Danio rerio

0 known processes

LOC557062

hypothetical protein LOC557062

LOC557062 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
actomyosin structure organization GO:0031032 53 0.293
larval development GO:0002164 2 0.177
aging GO:0007568 2 0.172
response to stress GO:0006950 263 0.148
cell projection morphogenesis GO:0048858 244 0.136
sequestering of metal ion GO:0051238 3 0.131
lipid storage GO:0019915 1 0.120
cation transmembrane transport GO:0098655 65 0.113
inorganic cation transmembrane transport GO:0098662 50 0.110
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.108
mitotic g2 dna damage checkpoint GO:0007095 3 0.100
muscle structure development GO:0061061 196 0.099
single organism transport GO:0044765 206 0.098
calcium ion transport into cytosol GO:0060402 3 0.097
regulation of sequestering of calcium ion GO:0051282 4 0.097
response to chemical GO:0042221 320 0.092
axonal defasciculation GO:0007414 2 0.091
mitotic dna integrity checkpoint GO:0044774 4 0.090
lateral line system development GO:0048925 76 0.083
transport GO:0006810 220 0.082
cytosolic calcium ion transport GO:0060401 3 0.080
ion transmembrane transport GO:0034220 91 0.080
inorganic ion transmembrane transport GO:0098660 57 0.075
regulation of nucleotide catabolic process GO:0030811 2 0.074
superoxide metabolic process GO:0006801 2 0.072
guanosine containing compound metabolic process GO:1901068 4 0.071
embryonic viscerocranium morphogenesis GO:0048703 52 0.071
axon guidance GO:0007411 86 0.068
adult behavior GO:0030534 2 0.067
regulation of cell morphogenesis GO:0022604 42 0.067
heart looping GO:0001947 94 0.066
cell surface receptor signaling pathway GO:0007166 325 0.066
muscle cell development GO:0055001 115 0.065
regulation of biological quality GO:0065008 263 0.064
mitotic g2 m transition checkpoint GO:0044818 3 0.064
establishment of localization GO:0051234 244 0.063
muscle cell differentiation GO:0042692 139 0.061
transmembrane transport GO:0055085 120 0.059
heart development GO:0007507 313 0.059
neuron development GO:0048666 262 0.058
positive regulation of biological process GO:0048518 253 0.057
sensory organ morphogenesis GO:0090596 200 0.057
actin mediated cell contraction GO:0070252 1 0.056
regulation of cell size GO:0008361 29 0.056
single organism organelle organization GO:1902589 199 0.056
regulation of cell communication GO:0010646 232 0.053
single organism localization GO:1902578 225 0.053
embryonic organ morphogenesis GO:0048562 274 0.053
striated muscle cell development GO:0055002 108 0.052
embryonic cranial skeleton morphogenesis GO:0048701 90 0.052
g2 dna damage checkpoint GO:0031572 3 0.049
nuclear import GO:0051170 3 0.049
regulation of multicellular organism growth GO:0040014 4 0.048
axon development GO:0061564 166 0.048
cellular protein catabolic process GO:0044257 4 0.048
muscle organ development GO:0007517 101 0.048
regulation of cell shape GO:0008360 1 0.047
chordate embryonic development GO:0043009 271 0.047
regulation of synapse assembly GO:0051963 3 0.047
proteasomal protein catabolic process GO:0010498 2 0.046
gtp catabolic process GO:0006184 2 0.045
positive regulation of cell adhesion GO:0045785 1 0.045
gtp metabolic process GO:0046039 4 0.045
taxis GO:0042330 109 0.045
small gtpase mediated signal transduction GO:0007264 8 0.043
modification dependent macromolecule catabolic process GO:0043632 3 0.043
regulation of cellular component organization GO:0051128 86 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.042
meiotic nuclear division GO:0007126 4 0.042
somite development GO:0061053 96 0.042
endothelial cell proliferation GO:0001935 11 0.042
extrinsic apoptotic signaling pathway GO:0097191 3 0.041
nucleobase containing small molecule metabolic process GO:0055086 32 0.041
regulation of heart contraction GO:0008016 32 0.040
protein dephosphorylation GO:0006470 3 0.040
head development GO:0060322 303 0.040
axon extension GO:0048675 45 0.040
cell growth GO:0016049 57 0.039
convergent extension involved in gastrulation GO:0060027 71 0.038
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.038
actin cytoskeleton organization GO:0030036 63 0.038
biological adhesion GO:0022610 40 0.038
response to external stimulus GO:0009605 264 0.038
mechanosensory behavior GO:0007638 2 0.038
cation transport GO:0006812 81 0.037
nuclear transport GO:0051169 4 0.037
heart contraction GO:0060047 71 0.037
ameboidal type cell migration GO:0001667 143 0.037
cell substrate adhesion GO:0031589 4 0.037
organonitrogen compound metabolic process GO:1901564 74 0.037
digestive tract development GO:0048565 265 0.037
skeletal muscle organ development GO:0060538 78 0.035
cell morphogenesis involved in differentiation GO:0000904 195 0.035
regulation of axonogenesis GO:0050770 32 0.035
mucopolysaccharide metabolic process GO:1903510 2 0.035
single organism nuclear import GO:1902593 3 0.034
sequestering of calcium ion GO:0051208 3 0.034
regulation of cytokine production GO:0001817 3 0.034
regulation of cellular response to oxidative stress GO:1900407 2 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.033
immune system development GO:0002520 191 0.033
morphogenesis of an epithelium GO:0002009 333 0.033
modification dependent protein catabolic process GO:0019941 3 0.033
sarcomere organization GO:0045214 26 0.032
neuron projection guidance GO:0097485 86 0.031
cellular component movement GO:0006928 335 0.031
ras protein signal transduction GO:0007265 7 0.030
water homeostasis GO:0030104 4 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
maintenance of location GO:0051235 4 0.030
peptidyl serine phosphorylation GO:0018105 1 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
skeletal system morphogenesis GO:0048705 102 0.030
protein targeting to nucleus GO:0044744 3 0.029
ribosomal small subunit biogenesis GO:0042274 2 0.029
pronuclear migration GO:0035046 1 0.029
single organism metabolic process GO:0044710 217 0.029
multicellular organism growth GO:0035264 4 0.029
neuron projection morphogenesis GO:0048812 161 0.028
positive regulation of apoptotic signaling pathway GO:2001235 1 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
regulation of synapse organization GO:0050807 3 0.028
oxoacid metabolic process GO:0043436 31 0.028
single organism behavior GO:0044708 24 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
cellular component assembly involved in morphogenesis GO:0010927 107 0.028
ion transport GO:0006811 114 0.028
regulation of purine nucleotide catabolic process GO:0033121 2 0.028
oocyte maturation GO:0001556 4 0.028
regulation of neurotransmitter transport GO:0051588 1 0.027
cell part morphogenesis GO:0032990 246 0.027
embryonic skeletal system morphogenesis GO:0048704 93 0.027
mitotic dna damage checkpoint GO:0044773 4 0.027
embryonic skeletal system development GO:0048706 97 0.027
negative regulation of sequestering of calcium ion GO:0051283 4 0.027
cellular component morphogenesis GO:0032989 336 0.027
gastrulation GO:0007369 208 0.026
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.026
atp catabolic process GO:0006200 4 0.026
release of sequestered calcium ion into cytosol GO:0051209 3 0.026
cellular component biogenesis GO:0044085 178 0.026
positive regulation of cytokine production GO:0001819 2 0.025
regulation of protein import into nucleus GO:0042306 2 0.025
somitogenesis GO:0001756 87 0.025
thermosensory behavior GO:0040040 1 0.025
cytokinesis GO:0000910 3 0.025
smooth muscle contraction GO:0006939 2 0.024
regulation of reproductive process GO:2000241 4 0.024
tube morphogenesis GO:0035239 349 0.024
axis specification GO:0009798 43 0.024
circulatory system process GO:0003013 87 0.024
regulation of autophagy GO:0010506 3 0.024
cell substrate adherens junction assembly GO:0007045 1 0.024
adherens junction organization GO:0034332 4 0.024
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.023
regulation of filopodium assembly GO:0051489 2 0.023
positive regulation of phospholipase c activity GO:0010863 1 0.023
macromolecular complex subunit organization GO:0043933 74 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
axonogenesis GO:0007409 152 0.022
cellular component assembly GO:0022607 170 0.022
angiogenesis GO:0001525 158 0.022
cell projection organization GO:0030030 284 0.022
cytoskeleton organization GO:0007010 96 0.022
intracellular signal transduction GO:0035556 85 0.022
ear development GO:0043583 127 0.022
system process GO:0003008 185 0.022
brain development GO:0007420 293 0.022
response to abiotic stimulus GO:0009628 122 0.022
positive regulation of catabolic process GO:0009896 4 0.022
regulation of muscle contraction GO:0006937 3 0.021
cell matrix adhesion GO:0007160 4 0.021
metal ion transport GO:0030001 58 0.021
regulation of gtp catabolic process GO:0033124 2 0.021
synaptic vesicle localization GO:0097479 1 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
eye development GO:0001654 277 0.020
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
regulation of wound healing GO:0061041 2 0.019
striated muscle tissue development GO:0014706 110 0.019
apoptotic signaling pathway GO:0097190 23 0.019
protein localization to nucleus GO:0034504 3 0.019
phosphatidylinositol mediated signaling GO:0048015 2 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
positive regulation of signaling GO:0023056 56 0.019
collagen fibril organization GO:0030199 1 0.019
neuromast development GO:0048884 46 0.018
regulation of signal transduction GO:0009966 225 0.018
convergent extension GO:0060026 118 0.018
microtubule based movement GO:0007018 33 0.018
protein import into nucleus GO:0006606 3 0.018
protein complex subunit organization GO:0071822 46 0.018
phagocytosis engulfment GO:0006911 1 0.018
aminoglycan metabolic process GO:0006022 9 0.018
regulation of signaling GO:0023051 235 0.018
positive regulation of transport GO:0051050 2 0.018
cellular ion homeostasis GO:0006873 17 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
single organism cell adhesion GO:0098602 29 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
meiotic cell cycle process GO:1903046 3 0.018
cell recognition GO:0008037 19 0.018
regulation of establishment of planar polarity GO:0090175 4 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
protein import GO:0017038 3 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
cell substrate junction assembly GO:0007044 2 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
oocyte differentiation GO:0009994 14 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
regulation of system process GO:0044057 40 0.017
small molecule metabolic process GO:0044281 77 0.017
regulation of intracellular protein transport GO:0033157 3 0.016
epithelial cell morphogenesis GO:0003382 2 0.016
cellular response to starvation GO:0009267 1 0.016
regulation of blood coagulation GO:0030193 1 0.016
neurological system process GO:0050877 62 0.016
rho protein signal transduction GO:0007266 5 0.016
amine metabolic process GO:0009308 2 0.016
organelle organization GO:0006996 227 0.016
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.016
autonomic nervous system development GO:0048483 19 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
digestive system development GO:0055123 289 0.016
neuron differentiation GO:0030182 353 0.016
cognition GO:0050890 1 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
lipid metabolic process GO:0006629 52 0.015
negative regulation of biological process GO:0048519 304 0.015
synaptic vesicle transport GO:0048489 1 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
b cell differentiation GO:0030183 1 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
homeostatic process GO:0042592 142 0.015
embryonic organ development GO:0048568 381 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
regulation of embryonic development GO:0045995 47 0.015
negative regulation of signal transduction GO:0009968 94 0.015
regulation of dendrite development GO:0050773 3 0.015
positive regulation of lipid metabolic process GO:0045834 1 0.014
establishment of localization in cell GO:0051649 77 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
neuron recognition GO:0008038 18 0.014
hindbrain development GO:0030902 91 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
motor neuron axon guidance GO:0008045 23 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
regulation of neurological system process GO:0031644 2 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
behavior GO:0007610 74 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
regulation of intracellular signal transduction GO:1902531 57 0.013
positive regulation of chromosome segregation GO:0051984 1 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
regulation of cell adhesion GO:0030155 15 0.013
negative regulation of neuron projection regeneration GO:0070571 4 0.013
developmental growth GO:0048589 166 0.013
organic acid metabolic process GO:0006082 31 0.013
regulation of rac protein signal transduction GO:0035020 1 0.013
protein metabolic process GO:0019538 183 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
cellular metal ion homeostasis GO:0006875 16 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of metabolic process GO:0019222 359 0.013
regulation of hemostasis GO:1900046 1 0.013
adherens junction assembly GO:0034333 1 0.013
single fertilization GO:0007338 3 0.013
cellular protein modification process GO:0006464 100 0.012
wnt signaling pathway GO:0016055 80 0.012
developmental cell growth GO:0048588 52 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
central nervous system development GO:0007417 387 0.012
response to amino acid GO:0043200 2 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
organophosphate metabolic process GO:0019637 37 0.012
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.012
cell migration GO:0016477 237 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
actin filament based process GO:0030029 64 0.012
vacuolar transport GO:0007034 2 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
cell death in response to oxidative stress GO:0036473 2 0.012
autophagy GO:0006914 4 0.012
action potential GO:0001508 19 0.012
female meiotic division GO:0007143 2 0.012
camera type eye morphogenesis GO:0048593 108 0.012
homologous chromosome segregation GO:0045143 1 0.012
tube closure GO:0060606 1 0.012
regulation of catalytic activity GO:0050790 55 0.011
lateral inhibition GO:0046331 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
ion homeostasis GO:0050801 41 0.011
regulation of growth rate GO:0040009 1 0.011
female sex differentiation GO:0046660 4 0.011
signal transduction GO:0007165 455 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
small molecule catabolic process GO:0044282 3 0.011
mitochondrion organization GO:0007005 4 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
myotome development GO:0061055 1 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
cell death GO:0008219 121 0.011
muscle contraction GO:0006936 18 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
regulation of axon extension GO:0030516 24 0.011
cell adhesion GO:0007155 40 0.011
cell morphogenesis GO:0000902 289 0.011
response to uv GO:0009411 3 0.011
regulation of apoptotic process GO:0042981 98 0.011
male meiosis GO:0007140 2 0.011
segmentation GO:0035282 97 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.011
cell maturation GO:0048469 23 0.011
b cell activation GO:0042113 2 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
regulation of cell differentiation GO:0045595 142 0.011
sensory organ development GO:0007423 393 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
oocyte development GO:0048599 14 0.010
cell killing GO:0001906 2 0.010
negative regulation of smoothened signaling pathway GO:0045879 6 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
chemical homeostasis GO:0048878 49 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
fatty acid biosynthetic process GO:0006633 4 0.010
inner ear morphogenesis GO:0042472 63 0.010
secondary metabolic process GO:0019748 3 0.010
regulation of nervous system development GO:0051960 90 0.010
cellular biosynthetic process GO:0044249 286 0.010
organic cyclic compound metabolic process GO:1901360 301 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
regulation of circadian rhythm GO:0042752 4 0.010
auditory receptor cell development GO:0060117 8 0.010
neuron projection extension GO:1990138 45 0.010
cell cycle GO:0007049 93 0.010
protein stabilization GO:0050821 2 0.010
regulation of localization GO:0032879 104 0.010
gastrulation with mouth forming second GO:0001702 44 0.010

LOC557062 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
immune system disease DOID:2914 0 0.010