Danio rerio

0 known processes

kptn

kaptin (actin binding protein)

(Aliases: wu:fc13b09,wu:fc13b08,zgc:100793)

kptn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.095
negative regulation of biological process GO:0048519 304 0.065
positive regulation of transport GO:0051050 2 0.065
larval development GO:0002164 2 0.055
cellular protein catabolic process GO:0044257 4 0.051
negative regulation of cellular process GO:0048523 283 0.041
gene expression GO:0010467 252 0.039
organelle fusion GO:0048284 3 0.038
leukocyte proliferation GO:0070661 1 0.038
protein localization to plasma membrane GO:0072659 1 0.038
lipid storage GO:0019915 1 0.037
regulation of biological quality GO:0065008 263 0.037
regulation of protein complex assembly GO:0043254 3 0.037
regulation of protein transport GO:0051223 3 0.037
apoptotic process GO:0006915 116 0.036
establishment of protein localization to organelle GO:0072594 4 0.036
negative regulation of protein phosphorylation GO:0001933 4 0.034
protein polymerization GO:0051258 4 0.034
regulation of protein ubiquitination GO:0031396 3 0.033
meiotic nuclear division GO:0007126 4 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
maintenance of location GO:0051235 4 0.032
response to drug GO:0042493 3 0.032
synaptic vesicle localization GO:0097479 1 0.032
response to topologically incorrect protein GO:0035966 2 0.031
positive regulation of cell cycle GO:0045787 3 0.030
positive regulation of biological process GO:0048518 253 0.030
protein metabolic process GO:0019538 183 0.030
regulation of developmental process GO:0050793 247 0.030
regulation of primary metabolic process GO:0080090 311 0.029
response to xenobiotic stimulus GO:0009410 45 0.029
establishment of synaptic vesicle localization GO:0097480 1 0.028
cellular macromolecule metabolic process GO:0044260 391 0.028
membrane fusion GO:0061025 2 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.028
regulation of synapse organization GO:0050807 3 0.027
regulation of gene expression GO:0010468 265 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
dna templated transcription elongation GO:0006354 3 0.027
response to stress GO:0006950 263 0.027
cellular amine metabolic process GO:0044106 2 0.026
signal transduction GO:0007165 455 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.026
cellular biosynthetic process GO:0044249 286 0.025
macromolecule biosynthetic process GO:0009059 227 0.025
response to uv GO:0009411 3 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.025
response to chemical GO:0042221 320 0.025
generation of neurons GO:0048699 385 0.025
nuclear import GO:0051170 3 0.025
cell death GO:0008219 121 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
rna biosynthetic process GO:0032774 181 0.024
regulation of protein catabolic process GO:0042176 1 0.024
single organism transport GO:0044765 206 0.024
regulation of cell activation GO:0050865 1 0.024
establishment of protein localization to plasma membrane GO:0090002 1 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
mitochondrion organization GO:0007005 4 0.023
death GO:0016265 121 0.023
regulation of wound healing GO:0061041 2 0.023
immune system process GO:0002376 241 0.023
response to organic substance GO:0010033 153 0.023
cellular response to external stimulus GO:0071496 2 0.023
mononuclear cell proliferation GO:0032943 1 0.023
eye development GO:0001654 277 0.023
compound eye development GO:0048749 2 0.023
germ line stem cell maintenance GO:0030718 2 0.023
nuclear transport GO:0051169 4 0.023
positive regulation of catabolic process GO:0009896 4 0.022
protein acylation GO:0043543 3 0.022
nucleic acid metabolic process GO:0090304 244 0.022
cellular component disassembly GO:0022411 1 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
protein dephosphorylation GO:0006470 3 0.022
regulation of response to stimulus GO:0048583 269 0.022
rna metabolic process GO:0016070 219 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
locomotion GO:0040011 313 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
single organism membrane fusion GO:0044801 2 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
regulation of intracellular protein transport GO:0033157 3 0.021
stem cell proliferation GO:0072089 4 0.021
transport GO:0006810 220 0.021
regulation of reproductive process GO:2000241 4 0.021
positive regulation of cellular process GO:0048522 201 0.021
negative regulation of protein complex assembly GO:0031333 1 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
single organism metabolic process GO:0044710 217 0.020
cell part morphogenesis GO:0032990 246 0.020
adult behavior GO:0030534 2 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
phagocytosis GO:0006909 3 0.020
regulation of binding GO:0051098 3 0.020
neuroblast proliferation GO:0007405 2 0.020
chemotaxis GO:0006935 104 0.020
regulation of synapse assembly GO:0051963 3 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
amine metabolic process GO:0009308 2 0.020
protein k48 linked ubiquitination GO:0070936 1 0.020
protein secretion GO:0009306 1 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
regulation of reactive oxygen species metabolic process GO:2000377 2 0.019
central nervous system development GO:0007417 387 0.019
organelle organization GO:0006996 227 0.019
cellular response to radiation GO:0071478 4 0.019
response to abiotic stimulus GO:0009628 122 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
system process GO:0003008 185 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
hormone transport GO:0009914 2 0.019
regulation of rna metabolic process GO:0051252 224 0.019
positive regulation of dna metabolic process GO:0051054 1 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
programmed cell death GO:0012501 119 0.019
homeostatic process GO:0042592 142 0.019
regulation of dna templated transcription elongation GO:0032784 3 0.019
multicellular organism growth GO:0035264 4 0.019
lymphocyte proliferation GO:0046651 1 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
actin filament polymerization GO:0030041 2 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
protein import GO:0017038 3 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
regulation of apoptotic process GO:0042981 98 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
cellular component assembly GO:0022607 170 0.018
regulation of cytokine production GO:0001817 3 0.018
positive regulation of cell activation GO:0050867 1 0.018
nuclear migration GO:0007097 3 0.018
cell morphogenesis GO:0000902 289 0.018
cellular response to starvation GO:0009267 1 0.018
regulation of signaling GO:0023051 235 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
single organism localization GO:1902578 225 0.017
spermatid differentiation GO:0048515 2 0.017
protein polyubiquitination GO:0000209 4 0.017
neuron development GO:0048666 262 0.017
transcription dna templated GO:0006351 181 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
meiotic cell cycle process GO:1903046 3 0.017
synaptic vesicle transport GO:0048489 1 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
response to alkaloid GO:0043279 2 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
cell projection organization GO:0030030 284 0.017
sensory organ morphogenesis GO:0090596 200 0.017
b cell activation GO:0042113 2 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of circadian rhythm GO:0042752 4 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
axonogenesis GO:0007409 152 0.017
regulation of cellular metabolic process GO:0031323 320 0.016
cell aging GO:0007569 2 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
protein localization to nucleus GO:0034504 3 0.016
tube morphogenesis GO:0035239 349 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
sensory organ development GO:0007423 393 0.016
autophagy GO:0006914 4 0.016
cortical cytoskeleton organization GO:0030865 1 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
cellular response to light stimulus GO:0071482 4 0.016
biosynthetic process GO:0009058 294 0.016
regulation of metabolic process GO:0019222 359 0.016
regulation of cell shape GO:0008360 1 0.016
cellular response to xenobiotic stimulus GO:0071466 35 0.016
stem cell maintenance GO:0019827 4 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
synaptic vesicle recycling GO:0036465 1 0.016
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.016
cellular ketone metabolic process GO:0042180 11 0.016
response to external stimulus GO:0009605 264 0.016
lateral inhibition GO:0046331 1 0.016
organic substance biosynthetic process GO:1901576 289 0.016
spermatid development GO:0007286 2 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
blood vessel development GO:0001568 246 0.015
single organism nuclear import GO:1902593 3 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
protein acetylation GO:0006473 2 0.015
multi organism process GO:0051704 134 0.015
regulation of jak stat cascade GO:0046425 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
cellular response to topologically incorrect protein GO:0035967 2 0.015
stem cell division GO:0017145 1 0.015
brain development GO:0007420 293 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
regulation of protein polymerization GO:0032271 2 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
regulation of chromosome segregation GO:0051983 1 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
heterocycle metabolic process GO:0046483 290 0.015
cellular response to nutrient levels GO:0031669 2 0.015
cellular component movement GO:0006928 335 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
peptide transport GO:0015833 1 0.015
establishment of localization in cell GO:0051649 77 0.015
meiotic chromosome segregation GO:0045132 3 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
cell projection morphogenesis GO:0048858 244 0.015
cellular response to organic substance GO:0071310 105 0.014
single organism organelle organization GO:1902589 199 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
protein stabilization GO:0050821 2 0.014
protein import into nucleus GO:0006606 3 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
response to hexose GO:0009746 3 0.014
regulation of glucose transport GO:0010827 1 0.014
cellular protein metabolic process GO:0044267 129 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
nucleic acid templated transcription GO:0097659 181 0.014
lipid catabolic process GO:0016042 4 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
cellular response to stress GO:0033554 62 0.014
hemopoiesis GO:0030097 183 0.014
macromolecule deacylation GO:0098732 3 0.014
response to monosaccharide GO:0034284 3 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of biosynthetic process GO:0009889 250 0.014
regulation of tube size GO:0035150 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of cell projection assembly GO:0060491 4 0.013
protein targeting to nucleus GO:0044744 3 0.013
regulation of transcription dna templated GO:0006355 213 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
protein modification process GO:0036211 100 0.013
entrainment of circadian clock GO:0009649 2 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
homeostasis of number of cells GO:0048872 62 0.013
exocytosis GO:0006887 1 0.013
eye morphogenesis GO:0048592 144 0.013
negative regulation of cell communication GO:0010648 96 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
gtp catabolic process GO:0006184 2 0.013
centrosome organization GO:0051297 1 0.013
glucose homeostasis GO:0042593 1 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
golgi vesicle transport GO:0048193 3 0.013
double strand break repair GO:0006302 3 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
head development GO:0060322 303 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
synaptic vesicle endocytosis GO:0048488 1 0.012
lipid homeostasis GO:0055088 3 0.012
cellular respiration GO:0045333 3 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
organic acid metabolic process GO:0006082 31 0.012
establishment of localization GO:0051234 244 0.012
cell migration GO:0016477 237 0.012
response to vitamin GO:0033273 3 0.012
female gonad development GO:0008585 4 0.012
regulation of cellular component organization GO:0051128 86 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
microtubule organizing center organization GO:0031023 1 0.012
axon development GO:0061564 166 0.012
camera type eye development GO:0043010 222 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
negative regulation of signal transduction GO:0009968 94 0.012
glial cell proliferation GO:0014009 4 0.012
neurotransmitter transport GO:0006836 2 0.012
negative regulation of response to cytokine stimulus GO:0060761 2 0.012
tube closure GO:0060606 1 0.012
immune system development GO:0002520 191 0.012
sequestering of metal ion GO:0051238 3 0.012
negative regulation of secretion GO:0051048 2 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
atp catabolic process GO:0006200 4 0.012
gtp metabolic process GO:0046039 4 0.012
sequestering of calcium ion GO:0051208 3 0.012
leukocyte homeostasis GO:0001776 2 0.012
regulation of programmed cell death GO:0043067 101 0.012
rna localization GO:0006403 4 0.012
myeloid cell homeostasis GO:0002262 56 0.012
regulation of protein metabolic process GO:0051246 56 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
regulation of cell communication GO:0010646 232 0.012
regulation of inflammatory response GO:0050727 2 0.012
ameboidal type cell migration GO:0001667 143 0.012
regulation of dendrite development GO:0050773 3 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
female sex differentiation GO:0046660 4 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
protein complex disassembly GO:0043241 1 0.012
regulation of blood vessel size GO:0050880 2 0.011
localization of cell GO:0051674 244 0.011
glial cell migration GO:0008347 3 0.011
cellular component biogenesis GO:0044085 178 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of transporter activity GO:0032409 2 0.011
neuron differentiation GO:0030182 353 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of protein targeting GO:1903533 2 0.011
negative regulation of innate immune response GO:0045824 2 0.011
oxoacid metabolic process GO:0043436 31 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
positive regulation of cytokine production GO:0001819 2 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
negative regulation of immune response GO:0050777 2 0.011
negative regulation of nuclear division GO:0051784 3 0.011
secondary metabolic process GO:0019748 3 0.011
cellular localization GO:0051641 97 0.011
neutrophil migration GO:1990266 10 0.011
regulation of localization GO:0032879 104 0.011
endosomal transport GO:0016197 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
primary neural tube formation GO:0014020 1 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
monoamine transport GO:0015844 1 0.011
neutrophil mediated immunity GO:0002446 1 0.011
negative regulation of defense response GO:0031348 2 0.011
taxis GO:0042330 109 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
regulation of protein binding GO:0043393 3 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
response to nutrient GO:0007584 3 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
retina development in camera type eye GO:0060041 146 0.011
response to carbohydrate GO:0009743 3 0.011
digestive tract development GO:0048565 265 0.011
response to glucose GO:0009749 3 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
positive regulation of striated muscle tissue development GO:0045844 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
meiosis i GO:0007127 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
b cell differentiation GO:0030183 1 0.011
macromolecule modification GO:0043412 111 0.011
hormone secretion GO:0046879 2 0.010
negative chemotaxis GO:0050919 1 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
positive regulation of neuron death GO:1901216 1 0.010
microtubule polymerization or depolymerization GO:0031109 3 0.010
neuron projection morphogenesis GO:0048812 161 0.010
intracellular signal transduction GO:0035556 85 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
chromosome organization involved in meiosis GO:0070192 1 0.010
peptide metabolic process GO:0006518 1 0.010
locomotor rhythm GO:0045475 3 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
positive regulation of blood circulation GO:1903524 2 0.010
cellular protein modification process GO:0006464 100 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
neuronal action potential GO:0019228 18 0.010
pole plasm assembly GO:0007315 4 0.010
positive regulation of glucose transport GO:0010828 1 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
adherens junction organization GO:0034332 4 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
positive regulation of embryonic development GO:0040019 3 0.010
xenobiotic metabolic process GO:0006805 4 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
cell cycle arrest GO:0007050 1 0.010
activation of mapk activity GO:0000187 3 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
heart process GO:0003015 71 0.010
tissue remodeling GO:0048771 4 0.010
mitotic cytokinesis GO:0000281 3 0.010

kptn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.013