Danio rerio

0 known processes

fancb

Fanconi anemia, complementation group B

fancb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.086
larval development GO:0002164 2 0.074
development of primary female sexual characteristics GO:0046545 4 0.053
cell substrate adhesion GO:0031589 4 0.053
stem cell maintenance GO:0019827 4 0.052
nucleobase containing compound biosynthetic process GO:0034654 205 0.049
cation transmembrane transport GO:0098655 65 0.048
digestive tract development GO:0048565 265 0.045
digestive tract morphogenesis GO:0048546 231 0.044
sprouting angiogenesis GO:0002040 53 0.043
female gonad development GO:0008585 4 0.040
muscle cell development GO:0055001 115 0.039
inorganic ion transmembrane transport GO:0098660 57 0.037
female sex differentiation GO:0046660 4 0.037
response to chemical GO:0042221 320 0.036
muscle cell differentiation GO:0042692 139 0.036
cellular response to reactive oxygen species GO:0034614 2 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.035
generation of neurons GO:0048699 385 0.033
eye development GO:0001654 277 0.033
nucleocytoplasmic transport GO:0006913 4 0.033
regulation of autophagy GO:0010506 3 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
response to oxygen radical GO:0000305 2 0.031
blood vessel development GO:0001568 246 0.031
myotube differentiation GO:0014902 45 0.031
transmembrane transport GO:0055085 120 0.031
cortical cytoskeleton organization GO:0030865 1 0.031
cell projection assembly GO:0030031 64 0.031
gastrulation GO:0007369 208 0.030
sequestering of metal ion GO:0051238 3 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
skeletal muscle fiber development GO:0048741 35 0.029
regulation of mrna processing GO:0050684 3 0.028
superoxide metabolic process GO:0006801 2 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
regulation of metal ion transport GO:0010959 4 0.028
sensory perception of chemical stimulus GO:0007606 3 0.027
cellular component assembly GO:0022607 170 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
cognition GO:0050890 1 0.026
maintenance of location GO:0051235 4 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of organelle assembly GO:1902115 4 0.025
positive regulation of transport GO:0051050 2 0.024
nuclear transport GO:0051169 4 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
ion transmembrane transport GO:0034220 91 0.024
regionalization GO:0003002 274 0.023
regulation of wound healing GO:0061041 2 0.023
nuclear export GO:0051168 1 0.023
germ line stem cell maintenance GO:0030718 2 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
zinc ion transport GO:0006829 2 0.022
determination of left right symmetry GO:0007368 179 0.022
regulation of ion transmembrane transporter activity GO:0032412 2 0.022
skeletal muscle organ development GO:0060538 78 0.022
striated muscle tissue development GO:0014706 110 0.022
digestive system development GO:0055123 289 0.022
aromatic compound biosynthetic process GO:0019438 217 0.021
cellular component movement GO:0006928 335 0.021
system process GO:0003008 185 0.021
negative regulation of metabolic process GO:0009892 86 0.021
response to inorganic substance GO:0010035 38 0.021
segmentation GO:0035282 97 0.021
chordate embryonic development GO:0043009 271 0.021
adult behavior GO:0030534 2 0.021
cellular component morphogenesis GO:0032989 336 0.020
cell matrix adhesion GO:0007160 4 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
regulation of cell activation GO:0050865 1 0.020
cellular amine metabolic process GO:0044106 2 0.020
vasculature development GO:0001944 278 0.020
organic substance biosynthetic process GO:1901576 289 0.020
reactive oxygen species metabolic process GO:0072593 6 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
transport GO:0006810 220 0.020
somite development GO:0061053 96 0.020
negative regulation of kinase activity GO:0033673 4 0.020
muscle organ development GO:0007517 101 0.020
negative regulation of biological process GO:0048519 304 0.020
inorganic cation transmembrane transport GO:0098662 50 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
neuron neuron synaptic transmission GO:0007270 1 0.019
regulation of blood vessel size GO:0050880 2 0.019
central nervous system development GO:0007417 387 0.019
regulation of biological quality GO:0065008 263 0.019
regulation of protein transport GO:0051223 3 0.019
ovulation cycle GO:0042698 2 0.019
protein stabilization GO:0050821 2 0.019
response to stress GO:0006950 263 0.019
skeletal muscle tissue development GO:0007519 67 0.019
striated muscle cell development GO:0055002 108 0.019
regulation of transmembrane transport GO:0034762 18 0.019
cellular response to dna damage stimulus GO:0006974 24 0.019
blood vessel morphogenesis GO:0048514 216 0.018
angiogenesis GO:0001525 158 0.018
regulation of transporter activity GO:0032409 2 0.018
response to superoxide GO:0000303 2 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
response to monosaccharide GO:0034284 3 0.018
cation transport GO:0006812 81 0.018
dna catabolic process GO:0006308 1 0.018
endosomal transport GO:0016197 2 0.018
cell morphogenesis GO:0000902 289 0.018
tube morphogenesis GO:0035239 349 0.018
regulation of signal transduction GO:0009966 225 0.018
autophagy GO:0006914 4 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
muscle structure development GO:0061061 196 0.017
negative regulation of mrna metabolic process GO:1903312 3 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
positive regulation of catabolic process GO:0009896 4 0.017
regulation of blood coagulation GO:0030193 1 0.017
cellular response to oxygen radical GO:0071450 2 0.017
amine metabolic process GO:0009308 2 0.017
regulation of cell communication GO:0010646 232 0.017
homeostatic process GO:0042592 142 0.017
glucose homeostasis GO:0042593 1 0.017
mitochondrion organization GO:0007005 4 0.017
post embryonic organ development GO:0048569 4 0.017
response to uv GO:0009411 3 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
response to abiotic stimulus GO:0009628 122 0.017
response to zinc ion GO:0010043 6 0.016
protein dephosphorylation GO:0006470 3 0.016
single organism localization GO:1902578 225 0.016
response to transition metal nanoparticle GO:1990267 28 0.016
b cell differentiation GO:0030183 1 0.016
organelle organization GO:0006996 227 0.016
myotube cell development GO:0014904 35 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
response to hexose GO:0009746 3 0.016
protein import GO:0017038 3 0.016
ameboidal type cell migration GO:0001667 143 0.016
hindbrain development GO:0030902 91 0.016
mechanosensory behavior GO:0007638 2 0.016
cell substrate junction assembly GO:0007044 2 0.016
myeloid cell homeostasis GO:0002262 56 0.016
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of rna metabolic process GO:0051252 224 0.015
response to amphetamine GO:0001975 1 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of blood pressure GO:0008217 1 0.015
camera type eye development GO:0043010 222 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
metal ion transport GO:0030001 58 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
regulation of reproductive process GO:2000241 4 0.015
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
lateral line development GO:0048882 66 0.015
establishment of localization GO:0051234 244 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
translational initiation GO:0006413 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
phagocytosis GO:0006909 3 0.015
protein localization to nucleus GO:0034504 3 0.015
cellular response to starvation GO:0009267 1 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
centrosome organization GO:0051297 1 0.015
sensory perception of smell GO:0007608 2 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of microtubule cytoskeleton organization GO:0070507 3 0.015
negative regulation of gene expression GO:0010629 65 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
nuclear import GO:0051170 3 0.014
chemosensory behavior GO:0007635 1 0.014
locomotion GO:0040011 313 0.014
ion transport GO:0006811 114 0.014
nitric oxide metabolic process GO:0046209 2 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
cellular response to external stimulus GO:0071496 2 0.014
regulation of calcium ion transport GO:0051924 2 0.014
spermatid differentiation GO:0048515 2 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of response to stimulus GO:0048583 269 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
response to external stimulus GO:0009605 264 0.014
morphogenesis of an epithelial sheet GO:0002011 49 0.014
regulation of transcription dna templated GO:0006355 213 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
monovalent inorganic cation transport GO:0015672 42 0.014
regulation of signaling GO:0023051 235 0.014
determination of bilateral symmetry GO:0009855 204 0.014
neuromast development GO:0048884 46 0.014
ovulation cycle process GO:0022602 2 0.013
lipid storage GO:0019915 1 0.013
b cell activation GO:0042113 2 0.013
localization of cell GO:0051674 244 0.013
nitrogen compound metabolic process GO:0006807 319 0.013
meiotic nuclear division GO:0007126 4 0.013
phagocytosis engulfment GO:0006911 1 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.013
muscle fiber development GO:0048747 52 0.013
response to glucose GO:0009749 3 0.013
cellular component biogenesis GO:0044085 178 0.013
regulation of localization GO:0032879 104 0.013
rna metabolic process GO:0016070 219 0.013
regulation of protein targeting GO:1903533 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
lens development in camera type eye GO:0002088 22 0.013
hemopoiesis GO:0030097 183 0.013
response to amine GO:0014075 1 0.013
cellular response to light stimulus GO:0071482 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
regulation of binding GO:0051098 3 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
rna localization GO:0006403 4 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
gtp metabolic process GO:0046039 4 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
gtp catabolic process GO:0006184 2 0.012
cellular protein metabolic process GO:0044267 129 0.012
larval heart development GO:0007508 2 0.012
signal transduction GO:0007165 455 0.012
positive regulation of cell cycle GO:0045787 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
vacuolar transport GO:0007034 2 0.012
negative regulation of developmental process GO:0051093 65 0.012
death GO:0016265 121 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
cellular localization GO:0051641 97 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.012
establishment of organelle localization GO:0051656 45 0.012
regulation of endothelial cell proliferation GO:0001936 1 0.012
protein metabolic process GO:0019538 183 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
single organism nuclear import GO:1902593 3 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
cell part morphogenesis GO:0032990 246 0.011
oxoacid metabolic process GO:0043436 31 0.011
cellular response to superoxide GO:0071451 2 0.011
calcium mediated signaling GO:0019722 2 0.011
protein acetylation GO:0006473 2 0.011
stem cell proliferation GO:0072089 4 0.011
cellular protein catabolic process GO:0044257 4 0.011
protein polymerization GO:0051258 4 0.011
protein acylation GO:0043543 3 0.011
sensory organ development GO:0007423 393 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
sensory organ morphogenesis GO:0090596 200 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
mitochondrial transport GO:0006839 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
cytoplasm organization GO:0007028 4 0.011
cellular amide metabolic process GO:0043603 4 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
lymphocyte proliferation GO:0046651 1 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
notochord development GO:0030903 54 0.011
specification of symmetry GO:0009799 204 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
striated muscle cell differentiation GO:0051146 129 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
retina development in camera type eye GO:0060041 146 0.010
cell projection organization GO:0030030 284 0.010
antimicrobial humoral response GO:0019730 2 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
peptide transport GO:0015833 1 0.010
lipid catabolic process GO:0016042 4 0.010
exocytosis GO:0006887 1 0.010
alpha amino acid metabolic process GO:1901605 3 0.010
lateral inhibition GO:0046331 1 0.010
heterocycle metabolic process GO:0046483 290 0.010
single organism metabolic process GO:0044710 217 0.010
hormone secretion GO:0046879 2 0.010
protein homooligomerization GO:0051260 3 0.010
organic cyclic compound metabolic process GO:1901360 301 0.010
secondary metabolic process GO:0019748 3 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
response to carbohydrate GO:0009743 3 0.010

fancb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.652
disease of anatomical entity DOID:7 0 0.652
bone marrow disease DOID:4961 0 0.652
hematopoietic system disease DOID:74 0 0.652
congenital hypoplastic anemia DOID:1342 0 0.393
aplastic anemia DOID:12449 0 0.393
fanconi s anemia DOID:13636 0 0.393
anemia DOID:2355 0 0.393
musculoskeletal system disease DOID:17 0 0.030
myopathy DOID:423 0 0.019
muscular disease DOID:0080000 0 0.019
muscle tissue disease DOID:66 0 0.019
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cardiovascular system disease DOID:1287 0 0.010