Danio rerio

51 known processes

hnrpr

heterogeneous nuclear ribonucleoprotein R

(Aliases: zgc:56523,wu:fb97a09,wu:fe01h03)

hnrpr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal process GO:0051239 277 0.262
positive regulation of biological process GO:0048518 253 0.259
Zebrafish
negative regulation of cellular process GO:0048523 283 0.255
locomotion GO:0040011 313 0.252
embryo development ending in birth or egg hatching GO:0009792 271 0.220
Worm
alternative mrna splicing via spliceosome GO:0000380 1 0.211
regulation of metabolic process GO:0019222 359 0.210
Zebrafish Fly
cellular aromatic compound metabolic process GO:0006725 295 0.202
regulation of macromolecule metabolic process GO:0060255 317 0.201
Zebrafish Fly
larval development GO:0002164 2 0.188
organic cyclic compound metabolic process GO:1901360 301 0.186
response to chemical GO:0042221 320 0.169
maintenance of location GO:0051235 4 0.166
organelle organization GO:0006996 227 0.163
cytokinesis GO:0000910 3 0.157
localization of cell GO:0051674 244 0.153
Zebrafish
cell morphogenesis GO:0000902 289 0.149
positive regulation of gene expression GO:0010628 71 0.144
Zebrafish
regulation of gene expression GO:0010468 265 0.144
Zebrafish Fly
cell migration GO:0016477 237 0.141
Zebrafish
positive regulation of cellular process GO:0048522 201 0.131
regulation of mrna splicing via spliceosome GO:0048024 3 0.130
rna metabolic process GO:0016070 219 0.128
nucleobase containing compound metabolic process GO:0006139 274 0.125
signal transduction GO:0007165 455 0.124
regulation of cellular biosynthetic process GO:0031326 245 0.122
Fly
lipid storage GO:0019915 1 0.117
gene expression GO:0010467 252 0.117
Zebrafish Fly
regulation of multicellular organism growth GO:0040014 4 0.116
meiotic nuclear division GO:0007126 4 0.115
cell motility GO:0048870 244 0.110
Zebrafish
negative regulation of biological process GO:0048519 304 0.109
regulation of mrna processing GO:0050684 3 0.107
heterocycle biosynthetic process GO:0018130 215 0.107
regulation of nitrogen compound metabolic process GO:0051171 251 0.106
regulation of gene expression epigenetic GO:0040029 11 0.105
positive regulation of cellular component biogenesis GO:0044089 3 0.104
cellular biosynthetic process GO:0044249 286 0.103
Fly
regulation of biological quality GO:0065008 263 0.102
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.092
Fly
heterocycle metabolic process GO:0046483 290 0.091
nitrogen compound metabolic process GO:0006807 319 0.088
cellular nitrogen compound metabolic process GO:0034641 290 0.088
regulation of rna metabolic process GO:0051252 224 0.085
protein import into nucleus GO:0006606 3 0.084
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.079
cellular component assembly GO:0022607 170 0.079
rna biosynthetic process GO:0032774 181 0.079
regulation of meiotic cell cycle GO:0051445 1 0.078
regulation of nucleic acid templated transcription GO:1903506 213 0.078
positive regulation of transport GO:0051050 2 0.075
neuron projection morphogenesis GO:0048812 161 0.075
cellular component movement GO:0006928 335 0.074
response to organic substance GO:0010033 153 0.074
neuron development GO:0048666 262 0.073
nuclear import GO:0051170 3 0.068
cellular macromolecule metabolic process GO:0044260 391 0.067
Fly
mitotic nuclear division GO:0007067 18 0.066
neuron differentiation GO:0030182 353 0.064
cellular response to radiation GO:0071478 4 0.064
nucleic acid metabolic process GO:0090304 244 0.063
multicellular organism growth GO:0035264 4 0.062
female gonad development GO:0008585 4 0.061
synaptic growth at neuromuscular junction GO:0051124 2 0.061
establishment of protein localization to organelle GO:0072594 4 0.061
protein localization to nucleus GO:0034504 3 0.060
dna templated transcription elongation GO:0006354 3 0.060
stem cell maintenance GO:0019827 4 0.059
biosynthetic process GO:0009058 294 0.057
Fly
nucleic acid templated transcription GO:0097659 181 0.057
macromolecular complex subunit organization GO:0043933 74 0.056
regulation of primary metabolic process GO:0080090 311 0.056
Fly
regulation of transcription dna templated GO:0006355 213 0.056
development of primary female sexual characteristics GO:0046545 4 0.055
negative regulation of ras protein signal transduction GO:0046580 1 0.055
regulation of cell differentiation GO:0045595 142 0.054
cytoskeleton organization GO:0007010 96 0.054
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.053
aromatic compound biosynthetic process GO:0019438 217 0.052
cell projection organization GO:0030030 284 0.051
cellular macromolecule biosynthetic process GO:0034645 224 0.051
Fly
regulation of organelle assembly GO:1902115 4 0.050
regulation of protein metabolic process GO:0051246 56 0.049
Fly
cellular component morphogenesis GO:0032989 336 0.048
negative regulation of macromolecule metabolic process GO:0010605 76 0.048
rna splicing GO:0008380 16 0.047
regulation of nucleocytoplasmic transport GO:0046822 2 0.047
regulation of cytokine production GO:0001817 3 0.046
single organism nuclear import GO:1902593 3 0.046
aging GO:0007568 2 0.046
organic substance biosynthetic process GO:1901576 289 0.046
Fly
positive regulation of metabolic process GO:0009893 108 0.046
Zebrafish
organelle assembly GO:0070925 110 0.046
chromosome organization GO:0051276 31 0.045
nucleobase containing compound biosynthetic process GO:0034654 205 0.044
single organism localization GO:1902578 225 0.044
cell part morphogenesis GO:0032990 246 0.044
response to uv GO:0009411 3 0.043
negative regulation of biosynthetic process GO:0009890 55 0.043
cell morphogenesis involved in differentiation GO:0000904 195 0.043
cellular macromolecular complex assembly GO:0034622 24 0.042
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.042
Zebrafish Worm Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.042
nucleocytoplasmic transport GO:0006913 4 0.042
protein targeting to nucleus GO:0044744 3 0.042
ubiquitin dependent protein catabolic process GO:0006511 3 0.040
regulation of biosynthetic process GO:0009889 250 0.040
Fly
centrosome organization GO:0051297 1 0.040
cell projection morphogenesis GO:0048858 244 0.039
centrosome cycle GO:0007098 1 0.039
regulation of synapse assembly GO:0051963 3 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.038
regulation of protein localization to nucleus GO:1900180 2 0.038
response to external stimulus GO:0009605 264 0.037
organelle fission GO:0048285 23 0.037
cellular component disassembly GO:0022411 1 0.037
spindle assembly GO:0051225 2 0.036
multi organism cellular process GO:0044764 2 0.036
growth GO:0040007 174 0.036
oxoacid metabolic process GO:0043436 31 0.036
female sex differentiation GO:0046660 4 0.035
macromolecular complex disassembly GO:0032984 1 0.035
peptidyl serine phosphorylation GO:0018105 1 0.035
transcription from rna polymerase ii promoter GO:0006366 80 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
neuronal stem cell maintenance GO:0097150 2 0.034
generation of neurons GO:0048699 385 0.034
stem cell differentiation GO:0048863 117 0.034
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.034
regulation of establishment of protein localization GO:0070201 4 0.033
regulation of intracellular protein transport GO:0033157 3 0.033
multi organism process GO:0051704 134 0.032
Zebrafish Worm Fly
regulation of cell shape GO:0008360 1 0.032
single organism organelle organization GO:1902589 199 0.032
nuclear division GO:0000280 23 0.032
positive regulation of cytokine production GO:0001819 2 0.032
positive regulation of developmental process GO:0051094 50 0.031
regulation of cytoplasmic transport GO:1903649 4 0.031
adult behavior GO:0030534 2 0.031
regulation of developmental process GO:0050793 247 0.031
regulation of localization GO:0032879 104 0.031
Zebrafish
intracellular signal transduction GO:0035556 85 0.031
taxis GO:0042330 109 0.030
programmed cell death GO:0012501 119 0.030
Worm
positive regulation of synapse assembly GO:0051965 1 0.030
cell cycle process GO:0022402 53 0.030
regulation of synapse organization GO:0050807 3 0.030
regulation of signaling GO:0023051 235 0.030
mitotic cell cycle GO:0000278 64 0.030
regulation of cellular component organization GO:0051128 86 0.030
cell surface receptor signaling pathway GO:0007166 325 0.030
neuron projection development GO:0031175 180 0.030
protein import GO:0017038 3 0.029
cytoskeleton dependent cytokinesis GO:0061640 3 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
regulation of cell communication GO:0010646 232 0.029
regulation of protein import into nucleus GO:0042306 2 0.028
developmental growth GO:0048589 166 0.028
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.028
death GO:0016265 121 0.028
Worm
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.028
cellular component biogenesis GO:0044085 178 0.028
protein complex disassembly GO:0043241 1 0.028
cell death GO:0008219 121 0.027
Worm
locomotor rhythm GO:0045475 3 0.027
cell growth GO:0016049 57 0.027
chromatin organization GO:0006325 22 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.027
cellular response to external stimulus GO:0071496 2 0.026
negative regulation of gene expression GO:0010629 65 0.026
protein metabolic process GO:0019538 183 0.026
Fly
response to oxygen containing compound GO:1901700 55 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
negative regulation of cellular metabolic process GO:0031324 77 0.025
interspecies interaction between organisms GO:0044419 4 0.025
negative regulation of metabolic process GO:0009892 86 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
regulation of cellular protein metabolic process GO:0032268 52 0.025
Fly
regulation of protein transport GO:0051223 3 0.024
microtubule organizing center organization GO:0031023 1 0.024
response to radiation GO:0009314 51 0.023
response to stress GO:0006950 263 0.023
protein complex subunit organization GO:0071822 46 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.023
regulation of protein targeting GO:1903533 2 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
organelle localization GO:0051640 49 0.022
cellular protein catabolic process GO:0044257 4 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.022
regionalization GO:0003002 274 0.022
Fly
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.022
ribonucleoprotein complex assembly GO:0022618 5 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
Fly
reproductive process GO:0022414 40 0.021
Zebrafish Worm Fly
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.021
regulation of cellular component movement GO:0051270 55 0.021
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
gene silencing GO:0016458 4 0.021
nuclear transport GO:0051169 4 0.021
system process GO:0003008 185 0.021
Zebrafish
amine metabolic process GO:0009308 2 0.021
regulation of cell cycle GO:0051726 52 0.021
cellular response to organic substance GO:0071310 105 0.021
positive regulation of rna metabolic process GO:0051254 59 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
cellular amine metabolic process GO:0044106 2 0.021
protein polymerization GO:0051258 4 0.021
viral process GO:0016032 1 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
negative regulation of nuclear division GO:0051784 3 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
positive regulation of multicellular organismal process GO:0051240 52 0.020
microtubule polymerization GO:0046785 2 0.020
compound eye development GO:0048749 2 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.019
single organism transport GO:0044765 206 0.019
regulation of response to stimulus GO:0048583 269 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
stem cell proliferation GO:0072089 4 0.019
positive regulation of rna biosynthetic process GO:1902680 57 0.019
macromolecular complex assembly GO:0065003 35 0.019
meiotic cell cycle process GO:1903046 3 0.019
phosphorus metabolic process GO:0006793 109 0.018
apoptotic process GO:0006915 116 0.018
Worm
negative regulation of nucleic acid templated transcription GO:1903507 45 0.018
microtubule cytoskeleton organization GO:0000226 33 0.018
peptidyl serine modification GO:0018209 2 0.018
response to light stimulus GO:0009416 46 0.018
response to lipid GO:0033993 60 0.018
regulation of stem cell differentiation GO:2000736 4 0.018
single organism reproductive process GO:0044702 40 0.017
Zebrafish Worm Fly
transport GO:0006810 220 0.017
positive regulation of catabolic process GO:0009896 4 0.017
acylglycerol homeostasis GO:0055090 2 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
sex determination GO:0007530 1 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
histone h3 k4 methylation GO:0051568 2 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
negative regulation of developmental process GO:0051093 65 0.016
establishment of localization GO:0051234 244 0.016
response to cold GO:0009409 4 0.016
regulation of circadian rhythm GO:0042752 4 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
circulatory system process GO:0003013 87 0.016
Zebrafish
lipid homeostasis GO:0055088 3 0.016
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.016
positive regulation of epithelial cell proliferation GO:0050679 1 0.016
protein methylation GO:0006479 13 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
cellular response to light stimulus GO:0071482 4 0.016
regulation of microtubule cytoskeleton organization GO:0070507 3 0.016
positive regulation of dna templated transcription elongation GO:0032786 1 0.016
macromolecule localization GO:0033036 54 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.016
neuroblast proliferation GO:0007405 2 0.015
regulation of cell activation GO:0050865 1 0.015
organism emergence from protective structure GO:0071684 4 0.015
protein localization GO:0008104 40 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
gamete generation GO:0007276 33 0.015
Zebrafish Worm Fly
meiotic chromosome segregation GO:0045132 3 0.015
regulation of cell motility GO:2000145 46 0.015
Zebrafish
protein complex assembly GO:0006461 30 0.015
negative regulation of mitosis GO:0045839 3 0.014
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.014
response to drug GO:0042493 3 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
regulation of autophagy GO:0010506 3 0.014
limb bud formation GO:0060174 2 0.014
positive regulation of jak stat cascade GO:0046427 2 0.014
response to external biotic stimulus GO:0043207 97 0.014
eye development GO:0001654 277 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
response to hormone GO:0009725 48 0.014
hemopoiesis GO:0030097 183 0.014
negative regulation of defense response GO:0031348 2 0.014
regulation of cell division GO:0051302 12 0.014
regulation of developmental growth GO:0048638 38 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
cell cycle GO:0007049 93 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
meiosis i GO:0007127 1 0.014
cellular protein modification process GO:0006464 100 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
developmental cell growth GO:0048588 52 0.014
transcription dna templated GO:0006351 181 0.014
regulation of protein complex disassembly GO:0043244 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
regulation of protein complex assembly GO:0043254 3 0.013
protein alkylation GO:0008213 13 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
cell proliferation GO:0008283 80 0.013
phagocytosis GO:0006909 3 0.013
response to abiotic stimulus GO:0009628 122 0.013
spermatid differentiation GO:0048515 2 0.013
phosphorylation GO:0016310 69 0.013
regulation of organelle organization GO:0033043 29 0.013
muscle cell differentiation GO:0042692 139 0.013
regulation of dna templated transcription elongation GO:0032784 3 0.013
developmental programmed cell death GO:0010623 4 0.013
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
protein stabilization GO:0050821 2 0.013
posttranscriptional gene silencing by rna GO:0035194 3 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
regulation of protein catabolic process GO:0042176 1 0.013
negative regulation of translation GO:0017148 1 0.013
rna 3 end processing GO:0031123 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
negative regulation of multi organism process GO:0043901 3 0.013
spermatid development GO:0007286 2 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
stem cell development GO:0048864 82 0.013
regulation of dendrite development GO:0050773 3 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
regulation of reproductive process GO:2000241 4 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
single organism metabolic process GO:0044710 217 0.012
regulation of jak stat cascade GO:0046425 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
mitotic cell cycle process GO:1903047 48 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
sensory organ development GO:0007423 393 0.012
wnt signaling pathway GO:0016055 80 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
Fly
dsrna fragmentation GO:0031050 1 0.012
posttranscriptional regulation of gene expression GO:0010608 14 0.012
Zebrafish Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
axon development GO:0061564 166 0.012
protein depolymerization GO:0051261 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
positive regulation of signaling GO:0023056 56 0.012
regulation of growth GO:0040008 42 0.012
regulation of nervous system development GO:0051960 90 0.012
immune system process GO:0002376 241 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
gene silencing by rna GO:0031047 4 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
multi organism reproductive process GO:0044703 36 0.011
Zebrafish Worm Fly
negative regulation of synapse assembly GO:0051964 2 0.011
regulation of epidermis development GO:0045682 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
Fly
somatic muscle development GO:0007525 4 0.011
cellular response to starvation GO:0009267 1 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
muscle cell development GO:0055001 115 0.011
mitochondrion organization GO:0007005 4 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
entrainment of circadian clock GO:0009649 2 0.011
cell substrate junction assembly GO:0007044 2 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
mrna metabolic process GO:0016071 20 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of locomotion GO:0040012 55 0.011
Zebrafish
mitotic cytokinesis GO:0000281 3 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
tissue remodeling GO:0048771 4 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
vasculature development GO:0001944 278 0.010
heart process GO:0003015 71 0.010
Zebrafish
negative regulation of reproductive process GO:2000242 3 0.010
b cell activation GO:0042113 2 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
wound healing GO:0042060 90 0.010
small molecule metabolic process GO:0044281 77 0.010
organic acid metabolic process GO:0006082 31 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010

hnrpr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.040
disease of cellular proliferation DOID:14566 0 0.040
organ system cancer DOID:0050686 0 0.040
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.014