Danio rerio

20 known processes

hmgb1a

high-mobility group box 1a

(Aliases: xx:tdsubc_1a5,zgc:56110,hmgb1,zgc:77104,ik:tdsubc_1a5,wu:fb23c02)

hmgb1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phagocytosis GO:0006909 3 0.880
nucleobase containing compound metabolic process GO:0006139 274 0.808
organic cyclic compound metabolic process GO:1901360 301 0.783
regulation of macromolecule metabolic process GO:0060255 317 0.737
nucleic acid templated transcription GO:0097659 181 0.712
aromatic compound biosynthetic process GO:0019438 217 0.709
nucleobase containing compound biosynthetic process GO:0034654 205 0.699
cellular macromolecule biosynthetic process GO:0034645 224 0.698
positive regulation of cellular process GO:0048522 201 0.698
cellular nitrogen compound biosynthetic process GO:0044271 218 0.688
cellular macromolecule metabolic process GO:0044260 391 0.650
nucleic acid metabolic process GO:0090304 244 0.645
regulation of transcription dna templated GO:0006355 213 0.644
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.639
gene expression GO:0010467 252 0.606
regulation of cellular biosynthetic process GO:0031326 245 0.605
regulation of macromolecule biosynthetic process GO:0010556 225 0.591
regulation of nitrogen compound metabolic process GO:0051171 251 0.578
regulation of cellular metabolic process GO:0031323 320 0.569
positive regulation of myeloid cell differentiation GO:0045639 2 0.562
negative regulation of biological process GO:0048519 304 0.560
organic cyclic compound biosynthetic process GO:1901362 223 0.546
cellular aromatic compound metabolic process GO:0006725 295 0.540
negative regulation of cellular process GO:0048523 283 0.539
single organism metabolic process GO:0044710 217 0.519
macromolecule biosynthetic process GO:0009059 227 0.515
cellular component movement GO:0006928 335 0.513
positive regulation of biological process GO:0048518 253 0.511
regulation of nucleic acid templated transcription GO:1903506 213 0.508
regulation of biosynthetic process GO:0009889 250 0.500
organic substance biosynthetic process GO:1901576 289 0.497
cellular nitrogen compound metabolic process GO:0034641 290 0.488
cellular biosynthetic process GO:0044249 286 0.481
response to steroid hormone GO:0048545 35 0.436
rna biosynthetic process GO:0032774 181 0.433
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.418
central nervous system development GO:0007417 387 0.418
purine nucleotide biosynthetic process GO:0006164 20 0.397
startle response GO:0001964 4 0.383
head development GO:0060322 303 0.381
organelle organization GO:0006996 227 0.381
negative regulation of gene expression GO:0010629 65 0.377
regulation of rna biosynthetic process GO:2001141 213 0.363
heterocycle biosynthetic process GO:0018130 215 0.353
cell migration GO:0016477 237 0.352
regulation of gene expression GO:0010468 265 0.351
cell motility GO:0048870 244 0.345
regulation of binding GO:0051098 3 0.337
biosynthetic process GO:0009058 294 0.329
negative regulation of transcription dna templated GO:0045892 45 0.314
specification of symmetry GO:0009799 204 0.309
generation of neurons GO:0048699 385 0.293
rna metabolic process GO:0016070 219 0.289
positive regulation of macromolecule metabolic process GO:0010604 93 0.286
positive regulation of cellular metabolic process GO:0031325 94 0.285
multicellular organism reproduction GO:0032504 35 0.272
regulation of biological quality GO:0065008 263 0.267
response to chemical GO:0042221 320 0.264
central nervous system neuron differentiation GO:0021953 74 0.260
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.256
positive regulation of gene expression GO:0010628 71 0.246
vasculature development GO:0001944 278 0.243
response to organic substance GO:0010033 153 0.243
cell surface receptor signaling pathway GO:0007166 325 0.242
regulation of signaling GO:0023051 235 0.235
response to external stimulus GO:0009605 264 0.235
apoptotic process GO:0006915 116 0.233
nitrogen compound metabolic process GO:0006807 319 0.231
neuron neuron synaptic transmission GO:0007270 1 0.230
positive regulation of cellular biosynthetic process GO:0031328 68 0.226
regulation of neural precursor cell proliferation GO:2000177 3 0.220
localization of cell GO:0051674 244 0.218
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.218
cyclic nucleotide metabolic process GO:0009187 18 0.217
regulation of signal transduction GO:0009966 225 0.212
ameboidal type cell migration GO:0001667 143 0.209
positive regulation of metabolic process GO:0009893 108 0.207
heterocycle metabolic process GO:0046483 290 0.199
phosphate containing compound metabolic process GO:0006796 108 0.199
negative regulation of macromolecule metabolic process GO:0010605 76 0.198
regulation of developmental process GO:0050793 247 0.191
eye development GO:0001654 277 0.190
regulation of proteolysis GO:0030162 24 0.189
immune system process GO:0002376 241 0.189
locomotion GO:0040011 313 0.187
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.183
stem cell maintenance GO:0019827 4 0.180
axonogenesis GO:0007409 152 0.177
negative regulation of protein complex assembly GO:0031333 1 0.175
anterior posterior pattern specification GO:0009952 152 0.175
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.174
cell proliferation GO:0008283 80 0.171
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.171
positive regulation of rna biosynthetic process GO:1902680 57 0.171
regulation of multicellular organismal process GO:0051239 277 0.166
protein metabolic process GO:0019538 183 0.166
myeloid cell differentiation GO:0030099 86 0.165
response to stress GO:0006950 263 0.163
limbic system development GO:0021761 16 0.162
hematopoietic or lymphoid organ development GO:0048534 191 0.162
organelle fission GO:0048285 23 0.161
spermatid differentiation GO:0048515 2 0.157
signal transduction GO:0007165 455 0.153
transcription dna templated GO:0006351 181 0.151
neuron projection guidance GO:0097485 86 0.150
positive regulation of nucleic acid templated transcription GO:1903508 57 0.149
cellular component morphogenesis GO:0032989 336 0.148
positive regulation of cellular catabolic process GO:0031331 3 0.142
somite development GO:0061053 96 0.140
positive regulation of carbohydrate metabolic process GO:0045913 1 0.137
positive regulation of molecular function GO:0044093 33 0.134
single organism reproductive process GO:0044702 40 0.134
small molecule metabolic process GO:0044281 77 0.129
regulation of rna metabolic process GO:0051252 224 0.129
phosphorus metabolic process GO:0006793 109 0.129
regulation of metabolic process GO:0019222 359 0.128
regionalization GO:0003002 274 0.128
regulation of mrna splicing via spliceosome GO:0048024 3 0.123
somatic cell dna recombination GO:0016444 1 0.122
cellular protein catabolic process GO:0044257 4 0.122
mesenchymal cell differentiation GO:0048762 87 0.121
blood vessel development GO:0001568 246 0.120
regulation of response to stimulus GO:0048583 269 0.120
spermatid development GO:0007286 2 0.119
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.119
regulation of multicellular organismal development GO:2000026 223 0.118
cell morphogenesis involved in differentiation GO:0000904 195 0.117
stem cell development GO:0048864 82 0.116
positive regulation of rna metabolic process GO:0051254 59 0.114
brain development GO:0007420 293 0.113
regulation of molecular function GO:0065009 70 0.111
ribose phosphate biosynthetic process GO:0046390 20 0.111
positive regulation of transport GO:0051050 2 0.108
transcription from rna polymerase ii promoter GO:0006366 80 0.108
negative regulation of cellular biosynthetic process GO:0031327 55 0.106
lateral inhibition GO:0046331 1 0.106
proteasomal protein catabolic process GO:0010498 2 0.105
negative regulation of response to stimulus GO:0048585 104 0.104
negative regulation of metabolic process GO:0009892 86 0.101
positive regulation of apoptotic process GO:0043065 29 0.101
negative regulation of rna biosynthetic process GO:1902679 45 0.100
convergent extension involved in organogenesis GO:0060029 10 0.099
epithelial cell differentiation GO:0030855 116 0.098
aorta development GO:0035904 4 0.097
angiogenesis GO:0001525 158 0.097
aging GO:0007568 2 0.096
regulation of localization GO:0032879 104 0.094
positive regulation of response to stimulus GO:0048584 80 0.094
dopaminergic neuron differentiation GO:0071542 14 0.091
regulation of mrna processing GO:0050684 3 0.090
blood vessel morphogenesis GO:0048514 216 0.089
hormone transport GO:0009914 2 0.089
modification dependent macromolecule catabolic process GO:0043632 3 0.088
regulation of protein metabolic process GO:0051246 56 0.086
multi organism process GO:0051704 134 0.085
mitotic nuclear division GO:0007067 18 0.084
somitogenesis GO:0001756 87 0.082
chemotaxis GO:0006935 104 0.080
response to hormone GO:0009725 48 0.080
negative regulation of nucleic acid templated transcription GO:1903507 45 0.079
ubiquitin dependent protein catabolic process GO:0006511 3 0.077
negative regulation of cellular component organization GO:0051129 16 0.076
reproduction GO:0000003 40 0.076
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.075
regulation of cysteine type endopeptidase activity GO:2000116 21 0.075
cyclic nucleotide biosynthetic process GO:0009190 18 0.074
positive regulation of transcription dna templated GO:0045893 57 0.072
neuron projection morphogenesis GO:0048812 161 0.072
glucose homeostasis GO:0042593 1 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.071
regulation of primary metabolic process GO:0080090 311 0.071
regulation of phosphorus metabolic process GO:0051174 43 0.070
cell cycle GO:0007049 93 0.070
positive regulation of catabolic process GO:0009896 4 0.069
cell morphogenesis GO:0000902 289 0.069
somatic muscle development GO:0007525 4 0.068
response to corticosteroid GO:0031960 1 0.067
mesenchyme development GO:0060485 127 0.066
negative regulation of rna metabolic process GO:0051253 48 0.066
response to oxygen containing compound GO:1901700 55 0.066
response to glucocorticoid GO:0051384 1 0.065
brain morphogenesis GO:0048854 18 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.064
neuron differentiation GO:0030182 353 0.064
lipid storage GO:0019915 1 0.064
gamete generation GO:0007276 33 0.063
organonitrogen compound metabolic process GO:1901564 74 0.063
nucleotide metabolic process GO:0009117 28 0.063
reproductive process GO:0022414 40 0.063
stem cell proliferation GO:0072089 4 0.061
maintenance of location GO:0051235 4 0.060
tube morphogenesis GO:0035239 349 0.060
negative regulation of cell communication GO:0010648 96 0.060
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.060
gastrulation GO:0007369 208 0.059
peptidyl serine phosphorylation GO:0018105 1 0.059
negative regulation of leukocyte differentiation GO:1902106 1 0.058
regulation of myeloid cell differentiation GO:0045637 8 0.058
regulation of cell differentiation GO:0045595 142 0.058
sensory system development GO:0048880 76 0.058
regulation of cell death GO:0010941 103 0.057
alternative mrna splicing via spliceosome GO:0000380 1 0.056
positive regulation of cell cycle GO:0045787 3 0.056
regulation of endocytosis GO:0030100 7 0.056
modification dependent protein catabolic process GO:0019941 3 0.056
regulation of protein complex assembly GO:0043254 3 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.055
regulation of protein binding GO:0043393 3 0.055
regulation of cell cycle GO:0051726 52 0.054
hemopoiesis GO:0030097 183 0.054
heart development GO:0007507 313 0.053
rna stabilization GO:0043489 4 0.053
protein phosphorylation GO:0006468 47 0.052
dorsal ventral pattern formation GO:0009953 125 0.052
behavior GO:0007610 74 0.052
cellular carbohydrate metabolic process GO:0044262 4 0.052
positive regulation of striated muscle tissue development GO:0045844 1 0.052
negative regulation of signal transduction GO:0009968 94 0.051
regulation of catalytic activity GO:0050790 55 0.051
ribonucleotide biosynthetic process GO:0009260 20 0.051
developmental process involved in reproduction GO:0003006 27 0.051
defense response GO:0006952 47 0.050
cellular protein metabolic process GO:0044267 129 0.050
urogenital system development GO:0001655 97 0.050
negative regulation of cellular metabolic process GO:0031324 77 0.050
larval development GO:0002164 2 0.049
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.049
cellular catabolic process GO:0044248 27 0.049
regulation of cellular protein metabolic process GO:0032268 52 0.048
response to biotic stimulus GO:0009607 97 0.047
neuroblast proliferation GO:0007405 2 0.047
regulation of immune system process GO:0002682 34 0.046
cellular component biogenesis GO:0044085 178 0.046
carboxylic acid metabolic process GO:0019752 22 0.045
regulation of intracellular protein transport GO:0033157 3 0.045
negative regulation of signaling GO:0023057 96 0.045
cell cycle process GO:0022402 53 0.044
heart looping GO:0001947 94 0.044
lipid homeostasis GO:0055088 3 0.044
wnt signaling pathway GO:0016055 80 0.044
regulation of cellular protein catabolic process GO:1903362 1 0.044
positive regulation of immune effector process GO:0002699 3 0.044
meiotic nuclear division GO:0007126 4 0.043
nucleotide biosynthetic process GO:0009165 21 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.043
protein stabilization GO:0050821 2 0.043
chemical homeostasis GO:0048878 49 0.043
cognition GO:0050890 1 0.042
gtp metabolic process GO:0046039 4 0.042
regulation of epithelial cell proliferation GO:0050678 3 0.042
regulation of translational initiation GO:0006446 1 0.041
neuron development GO:0048666 262 0.040
macromolecule localization GO:0033036 54 0.040
gene silencing GO:0016458 4 0.040
neurotransmitter secretion GO:0007269 2 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.039
proteolysis GO:0006508 38 0.039
mitotic cell cycle GO:0000278 64 0.039
regulation of organ growth GO:0046620 3 0.039
protein modification process GO:0036211 100 0.039
regulation of nervous system development GO:0051960 90 0.039
nuclear transport GO:0051169 4 0.037
purine containing compound biosynthetic process GO:0072522 20 0.037
positive regulation of programmed cell death GO:0043068 29 0.037
single organism transport GO:0044765 206 0.037
translational initiation GO:0006413 3 0.037
negative regulation of biosynthetic process GO:0009890 55 0.037
regulation of ion transmembrane transporter activity GO:0032412 2 0.036
neural crest cell differentiation GO:0014033 72 0.036
regulation of locomotion GO:0040012 55 0.036
death GO:0016265 121 0.036
phosphorylation GO:0016310 69 0.036
sensory organ development GO:0007423 393 0.036
embryonic limb morphogenesis GO:0030326 2 0.035
male gamete generation GO:0048232 7 0.035
taxis GO:0042330 109 0.035
response to organic cyclic compound GO:0014070 51 0.035
regulation of cell communication GO:0010646 232 0.034
system process GO:0003008 185 0.034
regulation of cell division GO:0051302 12 0.034
negative regulation of mitosis GO:0045839 3 0.034
cellular protein modification process GO:0006464 100 0.034
peripheral nervous system development GO:0007422 55 0.034
muscle structure development GO:0061061 196 0.034
regulation of apoptotic process GO:0042981 98 0.033
negative regulation of developmental process GO:0051093 65 0.033
connective tissue development GO:0061448 99 0.033
regulation of hydrolase activity GO:0051336 28 0.033
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
positive regulation of biosynthetic process GO:0009891 68 0.033
artery morphogenesis GO:0048844 14 0.033
cell migration involved in gastrulation GO:0042074 79 0.033
neuron projection development GO:0031175 180 0.033
neural crest formation GO:0014029 14 0.033
single organism localization GO:1902578 225 0.032
nucleoside phosphate biosynthetic process GO:1901293 21 0.032
enzyme linked receptor protein signaling pathway GO:0007167 106 0.032
morphogenesis of an epithelium GO:0002009 333 0.032
photoreceptor cell fate commitment GO:0046552 1 0.032
epithelial to mesenchymal transition GO:0001837 21 0.032
embryonic heart tube development GO:0035050 133 0.032
skeletal muscle organ development GO:0060538 78 0.032
cellular response to organic substance GO:0071310 105 0.031
locomotor rhythm GO:0045475 3 0.031
rna transport GO:0050658 2 0.031
positive regulation of muscle tissue development GO:1901863 1 0.031
regulation of canonical wnt signaling pathway GO:0060828 34 0.031
regulation of programmed cell death GO:0043067 101 0.031
stem cell differentiation GO:0048863 117 0.031
forebrain development GO:0030900 96 0.030
aorta morphogenesis GO:0035909 3 0.030
axon guidance GO:0007411 86 0.029
regulation of reproductive process GO:2000241 4 0.029
regulation of synapse assembly GO:0051963 3 0.029
oxidation reduction process GO:0055114 41 0.029
embryonic cranial skeleton morphogenesis GO:0048701 90 0.029
regulation of transporter activity GO:0032409 2 0.029
diencephalon development GO:0021536 58 0.028
positive regulation of developmental process GO:0051094 50 0.028
nuclear export GO:0051168 1 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.028
spermatogenesis GO:0007283 7 0.028
transport GO:0006810 220 0.028
digestive tract development GO:0048565 265 0.028
regulation of mitotic cell cycle GO:0007346 25 0.028
rna localization GO:0006403 4 0.028
chordate embryonic development GO:0043009 271 0.028
energy reserve metabolic process GO:0006112 2 0.028
negative regulation of cell development GO:0010721 26 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
response to other organism GO:0051707 97 0.027
calcium ion transmembrane transport GO:0070588 13 0.027
establishment of rna localization GO:0051236 3 0.027
positive regulation of cell communication GO:0010647 56 0.027
organelle assembly GO:0070925 110 0.027
mesenchymal cell development GO:0014031 78 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
embryonic pectoral fin morphogenesis GO:0035118 24 0.027
response to endogenous stimulus GO:0009719 83 0.026
axon development GO:0061564 166 0.026
hindbrain development GO:0030902 91 0.026
cell projection organization GO:0030030 284 0.026
regulation of synaptic plasticity GO:0048167 1 0.026
regulation of synapse organization GO:0050807 3 0.026
negative regulation of neuron differentiation GO:0045665 10 0.025
embryonic organ development GO:0048568 381 0.025
nucleobase containing small molecule metabolic process GO:0055086 32 0.025
3 utr mediated mrna stabilization GO:0070935 3 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
cell part morphogenesis GO:0032990 246 0.025
regulation of calcium ion dependent exocytosis GO:0017158 1 0.025
cellular response to chemical stimulus GO:0070887 157 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
positive regulation of multi organism process GO:0043902 3 0.024
dna templated transcription initiation GO:0006352 1 0.024
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.024
hormone secretion GO:0046879 2 0.024
digestive tract morphogenesis GO:0048546 231 0.024
positive regulation of cell death GO:0010942 29 0.024
regulation of wnt signaling pathway GO:0030111 53 0.024
homeostatic process GO:0042592 142 0.024
single organism carbohydrate metabolic process GO:0044723 12 0.023
ovulation cycle GO:0042698 2 0.023
rhythmic process GO:0048511 21 0.023
positive regulation of endopeptidase activity GO:0010950 10 0.023
neural tube patterning GO:0021532 33 0.023
mitotic cell cycle embryonic GO:0045448 2 0.023
neural crest cell development GO:0014032 62 0.022
cellular response to biotic stimulus GO:0071216 3 0.022
sensory perception of chemical stimulus GO:0007606 3 0.022
intracellular signal transduction GO:0035556 85 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
response to alkaloid GO:0043279 2 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
regulation of protein ubiquitination GO:0031396 3 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.021
regulation of vesicle mediated transport GO:0060627 9 0.021
gastrulation with mouth forming second GO:0001702 44 0.021
multicellular organismal reproductive process GO:0048609 35 0.021
eye morphogenesis GO:0048592 144 0.021
cellular localization GO:0051641 97 0.021
negative regulation of cell differentiation GO:0045596 46 0.021
response to lipid GO:0033993 60 0.021
positive regulation of neuron apoptotic process GO:0043525 1 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
regulation of phosphate metabolic process GO:0019220 43 0.020
female gonad development GO:0008585 4 0.020
response to uv GO:0009411 3 0.020
regulation of stem cell proliferation GO:0072091 2 0.020
single organism biosynthetic process GO:0044711 71 0.020
neuron fate determination GO:0048664 2 0.020
sprouting angiogenesis GO:0002040 53 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.019
macromolecule modification GO:0043412 111 0.019
exocrine pancreas development GO:0031017 28 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
cyclic purine nucleotide metabolic process GO:0052652 18 0.019
developmental maturation GO:0021700 34 0.019
striated muscle tissue development GO:0014706 110 0.019
dna metabolic process GO:0006259 27 0.019
response to nutrient GO:0007584 3 0.019
midbrain development GO:0030901 28 0.019
regulation of cell proliferation GO:0042127 37 0.019
regulation of neurological system process GO:0031644 2 0.018
organic substance catabolic process GO:1901575 28 0.018
cell projection morphogenesis GO:0048858 244 0.018
mrna stabilization GO:0048255 4 0.018
determination of bilateral symmetry GO:0009855 204 0.018
inorganic cation transmembrane transport GO:0098662 50 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
skeletal muscle tissue development GO:0007519 67 0.018
immune system development GO:0002520 191 0.018
leukocyte activation GO:0045321 12 0.018
regulation of cell activation GO:0050865 1 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
negative regulation of nervous system development GO:0051961 22 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
negative regulation of nuclear division GO:0051784 3 0.017
muscle organ development GO:0007517 101 0.017
female meiotic division GO:0007143 2 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
cell maturation GO:0048469 23 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of cellular component biogenesis GO:0044087 12 0.017
regulation of myelination GO:0031641 1 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
central nervous system neuron development GO:0021954 29 0.017
multicellular organism growth GO:0035264 4 0.017
cellular response to external stimulus GO:0071496 2 0.017
determination of left right symmetry GO:0007368 179 0.017
stem cell division GO:0017145 1 0.017
response to nutrient levels GO:0031667 10 0.016
developmental programmed cell death GO:0010623 4 0.016
cellular response to decreased oxygen levels GO:0036294 1 0.016
regulation of endopeptidase activity GO:0052548 23 0.016
retinal cell programmed cell death GO:0046666 2 0.016
regulation of smoothened signaling pathway GO:0008589 18 0.016
gabaergic neuron differentiation GO:0097154 2 0.016
regulation of oligodendrocyte differentiation GO:0048713 1 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
organophosphate metabolic process GO:0019637 37 0.016
synapse assembly GO:0007416 9 0.016
positive regulation of catalytic activity GO:0043085 25 0.016
lateral line development GO:0048882 66 0.016
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
positive regulation of protein metabolic process GO:0051247 23 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
neurotransmitter transport GO:0006836 2 0.015
heart morphogenesis GO:0003007 156 0.015
regulation of hormone secretion GO:0046883 2 0.015
meiotic cell cycle process GO:1903046 3 0.015
cell death GO:0008219 121 0.015
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.015
viral process GO:0016032 1 0.015
developmental growth GO:0048589 166 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
cellular ketone metabolic process GO:0042180 11 0.015
dorsal ventral axis specification GO:0009950 14 0.015
intracellular mrna localization GO:0008298 1 0.015
positive regulation of nuclease activity GO:0032075 1 0.015
negative regulation of locomotion GO:0040013 18 0.014
neural retina development GO:0003407 49 0.014
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.014
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 1 0.014
positive regulation of phosphorus metabolic process GO:0010562 21 0.014
neuromuscular process GO:0050905 7 0.014
regulation of dendrite development GO:0050773 3 0.014
regulation of behavior GO:0050795 24 0.014
erythrocyte differentiation GO:0030218 54 0.014
mrna processing GO:0006397 14 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
photoreceptor cell differentiation GO:0046530 55 0.014
regulation of transport GO:0051049 45 0.014
inner ear receptor cell fate commitment GO:0060120 4 0.014
regulation of transferase activity GO:0051338 16 0.014
positive regulation of signal transduction GO:0009967 56 0.014
gtp catabolic process GO:0006184 2 0.014
positive regulation of chromosome segregation GO:0051984 1 0.014
cellular lipid metabolic process GO:0044255 36 0.014
cell proliferation in forebrain GO:0021846 3 0.014
positive regulation of signaling GO:0023056 56 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.014
ribosomal small subunit biogenesis GO:0042274 2 0.014
guanosine containing compound catabolic process GO:1901069 2 0.013
programmed cell death GO:0012501 119 0.013
purine ribonucleotide biosynthetic process GO:0009152 20 0.013
b cell differentiation GO:0030183 1 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
positive regulation of proteolysis GO:0045862 10 0.013
organic acid metabolic process GO:0006082 31 0.013
regulation of phosphorylation GO:0042325 26 0.013

hmgb1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.029
congenital nervous system abnormality DOID:2490 0 0.019