Danio rerio

13 known processes

mapk10

mitogen-activated protein kinase 10

(Aliases: MGC123234,zgc:123234)

mapk10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.085
aging GO:0007568 2 0.066
Worm
adult behavior GO:0030534 2 0.058
single organism localization GO:1902578 225 0.057
Worm Fly
positive regulation of transport GO:0051050 2 0.053
signal transduction GO:0007165 455 0.051
Yeast Zebrafish Mouse Rat Worm Fly
regulation of biological quality GO:0065008 263 0.049
ion transmembrane transport GO:0034220 91 0.045
single organism transport GO:0044765 206 0.044
Worm Fly
ion transport GO:0006811 114 0.044
transport GO:0006810 220 0.043
Worm Fly
cell surface receptor signaling pathway GO:0007166 325 0.042
transmembrane transport GO:0055085 120 0.041
maintenance of location GO:0051235 4 0.039
phagocytosis GO:0006909 3 0.038
Fly
inorganic ion transmembrane transport GO:0098660 57 0.038
neuron differentiation GO:0030182 353 0.036
Fly
establishment of localization GO:0051234 244 0.036
Worm Fly
response to chemical GO:0042221 320 0.036
Yeast Fly
central nervous system development GO:0007417 387 0.035
g protein coupled receptor signaling pathway GO:0007186 74 0.034
regulation of metal ion transport GO:0010959 4 0.034
camera type eye development GO:0043010 222 0.033
response to stress GO:0006950 263 0.033
Yeast Zebrafish Mouse Rat Worm Fly
neurotransmitter transport GO:0006836 2 0.033
regulation of developmental process GO:0050793 247 0.032
Yeast
sensory organ development GO:0007423 393 0.032
regulation of metabolic process GO:0019222 359 0.031
Yeast Rat Fly
regulation of establishment of protein localization GO:0070201 4 0.031
system process GO:0003008 185 0.030
positive regulation of biological process GO:0048518 253 0.030
Yeast Fly
regulation of response to stimulus GO:0048583 269 0.030
Fly
brain development GO:0007420 293 0.029
cellular biosynthetic process GO:0044249 286 0.028
Yeast Rat
head development GO:0060322 303 0.028
cellular response to external stimulus GO:0071496 2 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
Yeast Rat Fly
monovalent inorganic cation transport GO:0015672 42 0.027
regulation of protein transport GO:0051223 3 0.027
meiotic nuclear division GO:0007126 4 0.027
response to drug GO:0042493 3 0.027
lipid storage GO:0019915 1 0.027
cellular macromolecule metabolic process GO:0044260 391 0.026
Yeast Mouse Rat Worm Fly
amine metabolic process GO:0009308 2 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
glucose homeostasis GO:0042593 1 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
positive regulation of cell cycle GO:0045787 3 0.026
small molecule metabolic process GO:0044281 77 0.025
response to abiotic stimulus GO:0009628 122 0.025
Yeast Worm Fly
embryonic organ development GO:0048568 381 0.025
Fly
exocytosis GO:0006887 1 0.025
cognition GO:0050890 1 0.024
positive regulation of catabolic process GO:0009896 4 0.024
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.024
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.024
Yeast Rat
vasculature development GO:0001944 278 0.024
sensory perception of chemical stimulus GO:0007606 3 0.024
nuclear transport GO:0051169 4 0.023
chordate embryonic development GO:0043009 271 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
Fly
guanosine containing compound metabolic process GO:1901068 4 0.023
inorganic anion transport GO:0015698 25 0.023
generation of neurons GO:0048699 385 0.023
Fly
regulation of synapse organization GO:0050807 3 0.023
organonitrogen compound metabolic process GO:1901564 74 0.022
regulation of cell communication GO:0010646 232 0.022
Fly
negative regulation of protein phosphorylation GO:0001933 4 0.022
Fly
inorganic cation transmembrane transport GO:0098662 50 0.022
gtp metabolic process GO:0046039 4 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
response to carbohydrate GO:0009743 3 0.022
organic acid metabolic process GO:0006082 31 0.022
single organism metabolic process GO:0044710 217 0.021
Yeast Zebrafish Mouse Rat Worm Fly
regulation of hormone secretion GO:0046883 2 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
regulation of cytokine production GO:0001817 3 0.021
negative regulation of cellular process GO:0048523 283 0.021
Yeast Rat Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
Yeast Rat Fly
neuron neuron synaptic transmission GO:0007270 1 0.021
regionalization GO:0003002 274 0.021
Zebrafish
cation transport GO:0006812 81 0.020
cellular protein catabolic process GO:0044257 4 0.020
cellular amine metabolic process GO:0044106 2 0.020
regulation of tube size GO:0035150 2 0.020
positive regulation of cellular process GO:0048522 201 0.020
Yeast Fly
establishment of protein localization to organelle GO:0072594 4 0.020
response to hexose GO:0009746 3 0.020
regulation of signaling GO:0023051 235 0.020
Fly
neurotransmitter secretion GO:0007269 2 0.020
hormone transport GO:0009914 2 0.020
cation transmembrane transport GO:0098655 65 0.020
eye development GO:0001654 277 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
homeostatic process GO:0042592 142 0.020
regulation of circadian rhythm GO:0042752 4 0.020
hormone secretion GO:0046879 2 0.020
embryonic organ morphogenesis GO:0048562 274 0.019
Fly
digestive tract development GO:0048565 265 0.019
Fly
cytokinesis GO:0000910 3 0.019
regulation of protein complex assembly GO:0043254 3 0.019
regulation of primary metabolic process GO:0080090 311 0.019
Yeast Rat Fly
cell projection organization GO:0030030 284 0.019
Fly
gtp catabolic process GO:0006184 2 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
Yeast Rat Fly
metal ion transport GO:0030001 58 0.019
protein localization to nucleus GO:0034504 3 0.019
digestive system development GO:0055123 289 0.019
Fly
multicellular organism growth GO:0035264 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
response to external stimulus GO:0009605 264 0.019
Fly
regulation of blood pressure GO:0008217 1 0.019
carbohydrate homeostasis GO:0033500 1 0.019
stem cell proliferation GO:0072089 4 0.019
heterocycle metabolic process GO:0046483 290 0.019
Yeast Rat
mitochondrion organization GO:0007005 4 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
Yeast Rat Fly
female sex differentiation GO:0046660 4 0.019
fluid transport GO:0042044 17 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
neuron development GO:0048666 262 0.018
Fly
negative regulation of kinase activity GO:0033673 4 0.018
Fly
negative regulation of protein kinase activity GO:0006469 4 0.018
Fly
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of reproductive process GO:2000241 4 0.018
organic substance biosynthetic process GO:1901576 289 0.018
Yeast Rat
cellular ketone metabolic process GO:0042180 11 0.018
endocrine process GO:0050886 2 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of signal transduction GO:0009966 225 0.018
Fly
determination of bilateral symmetry GO:0009855 204 0.018
Zebrafish Fly
regulation of multicellular organismal development GO:2000026 223 0.018
cellular response to starvation GO:0009267 1 0.018
gene expression GO:0010467 252 0.018
Yeast Rat
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
autophagy GO:0006914 4 0.017
Fly
response to glucose GO:0009749 3 0.017
female gonad development GO:0008585 4 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
Yeast Rat
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
protein localization to plasma membrane GO:0072659 1 0.017
meiotic cell cycle process GO:1903046 3 0.017
Yeast
regulation of blood vessel size GO:0050880 2 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
immune system process GO:0002376 241 0.017
Fly
nucleocytoplasmic transport GO:0006913 4 0.017
chemosensory behavior GO:0007635 1 0.016
cellular component movement GO:0006928 335 0.016
Worm Fly
digestive tract morphogenesis GO:0048546 231 0.016
Fly
cellular response to nutrient levels GO:0031669 2 0.016
anion transport GO:0006820 38 0.016
response to monosaccharide GO:0034284 3 0.016
regulation of endocrine process GO:0044060 2 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
positive regulation of cytokine production GO:0001819 2 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
neurological system process GO:0050877 62 0.016
sodium ion transmembrane transport GO:0035725 21 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
negative regulation of catabolic process GO:0009895 3 0.016
peptide transport GO:0015833 1 0.016
gastrulation GO:0007369 208 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of protein catabolic process GO:0042176 1 0.016
tube morphogenesis GO:0035239 349 0.016
Fly
negative regulation of biological process GO:0048519 304 0.016
Yeast Rat Fly
internal peptidyl lysine acetylation GO:0018393 2 0.016
protein acetylation GO:0006473 2 0.015
small molecule catabolic process GO:0044282 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
specification of symmetry GO:0009799 204 0.015
Zebrafish Fly
cellular component assembly GO:0022607 170 0.015
Yeast
sensory organ morphogenesis GO:0090596 200 0.015
protein import GO:0017038 3 0.015
muscle structure development GO:0061061 196 0.015
sequestering of metal ion GO:0051238 3 0.015
cellular component biogenesis GO:0044085 178 0.015
Yeast
germ line stem cell maintenance GO:0030718 2 0.015
growth GO:0040007 174 0.015
Fly
stem cell maintenance GO:0019827 4 0.015
lipid catabolic process GO:0016042 4 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
Fly
regulation of dendrite development GO:0050773 3 0.015
atp catabolic process GO:0006200 4 0.015
b cell activation GO:0042113 2 0.015
protein metabolic process GO:0019538 183 0.015
Yeast Mouse Rat Worm Fly
biosynthetic process GO:0009058 294 0.015
Yeast Rat
cellular component morphogenesis GO:0032989 336 0.015
Yeast Fly
cellular carbohydrate metabolic process GO:0044262 4 0.015
muscle cell development GO:0055001 115 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
developmental growth GO:0048589 166 0.015
Fly
sodium ion transport GO:0006814 24 0.015
heart development GO:0007507 313 0.015
compound eye development GO:0048749 2 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
leukocyte proliferation GO:0070661 1 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
Yeast Zebrafish Mouse Rat Worm Fly
i kappab kinase nf kappab signaling GO:0007249 4 0.014
organelle assembly GO:0070925 110 0.014
regulation of biosynthetic process GO:0009889 250 0.014
Yeast Rat
regulation of cellular biosynthetic process GO:0031326 245 0.014
Yeast Rat
protein polymerization GO:0051258 4 0.014
regulation of gene expression GO:0010468 265 0.014
Yeast Rat
positive regulation of secretion GO:0051047 1 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
protein homooligomerization GO:0051260 3 0.014
cell morphogenesis GO:0000902 289 0.014
Fly
positive regulation of cell activation GO:0050867 1 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
Yeast Rat
single organism nuclear import GO:1902593 3 0.014
golgi vesicle transport GO:0048193 3 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
Yeast Rat
death GO:0016265 121 0.014
endocrine hormone secretion GO:0060986 2 0.014
cell migration GO:0016477 237 0.014
Fly
negative regulation of secretion by cell GO:1903531 2 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
mononuclear cell proliferation GO:0032943 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
negative regulation of secretion GO:0051048 2 0.013
protein stabilization GO:0050821 2 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
Yeast Rat
nuclear import GO:0051170 3 0.013
dicarboxylic acid transport GO:0006835 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
Fly
cellular component disassembly GO:0022411 1 0.013
retina development in camera type eye GO:0060041 146 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
Yeast Rat
protein secretion GO:0009306 1 0.013
protein acylation GO:0043543 3 0.013
behavior GO:0007610 74 0.013
amino acid transport GO:0006865 2 0.013
lateral inhibition GO:0046331 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
cellular response to radiation GO:0071478 4 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
protein modification process GO:0036211 100 0.013
Yeast Mouse Rat Worm Fly
cellular amino acid metabolic process GO:0006520 7 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
Yeast Rat
regulation of transporter activity GO:0032409 2 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
response to wounding GO:0009611 116 0.013
Fly
phosphorus metabolic process GO:0006793 109 0.013
Yeast Zebrafish Mouse Rat Worm Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
intracellular signal transduction GO:0035556 85 0.013
Yeast Zebrafish Mouse Rat Worm Fly
synaptic vesicle transport GO:0048489 1 0.013
lymphocyte proliferation GO:0046651 1 0.013
rna metabolic process GO:0016070 219 0.013
Yeast Rat
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
protein targeting to nucleus GO:0044744 3 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
Fly
regulation of inflammatory response GO:0050727 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
response to radiation GO:0009314 51 0.012
nucleic acid metabolic process GO:0090304 244 0.012
Yeast Rat
regulation of autophagy GO:0010506 3 0.012
Fly
regulation of rna metabolic process GO:0051252 224 0.012
Yeast Rat
establishment of protein localization to plasma membrane GO:0090002 1 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
rna localization GO:0006403 4 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
Yeast Rat
cellular protein metabolic process GO:0044267 129 0.012
Yeast Mouse Rat Worm Fly
determination of left right symmetry GO:0007368 179 0.012
Fly
regulation of localization GO:0032879 104 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of muscle contraction GO:0006937 3 0.012
cellular response to light stimulus GO:0071482 4 0.012
developmental programmed cell death GO:0010623 4 0.012
axonogenesis GO:0007409 152 0.012
Fly
multicellular organismal response to stress GO:0033555 2 0.012
phototransduction GO:0007602 2 0.012
adherens junction organization GO:0034332 4 0.012
cell part morphogenesis GO:0032990 246 0.012
Fly
macromolecular complex disassembly GO:0032984 1 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
Yeast Rat
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
Yeast Rat
protein import into nucleus GO:0006606 3 0.012
regulation of binding GO:0051098 3 0.012
regulation of calcium ion transport GO:0051924 2 0.012
cell substrate adhesion GO:0031589 4 0.012
detection of stimulus GO:0051606 29 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
response to uv GO:0009411 3 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
Yeast Rat
cellular response to organic substance GO:0071310 105 0.012
carbohydrate biosynthetic process GO:0016051 1 0.011
cell motility GO:0048870 244 0.011
Fly
cell projection morphogenesis GO:0048858 244 0.011
Fly
regulation of sodium ion transport GO:0002028 2 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
Yeast Rat
neuromuscular synaptic transmission GO:0007274 2 0.011
neuroblast proliferation GO:0007405 2 0.011
positive regulation of reproductive process GO:2000243 2 0.011
synaptic vesicle localization GO:0097479 1 0.011
sequestering of calcium ion GO:0051208 3 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
Yeast Rat
determination of heart left right asymmetry GO:0061371 117 0.011
positive regulation of immune effector process GO:0002699 3 0.011
energy reserve metabolic process GO:0006112 2 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
regulation of programmed cell death GO:0043067 101 0.011
single organism organelle organization GO:1902589 199 0.011
cellular amide metabolic process GO:0043603 4 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
regulation of protein targeting GO:1903533 2 0.011
positive regulation of blood circulation GO:1903524 2 0.011
rna biosynthetic process GO:0032774 181 0.011
Yeast Rat
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
tissue remodeling GO:0048771 4 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
Yeast
regulation of synapse assembly GO:0051963 3 0.011
organelle organization GO:0006996 227 0.011
protein dephosphorylation GO:0006470 3 0.011
response to light stimulus GO:0009416 46 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
cellular protein modification process GO:0006464 100 0.011
Yeast Mouse Rat Worm Fly
water homeostasis GO:0030104 4 0.011
blood vessel development GO:0001568 246 0.011
establishment of localization in cell GO:0051649 77 0.011
Worm
gas transport GO:0015669 3 0.011
apoptotic process GO:0006915 116 0.011
response to alkaloid GO:0043279 2 0.011
response to organic substance GO:0010033 153 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
olfactory lobe development GO:0021988 4 0.011
sensory perception GO:0007600 39 0.011
segmentation GO:0035282 97 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
hemopoiesis GO:0030097 183 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
Yeast Rat
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
response to amine GO:0014075 1 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
negative regulation of defense response GO:0031348 2 0.010
fatty acid transport GO:0015908 1 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
ear development GO:0043583 127 0.010
regulation of response to nutrient levels GO:0032107 1 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
protein complex disassembly GO:0043241 1 0.010
regulation of gtpase activity GO:0043087 2 0.010
response to corticosteroid GO:0031960 1 0.010
response to other organism GO:0051707 97 0.010
Fly
positive regulation of synapse assembly GO:0051965 1 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010

mapk10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.027
musculoskeletal system disease DOID:17 0 0.014
eye disease DOID:5614 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
disease of metabolism DOID:0014667 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.010