Danio rerio

0 known processes

LOC566998

novel protein similar to vertebrate phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) (PDE4D)

LOC566998 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.058
larval development GO:0002164 2 0.049
aging GO:0007568 2 0.047
cellular macromolecule metabolic process GO:0044260 391 0.038
positive regulation of transport GO:0051050 2 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.034
multicellular organism growth GO:0035264 4 0.034
phagocytosis GO:0006909 3 0.034
regulation of cytokine production GO:0001817 3 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
nitrogen compound metabolic process GO:0006807 319 0.033
nuclear transport GO:0051169 4 0.033
regulation of protein transport GO:0051223 3 0.031
sensory organ development GO:0007423 393 0.031
establishment of protein localization to organelle GO:0072594 4 0.030
amine metabolic process GO:0009308 2 0.030
response to monosaccharide GO:0034284 3 0.030
cellular carbohydrate metabolic process GO:0044262 4 0.029
autophagy GO:0006914 4 0.029
heterocycle biosynthetic process GO:0018130 215 0.029
response to carbohydrate GO:0009743 3 0.029
adult behavior GO:0030534 2 0.029
maintenance of location GO:0051235 4 0.029
cellular response to external stimulus GO:0071496 2 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
response to chemical GO:0042221 320 0.029
transport GO:0006810 220 0.028
heterocycle metabolic process GO:0046483 290 0.028
head development GO:0060322 303 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
cellular response to nutrient levels GO:0031669 2 0.028
cellular biosynthetic process GO:0044249 286 0.028
organic substance biosynthetic process GO:1901576 289 0.028
cell projection morphogenesis GO:0048858 244 0.028
brain development GO:0007420 293 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
lipid storage GO:0019915 1 0.027
protein metabolic process GO:0019538 183 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
regulation of biosynthetic process GO:0009889 250 0.027
cellular response to starvation GO:0009267 1 0.026
eye development GO:0001654 277 0.026
protein targeting to nucleus GO:0044744 3 0.026
signal transduction GO:0007165 455 0.026
female sex differentiation GO:0046660 4 0.026
rna metabolic process GO:0016070 219 0.025
biosynthetic process GO:0009058 294 0.025
protein import GO:0017038 3 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
regulation of biological quality GO:0065008 263 0.024
embryonic organ development GO:0048568 381 0.024
protein localization to nucleus GO:0034504 3 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
regulation of inflammatory response GO:0050727 2 0.024
positive regulation of catabolic process GO:0009896 4 0.024
nucleic acid templated transcription GO:0097659 181 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
neuron differentiation GO:0030182 353 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
positive regulation of cell cycle GO:0045787 3 0.023
cellular protein catabolic process GO:0044257 4 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
cellular amine metabolic process GO:0044106 2 0.023
response to glucose GO:0009749 3 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
glucose homeostasis GO:0042593 1 0.023
response to hexose GO:0009746 3 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
response to drug GO:0042493 3 0.023
meiotic nuclear division GO:0007126 4 0.023
response to stress GO:0006950 263 0.023
single organism nuclear import GO:1902593 3 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
single organism transport GO:0044765 206 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of primary metabolic process GO:0080090 311 0.022
meiotic cell cycle process GO:1903046 3 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
response to external stimulus GO:0009605 264 0.022
neuron development GO:0048666 262 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
nucleoside monophosphate catabolic process GO:0009125 4 0.022
regulation of response to stimulus GO:0048583 269 0.022
nucleic acid metabolic process GO:0090304 244 0.021
transcription dna templated GO:0006351 181 0.021
regulation of protein complex assembly GO:0043254 3 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
mitochondrion organization GO:0007005 4 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
positive regulation of biological process GO:0048518 253 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
regulation of binding GO:0051098 3 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
cell part morphogenesis GO:0032990 246 0.021
peptide transport GO:0015833 1 0.021
leukocyte proliferation GO:0070661 1 0.021
cellular ketone metabolic process GO:0042180 11 0.021
cell morphogenesis GO:0000902 289 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
single organism metabolic process GO:0044710 217 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
smooth muscle contraction GO:0006939 2 0.020
regulation of mrna processing GO:0050684 3 0.020
negative regulation of cellular process GO:0048523 283 0.020
regulation of synapse organization GO:0050807 3 0.020
small molecule metabolic process GO:0044281 77 0.020
regulation of synapse assembly GO:0051963 3 0.020
protein import into nucleus GO:0006606 3 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
establishment of localization GO:0051234 244 0.020
amino acid transport GO:0006865 2 0.020
nuclear import GO:0051170 3 0.020
negative regulation of secretion GO:0051048 2 0.020
regulation of cellular metabolic process GO:0031323 320 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
locomotion GO:0040011 313 0.019
negative regulation of biological process GO:0048519 304 0.019
regulation of organelle assembly GO:1902115 4 0.019
cellular component disassembly GO:0022411 1 0.019
generation of neurons GO:0048699 385 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of autophagy GO:0010506 3 0.019
hormone transport GO:0009914 2 0.019
regulation of developmental process GO:0050793 247 0.019
digestive system development GO:0055123 289 0.019
organic acid metabolic process GO:0006082 31 0.019
specification of symmetry GO:0009799 204 0.019
atp catabolic process GO:0006200 4 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
camera type eye development GO:0043010 222 0.019
heart development GO:0007507 313 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
lipid homeostasis GO:0055088 3 0.018
regulation of reproductive process GO:2000241 4 0.018
cellular component movement GO:0006928 335 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
regulation of cell activation GO:0050865 1 0.018
mononuclear cell proliferation GO:0032943 1 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
female gonad development GO:0008585 4 0.018
blood vessel development GO:0001568 246 0.018
response to nutrient GO:0007584 3 0.018
negative regulation of neural precursor cell proliferation GO:2000178 1 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
regulation of signal transduction GO:0009966 225 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
cognition GO:0050890 1 0.018
regulation of metal ion transport GO:0010959 4 0.018
protein acetylation GO:0006473 2 0.018
development of primary female sexual characteristics GO:0046545 4 0.017
oxoacid metabolic process GO:0043436 31 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
liver development GO:0001889 96 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
carbohydrate homeostasis GO:0033500 1 0.017
cell projection organization GO:0030030 284 0.017
tube morphogenesis GO:0035239 349 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
rna biosynthetic process GO:0032774 181 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of protein targeting GO:1903533 2 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
vasculature development GO:0001944 278 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
hormone secretion GO:0046879 2 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
regulation of cell communication GO:0010646 232 0.017
macroautophagy GO:0016236 1 0.017
cellular component morphogenesis GO:0032989 336 0.017
single organism localization GO:1902578 225 0.017
organelle organization GO:0006996 227 0.016
negative regulation of protein transport GO:0051224 3 0.016
regulation of hormone secretion GO:0046883 2 0.016
negative regulation of catabolic process GO:0009895 3 0.016
positive regulation of immune effector process GO:0002699 3 0.016
regulation of protein catabolic process GO:0042176 1 0.016
gtp catabolic process GO:0006184 2 0.016
cell migration GO:0016477 237 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
rna localization GO:0006403 4 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
lateral inhibition GO:0046331 1 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
lymphocyte proliferation GO:0046651 1 0.016
negative regulation of cytoplasmic transport GO:1903650 2 0.016
stem cell maintenance GO:0019827 4 0.016
gtp metabolic process GO:0046039 4 0.016
cell matrix adhesion GO:0007160 4 0.016
protein acylation GO:0043543 3 0.016
negative regulation of intracellular transport GO:0032387 3 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
regulation of rna metabolic process GO:0051252 224 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
negative regulation of secretion by cell GO:1903531 2 0.015
positive regulation of cell activation GO:0050867 1 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
protein secretion GO:0009306 1 0.015
negative regulation of cytokine production GO:0001818 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
microtubule organizing center organization GO:0031023 1 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
energy reserve metabolic process GO:0006112 2 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
negative regulation of defense response GO:0031348 2 0.015
compound eye development GO:0048749 2 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
neurotransmitter transport GO:0006836 2 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
response to topologically incorrect protein GO:0035966 2 0.015
protein localization to plasma membrane GO:0072659 1 0.015
protein heterooligomerization GO:0051291 1 0.015
gastrulation GO:0007369 208 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
digestive tract development GO:0048565 265 0.015
macromolecular complex disassembly GO:0032984 1 0.015
regulation of blood vessel size GO:0050880 2 0.015
immune system process GO:0002376 241 0.015
positive regulation of cellular process GO:0048522 201 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
organic substance transport GO:0071702 58 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
determination of bilateral symmetry GO:0009855 204 0.014
system process GO:0003008 185 0.014
phagocytosis engulfment GO:0006911 1 0.014
regulation of signaling GO:0023051 235 0.014
interspecies interaction between organisms GO:0044419 4 0.014
chemosensory behavior GO:0007635 1 0.014
digestive tract morphogenesis GO:0048546 231 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
transmembrane transport GO:0055085 120 0.014
regionalization GO:0003002 274 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
somatic muscle development GO:0007525 4 0.014
olfactory lobe development GO:0021988 4 0.014
determination of left right symmetry GO:0007368 179 0.014
synaptic vesicle localization GO:0097479 1 0.014
regulation of transcription dna templated GO:0006355 213 0.014
angiogenesis GO:0001525 158 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
positive regulation of cytokine production GO:0001819 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
protein polymerization GO:0051258 4 0.014
regulation of blood pressure GO:0008217 1 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
axonogenesis GO:0007409 152 0.013
regulation of circadian rhythm GO:0042752 4 0.013
protein complex disassembly GO:0043241 1 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
response to ketone GO:1901654 1 0.013
forebrain cell migration GO:0021885 1 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
gene expression GO:0010467 252 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
response to wounding GO:0009611 116 0.013
single organism organelle organization GO:1902589 199 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
response to vitamin GO:0033273 3 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
response to uv GO:0009411 3 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
response to abiotic stimulus GO:0009628 122 0.013
actin filament polymerization GO:0030041 2 0.013
regulation of metabolic process GO:0019222 359 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
multi organism cellular process GO:0044764 2 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
response to alkaloid GO:0043279 2 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
stem cell proliferation GO:0072089 4 0.013
protein homooligomerization GO:0051260 3 0.013
mechanosensory behavior GO:0007638 2 0.013
regulation of rna biosynthetic process GO:2001141 213 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of cell shape GO:0008360 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
regulation of muscle contraction GO:0006937 3 0.012
post embryonic organ development GO:0048569 4 0.012
cellular protein metabolic process GO:0044267 129 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
negative chemotaxis GO:0050919 1 0.012
cellular component biogenesis GO:0044085 178 0.012
cellular amide metabolic process GO:0043603 4 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
single organism biosynthetic process GO:0044711 71 0.012
cilium assembly GO:0042384 58 0.012
lipid catabolic process GO:0016042 4 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
membrane invagination GO:0010324 1 0.012
neuron projection development GO:0031175 180 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
programmed cell death GO:0012501 119 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
regulation of protein polymerization GO:0032271 2 0.012
leukocyte mediated cytotoxicity GO:0001909 1 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
alternative mrna splicing via spliceosome GO:0000380 1 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
cilium organization GO:0044782 71 0.012
membrane lipid biosynthetic process GO:0046467 2 0.012
exocytosis GO:0006887 1 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
regulation of gene expression GO:0010468 265 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
peptidyl serine modification GO:0018209 2 0.012
regulation of cell projection assembly GO:0060491 4 0.012
neuroblast proliferation GO:0007405 2 0.012
axon development GO:0061564 166 0.012
secondary metabolic process GO:0019748 3 0.012
nuclear export GO:0051168 1 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.011
regulation of tube size GO:0035150 2 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
cell motility GO:0048870 244 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
blood vessel morphogenesis GO:0048514 216 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
regulation of cell differentiation GO:0045595 142 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
cell substrate adhesion GO:0031589 4 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of calcium ion transport GO:0051924 2 0.011
ion transmembrane transport GO:0034220 91 0.011
death GO:0016265 121 0.011
b cell activation GO:0042113 2 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
localization of cell GO:0051674 244 0.011
organism emergence from protective structure GO:0071684 4 0.011
inner ear development GO:0048839 126 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
sensory organ morphogenesis GO:0090596 200 0.011
tissue remodeling GO:0048771 4 0.011
anterior posterior pattern specification GO:0009952 152 0.011
regulation of dendrite development GO:0050773 3 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
regulation of glucose transport GO:0010827 1 0.011
apoptotic process GO:0006915 116 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
growth GO:0040007 174 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
locomotor rhythm GO:0045475 3 0.011
hatching GO:0035188 4 0.011
response to corticosteroid GO:0031960 1 0.011
outflow tract morphogenesis GO:0003151 1 0.011
regulation of protein binding GO:0043393 3 0.011
hepaticobiliary system development GO:0061008 98 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
lamellipodium assembly GO:0030032 1 0.010
cilium morphogenesis GO:0060271 85 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
tube closure GO:0060606 1 0.010
antimicrobial humoral response GO:0019730 2 0.010
hemopoiesis GO:0030097 183 0.010
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.010
cytokinesis GO:0000910 3 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
response to amino acid GO:0043200 2 0.010
regulation of transporter activity GO:0032409 2 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
canonical wnt signaling pathway GO:0060070 48 0.010
cellular response to oxygen levels GO:0071453 1 0.010
response to organic substance GO:0010033 153 0.010
protein stabilization GO:0050821 2 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
astrocyte differentiation GO:0048708 1 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010

LOC566998 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
musculoskeletal system disease DOID:17 0 0.026
cardiovascular system disease DOID:1287 0 0.016
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
disease of metabolism DOID:0014667 0 0.013
organ system cancer DOID:0050686 0 0.012
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011