Danio rerio

0 known processes

tyro3

TYRO3 protein tyrosine kinase

(Aliases: dtk)

tyro3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.054
larval development GO:0002164 2 0.053
aging GO:0007568 2 0.052
morphogenesis of an epithelium GO:0002009 333 0.043
Zebrafish
signal transduction GO:0007165 455 0.039
Zebrafish Mouse
multicellular organism growth GO:0035264 4 0.037
regulation of multicellular organism growth GO:0040014 4 0.036
nitrogen compound metabolic process GO:0006807 319 0.035
maintenance of location GO:0051235 4 0.034
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.033
tube morphogenesis GO:0035239 349 0.032
Zebrafish
amine metabolic process GO:0009308 2 0.032
heterocycle metabolic process GO:0046483 290 0.032
positive regulation of transport GO:0051050 2 0.031
lipid storage GO:0019915 1 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.030
mitochondrion organization GO:0007005 4 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.028
cellular amine metabolic process GO:0044106 2 0.028
gene expression GO:0010467 252 0.028
rna metabolic process GO:0016070 219 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
regulation of meiotic cell cycle GO:0051445 1 0.028
nucleic acid metabolic process GO:0090304 244 0.028
nuclear import GO:0051170 3 0.028
cognition GO:0050890 1 0.027
meiotic cell cycle process GO:1903046 3 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
carboxylic acid metabolic process GO:0019752 22 0.026
adult behavior GO:0030534 2 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
Human Rat
regulation of protein transport GO:0051223 3 0.026
protein localization to nucleus GO:0034504 3 0.026
oxoacid metabolic process GO:0043436 31 0.026
establishment of protein localization to organelle GO:0072594 4 0.025
organic substance biosynthetic process GO:1901576 289 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
negative regulation of biological process GO:0048519 304 0.025
Zebrafish Mouse
phagocytosis GO:0006909 3 0.025
Mouse
nuclear transport GO:0051169 4 0.025
nucleocytoplasmic transport GO:0006913 4 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
Zebrafish
cellular biosynthetic process GO:0044249 286 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
regulation of cytokine production GO:0001817 3 0.023
single organism nuclear import GO:1902593 3 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
organic acid metabolic process GO:0006082 31 0.023
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
heterocycle biosynthetic process GO:0018130 215 0.022
regulation of mrna processing GO:0050684 3 0.022
regulation of primary metabolic process GO:0080090 311 0.022
positive regulation of cell cycle GO:0045787 3 0.022
positive regulation of catabolic process GO:0009896 4 0.022
transport GO:0006810 220 0.022
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.022
vasculature development GO:0001944 278 0.022
cellular ketone metabolic process GO:0042180 11 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
cellular response to external stimulus GO:0071496 2 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
biosynthetic process GO:0009058 294 0.021
response to glucose GO:0009749 3 0.021
regulation of gene expression GO:0010468 265 0.021
neuron differentiation GO:0030182 353 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
regulation of metabolic process GO:0019222 359 0.021
lateral inhibition GO:0046331 1 0.021
regulation of synapse organization GO:0050807 3 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
regulation of biosynthetic process GO:0009889 250 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
regulation of rna metabolic process GO:0051252 224 0.020
response to carbohydrate GO:0009743 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of binding GO:0051098 3 0.020
digestive system development GO:0055123 289 0.020
Zebrafish
generation of neurons GO:0048699 385 0.020
regulation of cell activation GO:0050865 1 0.020
Mouse
small molecule metabolic process GO:0044281 77 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
response to hexose GO:0009746 3 0.020
protein targeting to nucleus GO:0044744 3 0.020
digestive tract development GO:0048565 265 0.020
Zebrafish
convergent extension GO:0060026 118 0.020
Zebrafish
embryonic organ development GO:0048568 381 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
protein import GO:0017038 3 0.019
atp catabolic process GO:0006200 4 0.019
positive regulation of biological process GO:0048518 253 0.019
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
stem cell maintenance GO:0019827 4 0.019
digestive tract morphogenesis GO:0048546 231 0.019
Zebrafish
regulation of cytoplasmic transport GO:1903649 4 0.019
transcription dna templated GO:0006351 181 0.019
protein metabolic process GO:0019538 183 0.019
Human Rat
regulation of signal transduction GO:0009966 225 0.019
Mouse
response to stress GO:0006950 263 0.019
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
response to chemical GO:0042221 320 0.019
gtp metabolic process GO:0046039 4 0.019
response to nutrient GO:0007584 3 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
response to drug GO:0042493 3 0.019
single organism localization GO:1902578 225 0.019
Zebrafish Mouse
specification of symmetry GO:0009799 204 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of metal ion transport GO:0010959 4 0.018
regulation of reproductive process GO:2000241 4 0.018
establishment of localization GO:0051234 244 0.018
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
gastrulation GO:0007369 208 0.018
Zebrafish
organonitrogen compound metabolic process GO:1901564 74 0.018
protein import into nucleus GO:0006606 3 0.018
cellular protein catabolic process GO:0044257 4 0.018
cell part morphogenesis GO:0032990 246 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
head development GO:0060322 303 0.018
Mouse
cellular component morphogenesis GO:0032989 336 0.018
Mouse
meiotic chromosome segregation GO:0045132 3 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
cellular response to nutrient levels GO:0031669 2 0.018
regulation of protein complex assembly GO:0043254 3 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of response to stimulus GO:0048583 269 0.018
Mouse
nucleoside monophosphate catabolic process GO:0009125 4 0.018
negative regulation of kinase activity GO:0033673 4 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
regulation of protein targeting GO:1903533 2 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
regulation of synapse assembly GO:0051963 3 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
gtp catabolic process GO:0006184 2 0.017
brain development GO:0007420 293 0.017
Mouse
cell migration GO:0016477 237 0.017
Zebrafish Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
nucleic acid templated transcription GO:0097659 181 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
central nervous system development GO:0007417 387 0.017
Mouse
blood vessel development GO:0001568 246 0.017
heart development GO:0007507 313 0.017
regulation of cell communication GO:0010646 232 0.017
Mouse
cellular carbohydrate metabolic process GO:0044262 4 0.017
regulation of biological quality GO:0065008 263 0.017
Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.017
Zebrafish Mouse
compound eye development GO:0048749 2 0.017
cell morphogenesis GO:0000902 289 0.017
Mouse
response to monosaccharide GO:0034284 3 0.017
amino acid transport GO:0006865 2 0.017
cellular amide metabolic process GO:0043603 4 0.017
cellular component movement GO:0006928 335 0.017
Zebrafish Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
cytokinesis GO:0000910 3 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
lipid catabolic process GO:0016042 4 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
tube closure GO:0060606 1 0.016
regulation of developmental process GO:0050793 247 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
cell projection morphogenesis GO:0048858 244 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
cellular component disassembly GO:0022411 1 0.016
post embryonic organ development GO:0048569 4 0.016
single organism metabolic process GO:0044710 217 0.016
cell projection organization GO:0030030 284 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
sensory organ development GO:0007423 393 0.016
cell motility GO:0048870 244 0.016
Zebrafish Mouse
negative regulation of secretion GO:0051048 2 0.016
glucose homeostasis GO:0042593 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
positive regulation of cell activation GO:0050867 1 0.015
blood vessel morphogenesis GO:0048514 216 0.015
adherens junction organization GO:0034332 4 0.015
cellular response to starvation GO:0009267 1 0.015
regionalization GO:0003002 274 0.015
regulation of signaling GO:0023051 235 0.015
Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
secondary metabolic process GO:0019748 3 0.015
leukocyte proliferation GO:0070661 1 0.015
angiogenesis GO:0001525 158 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
fertilization GO:0009566 3 0.015
cellular component assembly GO:0022607 170 0.015
regulation of response to biotic stimulus GO:0002831 2 0.015
peptide transport GO:0015833 1 0.015
regulation of gtpase activity GO:0043087 2 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
system process GO:0003008 185 0.014
cellular component biogenesis GO:0044085 178 0.014
growth GO:0040007 174 0.014
Zebrafish
positive regulation of immune effector process GO:0002699 3 0.014
embryonic heart tube development GO:0035050 133 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
mitochondrial transport GO:0006839 2 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
positive regulation of secretion GO:0051047 1 0.014
positive regulation of cellular process GO:0048522 201 0.014
protein acetylation GO:0006473 2 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
autophagy GO:0006914 4 0.014
germ line stem cell maintenance GO:0030718 2 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
mononuclear cell proliferation GO:0032943 1 0.014
protein heterooligomerization GO:0051291 1 0.014
stem cell proliferation GO:0072089 4 0.014
interspecies interaction between organisms GO:0044419 4 0.013
female sex differentiation GO:0046660 4 0.013
Mouse
regulation of response to extracellular stimulus GO:0032104 1 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
golgi vesicle transport GO:0048193 3 0.013
apoptotic process involved in development GO:1902742 2 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
macromolecular complex disassembly GO:0032984 1 0.013
rna biosynthetic process GO:0032774 181 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
lymphocyte proliferation GO:0046651 1 0.013
single fertilization GO:0007338 3 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
immune system process GO:0002376 241 0.013
Mouse
negative regulation of nuclear division GO:0051784 3 0.013
regulation of chromosome segregation GO:0051983 1 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
hormone secretion GO:0046879 2 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
regulation of protein catabolic process GO:0042176 1 0.013
centrosome organization GO:0051297 1 0.013
carbohydrate homeostasis GO:0033500 1 0.013
organelle organization GO:0006996 227 0.013
eye development GO:0001654 277 0.013
skeletal system development GO:0001501 181 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
neurotransmitter transport GO:0006836 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
developmental programmed cell death GO:0010623 4 0.013
primary neural tube formation GO:0014020 1 0.013
regulation of calcium ion transport GO:0051924 2 0.013
rna localization GO:0006403 4 0.013
determination of left right symmetry GO:0007368 179 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
small molecule catabolic process GO:0044282 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
locomotion GO:0040011 313 0.012
Zebrafish Mouse
positive regulation of chromatin modification GO:1903310 1 0.012
regulation of transcription dna templated GO:0006355 213 0.012
nuclear export GO:0051168 1 0.012
protein complex disassembly GO:0043241 1 0.012
single organism transport GO:0044765 206 0.012
Zebrafish Mouse
epithelial tube morphogenesis GO:0060562 148 0.012
neuron projection morphogenesis GO:0048812 161 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
ear development GO:0043583 127 0.012
response to external stimulus GO:0009605 264 0.012
Mouse
cytoplasm organization GO:0007028 4 0.012
nucleic acid transport GO:0050657 2 0.012
negative regulation of reproductive process GO:2000242 3 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
response to organic substance GO:0010033 153 0.012
cellular protein metabolic process GO:0044267 129 0.012
Human Rat
negative regulation of defense response GO:0031348 2 0.012
Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.012
protein acylation GO:0043543 3 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
macromolecule modification GO:0043412 111 0.012
Human Rat
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
regulation of transporter activity GO:0032409 2 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
Zebrafish
negative regulation of secretion by cell GO:1903531 2 0.012
er to golgi vesicle mediated transport GO:0006888 1 0.012
neuron projection development GO:0031175 180 0.012
sensory organ morphogenesis GO:0090596 200 0.011
protein secretion GO:0009306 1 0.011
protein homooligomerization GO:0051260 3 0.011
exocytosis GO:0006887 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of dna replication GO:0006275 3 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
neuron development GO:0048666 262 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
nucleobase containing compound transport GO:0015931 2 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
ion transport GO:0006811 114 0.011
Zebrafish
membrane invagination GO:0010324 1 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
regulation of cell shape GO:0008360 1 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
protein stabilization GO:0050821 2 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
gland development GO:0048732 143 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
cellular localization GO:0051641 97 0.011
Zebrafish Mouse
hormone transport GO:0009914 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
regulation of inflammatory response GO:0050727 2 0.011
Mouse
negative regulation of protein complex assembly GO:0031333 1 0.011
ameboidal type cell migration GO:0001667 143 0.011
Zebrafish
regulation of blood pressure GO:0008217 1 0.011
organelle assembly GO:0070925 110 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
locomotor rhythm GO:0045475 3 0.011
chordate embryonic development GO:0043009 271 0.011
stem cell division GO:0017145 1 0.011
negative regulation of catabolic process GO:0009895 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
regulation of dendrite development GO:0050773 3 0.011
determination of bilateral symmetry GO:0009855 204 0.011
camera type eye development GO:0043010 222 0.011
endosomal transport GO:0016197 2 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
tissue remodeling GO:0048771 4 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of protein binding GO:0043393 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
cellular response to oxygen levels GO:0071453 1 0.011
regulation of blood vessel size GO:0050880 2 0.010
positive regulation of cytokine production GO:0001819 2 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
convergent extension involved in gastrulation GO:0060027 71 0.010
Zebrafish
osteoclast differentiation GO:0030316 1 0.010
regulation of cell differentiation GO:0045595 142 0.010
female gonad development GO:0008585 4 0.010
programmed cell death GO:0012501 119 0.010
Mouse
single organism organelle organization GO:1902589 199 0.010
intracellular mrna localization GO:0008298 1 0.010
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.010
neurotransmitter secretion GO:0007269 2 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
muscle structure development GO:0061061 196 0.010
actin filament polymerization GO:0030041 2 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
Zebrafish
antimicrobial humoral response GO:0019730 2 0.010
microtubule organizing center organization GO:0031023 1 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
striated muscle cell differentiation GO:0051146 129 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
regulation of hormone secretion GO:0046883 2 0.010
negative regulation of protein transport GO:0051224 3 0.010
alcohol biosynthetic process GO:0046165 2 0.010
negative regulation of cell communication GO:0010648 96 0.010
Mouse
renal system development GO:0072001 94 0.010
translational initiation GO:0006413 3 0.010

tyro3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.019
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
cardiovascular system disease DOID:1287 0 0.012
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010