Danio rerio

0 known processes

LOC100005454

Gig2-like protein DreK

LOC100005454 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
urea transmembrane transport GO:0071918 9 0.216
glycerol transport GO:0015793 7 0.181
fluid transport GO:0042044 17 0.168
ion transmembrane transport GO:0034220 91 0.156
ammonium transmembrane transport GO:0072488 2 0.146
inorganic ion transmembrane transport GO:0098660 57 0.127
one carbon compound transport GO:0019755 14 0.120
water transport GO:0006833 15 0.116
signal transduction GO:0007165 455 0.106
immune system process GO:0002376 241 0.104
monovalent inorganic cation transport GO:0015672 42 0.098
transport GO:0006810 220 0.093
cell surface receptor signaling pathway GO:0007166 325 0.093
single organism transport GO:0044765 206 0.079
larval development GO:0002164 2 0.076
carbon dioxide transmembrane transport GO:0035378 1 0.068
establishment of localization GO:0051234 244 0.065
positive regulation of cell cycle GO:0045787 3 0.065
g protein coupled receptor signaling pathway GO:0007186 74 0.060
response to glucocorticoid GO:0051384 1 0.058
sensory organ development GO:0007423 393 0.056
ion transport GO:0006811 114 0.055
response to stress GO:0006950 263 0.055
defense response to other organism GO:0098542 33 0.050
eye development GO:0001654 277 0.050
transcription dna templated GO:0006351 181 0.050
aging GO:0007568 2 0.049
rna metabolic process GO:0016070 219 0.047
multicellular organism growth GO:0035264 4 0.046
nucleocytoplasmic transport GO:0006913 4 0.045
positive regulation of transport GO:0051050 2 0.045
response to external biotic stimulus GO:0043207 97 0.045
single organism localization GO:1902578 225 0.044
inorganic anion transport GO:0015698 25 0.042
carbon dioxide transport GO:0015670 3 0.040
nuclear transport GO:0051169 4 0.040
response to organic substance GO:0010033 153 0.039
homeostatic process GO:0042592 142 0.039
polyol transport GO:0015791 7 0.039
cellular macromolecule biosynthetic process GO:0034645 224 0.037
central nervous system development GO:0007417 387 0.036
regulation of multicellular organism growth GO:0040014 4 0.036
regulation of metal ion transport GO:0010959 4 0.036
transmembrane transport GO:0055085 120 0.035
regulation of gene expression GO:0010468 265 0.034
regulation of cytokine production GO:0001817 3 0.034
regulation of multicellular organismal process GO:0051239 277 0.034
establishment of protein localization to organelle GO:0072594 4 0.033
urea transport GO:0015840 11 0.032
response to chemical GO:0042221 320 0.032
phagocytosis GO:0006909 3 0.032
cellular amine metabolic process GO:0044106 2 0.032
camera type eye development GO:0043010 222 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
lipid homeostasis GO:0055088 3 0.031
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.030
response to carbohydrate GO:0009743 3 0.030
regulation of response to stimulus GO:0048583 269 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.029
maintenance of location GO:0051235 4 0.029
regulation of rna biosynthetic process GO:2001141 213 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
cation transmembrane transport GO:0098655 65 0.028
response to external stimulus GO:0009605 264 0.028
multi organism process GO:0051704 134 0.028
head development GO:0060322 303 0.028
nucleic acid templated transcription GO:0097659 181 0.028
lipid storage GO:0019915 1 0.027
tube morphogenesis GO:0035239 349 0.027
regulation of protein catabolic process GO:0042176 1 0.027
protein targeting to nucleus GO:0044744 3 0.027
cellular response to chemical stimulus GO:0070887 157 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.026
brain development GO:0007420 293 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
rna biosynthetic process GO:0032774 181 0.026
nuclear import GO:0051170 3 0.026
meiotic nuclear division GO:0007126 4 0.025
chordate embryonic development GO:0043009 271 0.025
cellular response to external stimulus GO:0071496 2 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
organelle organization GO:0006996 227 0.025
regulation of primary metabolic process GO:0080090 311 0.025
heterocycle metabolic process GO:0046483 290 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
immune response GO:0006955 28 0.024
stem cell proliferation GO:0072089 4 0.024
regulation of binding GO:0051098 3 0.024
specification of symmetry GO:0009799 204 0.024
response to corticosteroid GO:0031960 1 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
digestive system development GO:0055123 289 0.023
protein acetylation GO:0006473 2 0.023
response to glucose GO:0009749 3 0.023
negative regulation of cytokine production GO:0001818 1 0.023
lipid catabolic process GO:0016042 4 0.023
regulation of biosynthetic process GO:0009889 250 0.023
gtp metabolic process GO:0046039 4 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
glucose homeostasis GO:0042593 1 0.022
cellular response to organic substance GO:0071310 105 0.022
lymphocyte proliferation GO:0046651 1 0.022
biosynthetic process GO:0009058 294 0.022
cellular response to starvation GO:0009267 1 0.022
hormone secretion GO:0046879 2 0.022
regulation of transcription dna templated GO:0006355 213 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
protein import into nucleus GO:0006606 3 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
protein localization to nucleus GO:0034504 3 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
response to nutrient GO:0007584 3 0.022
positive regulation of catabolic process GO:0009896 4 0.022
negative regulation of dna metabolic process GO:0051053 4 0.022
response to hexose GO:0009746 3 0.022
cellular ketone metabolic process GO:0042180 11 0.021
locomotion GO:0040011 313 0.021
mononuclear cell proliferation GO:0032943 1 0.021
meiotic cell cycle process GO:1903046 3 0.021
positive regulation of immune effector process GO:0002699 3 0.021
regulation of signal transduction GO:0009966 225 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
autophagy GO:0006914 4 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
positive regulation of cytokine production GO:0001819 2 0.021
gene expression GO:0010467 252 0.021
cellular macromolecule metabolic process GO:0044260 391 0.020
regulation of cell communication GO:0010646 232 0.020
renal absorption GO:0070293 1 0.020
cation transport GO:0006812 81 0.020
regulation of cell activation GO:0050865 1 0.020
stem cell maintenance GO:0019827 4 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
ovulation cycle process GO:0022602 2 0.020
single organism nuclear import GO:1902593 3 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
nucleic acid metabolic process GO:0090304 244 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
regulation of reproductive process GO:2000241 4 0.020
organic substance transport GO:0071702 58 0.020
defense response to bacterium GO:0042742 22 0.019
regulation of signaling GO:0023051 235 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
regulation of ph GO:0006885 3 0.019
negative regulation of catabolic process GO:0009895 3 0.019
regulation of protein complex assembly GO:0043254 3 0.019
regulation of inflammatory response GO:0050727 2 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
water homeostasis GO:0030104 4 0.019
carbohydrate transport GO:0008643 13 0.019
regulation of developmental process GO:0050793 247 0.019
digestive tract development GO:0048565 265 0.019
inorganic cation transmembrane transport GO:0098662 50 0.019
regulation of metabolic process GO:0019222 359 0.019
organic hydroxy compound transport GO:0015850 14 0.019
gas transport GO:0015669 3 0.019
negative regulation of nuclear division GO:0051784 3 0.019
response to monosaccharide GO:0034284 3 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
amine metabolic process GO:0009308 2 0.018
negative regulation of biological process GO:0048519 304 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
positive regulation of secretion GO:0051047 1 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
protein acylation GO:0043543 3 0.018
response to other organism GO:0051707 97 0.018
endocrine process GO:0050886 2 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.018
defense response GO:0006952 47 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
response to ketone GO:1901654 1 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
positive regulation of cell activation GO:0050867 1 0.018
regulation of autophagy GO:0010506 3 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
long chain fatty acid metabolic process GO:0001676 1 0.018
vasculature development GO:0001944 278 0.018
positive regulation of biological process GO:0048518 253 0.017
tissue remodeling GO:0048771 4 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
regulation of protein transport GO:0051223 3 0.017
positive regulation of leukocyte mediated immunity GO:0002705 1 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
regulation of transporter activity GO:0032409 2 0.017
hemopoiesis GO:0030097 183 0.017
regulation of cell killing GO:0031341 2 0.017
cellular component biogenesis GO:0044085 178 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
developmental growth GO:0048589 166 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
b cell activation GO:0042113 2 0.017
sensory organ morphogenesis GO:0090596 200 0.017
leukocyte proliferation GO:0070661 1 0.017
mitochondrion organization GO:0007005 4 0.017
protein metabolic process GO:0019538 183 0.017
cellular component assembly GO:0022607 170 0.016
protein import GO:0017038 3 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
regulation of production of molecular mediator of immune response GO:0002700 1 0.016
response to bacterium GO:0009617 58 0.016
regionalization GO:0003002 274 0.016
carbohydrate homeostasis GO:0033500 1 0.016
digestive tract morphogenesis GO:0048546 231 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
neuromast development GO:0048884 46 0.016
somitogenesis GO:0001756 87 0.016
female gonad development GO:0008585 4 0.016
anion transport GO:0006820 38 0.016
regulation of dna replication GO:0006275 3 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
adult behavior GO:0030534 2 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
multicellular organismal water homeostasis GO:0050891 1 0.016
regulation of hormone secretion GO:0046883 2 0.016
regulation of biological quality GO:0065008 263 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
negative regulation of cellular process GO:0048523 283 0.016
retina development in camera type eye GO:0060041 146 0.016
protein secretion GO:0009306 1 0.016
positive regulation of cell division GO:0051781 2 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
negative regulation of gene expression GO:0010629 65 0.016
spermatid differentiation GO:0048515 2 0.016
morphogenesis of an epithelial sheet GO:0002011 49 0.016
oxoacid metabolic process GO:0043436 31 0.015
small molecule catabolic process GO:0044282 3 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of tube size GO:0035150 2 0.015
response to vitamin GO:0033273 3 0.015
protein heterooligomerization GO:0051291 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
regulation of blood vessel size GO:0050880 2 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.015
establishment of endothelial barrier GO:0061028 3 0.015
regulation of systemic arterial blood pressure GO:0003073 1 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
response to topologically incorrect protein GO:0035966 2 0.015
positive regulation of gene expression GO:0010628 71 0.015
regulation of sodium ion transport GO:0002028 2 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
somatic cell dna recombination GO:0016444 1 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
regulation of rna metabolic process GO:0051252 224 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
fatty acid transport GO:0015908 1 0.015
gtp catabolic process GO:0006184 2 0.015
regulation of response to extracellular stimulus GO:0032104 1 0.014
somite development GO:0061053 96 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
stem cell division GO:0017145 1 0.014
positive regulation of rna metabolic process GO:0051254 59 0.014
single organism organelle organization GO:1902589 199 0.014
response to wounding GO:0009611 116 0.014
epiboly GO:0090504 41 0.014
cellular response to light stimulus GO:0071482 4 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of gtpase activity GO:0043087 2 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
photoreceptor cell fate commitment GO:0046552 1 0.014
b cell mediated immunity GO:0019724 3 0.014
regulation of blood pressure GO:0008217 1 0.014
positive regulation of blood circulation GO:1903524 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of organ growth GO:0046620 3 0.014
positive regulation of cell killing GO:0031343 2 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
somatic muscle development GO:0007525 4 0.014
cell migration GO:0016477 237 0.014
cellular lipid catabolic process GO:0044242 3 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
atp catabolic process GO:0006200 4 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
system process GO:0003008 185 0.013
phagocytosis engulfment GO:0006911 1 0.013
female sex differentiation GO:0046660 4 0.013
ovulation cycle GO:0042698 2 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
macroautophagy GO:0016236 1 0.013
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
gastrulation GO:0007369 208 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
organic acid metabolic process GO:0006082 31 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
membrane invagination GO:0010324 1 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
regulation of leukocyte mediated immunity GO:0002703 1 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
organic substance biosynthetic process GO:1901576 289 0.013
cellular protein metabolic process GO:0044267 129 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
insulin like growth factor receptor signaling pathway GO:0048009 4 0.013
positive regulation of cellular process GO:0048522 201 0.013
positive regulation of reproductive process GO:2000243 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
single organism metabolic process GO:0044710 217 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
cellular protein modification process GO:0006464 100 0.013
sex determination GO:0007530 1 0.013
embryonic organ development GO:0048568 381 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
organic acid catabolic process GO:0016054 3 0.013
cellular protein catabolic process GO:0044257 4 0.013
spermatid development GO:0007286 2 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
very long chain fatty acid metabolic process GO:0000038 4 0.012
peptide transport GO:0015833 1 0.012
intracellular signal transduction GO:0035556 85 0.012
long chain fatty acid transport GO:0015909 1 0.012
cell morphogenesis GO:0000902 289 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
camera type eye morphogenesis GO:0048593 108 0.012
regulation of protein targeting GO:1903533 2 0.012
cellular response to radiation GO:0071478 4 0.012
blood vessel development GO:0001568 246 0.012
ear development GO:0043583 127 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
urogenital system development GO:0001655 97 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.012
regulation of cellular ph GO:0030641 1 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
positive regulation of histone modification GO:0031058 1 0.012
regulation of p38mapk cascade GO:1900744 1 0.012
single fertilization GO:0007338 3 0.012
leukocyte mediated cytotoxicity GO:0001909 1 0.012
determination of left right symmetry GO:0007368 179 0.011
interspecies interaction between organisms GO:0044419 4 0.011
small molecule metabolic process GO:0044281 77 0.011
anterior posterior pattern specification GO:0009952 152 0.011
heart development GO:0007507 313 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
regulation of wound healing GO:0061041 2 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.011
immune system development GO:0002520 191 0.011
negative regulation of protein transport GO:0051224 3 0.011
regulation of growth rate GO:0040009 1 0.011
response to uv GO:0009411 3 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
amide transport GO:0042886 12 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
regulation of intracellular ph GO:0051453 1 0.011
response to biotic stimulus GO:0009607 97 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
response to alkaloid GO:0043279 2 0.011
hormone transport GO:0009914 2 0.011
modulation by virus of host morphology or physiology GO:0019048 1 0.011
growth GO:0040007 174 0.011
negative regulation of kinase activity GO:0033673 4 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.011
regulation of protein binding GO:0043393 3 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
rna localization GO:0006403 4 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
p38mapk cascade GO:0038066 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
positive regulation of inflammatory response GO:0050729 1 0.011
immunoglobulin production GO:0002377 1 0.011
regulation of natural killer cell mediated immunity GO:0002715 1 0.011
pyruvate metabolic process GO:0006090 1 0.011
macromolecule modification GO:0043412 111 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
negative regulation of signal transduction GO:0009968 94 0.010
cellular response to organic cyclic compound GO:0071407 38 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
endosomal transport GO:0016197 2 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
inner ear development GO:0048839 126 0.010
response to endogenous stimulus GO:0009719 83 0.010
gastrulation with mouth forming second GO:0001702 44 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
germ line stem cell maintenance GO:0030718 2 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
chloride transmembrane transport GO:1902476 4 0.010
eye morphogenesis GO:0048592 144 0.010
determination of bilateral symmetry GO:0009855 204 0.010
cytokinesis GO:0000910 3 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
compound eye development GO:0048749 2 0.010
dicarboxylic acid transport GO:0006835 1 0.010

LOC100005454 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
disease of metabolism DOID:0014667 0 0.015
nervous system disease DOID:863 0 0.013
inherited metabolic disorder DOID:655 0 0.013
musculoskeletal system disease DOID:17 0 0.011