Danio rerio

100 known processes

smad1

MAD homolog 1 (Drosophila)

(Aliases: wu:fb39h09,madh1,fb39h09,MGC92101,wu:fb97e04)

smad1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract morphogenesis GO:0048546 231 0.981
Zebrafish Mouse Fly
digestive tract development GO:0048565 265 0.948
Zebrafish Mouse Fly
digestive system development GO:0055123 289 0.932
Zebrafish Mouse Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.903
Mouse Fly
cell surface receptor signaling pathway GO:0007166 325 0.864
embryonic organ morphogenesis GO:0048562 274 0.765
Zebrafish
gastrulation GO:0007369 208 0.740
Zebrafish Mouse Fly
sensory neuron axon guidance GO:0097374 3 0.719
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.689
Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.687
Fly
oocyte maturation GO:0001556 4 0.672
negative regulation of biological process GO:0048519 304 0.644
signal transduction GO:0007165 455 0.640
chordate embryonic development GO:0043009 271 0.636
positive regulation of cellular component biogenesis GO:0044089 3 0.629
Fly
axon regeneration GO:0031103 14 0.626
locomotion GO:0040011 313 0.599
Zebrafish Fly
response to stress GO:0006950 263 0.598
Mouse
endoderm development GO:0007492 49 0.583
Fly
gamete generation GO:0007276 33 0.575
Zebrafish Mouse Fly
skeletal system development GO:0001501 181 0.565
Mouse
oocyte development GO:0048599 14 0.551
Zebrafish
neuron projection guidance GO:0097485 86 0.540
positive regulation of cell cycle GO:0045787 3 0.531
Worm
embryonic skeletal system morphogenesis GO:0048704 93 0.521
mesenchyme development GO:0060485 127 0.517
developmental growth GO:0048589 166 0.514
Worm Fly
immune system development GO:0002520 191 0.496
axon guidance GO:0007411 86 0.486
cell migration GO:0016477 237 0.484
Zebrafish Fly
otic vesicle morphogenesis GO:0071600 34 0.481
Zebrafish
regulation of metabolic process GO:0019222 359 0.480
nitrogen compound metabolic process GO:0006807 319 0.466
cellular component morphogenesis GO:0032989 336 0.465
embryonic organ development GO:0048568 381 0.459
Zebrafish
regulation of synapse organization GO:0050807 3 0.458
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.455
Zebrafish Mouse Fly
localization of cell GO:0051674 244 0.453
Zebrafish Fly
macromolecule biosynthetic process GO:0009059 227 0.441
tube morphogenesis GO:0035239 349 0.433
Zebrafish Mouse Fly
sexual reproduction GO:0019953 36 0.411
Zebrafish Mouse Fly
reproductive process GO:0022414 40 0.405
Zebrafish Mouse Worm Fly
mesoderm morphogenesis GO:0048332 51 0.403
Mouse
neuron projection regeneration GO:0031102 16 0.392
response to chemical GO:0042221 320 0.390
Mouse Fly
regulation of synapse assembly GO:0051963 3 0.381
Fly
regulation of developmental growth GO:0048638 38 0.375
Worm Fly
mesenchymal cell development GO:0014031 78 0.371
ear morphogenesis GO:0042471 64 0.369
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.367
peptidyl serine phosphorylation GO:0018105 1 0.365
ear development GO:0043583 127 0.364
Zebrafish
axon development GO:0061564 166 0.360
blood vessel development GO:0001568 246 0.358
Zebrafish
protein localization to nucleus GO:0034504 3 0.358
ameboidal type cell migration GO:0001667 143 0.355
Zebrafish
cranial nerve development GO:0021545 42 0.354
cellular ketone metabolic process GO:0042180 11 0.349
cell substrate adhesion GO:0031589 4 0.348
single organism organelle organization GO:1902589 199 0.343
ion transport GO:0006811 114 0.336
negative regulation of cellular process GO:0048523 283 0.330
oligodendrocyte differentiation GO:0048709 23 0.329
somite development GO:0061053 96 0.329
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.328
developmental process involved in reproduction GO:0003006 27 0.325
Zebrafish Worm Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.323
biological adhesion GO:0022610 40 0.318
larval development GO:0002164 2 0.318
protein modification process GO:0036211 100 0.313
Mouse
single organism nuclear import GO:1902593 3 0.296
heart development GO:0007507 313 0.293
Zebrafish Mouse
growth GO:0040007 174 0.288
Mouse Worm Fly
phosphorus metabolic process GO:0006793 109 0.287
Mouse
stem cell differentiation GO:0048863 117 0.287
Fly
synaptic transmission GO:0007268 35 0.281
Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.280
cellular macromolecule biosynthetic process GO:0034645 224 0.277
regulation of peptidase activity GO:0052547 23 0.274
regulation of axonogenesis GO:0050770 32 0.273
sensory organ development GO:0007423 393 0.273
Zebrafish Fly
muscle cell migration GO:0014812 4 0.272
post embryonic organ development GO:0048569 4 0.269
Fly
regulation of gene expression GO:0010468 265 0.269
positive regulation of cellular amine metabolic process GO:0033240 0 0.256
embryonic skeletal system development GO:0048706 97 0.256
liver development GO:0001889 96 0.254
cellular component assembly GO:0022607 170 0.253
Human Fly
regulation of cellular component organization GO:0051128 86 0.253
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.251
membrane organization GO:0061024 21 0.251
inner ear development GO:0048839 126 0.248
Zebrafish
neuron development GO:0048666 262 0.245
regulation of cellular amino acid metabolic process GO:0006521 0 0.242
synaptic growth at neuromuscular junction GO:0051124 2 0.240
Fly
determination of heart left right asymmetry GO:0061371 117 0.238
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.234
Zebrafish
cellular protein metabolic process GO:0044267 129 0.234
Mouse
regulation of reproductive process GO:2000241 4 0.233
Zebrafish
segmentation GO:0035282 97 0.233
Fly
sensory system development GO:0048880 76 0.231
regulation of multicellular organismal development GO:2000026 223 0.230
Zebrafish Mouse Fly
oxoacid metabolic process GO:0043436 31 0.230
head development GO:0060322 303 0.229
Mouse
response to external stimulus GO:0009605 264 0.228
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.222
response to wounding GO:0009611 116 0.218
cell cell signaling GO:0007267 52 0.215
Fly
negative regulation of collateral sprouting GO:0048671 2 0.214
regulation of cellular amine metabolic process GO:0033238 0 0.213
retina development in camera type eye GO:0060041 146 0.212
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.209
gland development GO:0048732 143 0.206
gene expression GO:0010467 252 0.203
regulation of cellular ketone metabolic process GO:0010565 7 0.203
eye morphogenesis GO:0048592 144 0.203
Fly
neural crest cell differentiation GO:0014033 72 0.199
positive regulation of neuron apoptotic process GO:0043525 1 0.199
amine metabolic process GO:0009308 2 0.195
meiotic nuclear division GO:0007126 4 0.194
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.192
cellular amine metabolic process GO:0044106 2 0.191
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.190
transcription dna templated GO:0006351 181 0.185
positive regulation of transport GO:0051050 2 0.183
central nervous system neuron differentiation GO:0021953 74 0.181
cellular aromatic compound metabolic process GO:0006725 295 0.180
heterocycle biosynthetic process GO:0018130 215 0.180
positive regulation of nervous system development GO:0051962 25 0.180
Fly
positive regulation of gene expression GO:0010628 71 0.179
Human Zebrafish Mouse Fly
forebrain cell migration GO:0021885 1 0.179
enzyme linked receptor protein signaling pathway GO:0007167 106 0.178
anterior posterior pattern specification GO:0009952 152 0.177
Fly
metal ion transport GO:0030001 58 0.175
regulation of cell development GO:0060284 100 0.174
Zebrafish
inner ear morphogenesis GO:0042472 63 0.172
Zebrafish
cellular component maintenance GO:0043954 3 0.171
rhombomere boundary formation GO:0021654 10 0.168
nerve development GO:0021675 45 0.168
forebrain development GO:0030900 96 0.167
synapse assembly GO:0007416 9 0.167
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.167
Zebrafish
central nervous system development GO:0007417 387 0.166
Mouse
nuclear transport GO:0051169 4 0.163
multicellular organism reproduction GO:0032504 35 0.161
Zebrafish Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.161
Zebrafish Mouse Fly
cellular component movement GO:0006928 335 0.160
Zebrafish Fly
organelle organization GO:0006996 227 0.160
positive regulation of developmental process GO:0051094 50 0.158
Zebrafish Mouse Worm Fly
myotube differentiation GO:0014902 45 0.156
nucleocytoplasmic transport GO:0006913 4 0.155
cellular response to external stimulus GO:0071496 2 0.154
positive regulation of synapse assembly GO:0051965 1 0.154
Fly
phosphate containing compound metabolic process GO:0006796 108 0.152
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.152
negative regulation of apoptotic process GO:0043066 55 0.151
cellular nitrogen compound metabolic process GO:0034641 290 0.151
immune system process GO:0002376 241 0.150
cytoskeleton organization GO:0007010 96 0.149
posterior lateral line neuromast development GO:0048919 20 0.149
cellular macromolecule localization GO:0070727 21 0.148
branching morphogenesis of a nerve GO:0048755 4 0.148
macromolecular complex subunit organization GO:0043933 74 0.146
Human
lateral line system development GO:0048925 76 0.145
positive regulation of cellular metabolic process GO:0031325 94 0.144
Zebrafish Mouse Fly
muscle organ development GO:0007517 101 0.144
negative regulation of cellular metabolic process GO:0031324 77 0.143
lateral line development GO:0048882 66 0.143
wnt signaling pathway GO:0016055 80 0.141
regulation of multicellular organismal process GO:0051239 277 0.140
Zebrafish Mouse Worm Fly
stem cell development GO:0048864 82 0.139
Fly
dna metabolic process GO:0006259 27 0.138
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.138
cellular component biogenesis GO:0044085 178 0.136
Human Fly
mitotic cell cycle GO:0000278 64 0.136
Worm Fly
chondrocyte development GO:0002063 4 0.136
small molecule metabolic process GO:0044281 77 0.135
regulation of photoreceptor cell differentiation GO:0046532 2 0.134
neural crest cell migration GO:0001755 42 0.133
organonitrogen compound metabolic process GO:1901564 74 0.132
cellular component assembly involved in morphogenesis GO:0010927 107 0.132
forebrain neuron differentiation GO:0021879 14 0.131
embryonic cranial skeleton morphogenesis GO:0048701 90 0.130
branchiomotor neuron axon guidance GO:0021785 1 0.130
system process GO:0003008 185 0.129
protein metabolic process GO:0019538 183 0.128
Mouse
microtubule based process GO:0007017 60 0.128
establishment of mitotic spindle localization GO:0040001 12 0.128
negative regulation of cell communication GO:0010648 96 0.128
convergent extension GO:0060026 118 0.127
Zebrafish
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.127
tissue regeneration GO:0042246 74 0.124
immune response GO:0006955 28 0.124
regulation of proteolysis GO:0030162 24 0.124
adherens junction organization GO:0034332 4 0.123
oocyte differentiation GO:0009994 14 0.122
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.120
peptidyl serine modification GO:0018209 2 0.120
protein localization GO:0008104 40 0.120
stem cell maintenance GO:0019827 4 0.118
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.118
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.117
regeneration GO:0031099 91 0.116
aromatic compound biosynthetic process GO:0019438 217 0.115
extracellular structure organization GO:0043062 27 0.115
positive regulation of rna biosynthetic process GO:1902680 57 0.113
Zebrafish Mouse Fly
positive regulation of oocyte development GO:0060282 1 0.112
Zebrafish
cellular protein modification process GO:0006464 100 0.111
Mouse
regulation of axon extension GO:0030516 24 0.110
neural crest cell development GO:0014032 62 0.109
eye development GO:0001654 277 0.108
Fly
regulation of intracellular protein transport GO:0033157 3 0.107
regulation of signaling GO:0023051 235 0.107
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.106
somitogenesis GO:0001756 87 0.106
nucleic acid metabolic process GO:0090304 244 0.106
brain development GO:0007420 293 0.106
Mouse
connective tissue development GO:0061448 99 0.105
Mouse
protein import GO:0017038 3 0.105
cell motility GO:0048870 244 0.105
Zebrafish Fly
single organism reproductive process GO:0044702 40 0.104
Zebrafish Mouse Fly
camera type eye development GO:0043010 222 0.103
positive regulation of muscle organ development GO:0048636 1 0.101
cell morphogenesis GO:0000902 289 0.100
regulation of neuron projection regeneration GO:0070570 7 0.100
transport GO:0006810 220 0.099
regulation of protein transport GO:0051223 3 0.099
cellular protein catabolic process GO:0044257 4 0.096
notochord development GO:0030903 54 0.096
rhombomere formation GO:0021594 12 0.095
regulation of transcription dna templated GO:0006355 213 0.095
neuromast development GO:0048884 46 0.095
regulation of hydrolase activity GO:0051336 28 0.095
germ cell development GO:0007281 22 0.095
Zebrafish Fly
cellular biosynthetic process GO:0044249 286 0.094
appendage morphogenesis GO:0035107 56 0.094
Fly
apoptotic process GO:0006915 116 0.091
heart morphogenesis GO:0003007 156 0.090
Zebrafish
negative regulation of signaling GO:0023057 96 0.090
hard palate development GO:0060022 4 0.090
Zebrafish
skeletal muscle tissue development GO:0007519 67 0.090
chemotaxis GO:0006935 104 0.088
Fly
organelle localization GO:0051640 49 0.088
developmental growth involved in morphogenesis GO:0060560 86 0.088
neuromuscular synaptic transmission GO:0007274 2 0.087
negative regulation of neuron projection regeneration GO:0070571 4 0.087
camera type eye morphogenesis GO:0048593 108 0.086
regulation of biosynthetic process GO:0009889 250 0.086
wound healing GO:0042060 90 0.086
post anal tail morphogenesis GO:0036342 19 0.085
Zebrafish
regulation of cell differentiation GO:0045595 142 0.085
Zebrafish Mouse Fly
regulation of embryonic development GO:0045995 47 0.084
Zebrafish
epithelial cell morphogenesis GO:0003382 2 0.084
taxis GO:0042330 109 0.084
Fly
ossification GO:0001503 23 0.083
Mouse
negative regulation of catalytic activity GO:0043086 21 0.083
multicellular organism growth GO:0035264 4 0.082
Worm
cytokine mediated signaling pathway GO:0019221 7 0.082
mesoderm development GO:0007498 88 0.079
Mouse
biosynthetic process GO:0009058 294 0.078
regulation of macromolecule biosynthetic process GO:0010556 225 0.078
regionalization GO:0003002 274 0.078
regulation of biological quality GO:0065008 263 0.077
Mouse Fly
negative regulation of protein phosphorylation GO:0001933 4 0.077
transcription from rna polymerase ii promoter GO:0006366 80 0.076
negative regulation of metabolic process GO:0009892 86 0.075
primary neural tube formation GO:0014020 1 0.075
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.075
axonogenesis GO:0007409 152 0.075
rhombomere morphogenesis GO:0021593 17 0.075
somatic muscle development GO:0007525 4 0.075
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.074
nucleobase containing compound metabolic process GO:0006139 274 0.074
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.074
female sex differentiation GO:0046660 4 0.074
collateral sprouting GO:0048668 9 0.073
skin development GO:0043588 54 0.073
negative regulation of phosphate metabolic process GO:0045936 13 0.073
response to growth factor GO:0070848 39 0.072
Mouse Fly
single organism transport GO:0044765 206 0.072
negative regulation of signal transduction GO:0009968 94 0.072
phosphorylation GO:0016310 69 0.072
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.071
negative regulation of map kinase activity GO:0043407 2 0.071
blood vessel morphogenesis GO:0048514 216 0.071
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.071
regulation of wnt signaling pathway GO:0030111 53 0.070
blood circulation GO:0008015 87 0.070
regulation of multicellular organism growth GO:0040014 4 0.070
Worm
regulation of metal ion transport GO:0010959 4 0.070
oogenesis GO:0048477 14 0.070
Zebrafish Fly
formation of primary germ layer GO:0001704 62 0.070
Mouse Fly
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.070
protein import into nucleus GO:0006606 3 0.069
regulation of response to stimulus GO:0048583 269 0.069
Zebrafish
cell part morphogenesis GO:0032990 246 0.069
negative regulation of mapk cascade GO:0043409 4 0.068
regulation of cytoplasmic transport GO:1903649 4 0.068
establishment of protein localization to organelle GO:0072594 4 0.068
regulation of cell communication GO:0010646 232 0.068
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.068
Human Zebrafish Mouse Fly
specification of axis polarity GO:0065001 4 0.068
rna metabolic process GO:0016070 219 0.067
adenohypophysis development GO:0021984 15 0.067
angiogenesis GO:0001525 158 0.067
cellular response to growth factor stimulus GO:0071363 39 0.067
Mouse Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.067
positive regulation of neuron death GO:1901216 1 0.066
ectodermal placode development GO:0071696 37 0.066
Zebrafish
regulation of programmed cell death GO:0043067 101 0.065
neuron projection morphogenesis GO:0048812 161 0.065
negative regulation of response to stimulus GO:0048585 104 0.065
hindbrain development GO:0030902 91 0.063
Mouse
facial nerve development GO:0021561 3 0.062
regulation of mitotic cell cycle GO:0007346 25 0.062
Worm Fly
muscle cell development GO:0055001 115 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.061
regulation of rna metabolic process GO:0051252 224 0.060
single organism cellular localization GO:1902580 46 0.060
mitotic cell cycle process GO:1903047 48 0.060
Fly
cellular amino acid metabolic process GO:0006520 7 0.059
positive regulation of metabolic process GO:0009893 108 0.059
Human Zebrafish Mouse Fly
positive regulation of biological process GO:0048518 253 0.059
Human Zebrafish Mouse Worm Fly
regulation of synaptic plasticity GO:0048167 1 0.058
organic cyclic compound biosynthetic process GO:1901362 223 0.058
phagocytosis GO:0006909 3 0.058
positive regulation of transcription dna templated GO:0045893 57 0.058
Zebrafish Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.058
Zebrafish Mouse Fly
regulation of cell cycle process GO:0010564 20 0.058
Fly
cell migration involved in gastrulation GO:0042074 79 0.058
Zebrafish
response to drug GO:0042493 3 0.057
negative regulation of catabolic process GO:0009895 3 0.057
regulation of binding GO:0051098 3 0.057
multicellular organismal homeostasis GO:0048871 29 0.056
cellular protein localization GO:0034613 20 0.056
positive regulation of biosynthetic process GO:0009891 68 0.056
Zebrafish Mouse Fly
generation of neurons GO:0048699 385 0.055
microtubule cytoskeleton organization GO:0000226 33 0.055
negative regulation of protein kinase activity GO:0006469 4 0.055
mapk cascade GO:0000165 18 0.054
Mouse
regulation of axon regeneration GO:0048679 7 0.054
mechanoreceptor differentiation GO:0042490 37 0.054
neurotransmitter transport GO:0006836 2 0.053
multicellular organismal reproductive process GO:0048609 35 0.052
Zebrafish Mouse Fly
negative regulation of axon regeneration GO:0048681 4 0.052
nucleoside monophosphate catabolic process GO:0009125 4 0.052
positive regulation of striated muscle tissue development GO:0045844 1 0.052
cell projection organization GO:0030030 284 0.051
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
semicircular canal morphogenesis GO:0048752 18 0.051
phagocytosis engulfment GO:0006911 1 0.050
pronephros development GO:0048793 69 0.050
phenol containing compound metabolic process GO:0018958 5 0.050
cellular response to stress GO:0033554 62 0.049
extracellular matrix organization GO:0030198 27 0.049
cardiogenic plate morphogenesis GO:0003142 1 0.049
divalent metal ion transport GO:0070838 20 0.048
macromolecule modification GO:0043412 111 0.048
Mouse
erk1 and erk2 cascade GO:0070371 4 0.048
dorsal convergence GO:0060030 14 0.048
Zebrafish
mechanosensory lateral line system development GO:0048881 49 0.048
motor neuron axon guidance GO:0008045 23 0.048
heart jogging GO:0003146 40 0.048
Zebrafish
neuromuscular junction development GO:0007528 9 0.047
Fly
glial cell differentiation GO:0010001 42 0.047
muscle tissue development GO:0060537 110 0.047
Mouse
regulation of skeletal muscle tissue development GO:0048641 4 0.047
mesoderm formation GO:0001707 43 0.047
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.047
Zebrafish Fly
retinal ganglion cell axon guidance GO:0031290 35 0.046
synapse organization GO:0050808 21 0.046
Fly
cell cell recognition GO:0009988 1 0.046
nuclear migration GO:0007097 3 0.046
hepaticobiliary system development GO:0061008 98 0.046
embryonic digestive tract morphogenesis GO:0048557 3 0.046
embryonic heart tube development GO:0035050 133 0.046
Zebrafish
establishment of localization GO:0051234 244 0.046
muscle fiber development GO:0048747 52 0.045
regulation of rna biosynthetic process GO:2001141 213 0.045
ectodermal placode formation GO:0060788 26 0.045
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.045
Zebrafish Mouse Fly
regulation of nervous system development GO:0051960 90 0.044
Fly
organic cyclic compound metabolic process GO:1901360 301 0.044
negative regulation of reproductive process GO:2000242 3 0.044
epidermis development GO:0008544 48 0.044
innate immune response GO:0045087 13 0.044
embryonic skeletal joint morphogenesis GO:0060272 3 0.044
blood vessel endothelial cell migration GO:0043534 18 0.044
negative regulation of programmed cell death GO:0043069 58 0.044
positive regulation of cell proliferation GO:0008284 15 0.043
regulation of protein ubiquitination GO:0031396 3 0.043
epithelial tube morphogenesis GO:0060562 148 0.043
Zebrafish Fly
aging GO:0007568 2 0.043
ribonucleoside monophosphate catabolic process GO:0009158 4 0.043
regulation of collateral sprouting in absence of injury GO:0048696 4 0.042
myeloid cell development GO:0061515 32 0.042
energy reserve metabolic process GO:0006112 2 0.042
response to xenobiotic stimulus GO:0009410 45 0.042
regulation of dna replication GO:0006275 3 0.042
regulation of dna templated transcription in response to stress GO:0043620 0 0.042
anatomical structure arrangement GO:0048532 2 0.042
lateral mesoderm development GO:0048368 23 0.042
negative regulation of nucleic acid templated transcription GO:1903507 45 0.041
cell death GO:0008219 121 0.041
neuron differentiation GO:0030182 353 0.041
regulation of meiotic cell cycle GO:0051445 1 0.041
Worm
neurological system process GO:0050877 62 0.041
membrane fusion GO:0061025 2 0.040
fin development GO:0033333 77 0.040
regulation of nucleocytoplasmic transport GO:0046822 2 0.040
axonogenesis involved in innervation GO:0060385 1 0.040
centrosome organization GO:0051297 1 0.040
muscle structure development GO:0061061 196 0.040
regulation of membrane potential GO:0042391 23 0.040
regulation of striated muscle tissue development GO:0016202 6 0.039
regulation of protein localization to nucleus GO:1900180 2 0.039
purine ribonucleotide metabolic process GO:0009150 27 0.038
regulation of heart morphogenesis GO:2000826 17 0.038
Zebrafish
diencephalon development GO:0021536 58 0.038
establishment of organelle localization GO:0051656 45 0.038
cell projection morphogenesis GO:0048858 244 0.038
regulation of collateral sprouting GO:0048670 7 0.038
sensory organ morphogenesis GO:0090596 200 0.038
Zebrafish Fly
organelle assembly GO:0070925 110 0.038
hair cell differentiation GO:0035315 32 0.037
establishment of localization in cell GO:0051649 77 0.037
nuclear import GO:0051170 3 0.037
negative regulation of cell death GO:0060548 60 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.037
Zebrafish Mouse Fly
tissue migration GO:0090130 37 0.037
protein targeting to nucleus GO:0044744 3 0.036
regulation of heart growth GO:0060420 2 0.036
regulation of phosphorus metabolic process GO:0051174 43 0.036
skeletal muscle organ development GO:0060538 78 0.036
ectodermal placode morphogenesis GO:0071697 32 0.035
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.035
ion homeostasis GO:0050801 41 0.035
cellular response to chemical stimulus GO:0070887 157 0.035
Mouse Fly
innervation GO:0060384 3 0.035
purine nucleoside monophosphate catabolic process GO:0009128 4 0.035
female gonad development GO:0008585 4 0.035
peripheral nervous system development GO:0007422 55 0.035
positive regulation of cellular component organization GO:0051130 13 0.035
Fly
positive regulation of reproductive process GO:2000243 2 0.035
Zebrafish
regulation of transmembrane transport GO:0034762 18 0.035
mitotic g2 dna damage checkpoint GO:0007095 3 0.035
response to mechanical stimulus GO:0009612 24 0.035
female gamete generation GO:0007292 14 0.034
Zebrafish Fly
negative regulation of axon extension GO:0030517 7 0.034
endocardial cushion formation GO:0003272 2 0.034
regulation of localization GO:0032879 104 0.034
positive regulation of cellular process GO:0048522 201 0.034
Zebrafish Mouse Worm Fly
body morphogenesis GO:0010171 16 0.034
calcium ion transport GO:0006816 18 0.034
embryonic digestive tract development GO:0048566 4 0.034
spindle localization GO:0051653 12 0.034
neuron recognition GO:0008038 18 0.034
meiotic chromosome segregation GO:0045132 3 0.034
positive regulation of apoptotic process GO:0043065 29 0.034
regulation of cellular metabolic process GO:0031323 320 0.034
response to abiotic stimulus GO:0009628 122 0.034
endodermal cell differentiation GO:0035987 19 0.034
Fly
secondary metabolic process GO:0019748 3 0.034
lymph vessel development GO:0001945 27 0.033
programmed cell death GO:0012501 119 0.033
regulation of response to cytokine stimulus GO:0060759 3 0.033
single organism biosynthetic process GO:0044711 71 0.033
negative regulation of phosphorus metabolic process GO:0010563 13 0.033
establishment of cell polarity GO:0030010 18 0.033
regulation of stem cell differentiation GO:2000736 4 0.033
septum transversum development GO:0003343 4 0.033
organic substance biosynthetic process GO:1901576 289 0.033
homeostatic process GO:0042592 142 0.033
Mouse
protein phosphorylation GO:0006468 47 0.032
Mouse
collateral sprouting of intact axon in response to injury GO:0048673 2 0.032
negative regulation of gene expression GO:0010629 65 0.032
response to alkaloid GO:0043279 2 0.032
mesodermal cell fate specification GO:0007501 12 0.032
membrane invagination GO:0010324 1 0.032
neural retina development GO:0003407 49 0.032
cellular localization GO:0051641 97 0.032
extrinsic apoptotic signaling pathway GO:0097191 3 0.032
digestive tract mesoderm development GO:0007502 1 0.032
regulation of cardiac muscle tissue development GO:0055024 1 0.031
regulation of apoptotic process GO:0042981 98 0.031
cell proliferation GO:0008283 80 0.031
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
positive regulation of catabolic process GO:0009896 4 0.031
regulation of oocyte development GO:0060281 3 0.031
Zebrafish
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.031
embryonic heart tube morphogenesis GO:0003143 108 0.031
Zebrafish

smad1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.710
cancer DOID:162 0 0.105
disease of cellular proliferation DOID:14566 0 0.105
organ system cancer DOID:0050686 0 0.105
nervous system disease DOID:863 0 0.036