation of endothelial cell proliferation GO:0001936 1 0.012
cytokinesis GO:0000910 3 0.012
somite development GO:0061053 96 0.012
notochord development GO:0030903 54 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
response to wounding GO:0009611 116 0.012
system process GO:0003008 185 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
vacuolar transport GO:0007034 2 0.012
membrane fusion GO:0061025 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
regulation of calcium ion transport GO:0051924 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
protein complex disassembly GO:0043241 1 0.012
translational initiation GO:0006413 3 0.012
response to abiotic stimulus GO:0009628 122 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of tube size GO:0035150 2 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
cellular component disassembly GO:0022411 1 0.012
calcium mediated signaling GO:0019722 2 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
protein dephosphorylation GO:0006470 3 0.012
cellular component morphogenesis GO:0032989 336 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
cell part morphogenesis GO:0032990 246 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
protein modification process GO:0036211 100 0.011
regulation of blood coagulation GO:0030193 1 0.011
response to ketone GO:1901654 1 0.011
single organism nuclear import GO:1902593 3 0.011
positive regulation of translation GO:0045727 1 0.011
regulation of translational initiation GO:0006446 1 0.011
regulation of synapse assembly GO:0051963 3 0.011
negative regulation of catabolic process GO:0009895 3 0.011
protein acetylation GO:0006473 2 0.011
b cell differentiation GO:0030183 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
lymphocyte proliferation GO:0046651 1 0.011
adherens junction organization GO:0034332 4 0.011
response to alkaloid GO:0043279 2 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
regulation of gtpase activity GO:0043087 2 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
organelle fusion GO:0048284 3 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
exocytosis GO:0006887 1 0.011
hormone transport GO:0009914 2 0.011
protein targeting to nucleus GO:0044744 3 0.011
lateral inhibition GO:0046331 1 0.011
lateral line system development GO:0048925 76 0.011
single organism membrane fusion GO:0044801 2 0.011
response to carbohydrate GO:0009743 3 0.011
regulation of dna templated transcription in response to stress GO:0043620 0 0.011
neuron differentiation GO:0030182 353 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
nucleic acid templated transcription GO:0097659 181 0.011
lateral line development GO:0048882 66 0.011
regionalization GO:0003002 274 0.011
organelle assembly GO:0070925 110 0.011
spermatid differentiation GO:0048515 2 0.011
peptidyl serine modification GO:0018209 2 0.011
lysosomal transport GO:0007041 2 0.011
specification of symmetry GO:0009799 204 0.011
post embryonic organ development GO:0048569 4 0.011
myeloid cell homeostasis GO:0002262 56 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
nitric oxide metabolic process GO:0046209 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
cell aging GO:0007569 2 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
regulation of primary metabolic process GO:0080090 311 0.010
regulation of nervous system development GO:0051960 90 0.010
protein acylation GO:0043543 3 0.010
negative regulation of gene expression GO:0010629 65 0.010
macromolecule modification GO:0043412 111 0.010
cell projection assembly GO:0030031 64 0.010
neurological system process GO:0050877 62 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
embryonic heart tube development GO:0035050 133 0.010
regulation of ion transmembrane transport GO:0034765 18 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
regulation of protein binding GO:0043393 3 0.010
regulation of macromolecule metabolic process GO:0060255 317 0.010
response to oxygen radical GO:0000305 2 0.010
secondary metabolic process GO:0019748 3 0.010
eye morphogenesis GO:0048592 144 0.010
convergent extension involved in gastrulation GO:0060027 71 0.010
protein stabilization GO:0050821 2 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
cilium organization GO:0044782 71 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
meiotic cell cycle process GO:1903046 3 0.010
anterior posterior pattern specification GO:0009952 152 0.010
energy reserve metabolic process GO:0006112 2 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
regulation of programmed cell death GO:0043067 101 0.010
biosynthetic process GO:0009058 294 0.010

fancf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.189
Human
disease of anatomical entity DOID:7 0 0.189
Human
bone marrow disease DOID:4961 0 0.189
Human
hematopoietic system disease DOID:74 0 0.189
Human
aplastic anemia DOID:12449 0 0.081
Human
anemia DOID:2355 0 0.081
Human
muscular disease DOID:0080000 0 0.024
musculoskeletal system disease DOID:17 0 0.024
congenital hypoplastic anemia DOID:1342 0 0.018
Human
fanconi s anemia DOID:13636 0 0.015
Human
myopathy DOID:423 0 0.014
muscle tissue disease DOID:66 0 0.014
nervous system disease DOID:863 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
cardiovascular system disease DOID:1287 0 0.011
disease of metabolism DOID:0014667 0 0.011
cancer DOID:162 0 0.011