Danio rerio

20 known processes

cyp2k6

cytochrome P450, family 2, subfamily K, polypeptide 6

(Aliases: zgc:66225,MGC66225)

cyp2k6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.179
Worm
single organism transport GO:0044765 206 0.125
small molecule metabolic process GO:0044281 77 0.089
response to chemical GO:0042221 320 0.083
Worm
single organism metabolic process GO:0044710 217 0.076
larval development GO:0002164 2 0.076
heterocycle metabolic process GO:0046483 290 0.069
cellular aromatic compound metabolic process GO:0006725 295 0.067
nitrogen compound metabolic process GO:0006807 319 0.066
central nervous system development GO:0007417 387 0.065
biosynthetic process GO:0009058 294 0.064
organic cyclic compound biosynthetic process GO:1901362 223 0.063
lipid storage GO:0019915 1 0.054
Worm
meiotic nuclear division GO:0007126 4 0.053
nucleobase containing compound metabolic process GO:0006139 274 0.052
organic cyclic compound metabolic process GO:1901360 301 0.051
single organism localization GO:1902578 225 0.050
response to xenobiotic stimulus GO:0009410 45 0.050
Worm
organic substance biosynthetic process GO:1901576 289 0.048
regulation of rna metabolic process GO:0051252 224 0.046
positive regulation of transport GO:0051050 2 0.045
cellular amine metabolic process GO:0044106 2 0.045
single organism organelle organization GO:1902589 199 0.045
cellular nitrogen compound metabolic process GO:0034641 290 0.044
cellular macromolecule metabolic process GO:0044260 391 0.044
establishment of localization GO:0051234 244 0.043
heart development GO:0007507 313 0.043
cellular response to chemical stimulus GO:0070887 157 0.041
regulation of biosynthetic process GO:0009889 250 0.041
sensory organ development GO:0007423 393 0.040
nucleic acid metabolic process GO:0090304 244 0.039
embryonic organ development GO:0048568 381 0.039
multicellular organism growth GO:0035264 4 0.038
signal transduction GO:0007165 455 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.037
response to organic substance GO:0010033 153 0.037
adult behavior GO:0030534 2 0.036
regulation of biological quality GO:0065008 263 0.035
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
response to drug GO:0042493 3 0.033
cellular nitrogen compound biosynthetic process GO:0044271 218 0.033
cellular biosynthetic process GO:0044249 286 0.033
regulation of metabolic process GO:0019222 359 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
catecholamine metabolic process GO:0006584 2 0.032
organonitrogen compound metabolic process GO:1901564 74 0.031
cellular response to organic cyclic compound GO:0071407 38 0.030
segmentation GO:0035282 97 0.030
transmembrane transport GO:0055085 120 0.030
immune system process GO:0002376 241 0.030
Worm
maintenance of location GO:0051235 4 0.030
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.030
oxoacid metabolic process GO:0043436 31 0.030
cellular amino acid metabolic process GO:0006520 7 0.029
cellular response to endogenous stimulus GO:0071495 68 0.029
transcription dna templated GO:0006351 181 0.028
cellular ketone metabolic process GO:0042180 11 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
determination of bilateral symmetry GO:0009855 204 0.028
amine metabolic process GO:0009308 2 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
stem cell proliferation GO:0072089 4 0.028
response to steroid hormone GO:0048545 35 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.027
regulation of reproductive process GO:2000241 4 0.027
regulation of developmental process GO:0050793 247 0.027
transport GO:0006810 220 0.027
cellular protein catabolic process GO:0044257 4 0.026
proteasomal protein catabolic process GO:0010498 2 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
tissue remodeling GO:0048771 4 0.026
regulation of cell activation GO:0050865 1 0.026
organic acid metabolic process GO:0006082 31 0.026
tube morphogenesis GO:0035239 349 0.026
response to estrogen GO:0043627 27 0.026
organelle organization GO:0006996 227 0.026
cellular response to hormone stimulus GO:0032870 39 0.026
positive regulation of cell activation GO:0050867 1 0.026
developmental growth GO:0048589 166 0.025
cellular response to steroid hormone stimulus GO:0071383 31 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
gene expression GO:0010467 252 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
response to glucocorticoid GO:0051384 1 0.024
phagocytosis GO:0006909 3 0.024
single fertilization GO:0007338 3 0.024
secondary metabolic process GO:0019748 3 0.023
regulation of binding GO:0051098 3 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
cellular response to external stimulus GO:0071496 2 0.023
eye development GO:0001654 277 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
negative regulation of gene expression GO:0010629 65 0.023
head development GO:0060322 303 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
rna biosynthetic process GO:0032774 181 0.023
growth GO:0040007 174 0.023
positive regulation of cytokine production GO:0001819 2 0.022
fertilization GO:0009566 3 0.022
negative regulation of cellular process GO:0048523 283 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
cellular component assembly GO:0022607 170 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
aromatic compound biosynthetic process GO:0019438 217 0.021
ion transmembrane transport GO:0034220 91 0.021
regulation of transcription dna templated GO:0006355 213 0.021
response to endogenous stimulus GO:0009719 83 0.021
meiotic cell cycle process GO:1903046 3 0.021
mononuclear cell proliferation GO:0032943 1 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
negative regulation of biological process GO:0048519 304 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
response to external stimulus GO:0009605 264 0.021
immune system development GO:0002520 191 0.020
hemopoiesis GO:0030097 183 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
regulation of gene expression GO:0010468 265 0.020
phosphorus metabolic process GO:0006793 109 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
rna metabolic process GO:0016070 219 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
gastrulation GO:0007369 208 0.020
brain development GO:0007420 293 0.020
response to corticosteroid GO:0031960 1 0.020
translational initiation GO:0006413 3 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.019
response to abiotic stimulus GO:0009628 122 0.019
positive regulation of cell communication GO:0010647 56 0.019
digestive system development GO:0055123 289 0.019
urogenital system development GO:0001655 97 0.019
response to stress GO:0006950 263 0.019
Worm
positive regulation of secretion GO:0051047 1 0.019
positive regulation of signaling GO:0023056 56 0.019
specification of symmetry GO:0009799 204 0.019
leukocyte proliferation GO:0070661 1 0.019
cellular response to organic substance GO:0071310 105 0.019
positive regulation of secretion by cell GO:1903532 1 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
female sex differentiation GO:0046660 4 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
cellular component movement GO:0006928 335 0.018
cation transmembrane transport GO:0098655 65 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
cell morphogenesis GO:0000902 289 0.018
epithelial cell differentiation GO:0030855 116 0.018
hormone transport GO:0009914 2 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
positive regulation of biological process GO:0048518 253 0.018
cellular response to estrogen stimulus GO:0071391 24 0.018
response to monosaccharide GO:0034284 3 0.018
sleep GO:0030431 1 0.018
digestive tract development GO:0048565 265 0.017
hormone metabolic process GO:0042445 19 0.017
regulation of circadian rhythm GO:0042752 4 0.017
camera type eye development GO:0043010 222 0.017
determination of left right symmetry GO:0007368 179 0.017
cellular response to lipid GO:0071396 39 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
heart looping GO:0001947 94 0.016
regulation of jak stat cascade GO:0046425 3 0.016
embryonic heart tube development GO:0035050 133 0.016
regulation of blood pressure GO:0008217 1 0.016
atp catabolic process GO:0006200 4 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
positive regulation of cell cycle GO:0045787 3 0.016
nuclear transport GO:0051169 4 0.016
regulation of metal ion transport GO:0010959 4 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
regulation of response to stimulus GO:0048583 269 0.016
positive regulation of catabolic process GO:0009896 4 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of cytokine production GO:0001817 3 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
renal system development GO:0072001 94 0.015
response to uv GO:0009411 3 0.015
ion transport GO:0006811 114 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
locomotion GO:0040011 313 0.015
Worm
regulation of meiotic cell cycle GO:0051445 1 0.015
response to light stimulus GO:0009416 46 0.015
regulation of protein complex assembly GO:0043254 3 0.015
lymphocyte proliferation GO:0046651 1 0.015
muscle structure development GO:0061061 196 0.015
cell projection morphogenesis GO:0048858 244 0.015
regionalization GO:0003002 274 0.015
stem cell maintenance GO:0019827 4 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
response to carbohydrate GO:0009743 3 0.015
muscle tissue development GO:0060537 110 0.015
liver development GO:0001889 96 0.014
negative regulation of nuclear division GO:0051784 3 0.014
death GO:0016265 121 0.014
digestive tract morphogenesis GO:0048546 231 0.014
regulation of molecular function GO:0065009 70 0.014
chemosensory behavior GO:0007635 1 0.014
leukocyte homeostasis GO:0001776 2 0.014
meiosis i GO:0007127 1 0.014
mitochondrion organization GO:0007005 4 0.014
cellular response to nutrient levels GO:0031669 2 0.014
chordate embryonic development GO:0043009 271 0.014
androgen metabolic process GO:0008209 2 0.014
response to topologically incorrect protein GO:0035966 2 0.014
response to nutrient GO:0007584 3 0.014
hepaticobiliary system development GO:0061008 98 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
cellular response to xenobiotic stimulus GO:0071466 35 0.014
protein metabolic process GO:0019538 183 0.014
catechol containing compound metabolic process GO:0009712 2 0.014
regulation of translational initiation GO:0006446 1 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
developmental programmed cell death GO:0010623 4 0.013
generation of neurons GO:0048699 385 0.013
response to lipid GO:0033993 60 0.013
regulation of primary metabolic process GO:0080090 311 0.013
nucleic acid templated transcription GO:0097659 181 0.013
immune response GO:0006955 28 0.013
Worm
regulation of growth rate GO:0040009 1 0.013
multi organism process GO:0051704 134 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of transport GO:0051049 45 0.013
oxidation reduction process GO:0055114 41 0.013
protein import GO:0017038 3 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
multicellular organismal response to stress GO:0033555 2 0.013
regulation of sodium ion transport GO:0002028 2 0.013
regulation of inflammatory response GO:0050727 2 0.013
regulation of tube size GO:0035150 2 0.013
female gonad development GO:0008585 4 0.013
defense response GO:0006952 47 0.012
Worm
establishment of protein localization to organelle GO:0072594 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
small molecule catabolic process GO:0044282 3 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
protein import into nucleus GO:0006606 3 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
regulation of cell communication GO:0010646 232 0.012
hormone secretion GO:0046879 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
blood vessel development GO:0001568 246 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of protein transport GO:0051223 3 0.012
nuclear import GO:0051170 3 0.012
protein acetylation GO:0006473 2 0.012
cell cell recognition GO:0009988 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
cell part morphogenesis GO:0032990 246 0.012
organism emergence from protective structure GO:0071684 4 0.012
stem cell division GO:0017145 1 0.012
appendage development GO:0048736 80 0.012
meiotic chromosome segregation GO:0045132 3 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
apoptotic process involved in development GO:1902742 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
spermatid development GO:0007286 2 0.012
regulation of dna replication GO:0006275 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
cellular localization GO:0051641 97 0.012
regulation of hormone secretion GO:0046883 2 0.012
vasculature development GO:0001944 278 0.012
response to vitamin GO:0033273 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
neuroblast proliferation GO:0007405 2 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
positive regulation of cellular process GO:0048522 201 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
homeostatic process GO:0042592 142 0.011
intracellular signal transduction GO:0035556 85 0.011
negative regulation of reproductive process GO:2000242 3 0.011
cellular hormone metabolic process GO:0034754 19 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
somitogenesis GO:0001756 87 0.011
striated muscle tissue development GO:0014706 110 0.011
germ line stem cell maintenance GO:0030718 2 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
retinoid metabolic process GO:0001523 15 0.011
kidney development GO:0001822 92 0.011
skeletal system development GO:0001501 181 0.011
system process GO:0003008 185 0.011
neurotransmitter transport GO:0006836 2 0.011
xenobiotic metabolic process GO:0006805 4 0.011
macromolecule modification GO:0043412 111 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
response to bacterium GO:0009617 58 0.011
response to antibiotic GO:0046677 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
forebrain development GO:0030900 96 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
establishment of localization in cell GO:0051649 77 0.011
pyruvate metabolic process GO:0006090 1 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
myeloid cell homeostasis GO:0002262 56 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
neurotransmitter secretion GO:0007269 2 0.011
positive regulation of chromatin modification GO:1903310 1 0.010
regulation of leukocyte mediated immunity GO:0002703 1 0.010
apical junction assembly GO:0043297 1 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
retina development in camera type eye GO:0060041 146 0.010
neuroblast differentiation GO:0014016 1 0.010
ovulation cycle process GO:0022602 2 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
neuron projection development GO:0031175 180 0.010
regulation of multicellular organismal process GO:0051239 277 0.010
cytokinesis GO:0000910 3 0.010
exocytosis GO:0006887 1 0.010
regulation of cellular component organization GO:0051128 86 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
axon development GO:0061564 166 0.010
fin development GO:0033333 77 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
negative regulation of biosynthetic process GO:0009890 55 0.010

cyp2k6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.074
nervous system disease DOID:863 0 0.027
sensory system disease DOID:0050155 0 0.024
eye and adnexa disease DOID:1492 0 0.024
eye disease DOID:5614 0 0.024
disease of metabolism DOID:0014667 0 0.022
cardiovascular system disease DOID:1287 0 0.018
inherited metabolic disorder DOID:655 0 0.012
musculoskeletal system disease DOID:17 0 0.012