Danio rerio

81 known processes

spry4

sprouty (Drosophila) homolog 4

(Aliases: sprouty4,cb511,zSpry4,wu:fb92b06)

spry4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head development GO:0060322 303 0.999
regulation of transcription dna templated GO:0006355 213 0.998
organic cyclic compound metabolic process GO:1901360 301 0.996
neuron development GO:0048666 262 0.994
Fly
negative regulation of biological process GO:0048519 304 0.987
central nervous system development GO:0007417 387 0.987
regulation of biosynthetic process GO:0009889 250 0.987
aromatic compound biosynthetic process GO:0019438 217 0.986
regulation of macromolecule biosynthetic process GO:0010556 225 0.986
macromolecule biosynthetic process GO:0009059 227 0.985
regulation of primary metabolic process GO:0080090 311 0.984
Mouse
cellular response to chemical stimulus GO:0070887 157 0.982
cellular nitrogen compound metabolic process GO:0034641 290 0.972
cell migration GO:0016477 237 0.971
regulation of rna metabolic process GO:0051252 224 0.969
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.968
regulation of metabolic process GO:0019222 359 0.968
Mouse
response to organic substance GO:0010033 153 0.964
cellular macromolecule metabolic process GO:0044260 391 0.959
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.957
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.956
nucleic acid metabolic process GO:0090304 244 0.954
negative regulation of cellular process GO:0048523 283 0.951
diencephalon development GO:0021536 58 0.947
negative regulation of map kinase activity GO:0043407 2 0.942
Mouse
cellular component morphogenesis GO:0032989 336 0.942
cell morphogenesis involved in differentiation GO:0000904 195 0.940
signal transduction GO:0007165 455 0.940
axon development GO:0061564 166 0.940
blood vessel development GO:0001568 246 0.937
stem cell development GO:0048864 82 0.934
nucleobase containing compound metabolic process GO:0006139 274 0.931
nitrogen compound metabolic process GO:0006807 319 0.930
blood vessel morphogenesis GO:0048514 216 0.930
regulation of cellular biosynthetic process GO:0031326 245 0.927
regulation of rna biosynthetic process GO:2001141 213 0.927
heterocycle biosynthetic process GO:0018130 215 0.924
cellular biosynthetic process GO:0044249 286 0.924
nucleobase containing compound biosynthetic process GO:0034654 205 0.923
cellular aromatic compound metabolic process GO:0006725 295 0.920
heart morphogenesis GO:0003007 156 0.920
regulation of macromolecule metabolic process GO:0060255 317 0.917
Mouse
regulation of gene expression GO:0010468 265 0.916
sensory organ morphogenesis GO:0090596 200 0.909
Fly
positive regulation of metabolic process GO:0009893 108 0.907
localization of cell GO:0051674 244 0.903
transcription dna templated GO:0006351 181 0.899
positive regulation of cellular process GO:0048522 201 0.887
cellular macromolecule biosynthetic process GO:0034645 224 0.887
response to growth factor GO:0070848 39 0.886
locomotion GO:0040011 313 0.884
rna biosynthetic process GO:0032774 181 0.883
brain development GO:0007420 293 0.874
cell part morphogenesis GO:0032990 246 0.871
generation of neurons GO:0048699 385 0.870
Fly
regionalization GO:0003002 274 0.869
cell migration involved in gastrulation GO:0042074 79 0.869
ameboidal type cell migration GO:0001667 143 0.868
regulation of cellular metabolic process GO:0031323 320 0.864
Mouse
stem cell maintenance GO:0019827 4 0.858
cell projection organization GO:0030030 284 0.854
regulation of nitrogen compound metabolic process GO:0051171 251 0.850
regulation of nucleic acid templated transcription GO:1903506 213 0.845
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.843
mesoderm development GO:0007498 88 0.837
outflow tract morphogenesis GO:0003151 1 0.834
eye development GO:0001654 277 0.829
Fly
single organism localization GO:1902578 225 0.816
digestive tract morphogenesis GO:0048546 231 0.809
protein metabolic process GO:0019538 183 0.803
Mouse
regulation of developmental process GO:0050793 247 0.791
Fly
nucleic acid templated transcription GO:0097659 181 0.789
response to endogenous stimulus GO:0009719 83 0.787
mesoderm formation GO:0001707 43 0.785
neuron projection morphogenesis GO:0048812 161 0.780
regulation of cell cycle GO:0051726 52 0.776
positive regulation of macromolecule metabolic process GO:0010604 93 0.772
digestive tract development GO:0048565 265 0.769
multicellular organismal metabolic process GO:0044236 2 0.759
positive regulation of developmental process GO:0051094 50 0.758
regulation of multicellular organismal development GO:2000026 223 0.747
Fly
response to abiotic stimulus GO:0009628 122 0.744
cognition GO:0050890 1 0.743
neuron differentiation GO:0030182 353 0.733
Fly
cell morphogenesis GO:0000902 289 0.731
positive regulation of epithelial cell proliferation GO:0050679 1 0.726
cell projection morphogenesis GO:0048858 244 0.726
positive regulation of nucleic acid templated transcription GO:1903508 57 0.726
heart development GO:0007507 313 0.725
neuron projection guidance GO:0097485 86 0.724
cellular response to organic cyclic compound GO:0071407 38 0.718
endoderm development GO:0007492 49 0.712
single organism organelle organization GO:1902589 199 0.711
muscle structure development GO:0061061 196 0.710
response to chemical GO:0042221 320 0.706
organic cyclic compound biosynthetic process GO:1901362 223 0.701
dorsal ventral pattern formation GO:0009953 125 0.698
digestive system development GO:0055123 289 0.695
determination of heart left right asymmetry GO:0061371 117 0.694
regulation of cell differentiation GO:0045595 142 0.689
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.683
skeletal system development GO:0001501 181 0.673
camera type eye morphogenesis GO:0048593 108 0.670
rna metabolic process GO:0016070 219 0.668
neuron projection development GO:0031175 180 0.667
cartilage development GO:0051216 96 0.654
negative regulation of multicellular organismal process GO:0051241 69 0.653
regulation of cell size GO:0008361 29 0.653
embryonic heart tube morphogenesis GO:0003143 108 0.647
response to organic cyclic compound GO:0014070 51 0.646
phosphate containing compound metabolic process GO:0006796 108 0.644
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.641
Mouse
anterior posterior pattern specification GO:0009952 152 0.638
striated muscle cell differentiation GO:0051146 129 0.637
vasculogenesis GO:0001570 41 0.634
gene expression GO:0010467 252 0.631
regulation of cellular component size GO:0032535 30 0.626
chromosome organization GO:0051276 31 0.616
cellular response to endogenous stimulus GO:0071495 68 0.615
biosynthetic process GO:0009058 294 0.612
regulation of catalytic activity GO:0050790 55 0.611
Mouse
positive regulation of gene expression GO:0010628 71 0.611
taxis GO:0042330 109 0.609
heterocycle metabolic process GO:0046483 290 0.607
segmentation GO:0035282 97 0.606
response to external stimulus GO:0009605 264 0.605
cellular response to organic substance GO:0071310 105 0.600
homeostatic process GO:0042592 142 0.593
cell motility GO:0048870 244 0.593
neural tube development GO:0021915 62 0.582
ear development GO:0043583 127 0.579
metal ion homeostasis GO:0055065 26 0.569
hypothalamus development GO:0021854 14 0.563
gland development GO:0048732 143 0.561
limbic system development GO:0021761 16 0.560
negative regulation of mapk cascade GO:0043409 4 0.557
Mouse
phosphorylation GO:0016310 69 0.556
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.556
response to stress GO:0006950 263 0.552
regulation of signal transduction GO:0009966 225 0.548
apoptotic process GO:0006915 116 0.546
embryonic pattern specification GO:0009880 44 0.545
hemopoiesis GO:0030097 183 0.544
single organism cell adhesion GO:0098602 29 0.544
tissue remodeling GO:0048771 4 0.544
regulation of multicellular organismal process GO:0051239 277 0.534
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.533
regulation of establishment of protein localization GO:0070201 4 0.530
cellular protein metabolic process GO:0044267 129 0.529
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.525
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.523
hematopoietic or lymphoid organ development GO:0048534 191 0.517
somitogenesis GO:0001756 87 0.516
embryonic heart tube development GO:0035050 133 0.513
forebrain development GO:0030900 96 0.507
hypothalamus cell differentiation GO:0021979 4 0.506
cell surface receptor signaling pathway GO:0007166 325 0.505
stem cell differentiation GO:0048863 117 0.503
vasculature development GO:0001944 278 0.501
phosphorus metabolic process GO:0006793 109 0.499
Mouse
negative regulation of signal transduction GO:0009968 94 0.486
regulation of biological quality GO:0065008 263 0.484
actomyosin structure organization GO:0031032 53 0.482
growth GO:0040007 174 0.480
regulation of neural precursor cell proliferation GO:2000177 3 0.479
positive regulation of biological process GO:0048518 253 0.472
endoderm formation GO:0001706 29 0.471
heart looping GO:0001947 94 0.470
negative regulation of transcription dna templated GO:0045892 45 0.461
regulation of anatomical structure morphogenesis GO:0022603 130 0.460
Fly
calcium ion homeostasis GO:0055074 19 0.459
determination of left right symmetry GO:0007368 179 0.454
regulation of protein metabolic process GO:0051246 56 0.451
Mouse
cellular response to external stimulus GO:0071496 2 0.448
regulation of hormone secretion GO:0046883 2 0.447
cellular response to growth factor stimulus GO:0071363 39 0.445
regulation of cell communication GO:0010646 232 0.442
morphogenesis of an epithelium GO:0002009 333 0.441
Fly
ectodermal placode morphogenesis GO:0071697 32 0.439
organelle organization GO:0006996 227 0.437
mesenchyme development GO:0060485 127 0.423
regulation of phosphate metabolic process GO:0019220 43 0.423
Mouse
somite development GO:0061053 96 0.422
divalent inorganic cation homeostasis GO:0072507 22 0.420
negative regulation of gene expression GO:0010629 65 0.420
cellular response to nutrient levels GO:0031669 2 0.419
axon guidance GO:0007411 86 0.416
determination of bilateral symmetry GO:0009855 204 0.414
muscle cell development GO:0055001 115 0.414
axonogenesis GO:0007409 152 0.410
regulation of stem cell proliferation GO:0072091 2 0.405
negative regulation of metabolic process GO:0009892 86 0.403
Mouse
regulation of cardiac muscle tissue development GO:0055024 1 0.403
convergent extension GO:0060026 118 0.399
rhombomere 5 development GO:0021571 4 0.399
positive regulation of rna metabolic process GO:0051254 59 0.398
immune system process GO:0002376 241 0.396
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.394
programmed cell death GO:0012501 119 0.393
regulation of axon extension GO:0030516 24 0.392
negative regulation of mitosis GO:0045839 3 0.391
ossification GO:0001503 23 0.382
angiogenesis GO:0001525 158 0.370
mesoderm morphogenesis GO:0048332 51 0.366
rhombomere 6 development GO:0021572 4 0.365
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.364
regulation of neurogenesis GO:0050767 87 0.361
Fly
positive regulation of biosynthetic process GO:0009891 68 0.361
skeletal muscle organ development GO:0060538 78 0.360
cell death GO:0008219 121 0.357
single organism metabolic process GO:0044710 217 0.356
Mouse
cellular response to lipid GO:0071396 39 0.355
meiotic nuclear division GO:0007126 4 0.355
negative regulation of stem cell differentiation GO:2000737 2 0.352
regulation of locomotion GO:0040012 55 0.349
cellular component movement GO:0006928 335 0.346
cellular component assembly GO:0022607 170 0.346
cytoskeleton organization GO:0007010 96 0.344
regulation of apoptotic process GO:0042981 98 0.343
enzyme linked receptor protein signaling pathway GO:0007167 106 0.343
regeneration GO:0031099 91 0.343
positive regulation of response to stimulus GO:0048584 80 0.339
mesenchymal cell differentiation GO:0048762 87 0.338
negative regulation of cell communication GO:0010648 96 0.334
cellular response to stress GO:0033554 62 0.333
regulation of cellular response to growth factor stimulus GO:0090287 35 0.330
axis specification GO:0009798 43 0.326
endodermal cell differentiation GO:0035987 19 0.326
cellular response to extracellular stimulus GO:0031668 2 0.310
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.310
regulation of cell projection organization GO:0031344 44 0.310
positive regulation of map kinase activity GO:0043406 3 0.308
positive regulation of cellular metabolic process GO:0031325 94 0.304
camera type eye development GO:0043010 222 0.303
chemotaxis GO:0006935 104 0.303
convergent extension involved in gastrulation GO:0060027 71 0.302
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.302
endodermal cell fate specification GO:0001714 17 0.298
larval development GO:0002164 2 0.295
response to temperature stimulus GO:0009266 15 0.292
microtubule based process GO:0007017 60 0.291
positive regulation of cell differentiation GO:0045597 30 0.291
heart field specification GO:0003128 1 0.291
negative regulation of myeloid cell differentiation GO:0045638 1 0.289
organic substance biosynthetic process GO:1901576 289 0.289
regulation of cell development GO:0060284 100 0.288
Fly
appendage development GO:0048736 80 0.286
response to estrogen GO:0043627 27 0.285
hormone secretion GO:0046879 2 0.284
regulation of collagen metabolic process GO:0010712 2 0.284
regulation of sequestering of calcium ion GO:0051282 4 0.283
mesodermal cell differentiation GO:0048333 21 0.282
gastrulation GO:0007369 208 0.280
positive regulation of transport GO:0051050 2 0.279
regulation of cell death GO:0010941 103 0.277
negative regulation of response to stimulus GO:0048585 104 0.274
protein modification process GO:0036211 100 0.266
Mouse
negative regulation of cell migration GO:0030336 17 0.266
cell fate commitment GO:0045165 99 0.266
regulation of intracellular protein transport GO:0033157 3 0.266
dorsal ventral axis specification GO:0009950 14 0.264
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.262
cellular metal ion homeostasis GO:0006875 16 0.261
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.261
formation of primary germ layer GO:0001704 62 0.260
lipid storage GO:0019915 1 0.257
regulation of stem cell differentiation GO:2000736 4 0.254
oogenesis GO:0048477 14 0.254
hepaticobiliary system development GO:0061008 98 0.253
negative regulation of epithelial cell proliferation GO:0050680 1 0.250
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.248
negative regulation of nervous system development GO:0051961 22 0.247
negative regulation of cell differentiation GO:0045596 46 0.246
regulation of cell migration GO:0030334 40 0.246
inner ear morphogenesis GO:0042472 63 0.244
midbrain development GO:0030901 28 0.242
cell division GO:0051301 20 0.241
cellular cation homeostasis GO:0030003 17 0.241
positive regulation of nervous system development GO:0051962 25 0.239
heart formation GO:0060914 13 0.238
negative regulation of biosynthetic process GO:0009890 55 0.237
establishment of localization GO:0051234 244 0.236
regulation of cell division GO:0051302 12 0.236
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.235
maintenance of location GO:0051235 4 0.233
developmental growth involved in morphogenesis GO:0060560 86 0.232
developmental growth GO:0048589 166 0.232
protein phosphorylation GO:0006468 47 0.229
Mouse
neuroblast proliferation GO:0007405 2 0.228
negative regulation of signaling GO:0023057 96 0.227
multicellular organism growth GO:0035264 4 0.227
positive regulation of signal transduction GO:0009967 56 0.225
cellular homeostasis GO:0019725 26 0.225
death GO:0016265 121 0.224
embryo development ending in birth or egg hatching GO:0009792 271 0.223
cell proliferation GO:0008283 80 0.222
regulation of transferase activity GO:0051338 16 0.221
Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.221
regulation of catenin import into nucleus GO:0035412 2 0.220
negative regulation of cellular metabolic process GO:0031324 77 0.220
Mouse
reproductive process GO:0022414 40 0.218
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.216
response to drug GO:0042493 3 0.216
dendrite development GO:0016358 9 0.209
muscle tissue development GO:0060537 110 0.208
cardiac muscle cell development GO:0055013 20 0.207
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.206
aging GO:0007568 2 0.205
kupffer s vesicle development GO:0070121 50 0.205
photoreceptor cell differentiation GO:0046530 55 0.205
Fly
skeletal system morphogenesis GO:0048705 102 0.202
adrenal gland development GO:0030325 10 0.201
negative regulation of cell death GO:0060548 60 0.201
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.200
system process GO:0003008 185 0.199
cation transport GO:0006812 81 0.199
cellular amine metabolic process GO:0044106 2 0.199
mapk cascade GO:0000165 18 0.197
Mouse
immune system development GO:0002520 191 0.196
ion transport GO:0006811 114 0.194
regulation of neuron projection development GO:0010975 40 0.193
cellular component assembly involved in morphogenesis GO:0010927 107 0.192
regulation of metal ion transport GO:0010959 4 0.190
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.188
collagen metabolic process GO:0032963 2 0.187
cellular carbohydrate metabolic process GO:0044262 4 0.184
positive regulation of cell cycle GO:0045787 3 0.184
regulation of homeostatic process GO:0032844 9 0.181
endodermal cell fate commitment GO:0001711 18 0.181
tissue migration GO:0090130 37 0.180
regulation of erk1 and erk2 cascade GO:0070372 4 0.179
female sex differentiation GO:0046660 4 0.178
germ cell migration GO:0008354 8 0.178
wound healing GO:0042060 90 0.177
specification of organ identity GO:0010092 2 0.177
forebrain anterior posterior pattern specification GO:0021797 3 0.176
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.176
behavior GO:0007610 74 0.175
regulation of cell motility GO:2000145 46 0.172
sequestering of metal ion GO:0051238 3 0.171
somatic muscle development GO:0007525 4 0.170
cation homeostasis GO:0055080 33 0.169
erk1 and erk2 cascade GO:0070371 4 0.168
oocyte development GO:0048599 14 0.168
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.168
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.167
regulation of protein import into nucleus GO:0042306 2 0.166
positive regulation of signaling GO:0023056 56 0.163
stem cell proliferation GO:0072089 4 0.163
multicellular organismal homeostasis GO:0048871 29 0.163
cellular response to lipopolysaccharide GO:0071222 3 0.162
chemosensory behavior GO:0007635 1 0.159
negative regulation of hormone secretion GO:0046888 2 0.157
regulation of programmed cell death GO:0043067 101 0.155
eye morphogenesis GO:0048592 144 0.155
Fly
striated muscle cell development GO:0055002 108 0.154
detection of external stimulus GO:0009581 24 0.153
retina development in camera type eye GO:0060041 146 0.153
optic placode formation involved in camera type eye formation GO:0046619 3 0.153
chordate embryonic development GO:0043009 271 0.151
positive regulation of secretion by cell GO:1903532 1 0.151
regulation of embryonic development GO:0045995 47 0.150
myeloid leukocyte differentiation GO:0002573 15 0.150
regulation of protein transport GO:0051223 3 0.150
regulation of neuron differentiation GO:0045664 56 0.149
Fly
ectodermal placode formation GO:0060788 26 0.148
negative regulation of cellular component organization GO:0051129 16 0.147
regulation of chondrocyte differentiation GO:0032330 1 0.146
gastrulation with mouth forming second GO:0001702 44 0.146
dephosphorylation GO:0016311 11 0.145
positive regulation of cell development GO:0010720 25 0.145
otic vesicle formation GO:0030916 27 0.144
monocyte differentiation GO:0030224 2 0.144
negative regulation of cell adhesion GO:0007162 6 0.143
regulation of mitotic cell cycle GO:0007346 25 0.143
establishment of protein localization to organelle GO:0072594 4 0.142
regulation of protein localization to nucleus GO:1900180 2 0.142
sensory organ development GO:0007423 393 0.141
Fly
regulation of response to stimulus GO:0048583 269 0.141
regulation of nervous system development GO:0051960 90 0.140
Fly
germ line stem cell maintenance GO:0030718 2 0.140
negative regulation of bmp signaling pathway GO:0030514 13 0.138
negative regulation of intracellular signal transduction GO:1902532 22 0.137
Mouse
chemical homeostasis GO:0048878 49 0.135
development of primary female sexual characteristics GO:0046545 4 0.134
specification of symmetry GO:0009799 204 0.133
negative regulation of sequestering of calcium ion GO:0051283 4 0.133
cell migration involved in heart development GO:0060973 22 0.133
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.132
tube morphogenesis GO:0035239 349 0.132
Fly
endothelial cell migration GO:0043542 19 0.131
protein targeting to nucleus GO:0044744 3 0.131
regulation of anatomical structure size GO:0090066 33 0.131
regulation of cell fate commitment GO:0010453 22 0.130
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.127
detection of stimulus GO:0051606 29 0.127
regulation of endodermal cell fate specification GO:0042663 15 0.126
cranial nerve development GO:0021545 42 0.125
regulation of myeloid cell differentiation GO:0045637 8 0.124
muscle cell differentiation GO:0042692 139 0.124
cellular response to steroid hormone stimulus GO:0071383 31 0.124
signal transduction by phosphorylation GO:0023014 18 0.123
Mouse
epithelial tube morphogenesis GO:0060562 148 0.123
Fly
regulation of protein targeting GO:1903533 2 0.122
negative regulation of rna metabolic process GO:0051253 48 0.122
cellular response to prostaglandin stimulus GO:0071379 3 0.121
spinal cord development GO:0021510 46 0.121
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.119
regulation of translation GO:0006417 3 0.119
regulation of organelle organization GO:0033043 29 0.118
negative regulation of neurogenesis GO:0050768 20 0.118
negative regulation of nuclear division GO:0051784 3 0.116
circadian rhythm GO:0007623 19 0.116
ceramide biosynthetic process GO:0046513 1 0.116
tissue regeneration GO:0042246 74 0.116
post anal tail morphogenesis GO:0036342 19 0.115
cellular protein modification process GO:0006464 100 0.115
Mouse
activin receptor signaling pathway GO:0032924 8 0.114
biomineral tissue development GO:0031214 13 0.112
hindbrain development GO:0030902 91 0.112
cellular chemical homeostasis GO:0055082 17 0.112
regulation of hydrolase activity GO:0051336 28 0.112
regulation of phosphorylation GO:0042325 26 0.111
Mouse
cardiac muscle cell differentiation GO:0055007 30 0.111
organic substance transport GO:0071702 58 0.111
cellular extravasation GO:0045123 1 0.109
negative regulation of wnt signaling pathway GO:0030178 30 0.109
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.109
negative regulation of developmental process GO:0051093 65 0.109
regulation of multicellular organismal metabolic process GO:0044246 2 0.108
striated muscle tissue development GO:0014706 110 0.107
regulation of chemotaxis GO:0050920 18 0.107
hematopoietic progenitor cell differentiation GO:0002244 23 0.106
axon extension involved in axon guidance GO:0048846 10 0.105
cellular component biogenesis GO:0044085 178 0.104
negative regulation of cardiac muscle cell differentiation GO:2000726 1 0.103
regulation of cell cycle process GO:0010564 20 0.103
somatic stem cell maintenance GO:0035019 1 0.103
regulation of cellular amino acid metabolic process GO:0006521 0 0.102
positive regulation of cell communication GO:0010647 56 0.102
cardiac cell development GO:0055006 21 0.102
hepatocyte proliferation GO:0072574 2 0.101
carbohydrate homeostasis GO:0033500 1 0.100
neural crest cell differentiation GO:0014033 72 0.099
detection of temperature stimulus involved in sensory perception GO:0050961 0 0.099
heart jogging GO:0003146 40 0.098
intracellular signal transduction GO:0035556 85 0.097
Mouse
neuronal stem cell maintenance GO:0097150 2 0.097
multicellular organismal macromolecule metabolic process GO:0044259 2 0.097
determination of dorsal ventral asymmetry GO:0048262 34 0.097
cellular response to cytokine stimulus GO:0071345 7 0.096
bone remodeling GO:0046849 2 0.095
epithelial to mesenchymal transition GO:0001837 21 0.095
regulation of cell growth GO:0001558 29 0.095
neural crest formation GO:0014029 14 0.095
response to nitrogen compound GO:1901698 19 0.094
biological adhesion GO:0022610 40 0.094
multicellular organismal reproductive process GO:0048609 35 0.094
regulation of localization GO:0032879 104 0.092
negative regulation of nucleic acid templated transcription GO:1903507 45 0.092
cell fate specification GO:0001708 68 0.092
amine metabolic process GO:0009308 2 0.091
phagocytosis engulfment GO:0006911 1 0.091
regulation of behavior GO:0050795 24 0.091
regulation of cell fate specification GO:0042659 20 0.091
cellular ion homeostasis GO:0006873 17 0.091
regulation of bmp signaling pathway GO:0030510 39 0.090
angioblast cell differentiation GO:0035779 2 0.090
connective tissue development GO:0061448 99 0.090
response to hormone GO:0009725 48 0.090
fin regeneration GO:0031101 51 0.089
cytosolic calcium ion transport GO:0060401 3 0.089
positive regulation of cytokine production GO:0001819 2 0.088
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.088
syncytium formation GO:0006949 12 0.088
nerve development GO:0021675 45 0.087
inner ear development GO:0048839 126 0.087
myeloid cell differentiation GO:0030099 86 0.087
negative regulation of protein kinase activity GO:0006469 4 0.086
Mouse
protein localization to nucleus GO:0034504 3 0.086
multi organism process GO:0051704 134 0.086
central nervous system neuron differentiation GO:0021953 74 0.085
response to nutrient GO:0007584 3 0.085
multi organism reproductive process GO:0044703 36 0.084
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.084
macromolecular complex subunit organization GO:0043933 74 0.082
response to bacterium GO:0009617 58 0.082
nuclear transport GO:0051169 4 0.082
epithelial cell proliferation GO:0050673 17 0.082
body morphogenesis GO:0010171 16 0.082
negative regulation of endothelial cell migration GO:0010596 1 0.081
cellular amino acid metabolic process GO:0006520 7 0.081
negative regulation of protein phosphorylation GO:0001933 4 0.081
Mouse

spry4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.384
musculoskeletal system disease DOID:17 0 0.132
connective tissue disease DOID:65 0 0.132
bone development disease DOID:0080006 0 0.112
bone disease DOID:0080001 0 0.112
dysostosis DOID:1934 0 0.112