Danio rerio

0 known processes

impdh1b

inosine 5'-phosphate dehydrogenase 1b

(Aliases: wu:fa99c03,si:dkey-31f5.7,id:ibd5035,IMPDH1,wu:fa09h11,D3,zgc:113446)

impdh1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukocyte proliferation GO:0070661 1 0.152
Mouse
regulation of cell activation GO:0050865 1 0.133
aging GO:0007568 2 0.090
signal transduction GO:0007165 455 0.086
positive regulation of transport GO:0051050 2 0.084
larval development GO:0002164 2 0.080
cellular macromolecule metabolic process GO:0044260 391 0.067
establishment of protein localization to organelle GO:0072594 4 0.065
negative regulation of cellular process GO:0048523 283 0.064
mononuclear cell proliferation GO:0032943 1 0.062
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.062
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.061
regulation of nitrogen compound metabolic process GO:0051171 251 0.056
pigmentation GO:0043473 85 0.055
nucleobase containing compound biosynthetic process GO:0034654 205 0.053
Mouse
single organism localization GO:1902578 225 0.053
Fly
regulation of multicellular organismal development GO:2000026 223 0.051
neuron differentiation GO:0030182 353 0.047
Fly
single organism metabolic process GO:0044710 217 0.045
Mouse
positive regulation of cell activation GO:0050867 1 0.045
organic cyclic compound metabolic process GO:1901360 301 0.044
Mouse
gtp metabolic process GO:0046039 4 0.044
cell surface receptor signaling pathway GO:0007166 325 0.044
lymphocyte proliferation GO:0046651 1 0.043
Mouse
purine nucleotide biosynthetic process GO:0006164 20 0.042
Mouse
determination of left right symmetry GO:0007368 179 0.042
organelle organization GO:0006996 227 0.041
organic substance biosynthetic process GO:1901576 289 0.041
Mouse
digestive tract morphogenesis GO:0048546 231 0.040
b cell differentiation GO:0030183 1 0.039
guanosine containing compound metabolic process GO:1901068 4 0.039
single organism nuclear import GO:1902593 3 0.038
tube morphogenesis GO:0035239 349 0.038
digestive system development GO:0055123 289 0.038
regulation of cell communication GO:0010646 232 0.037
response to stress GO:0006950 263 0.037
regulation of developmental process GO:0050793 247 0.036
b cell activation GO:0042113 2 0.035
eye development GO:0001654 277 0.035
cellular biosynthetic process GO:0044249 286 0.035
Mouse
protein import into nucleus GO:0006606 3 0.034
regulation of neuronal synaptic plasticity GO:0048168 1 0.034
response to ketone GO:1901654 1 0.034
regulation of response to stimulus GO:0048583 269 0.033
response to uv GO:0009411 3 0.033
regulation of biological quality GO:0065008 263 0.033
protein import GO:0017038 3 0.033
response to wounding GO:0009611 116 0.033
death GO:0016265 121 0.032
cilium morphogenesis GO:0060271 85 0.032
cellular component assembly GO:0022607 170 0.031
nucleotide biosynthetic process GO:0009165 21 0.031
Mouse
cell projection assembly GO:0030031 64 0.030
immune system process GO:0002376 241 0.030
Mouse
cell proliferation GO:0008283 80 0.030
Mouse
regulation of signal transduction GO:0009966 225 0.030
biosynthetic process GO:0009058 294 0.030
Mouse
protein secretion GO:0009306 1 0.029
defense response GO:0006952 47 0.029
cell projection organization GO:0030030 284 0.029
Fly
mitochondrion organization GO:0007005 4 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
regulation of neurogenesis GO:0050767 87 0.028
digestive tract development GO:0048565 265 0.027
single organism organelle organization GO:1902589 199 0.027
cellular component assembly involved in morphogenesis GO:0010927 107 0.027
regulation of multicellular organismal process GO:0051239 277 0.026
macromolecule modification GO:0043412 111 0.026
organic acid metabolic process GO:0006082 31 0.026
regulation of cytokine production GO:0001817 3 0.026
sensory organ development GO:0007423 393 0.026
guanosine containing compound catabolic process GO:1901069 2 0.025
regulation of cell killing GO:0031341 2 0.025
positive regulation of cellular process GO:0048522 201 0.025
cellular amine metabolic process GO:0044106 2 0.025
cortical actin cytoskeleton organization GO:0030866 1 0.024
positive regulation of secretion GO:0051047 1 0.024
regulation of signaling GO:0023051 235 0.024
meiotic nuclear division GO:0007126 4 0.024
exocytosis GO:0006887 1 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.024
determination of bilateral symmetry GO:0009855 204 0.024
camera type eye development GO:0043010 222 0.024
protein metabolic process GO:0019538 183 0.023
regulation of protein transport GO:0051223 3 0.023
protein targeting to nucleus GO:0044744 3 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
Mouse
localization of cell GO:0051674 244 0.023
response to organic substance GO:0010033 153 0.023
catechol containing compound metabolic process GO:0009712 2 0.023
stem cell maintenance GO:0019827 4 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.022
stem cell proliferation GO:0072089 4 0.022
cellular protein metabolic process GO:0044267 129 0.022
positive regulation of biological process GO:0048518 253 0.022
leukocyte activation GO:0045321 12 0.022
Mouse
programmed cell death GO:0012501 119 0.022
generation of neurons GO:0048699 385 0.022
Fly
retina development in camera type eye GO:0060041 146 0.022
single organism biosynthetic process GO:0044711 71 0.021
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.021
Mouse
nucleic acid templated transcription GO:0097659 181 0.021
positive regulation of immune effector process GO:0002699 3 0.021
cell migration GO:0016477 237 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.020
Mouse
circadian regulation of gene expression GO:0032922 8 0.020
regulation of reproductive process GO:2000241 4 0.020
development of primary female sexual characteristics GO:0046545 4 0.020
amine metabolic process GO:0009308 2 0.020
embryonic organ development GO:0048568 381 0.020
organonitrogen compound biosynthetic process GO:1901566 47 0.020
Mouse
negative regulation of cell death GO:0060548 60 0.020
lymphocyte activation GO:0046649 10 0.020
Mouse
negative regulation of biological process GO:0048519 304 0.019
central nervous system development GO:0007417 387 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
mesenchyme development GO:0060485 127 0.019
meiotic cell cycle process GO:1903046 3 0.019
regulation of primary metabolic process GO:0080090 311 0.019
cilium organization GO:0044782 71 0.019
muscle cell development GO:0055001 115 0.019
nitrogen compound metabolic process GO:0006807 319 0.018
Mouse
antimicrobial humoral response GO:0019730 2 0.018
ribonucleotide biosynthetic process GO:0009260 20 0.018
compound eye development GO:0048749 2 0.018
organelle assembly GO:0070925 110 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
cilium assembly GO:0042384 58 0.018
locomotion GO:0040011 313 0.018
Fly
peptidyl lysine acetylation GO:0018394 2 0.018
nuclear transport GO:0051169 4 0.018
regulation of apoptotic process GO:0042981 98 0.018
cell cell signaling GO:0007267 52 0.018
regulation of cell death GO:0010941 103 0.018
positive regulation of dna metabolic process GO:0051054 1 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
protein acetylation GO:0006473 2 0.017
response to abiotic stimulus GO:0009628 122 0.017
female sex differentiation GO:0046660 4 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
spermatid differentiation GO:0048515 2 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
small molecule metabolic process GO:0044281 77 0.017
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
regulation of metabolic process GO:0019222 359 0.017
gene expression GO:0010467 252 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
regulation of cell differentiation GO:0045595 142 0.017
lipid storage GO:0019915 1 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
positive regulation of leukocyte differentiation GO:1902107 1 0.016
purine ribonucleoside biosynthetic process GO:0046129 2 0.016
neuron projection morphogenesis GO:0048812 161 0.016
Fly
positive regulation of catabolic process GO:0009896 4 0.016
neuron projection guidance GO:0097485 86 0.016
Fly
carbohydrate derivative metabolic process GO:1901135 61 0.016
neurotransmitter secretion GO:0007269 2 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
regulation of neurotransmitter secretion GO:0046928 1 0.016
response to external stimulus GO:0009605 264 0.016
Fly
response to drug GO:0042493 3 0.016
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.016
negative regulation of programmed cell death GO:0043069 58 0.016
dopamine metabolic process GO:0042417 2 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
Mouse
blood circulation GO:0008015 87 0.016
gtp catabolic process GO:0006184 2 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
camera type eye morphogenesis GO:0048593 108 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
positive regulation of myeloid cell differentiation GO:0045639 2 0.015
response to endogenous stimulus GO:0009719 83 0.015
nucleoside triphosphate biosynthetic process GO:0009142 2 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
maintenance of location GO:0051235 4 0.015
rna transport GO:0050658 2 0.015
cellular component biogenesis GO:0044085 178 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
cell death GO:0008219 121 0.015
regulation of protein targeting GO:1903533 2 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
secondary metabolic process GO:0019748 3 0.015
hemopoiesis GO:0030097 183 0.015
regulation of cell shape GO:0008360 1 0.014
liver development GO:0001889 96 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
chemosensory behavior GO:0007635 1 0.014
cell motility GO:0048870 244 0.014
regulation of protein complex assembly GO:0043254 3 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
nucleic acid metabolic process GO:0090304 244 0.014
heart morphogenesis GO:0003007 156 0.014
protein modification process GO:0036211 100 0.014
smooth muscle contraction GO:0006939 2 0.014
response to radiation GO:0009314 51 0.014
establishment of localization GO:0051234 244 0.014
Fly
cell cycle g1 s phase transition GO:0044843 1 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
protein polymerization GO:0051258 4 0.014
neurotransmitter transport GO:0006836 2 0.014
catecholamine biosynthetic process GO:0042423 2 0.014
dopamine biosynthetic process GO:0042416 2 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
cellular component movement GO:0006928 335 0.014
Fly
regulation of wnt signaling pathway GO:0030111 53 0.014
regulation of binding GO:0051098 3 0.014
rna localization GO:0006403 4 0.014
hepaticobiliary system development GO:0061008 98 0.014
regulation of organelle assembly GO:1902115 4 0.014
catechol containing compound biosynthetic process GO:0009713 2 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
regeneration GO:0031099 91 0.013
spermatid development GO:0007286 2 0.013
wnt signaling pathway GO:0016055 80 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
pancreas development GO:0031016 84 0.013
regulation of protein polymerization GO:0032271 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
eye morphogenesis GO:0048592 144 0.013
epithelial cell differentiation GO:0030855 116 0.013
actin filament based process GO:0030029 64 0.013
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.013
ameboidal type cell migration GO:0001667 143 0.013
transcription dna templated GO:0006351 181 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
regulation of leukocyte mediated immunity GO:0002703 1 0.013
immune system development GO:0002520 191 0.013
microtubule organizing center organization GO:0031023 1 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
positive regulation of translation GO:0045727 1 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
rna biosynthetic process GO:0032774 181 0.013
cell killing GO:0001906 2 0.013
cellular protein modification process GO:0006464 100 0.013
specification of symmetry GO:0009799 204 0.013
activation of mapk activity GO:0000187 3 0.013
regulation of immune system process GO:0002682 34 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
cell cycle arrest GO:0007050 1 0.013
synaptic vesicle transport GO:0048489 1 0.012
multi organism process GO:0051704 134 0.012
striated muscle cell development GO:0055002 108 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
single organism transport GO:0044765 206 0.012
Fly
embryonic heart tube development GO:0035050 133 0.012
response to chemical GO:0042221 320 0.012
Fly
leukocyte mediated cytotoxicity GO:0001909 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
catecholamine metabolic process GO:0006584 2 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
regulation of jun kinase activity GO:0043506 3 0.012
oligodendrocyte differentiation GO:0048709 23 0.012
response to external biotic stimulus GO:0043207 97 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
response to light stimulus GO:0009416 46 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
Mouse
negative regulation of protein transport GO:0051224 3 0.012
regulation of cell projection assembly GO:0060491 4 0.012
cellular component maintenance GO:0043954 3 0.012
negative regulation of signal transduction GO:0009968 94 0.012
regulation of synapse organization GO:0050807 3 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
pigment cell differentiation GO:0050931 38 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
melanin metabolic process GO:0006582 2 0.011
heart development GO:0007507 313 0.011
oxoacid metabolic process GO:0043436 31 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
regulation of gene expression GO:0010468 265 0.011
cellular component morphogenesis GO:0032989 336 0.011
Fly
regulation of protein import into nucleus GO:0042306 2 0.011
nucleoside biosynthetic process GO:0009163 2 0.011
regionalization GO:0003002 274 0.011
notochord development GO:0030903 54 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
heterocycle metabolic process GO:0046483 290 0.011
Mouse
epithelial tube morphogenesis GO:0060562 148 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
regulation of response to stress GO:0080134 36 0.011
negative regulation of leukocyte differentiation GO:1902106 1 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
cell projection morphogenesis GO:0048858 244 0.011
Fly
production of molecular mediator of immune response GO:0002440 2 0.011
fat soluble vitamin metabolic process GO:0006775 4 0.011
tissue remodeling GO:0048771 4 0.011
response to corticosteroid GO:0031960 1 0.011
regulation of cell proliferation GO:0042127 37 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
nucleic acid transport GO:0050657 2 0.011
cell aging GO:0007569 2 0.011
protein localization to nucleus GO:0034504 3 0.011
phenol containing compound biosynthetic process GO:0046189 4 0.011
muscle cell differentiation GO:0042692 139 0.011
regulation of programmed cell death GO:0043067 101 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of jak stat cascade GO:0046425 3 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
positive regulation of metabolic process GO:0009893 108 0.011
wound healing GO:0042060 90 0.011
regulation of protein localization to plasma membrane GO:1903076 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
multicellular organismal signaling GO:0035637 22 0.011
regulation of biosynthetic process GO:0009889 250 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
cellular response to fatty acid GO:0071398 3 0.011
positive regulation of neural precursor cell proliferation GO:2000179 1 0.011
nuclear import GO:0051170 3 0.011
lamellipodium organization GO:0097581 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
lateral inhibition GO:0046331 1 0.010
regulation of nervous system development GO:0051960 90 0.010
ribose phosphate biosynthetic process GO:0046390 20 0.010
innate immune response GO:0045087 13 0.010
response to carbohydrate GO:0009743 3 0.010
locomotor rhythm GO:0045475 3 0.010
regulation of cell development GO:0060284 100 0.010
mrna stabilization GO:0048255 4 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
striated muscle cell differentiation GO:0051146 129 0.010
purine containing compound biosynthetic process GO:0072522 20 0.010
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
organophosphate biosynthetic process GO:0090407 23 0.010
Mouse
system process GO:0003008 185 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
response to other organism GO:0051707 97 0.010
diterpenoid metabolic process GO:0016101 15 0.010
cellular response to external stimulus GO:0071496 2 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
nucleobase containing compound transport GO:0015931 2 0.010

impdh1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
musculoskeletal system disease DOID:17 0 0.021
connective tissue disease DOID:65 0 0.021
nervous system disease DOID:863 0 0.018
bone disease DOID:0080001 0 0.014
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
neuromuscular disease DOID:440 0 0.012
charcot marie tooth disease DOID:10595 0 0.012
neuropathy DOID:870 0 0.012