Danio rerio

0 known processes

LOC100331484

hypothetical protein LOC100331484

LOC100331484 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleic acid metabolic process GO:0090304 244 0.389
osteoclast differentiation GO:0030316 1 0.256
positive regulation of neuron apoptotic process GO:0043525 1 0.230
regulation of myeloid leukocyte differentiation GO:0002761 5 0.172
nuclear transport GO:0051169 4 0.146
negative regulation of biological process GO:0048519 304 0.134
locomotor rhythm GO:0045475 3 0.125
negative regulation of metabolic process GO:0009892 86 0.121
regulation of nitrogen compound metabolic process GO:0051171 251 0.121
developmental growth involved in morphogenesis GO:0060560 86 0.116
activation of mapkkk activity GO:0000185 1 0.100
cellular aromatic compound metabolic process GO:0006725 295 0.100
response to virus GO:0009615 21 0.097
cognition GO:0050890 1 0.093
larval development GO:0002164 2 0.088
antimicrobial humoral response GO:0019730 2 0.083
cellular macromolecule metabolic process GO:0044260 391 0.081
regulation of metabolic process GO:0019222 359 0.074
glomerular epithelial cell fate commitment GO:0072314 4 0.073
response to glucocorticoid GO:0051384 1 0.072
skeletal muscle organ development GO:0060538 78 0.068
response to chemical GO:0042221 320 0.067
cellular macromolecule biosynthetic process GO:0034645 224 0.065
positive regulation of leukocyte differentiation GO:1902107 1 0.063
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.062
aging GO:0007568 2 0.061
regeneration GO:0031099 91 0.061
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.060
nucleobase containing compound biosynthetic process GO:0034654 205 0.059
single organism nuclear import GO:1902593 3 0.059
g2 m transition of mitotic cell cycle GO:0000086 4 0.057
regulation of response to interferon gamma GO:0060330 1 0.056
regulation of endothelial cell proliferation GO:0001936 1 0.054
striated muscle tissue development GO:0014706 110 0.054
regulation of endodermal cell differentiation GO:1903224 15 0.053
regulation of reproductive process GO:2000241 4 0.052
response to stress GO:0006950 263 0.051
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.049
nucleocytoplasmic transport GO:0006913 4 0.049
compound eye development GO:0048749 2 0.048
negative regulation of protein phosphorylation GO:0001933 4 0.048
cell cycle g2 m phase transition GO:0044839 4 0.048
sleep GO:0030431 1 0.046
response to external biotic stimulus GO:0043207 97 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.044
biosynthetic process GO:0009058 294 0.043
p38mapk cascade GO:0038066 1 0.042
positive regulation of epithelial cell proliferation GO:0050679 1 0.042
cellular biosynthetic process GO:0044249 286 0.041
intracellular signal transduction GO:0035556 85 0.041
regulation of macromolecule biosynthetic process GO:0010556 225 0.041
transcription dna templated GO:0006351 181 0.041
regulation of multicellular organismal process GO:0051239 277 0.041
transcription from rna polymerase ii promoter GO:0006366 80 0.040
dorsal ventral pattern formation GO:0009953 125 0.039
response to light stimulus GO:0009416 46 0.039
protein import into nucleus GO:0006606 3 0.039
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.039
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.038
skeletal muscle tissue development GO:0007519 67 0.037
positive regulation of neuron death GO:1901216 1 0.037
muscle structure development GO:0061061 196 0.035
cell fate commitment GO:0045165 99 0.035
positive regulation of myeloid leukocyte differentiation GO:0002763 1 0.034
positive regulation of cell death GO:0010942 29 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.034
response to drug GO:0042493 3 0.034
establishment of protein localization to organelle GO:0072594 4 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.033
signal transduction GO:0007165 455 0.033
protein import GO:0017038 3 0.033
response to corticosteroid GO:0031960 1 0.032
response to ketone GO:1901654 1 0.032
regulation of rna biosynthetic process GO:2001141 213 0.032
positive regulation of myeloid cell differentiation GO:0045639 2 0.031
myeloid leukocyte differentiation GO:0002573 15 0.031
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.031
nuclear import GO:0051170 3 0.031
response to immobilization stress GO:0035902 1 0.030
protein localization to nucleus GO:0034504 3 0.030
macromolecule biosynthetic process GO:0009059 227 0.030
organic substance biosynthetic process GO:1901576 289 0.030
protein targeting to nucleus GO:0044744 3 0.029
dopaminergic neuron differentiation GO:0071542 14 0.029
regulation of interferon gamma mediated signaling pathway GO:0060334 1 0.028
negative regulation of map kinase activity GO:0043407 2 0.028
sensory organ development GO:0007423 393 0.028
regulation of rna metabolic process GO:0051252 224 0.028
multi organism process GO:0051704 134 0.028
nucleic acid templated transcription GO:0097659 181 0.028
tube morphogenesis GO:0035239 349 0.027
response to other organism GO:0051707 97 0.027
regulation of gastrulation GO:0010470 24 0.027
positive regulation of jnk cascade GO:0046330 3 0.027
digestive system development GO:0055123 289 0.027
enzyme linked receptor protein signaling pathway GO:0007167 106 0.026
regulation of synaptic plasticity GO:0048167 1 0.026
blood vessel development GO:0001568 246 0.026
negative regulation of macromolecule metabolic process GO:0010605 76 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
cellular response to chemical stimulus GO:0070887 157 0.025
outflow tract morphogenesis GO:0003151 1 0.024
regulation of developmental process GO:0050793 247 0.024
cellular response to reactive oxygen species GO:0034614 2 0.024
humoral immune response GO:0006959 5 0.024
cellular response to external stimulus GO:0071496 2 0.023
phagocytosis GO:0006909 3 0.023
collateral sprouting GO:0048668 9 0.023
regulation of dna replication GO:0006275 3 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
programmed cell death GO:0012501 119 0.023
response to external stimulus GO:0009605 264 0.023
meiotic chromosome segregation GO:0045132 3 0.023
muscle tissue development GO:0060537 110 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
negative regulation of cellular process GO:0048523 283 0.022
rna metabolic process GO:0016070 219 0.022
organic cyclic compound metabolic process GO:1901360 301 0.021
regulation of gene expression GO:0010468 265 0.021
regionalization GO:0003002 274 0.021
positive regulation of multi organism process GO:0043902 3 0.021
response to biotic stimulus GO:0009607 97 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
negative regulation of signaling GO:0023057 96 0.021
regulation of cytoplasmic transport GO:1903649 4 0.020
viral process GO:0016032 1 0.020
heterocycle metabolic process GO:0046483 290 0.020
regulation of catalytic activity GO:0050790 55 0.020
response to cold GO:0009409 4 0.020
protein metabolic process GO:0019538 183 0.020
positive regulation of programmed cell death GO:0043068 29 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
mesenchyme development GO:0060485 127 0.020
positive regulation of stress activated mapk cascade GO:0032874 3 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
response to growth factor GO:0070848 39 0.020
interferon gamma mediated signaling pathway GO:0060333 1 0.020
regulation of transcription dna templated GO:0006355 213 0.019
rna biosynthetic process GO:0032774 181 0.019
axon regeneration GO:0031103 14 0.019
apoptotic process involved in morphogenesis GO:0060561 2 0.019
mitotic cell cycle GO:0000278 64 0.019
negative regulation of kinase activity GO:0033673 4 0.019
cellular response to decreased oxygen levels GO:0036294 1 0.019
lipid storage GO:0019915 1 0.019
regulation of dna templated transcription in response to stress GO:0043620 0 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
regulation of protein localization to nucleus GO:1900180 2 0.018
regulation of biosynthetic process GO:0009889 250 0.018
negative regulation of apoptotic process GO:0043066 55 0.018
macromolecule modification GO:0043412 111 0.018
negative regulation of transcription dna templated GO:0045892 45 0.018
regulation of protein targeting GO:1903533 2 0.018
mitochondrion organization GO:0007005 4 0.017
positive regulation of epithelial cell migration GO:0010634 2 0.017
interspecies interaction between organisms GO:0044419 4 0.017
cellular protein metabolic process GO:0044267 129 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
vasculature development GO:0001944 278 0.017
eye development GO:0001654 277 0.017
single organism metabolic process GO:0044710 217 0.017
cell cycle GO:0007049 93 0.017
neuron differentiation GO:0030182 353 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.017
monocyte differentiation GO:0030224 2 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
myeloid cell differentiation GO:0030099 86 0.016
response to wounding GO:0009611 116 0.016
peptide transport GO:0015833 1 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
negative regulation of molecular function GO:0044092 23 0.016
regulation of primary metabolic process GO:0080090 311 0.016
response to transition metal nanoparticle GO:1990267 28 0.016
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.016
muscle organ development GO:0007517 101 0.016
growth GO:0040007 174 0.016
cellular response to growth factor stimulus GO:0071363 39 0.016
skeletal muscle cell differentiation GO:0035914 5 0.016
meiotic cell cycle process GO:1903046 3 0.015
regulation of blood pressure GO:0008217 1 0.015
maintenance of location GO:0051235 4 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.015
rhombomere 5 development GO:0021571 4 0.015
cell morphogenesis GO:0000902 289 0.015
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 1 0.015
cellular component movement GO:0006928 335 0.014
positive regulation of transport GO:0051050 2 0.014
chordate embryonic development GO:0043009 271 0.014
camera type eye development GO:0043010 222 0.014
circadian rhythm GO:0007623 19 0.014
angiogenesis GO:0001525 158 0.014
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
spindle assembly GO:0051225 2 0.014
nephron morphogenesis GO:0072028 2 0.014
regulation of inflammatory response GO:0050727 2 0.014
gtp catabolic process GO:0006184 2 0.014
reciprocal dna recombination GO:0035825 1 0.014
renal tubule morphogenesis GO:0061333 1 0.014
developmental growth GO:0048589 166 0.014
cell fate specification GO:0001708 68 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
negative regulation of protein localization to nucleus GO:1900181 2 0.014
response to inorganic substance GO:0010035 38 0.014
cellular component disassembly GO:0022411 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
autophagy GO:0006914 4 0.013
action potential GO:0001508 19 0.013
response to bacterium GO:0009617 58 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
negative regulation of neuron projection regeneration GO:0070571 4 0.013
cellular response to organic substance GO:0071310 105 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
positive regulation of catabolic process GO:0009896 4 0.013
negative regulation of protein transport GO:0051224 3 0.012
regulation of protein transport GO:0051223 3 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
multicellular organism growth GO:0035264 4 0.012
cell aging GO:0007569 2 0.012
tissue regeneration GO:0042246 74 0.012
cellular response to starvation GO:0009267 1 0.012
neuronal action potential GO:0019228 18 0.012
cell matrix adhesion GO:0007160 4 0.012
regulation of binding GO:0051098 3 0.012
negative regulation of gene expression GO:0010629 65 0.012
response to uv GO:0009411 3 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
sensory perception of pain GO:0019233 1 0.012
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.012
multi organism cellular process GO:0044764 2 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
system process GO:0003008 185 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
cell part morphogenesis GO:0032990 246 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
response to metal ion GO:0010038 34 0.011
protein modification process GO:0036211 100 0.011
cellular response to radiation GO:0071478 4 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
positive regulation of blood circulation GO:1903524 2 0.011
meiotic nuclear division GO:0007126 4 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
wnt signaling pathway GO:0016055 80 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
regulation of apoptotic process GO:0042981 98 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
circadian behavior GO:0048512 5 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
protein dephosphorylation GO:0006470 3 0.011
heart process GO:0003015 71 0.011
regulation of peptidase activity GO:0052547 23 0.011
positive regulation of cellular process GO:0048522 201 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
cellular response to light stimulus GO:0071482 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
somite development GO:0061053 96 0.010
gastrulation GO:0007369 208 0.010
apoptotic process involved in development GO:1902742 2 0.010
gene expression GO:0010467 252 0.010
neurological system process GO:0050877 62 0.010
response to fibroblast growth factor GO:0071774 22 0.010
regulation of cytokine production GO:0001817 3 0.010
fin regeneration GO:0031101 51 0.010
positive regulation of epithelial cell differentiation GO:0030858 2 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
cellular response to nutrient levels GO:0031669 2 0.010

LOC100331484 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.021
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
neuropathy DOID:870 0 0.021
charcot marie tooth disease DOID:10595 0 0.021
charcot marie tooth disease type 4 DOID:0050541 0 0.021