Danio rerio

0 known processes

psmc4

proteasome (prosome, macropain) 26S subunit, ATPase, 4

(Aliases: wu:fe38b10,zgc:63709)

psmc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.829
Yeast
cellular macromolecule metabolic process GO:0044260 391 0.702
Yeast
ubiquitin dependent protein catabolic process GO:0006511 3 0.595
Yeast
regulation of cellular metabolic process GO:0031323 320 0.555
Yeast
protein metabolic process GO:0019538 183 0.540
Yeast Fly
proteasomal protein catabolic process GO:0010498 2 0.515
modification dependent protein catabolic process GO:0019941 3 0.501
Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.499
Worm
cellular protein catabolic process GO:0044257 4 0.493
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.481
larval development GO:0002164 2 0.462
Worm
modification dependent macromolecule catabolic process GO:0043632 3 0.399
Yeast
proteolysis GO:0006508 38 0.280
Yeast Fly
nitrogen compound metabolic process GO:0006807 319 0.280
Yeast
regulation of macromolecule metabolic process GO:0060255 317 0.264
Yeast
dna templated transcription initiation GO:0006352 1 0.238
Yeast
regulation of protein complex assembly GO:0043254 3 0.232
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.229
Yeast
positive regulation of cellular process GO:0048522 201 0.227
Yeast
nucleobase containing compound metabolic process GO:0006139 274 0.194
Yeast
cellular component assembly GO:0022607 170 0.177
Yeast
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.175
Yeast
single fertilization GO:0007338 3 0.172
positive regulation of protein complex assembly GO:0031334 2 0.168
Yeast
aging GO:0007568 2 0.167
Worm
regulation of primary metabolic process GO:0080090 311 0.155
Yeast
nucleic acid metabolic process GO:0090304 244 0.149
Yeast
locomotion GO:0040011 313 0.147
spindle assembly involved in mitosis GO:0090307 1 0.146
positive regulation of biological process GO:0048518 253 0.141
Yeast
cellular macromolecule catabolic process GO:0044265 12 0.131
Yeast
rna metabolic process GO:0016070 219 0.127
Yeast
cellular nitrogen compound metabolic process GO:0034641 290 0.125
Yeast
positive regulation of metabolic process GO:0009893 108 0.120
Yeast
cellular biosynthetic process GO:0044249 286 0.117
Yeast
regulation of rna metabolic process GO:0051252 224 0.111
Yeast
regulation of gene expression GO:0010468 265 0.109
Yeast
macromolecule biosynthetic process GO:0009059 227 0.107
Yeast
cellular macromolecule biosynthetic process GO:0034645 224 0.106
Yeast
negative regulation of cellular process GO:0048523 283 0.103
cellular component biogenesis GO:0044085 178 0.100
Yeast
pronuclear migration GO:0035046 1 0.091
negative regulation of biological process GO:0048519 304 0.090
organic substance biosynthetic process GO:1901576 289 0.089
Yeast
regulation of biosynthetic process GO:0009889 250 0.086
Yeast
regulation of dna templated transcription elongation GO:0032784 3 0.085
protein n linked glycosylation GO:0006487 1 0.084
positive regulation of cellular component biogenesis GO:0044089 3 0.081
Yeast
heterocycle biosynthetic process GO:0018130 215 0.078
Yeast
regulation of endopeptidase activity GO:0052548 23 0.078
rrna catabolic process GO:0016075 1 0.075
cellular nitrogen compound biosynthetic process GO:0044271 218 0.074
Yeast
multicellular organism growth GO:0035264 4 0.073
cellular protein metabolic process GO:0044267 129 0.072
Yeast
fertilization GO:0009566 3 0.069
regulation of nucleoside metabolic process GO:0009118 2 0.067
heterocycle metabolic process GO:0046483 290 0.066
Yeast
regulation of metabolic process GO:0019222 359 0.062
Yeast
regulation of cellular biosynthetic process GO:0031326 245 0.062
Yeast
regulation of macromolecule biosynthetic process GO:0010556 225 0.061
Yeast
biosynthetic process GO:0009058 294 0.061
Yeast
regulation of peptidase activity GO:0052547 23 0.059
organic substance catabolic process GO:1901575 28 0.057
Yeast
response to external stimulus GO:0009605 264 0.055
reproduction GO:0000003 40 0.055
Worm
spindle assembly GO:0051225 2 0.055
autophagy GO:0006914 4 0.054
cell motility GO:0048870 244 0.054
regulation of transcription dna templated GO:0006355 213 0.054
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 4 0.054
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.054
regulation of protein ubiquitination GO:0031396 3 0.053
cellular aromatic compound metabolic process GO:0006725 295 0.053
Yeast
organic cyclic compound metabolic process GO:1901360 301 0.053
Yeast
response to stress GO:0006950 263 0.052
Fly
positive regulation of catabolic process GO:0009896 4 0.051
gene expression GO:0010467 252 0.049
Yeast
regionalization GO:0003002 274 0.049
phosphorus metabolic process GO:0006793 109 0.048
single organism organelle organization GO:1902589 199 0.048
positive regulation of cellular catabolic process GO:0031331 3 0.048
cellular response to extracellular stimulus GO:0031668 2 0.048
cellular response to stress GO:0033554 62 0.046
Fly
rna biosynthetic process GO:0032774 181 0.045
Yeast
atp catabolic process GO:0006200 4 0.045
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.044
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.043
programmed cell death GO:0012501 119 0.042
regulation of apoptotic process GO:0042981 98 0.041
maintenance of location GO:0051235 4 0.041
single organism metabolic process GO:0044710 217 0.041
regulation of signal transduction GO:0009966 225 0.039
protein polymerization GO:0051258 4 0.039
nucleoside monophosphate catabolic process GO:0009125 4 0.039
cellular response to external stimulus GO:0071496 2 0.038
macromolecule modification GO:0043412 111 0.038
regulation of multicellular organism growth GO:0040014 4 0.037
establishment of localization in cell GO:0051649 77 0.037
regulation of protein catabolic process GO:0042176 1 0.036
regulation of biological quality GO:0065008 263 0.035
response to organic substance GO:0010033 153 0.034
regulation of purine nucleotide catabolic process GO:0033121 2 0.034
gtp metabolic process GO:0046039 4 0.034
regulation of meiotic cell cycle GO:0051445 1 0.033
cellular localization GO:0051641 97 0.032
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.032
regulation of nucleic acid templated transcription GO:1903506 213 0.031
Yeast
mitotic cell cycle process GO:1903047 48 0.031
ncrna catabolic process GO:0034661 1 0.031
pole plasm assembly GO:0007315 4 0.031
signal transduction GO:0007165 455 0.031
death GO:0016265 121 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
Yeast
positive regulation of cell cycle GO:0045787 3 0.029
protein modification process GO:0036211 100 0.029
sister chromatid segregation GO:0000819 6 0.028
segmentation GO:0035282 97 0.028
meiotic nuclear division GO:0007126 4 0.028
phosphate containing compound metabolic process GO:0006796 108 0.028
positive regulation of cellular metabolic process GO:0031325 94 0.028
Yeast
protein complex assembly GO:0006461 30 0.028
Yeast
regulation of chromosome segregation GO:0051983 1 0.028
regulation of programmed cell death GO:0043067 101 0.028
small molecule metabolic process GO:0044281 77 0.028
chordate embryonic development GO:0043009 271 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.028
regulation of catalytic activity GO:0050790 55 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.028
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
Yeast
positive regulation of macromolecule metabolic process GO:0010604 93 0.027
Yeast
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
catabolic process GO:0009056 32 0.027
Yeast
organelle organization GO:0006996 227 0.027
head development GO:0060322 303 0.027
cellular response to chemical stimulus GO:0070887 157 0.026
regulation of gtpase activity GO:0043087 2 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
Yeast
macromolecular complex subunit organization GO:0043933 74 0.025
Yeast
single organism reproductive process GO:0044702 40 0.025
single organism localization GO:1902578 225 0.025
regulation of cell activation GO:0050865 1 0.025
regulation of hydrolase activity GO:0051336 28 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
ncrna metabolic process GO:0034660 12 0.024
nuclear migration GO:0007097 3 0.024
regulation of cellular protein metabolic process GO:0032268 52 0.024
mitotic sister chromatid segregation GO:0000070 6 0.023
cell death GO:0008219 121 0.023
regulation of proteolysis GO:0030162 24 0.023
meiotic cell cycle process GO:1903046 3 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
regulation of gtp catabolic process GO:0033124 2 0.023
apoptotic process GO:0006915 116 0.023
meiosis ii GO:0007135 1 0.023
ribose phosphate metabolic process GO:0019693 27 0.023
positive regulation of proteolysis GO:0045862 10 0.023
regulation of protein metabolic process GO:0051246 56 0.023
guanosine containing compound catabolic process GO:1901069 2 0.022
organelle assembly GO:0070925 110 0.022
regulation of response to stimulus GO:0048583 269 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
regulation of cell communication GO:0010646 232 0.021
regulation of cellular component organization GO:0051128 86 0.021
Yeast
chromosome organization involved in meiosis GO:0070192 1 0.021
protein modification by small protein removal GO:0070646 1 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
negative regulation of metabolic process GO:0009892 86 0.021
cell cycle g1 s phase transition GO:0044843 1 0.021
cellular response to starvation GO:0009267 1 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.020
cellular response to nutrient levels GO:0031669 2 0.020
negative regulation of signaling GO:0023057 96 0.020
ovulation cycle GO:0042698 2 0.020
dna biosynthetic process GO:0071897 3 0.020
mitochondrion organization GO:0007005 4 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
Yeast
cellular protein modification process GO:0006464 100 0.020
transport GO:0006810 220 0.020
female sex differentiation GO:0046660 4 0.019
regulation of developmental process GO:0050793 247 0.019
g2 m transition of mitotic cell cycle GO:0000086 4 0.019
translational initiation GO:0006413 3 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
purine containing compound metabolic process GO:0072521 29 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
oocyte anterior posterior axis specification GO:0007314 4 0.019
glycoprotein biosynthetic process GO:0009101 21 0.019
organelle fission GO:0048285 23 0.019
positive regulation of rna metabolic process GO:0051254 59 0.018
Yeast
centrosome organization GO:0051297 1 0.018
cell migration GO:0016477 237 0.018
mitotic nuclear division GO:0007067 18 0.018
macromolecule catabolic process GO:0009057 15 0.018
Yeast
localization of cell GO:0051674 244 0.018
microtubule organizing center organization GO:0031023 1 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of molecular function GO:0065009 70 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.018
Yeast
cellular macromolecular complex assembly GO:0034622 24 0.018
Yeast
positive regulation of dna templated transcription elongation GO:0032786 1 0.018
glycosyl compound metabolic process GO:1901657 11 0.018
regulation of response to external stimulus GO:0032101 31 0.017
ribonucleotide metabolic process GO:0009259 27 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
meiotic chromosome segregation GO:0045132 3 0.017
regulation of inflammatory response GO:0050727 2 0.017
purine nucleotide metabolic process GO:0006163 27 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of rna biosynthetic process GO:2001141 213 0.016
Yeast
cellular catabolic process GO:0044248 27 0.016
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.016
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
Yeast
membrane organization GO:0061024 21 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
developmental growth GO:0048589 166 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
cellular response to organic substance GO:0071310 105 0.016
establishment of localization GO:0051234 244 0.016
regulation of synapse assembly GO:0051963 3 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
regulation of growth GO:0040008 42 0.015
protein complex biogenesis GO:0070271 30 0.015
Yeast
regulation of protein import into nucleus GO:0042306 2 0.015
protein localization GO:0008104 40 0.015
camera type eye development GO:0043010 222 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
purine nucleoside metabolic process GO:0042278 10 0.015
regulation of chemotaxis GO:0050920 18 0.015
positive regulation of nucleic acid templated transcription GO:1903508 57 0.015
Yeast
regulation of cell death GO:0010941 103 0.015
single organism membrane organization GO:0044802 20 0.015
protein complex subunit organization GO:0071822 46 0.015
Yeast
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
microtubule polymerization GO:0046785 2 0.015
response to topologically incorrect protein GO:0035966 2 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
protein import GO:0017038 3 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
positive regulation of cell death GO:0010942 29 0.014
negative regulation of immune response GO:0050777 2 0.014
sensory organ development GO:0007423 393 0.014
transcription dna templated GO:0006351 181 0.014
Yeast
regulation of locomotion GO:0040012 55 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
Yeast
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
female gonad development GO:0008585 4 0.013
dna templated transcription elongation GO:0006354 3 0.013
membrane invagination GO:0010324 1 0.013
neuron development GO:0048666 262 0.013
cell cycle g2 m phase transition GO:0044839 4 0.013
multi organism process GO:0051704 134 0.013
negative regulation of nuclear division GO:0051784 3 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
regulation of organelle organization GO:0033043 29 0.013
cytoskeleton organization GO:0007010 96 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
macromolecule deacylation GO:0098732 3 0.012
ovarian follicle development GO:0001541 2 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
nucleotide metabolic process GO:0009117 28 0.012
nuclear division GO:0000280 23 0.012
nucleic acid templated transcription GO:0097659 181 0.012
Yeast
er nucleus signaling pathway GO:0006984 2 0.012
organism emergence from protective structure GO:0071684 4 0.012
anterior posterior pattern specification GO:0009952 152 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
Yeast
golgi vesicle transport GO:0048193 3 0.012
male meiosis GO:0007140 2 0.012
maturation of ssu rrna GO:0030490 1 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
Yeast
growth GO:0040007 174 0.012
regulation of immune system process GO:0002682 34 0.012
localization within membrane GO:0051668 1 0.012
heterocycle catabolic process GO:0046700 15 0.011
metallo sulfur cluster assembly GO:0031163 1 0.011
meiosis i GO:0007127 1 0.011
microtubule polymerization or depolymerization GO:0031109 3 0.011
regulation of nucleotide metabolic process GO:0006140 17 0.011
nucleoside metabolic process GO:0009116 11 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
protein complex localization GO:0031503 1 0.011
protein stabilization GO:0050821 2 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
organic acid metabolic process GO:0006082 31 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
cellular amine metabolic process GO:0044106 2 0.011
single organism biosynthetic process GO:0044711 71 0.011
interspecies interaction between organisms GO:0044419 4 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
anterior posterior axis specification GO:0009948 20 0.011
microtubule based process GO:0007017 60 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.010
phagocytosis GO:0006909 3 0.010
macromolecular complex assembly GO:0065003 35 0.010
Yeast
immune system development GO:0002520 191 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
regulation of synapse organization GO:0050807 3 0.010
purine ribonucleotide metabolic process GO:0009150 27 0.010
gene silencing GO:0016458 4 0.010
rna processing GO:0006396 25 0.010
organic substance transport GO:0071702 58 0.010

psmc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.029
disease of cellular proliferation DOID:14566 0 0.015