Danio rerio

17 known processes

LOC560602

novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6)

LOC560602 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glucose import GO:0046323 2 0.942
cerebellum vasculature development GO:0061300 1 0.922
hexose transport GO:0008645 6 0.847
glucose transport GO:0015758 6 0.707
carbohydrate transport GO:0008643 13 0.699
transmembrane transport GO:0055085 120 0.663
anion transport GO:0006820 38 0.545
liver development GO:0001889 96 0.521
single organism transport GO:0044765 206 0.496
monosaccharide transport GO:0015749 6 0.468
negative regulation of cellular process GO:0048523 283 0.357
cellular response to nutrient levels GO:0031669 2 0.247
activation of immune response GO:0002253 9 0.231
epithelial cell development GO:0002064 42 0.195
hepaticobiliary system development GO:0061008 98 0.184
negative regulation of biological process GO:0048519 304 0.169
transport GO:0006810 220 0.157
establishment of localization GO:0051234 244 0.147
single organism localization GO:1902578 225 0.135
apoptotic process GO:0006915 116 0.128
regulation of apoptotic process GO:0042981 98 0.119
regulation of multicellular organismal process GO:0051239 277 0.111
cellular response to extracellular stimulus GO:0031668 2 0.105
response to abiotic stimulus GO:0009628 122 0.104
gland development GO:0048732 143 0.104
vasculature development GO:0001944 278 0.103
cellular response to external stimulus GO:0071496 2 0.091
cell death GO:0008219 121 0.090
response to carbohydrate GO:0009743 3 0.083
activation of mapk activity GO:0000187 3 0.081
negative regulation of programmed cell death GO:0043069 58 0.080
cellular component assembly GO:0022607 170 0.078
regulation of cell death GO:0010941 103 0.072
reactive nitrogen species metabolic process GO:2001057 0 0.072
response to chemical GO:0042221 320 0.070
regulation of cytokine production GO:0001817 3 0.069
cellular response to starvation GO:0009267 1 0.066
death GO:0016265 121 0.064
endothelium development GO:0003158 25 0.063
response to stress GO:0006950 263 0.063
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.063
negative regulation of apoptotic process GO:0043066 55 0.061
regulation of inflammatory response GO:0050727 2 0.059
organic substance transport GO:0071702 58 0.059
complement activation GO:0006956 3 0.058
response to lipid GO:0033993 60 0.057
multicellular organismal metabolic process GO:0044236 2 0.055
response to external stimulus GO:0009605 264 0.055
positive regulation of cytokine production GO:0001819 2 0.054
response to osmotic stress GO:0006970 11 0.054
epithelial cell differentiation GO:0030855 116 0.052
regulation of production of molecular mediator of immune response GO:0002700 1 0.052
positive regulation of map kinase activity GO:0043406 3 0.051
regulation of macromolecule metabolic process GO:0060255 317 0.050
ion transport GO:0006811 114 0.050
regulation of programmed cell death GO:0043067 101 0.050
amine metabolic process GO:0009308 2 0.050
regulation of cellular amine metabolic process GO:0033238 0 0.049
regulation of reactive oxygen species metabolic process GO:2000377 2 0.046
response to hexose GO:0009746 3 0.046
signal transduction GO:0007165 455 0.045
cellular component biogenesis GO:0044085 178 0.044
response to glucocorticoid GO:0051384 1 0.043
aging GO:0007568 2 0.043
regulation of myeloid leukocyte differentiation GO:0002761 5 0.043
regulation of cellular amino acid metabolic process GO:0006521 0 0.043
programmed cell death GO:0012501 119 0.041
cellular amine metabolic process GO:0044106 2 0.041
larval development GO:0002164 2 0.040
positive regulation of cell activation GO:0050867 1 0.039
cellular response to organic substance GO:0071310 105 0.039
establishment of protein localization to plasma membrane GO:0090002 1 0.039
immune system process GO:0002376 241 0.039
cell surface receptor signaling pathway GO:0007166 325 0.038
regulation of cellular ketone metabolic process GO:0010565 7 0.038
g protein coupled receptor signaling pathway GO:0007186 74 0.038
regulation of developmental process GO:0050793 247 0.037
negative regulation of cell death GO:0060548 60 0.037
leukocyte proliferation GO:0070661 1 0.036
macromolecular complex subunit organization GO:0043933 74 0.035
cellular amino acid metabolic process GO:0006520 7 0.035
positive regulation of stress activated mapk cascade GO:0032874 3 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
protein activation cascade GO:0072376 6 0.034
organelle organization GO:0006996 227 0.034
response to alkaloid GO:0043279 2 0.032
reactive oxygen species metabolic process GO:0072593 6 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
regulation of metabolic process GO:0019222 359 0.032
regulation of primary metabolic process GO:0080090 311 0.032
organelle fusion GO:0048284 3 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
organic acid metabolic process GO:0006082 31 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.029
positive regulation of biological process GO:0048518 253 0.029
immunoglobulin mediated immune response GO:0016064 3 0.029
regulation of cellular metabolic process GO:0031323 320 0.028
negative regulation of myeloid cell differentiation GO:0045638 1 0.028
toll like receptor signaling pathway GO:0002224 4 0.028
response to organic cyclic compound GO:0014070 51 0.028
regulation of protein targeting GO:1903533 2 0.028
maintenance of location GO:0051235 4 0.027
superoxide metabolic process GO:0006801 2 0.027
regulation of erythrocyte differentiation GO:0045646 2 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.027
regulation of protein metabolic process GO:0051246 56 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.026
regulation of ph GO:0006885 3 0.026
interaction with host GO:0051701 4 0.026
response to glucose GO:0009749 3 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
positive regulation of translation GO:0045727 1 0.026
cellular component morphogenesis GO:0032989 336 0.026
response to monosaccharide GO:0034284 3 0.025
cellular response to biotic stimulus GO:0071216 3 0.025
hemopoiesis GO:0030097 183 0.025
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.025
endothelial cell development GO:0001885 12 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.025
negative regulation of leukocyte differentiation GO:1902106 1 0.024
neuron differentiation GO:0030182 353 0.024
b cell activation GO:0042113 2 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
antimicrobial humoral response GO:0019730 2 0.024
cellular response to lipopolysaccharide GO:0071222 3 0.024
sodium ion transmembrane transport GO:0035725 21 0.024
regulation of biological quality GO:0065008 263 0.024
protein localization to plasma membrane GO:0072659 1 0.023
myeloid cell homeostasis GO:0002262 56 0.023
regulation of homeostatic process GO:0032844 9 0.023
cellular ketone metabolic process GO:0042180 11 0.023
cognition GO:0050890 1 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
cellular response to stress GO:0033554 62 0.023
dicarboxylic acid metabolic process GO:0043648 1 0.023
positive regulation of immune effector process GO:0002699 3 0.023
response to corticosteroid GO:0031960 1 0.022
protein import into nucleus GO:0006606 3 0.022
head development GO:0060322 303 0.022
regulation of multicellular organismal metabolic process GO:0044246 2 0.022
negative regulation of cytokine production GO:0001818 1 0.022
response to nutrient GO:0007584 3 0.022
alpha amino acid metabolic process GO:1901605 3 0.022
response to drug GO:0042493 3 0.022
regulation of tube size GO:0035150 2 0.022
regulation of cell communication GO:0010646 232 0.022
establishment of blood brain barrier GO:0060856 2 0.021
regulation of synapse organization GO:0050807 3 0.021
positive regulation of jnk cascade GO:0046330 3 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
oxoacid metabolic process GO:0043436 31 0.021
regulation of cell activation GO:0050865 1 0.021
multicellular organism growth GO:0035264 4 0.020
protein localization to nucleus GO:0034504 3 0.020
atp catabolic process GO:0006200 4 0.020
regulation of reproductive process GO:2000241 4 0.020
cellular extravasation GO:0045123 1 0.020
generation of neurons GO:0048699 385 0.020
protein metabolic process GO:0019538 183 0.020
b cell mediated immunity GO:0019724 3 0.020
single organism nuclear import GO:1902593 3 0.020
response to starvation GO:0042594 5 0.020
muscle structure development GO:0061061 196 0.020
regulation of gene expression GO:0010468 265 0.020
mononuclear cell proliferation GO:0032943 1 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
response to oxygen containing compound GO:1901700 55 0.020
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.019
determination of bilateral symmetry GO:0009855 204 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
regulation of response to stimulus GO:0048583 269 0.019
macromolecule modification GO:0043412 111 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
electron transport chain GO:0022900 2 0.019
determination of left right symmetry GO:0007368 179 0.019
regulation of jak stat cascade GO:0046425 3 0.019
regulation of signal transduction GO:0009966 225 0.019
cellular protein metabolic process GO:0044267 129 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.019
myeloid cell differentiation GO:0030099 86 0.018
nitric oxide biosynthetic process GO:0006809 2 0.018
cellular protein catabolic process GO:0044257 4 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
skeletal system development GO:0001501 181 0.018
autophagy GO:0006914 4 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
bicarbonate transport GO:0015701 4 0.018
reactive oxygen species biosynthetic process GO:1903409 1 0.018
striated muscle tissue development GO:0014706 110 0.018
nuclear transport GO:0051169 4 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
protein import GO:0017038 3 0.017
neuron development GO:0048666 262 0.017
cellular response to estrogen stimulus GO:0071391 24 0.017
central nervous system neuron differentiation GO:0021953 74 0.017
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.017
phagocytosis GO:0006909 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
homeostatic process GO:0042592 142 0.017
nuclear import GO:0051170 3 0.017
single organism metabolic process GO:0044710 217 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
tissue remodeling GO:0048771 4 0.017
ion transmembrane transport GO:0034220 91 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
macromolecular complex assembly GO:0065003 35 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
neuroblast proliferation GO:0007405 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
inflammatory response GO:0006954 8 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
cation transport GO:0006812 81 0.016
rna localization GO:0006403 4 0.016
response to external biotic stimulus GO:0043207 97 0.016
positive regulation of inflammatory response GO:0050729 1 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.015
multi organism process GO:0051704 134 0.015
regulation of cell shape GO:0008360 1 0.015
monoamine transport GO:0015844 1 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
lymphocyte proliferation GO:0046651 1 0.015
positive regulation of transport GO:0051050 2 0.015
regulation of cell differentiation GO:0045595 142 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
regulation of synapse assembly GO:0051963 3 0.015
regulation of signaling GO:0023051 235 0.015
regulation of protein transport GO:0051223 3 0.015
positive regulation of jak stat cascade GO:0046427 2 0.015
protein polyubiquitination GO:0000209 4 0.015
cell morphogenesis GO:0000902 289 0.015
protein dephosphorylation GO:0006470 3 0.015
immune system development GO:0002520 191 0.014
inner ear morphogenesis GO:0042472 63 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
negative regulation of defense response GO:0031348 2 0.014
cell projection morphogenesis GO:0048858 244 0.014
response to endogenous stimulus GO:0009719 83 0.014
somatic stem cell maintenance GO:0035019 1 0.014
specification of symmetry GO:0009799 204 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
regulation of blood vessel size GO:0050880 2 0.014
carbon dioxide transport GO:0015670 3 0.014
cellular biosynthetic process GO:0044249 286 0.014
developmental growth GO:0048589 166 0.014
erythrocyte development GO:0048821 24 0.014
response to food GO:0032094 1 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
inorganic cation transmembrane transport GO:0098662 50 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
spermatid development GO:0007286 2 0.014
organism emergence from protective structure GO:0071684 4 0.014
cytokinesis GO:0000910 3 0.014
sensory perception of smell GO:0007608 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
single organism organelle organization GO:1902589 199 0.014
central nervous system development GO:0007417 387 0.014
heart looping GO:0001947 94 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
positive regulation of secretion GO:0051047 1 0.014
neuron projection extension GO:1990138 45 0.014
regulation of protein localization to nucleus GO:1900180 2 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
ear development GO:0043583 127 0.013
growth GO:0040007 174 0.013
immune response regulating signaling pathway GO:0002764 5 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
modification by symbiont of host morphology or physiology GO:0044003 4 0.013
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.013
response to vitamin GO:0033273 3 0.013
biosynthetic process GO:0009058 294 0.013
endothelial cell differentiation GO:0045446 20 0.013
regulation of proteolysis GO:0030162 24 0.013
cellular protein modification process GO:0006464 100 0.013
cell cycle g2 m phase transition GO:0044839 4 0.013
sodium ion import GO:0097369 3 0.013
pericardium development GO:0060039 1 0.013
adherens junction organization GO:0034332 4 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
protein secretion GO:0009306 1 0.013
gtp catabolic process GO:0006184 2 0.013
blood vessel development GO:0001568 246 0.013
axon development GO:0061564 166 0.013
actin mediated cell contraction GO:0070252 1 0.013
tube morphogenesis GO:0035239 349 0.013
protein acetylation GO:0006473 2 0.013
heart process GO:0003015 71 0.013
astrocyte differentiation GO:0048708 1 0.013
somite development GO:0061053 96 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
glial cell proliferation GO:0014009 4 0.013
semicircular canal development GO:0060872 24 0.013
defense response to other organism GO:0098542 33 0.013
cell part morphogenesis GO:0032990 246 0.013
regulation of muscle contraction GO:0006937 3 0.013
lipid storage GO:0019915 1 0.012
rna metabolic process GO:0016070 219 0.012
regulation of cellular ph GO:0030641 1 0.012
regulation of autophagy GO:0010506 3 0.012
swimming behavior GO:0036269 8 0.012
heart development GO:0007507 313 0.012
protein complex biogenesis GO:0070271 30 0.012
response to steroid hormone GO:0048545 35 0.012
organic substance biosynthetic process GO:1901576 289 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
positive regulation of gliogenesis GO:0014015 2 0.012
response to organic substance GO:0010033 153 0.012
wound healing GO:0042060 90 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
spermatid differentiation GO:0048515 2 0.012
positive regulation of cell cycle GO:0045787 3 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
response to nutrient levels GO:0031667 10 0.012
multicellular organismal response to stress GO:0033555 2 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
protein complex assembly GO:0006461 30 0.012
regulation of binding GO:0051098 3 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
response to wounding GO:0009611 116 0.012
cell projection organization GO:0030030 284 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
regulation of hormone secretion GO:0046883 2 0.012
negative regulation of kinase activity GO:0033673 4 0.012
negative regulation of immune response GO:0050777 2 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
embryonic heart tube development GO:0035050 133 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
membrane fusion GO:0061025 2 0.012
regulation of wound healing GO:0061041 2 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
regulation of protein catabolic process GO:0042176 1 0.011
stem cell maintenance GO:0019827 4 0.011
peptide transport GO:0015833 1 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
b cell differentiation GO:0030183 1 0.011
nitric oxide metabolic process GO:0046209 2 0.011
system process GO:0003008 185 0.011
regulation of glucose transport GO:0010827 1 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
one carbon compound transport GO:0019755 14 0.011
negative regulation of metabolic process GO:0009892 86 0.011
organic anion transport GO:0015711 15 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
water homeostasis GO:0030104 4 0.011
gene expression GO:0010467 252 0.011
blood vessel morphogenesis GO:0048514 216 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
cell matrix adhesion GO:0007160 4 0.011
response to nitrogen compound GO:1901698 19 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
cytoskeleton organization GO:0007010 96 0.011
protein stabilization GO:0050821 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
intracellular signal transduction GO:0035556 85 0.011
heart contraction GO:0060047 71 0.011
regulation of lipid transport GO:0032368 4 0.011
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
branched chain amino acid metabolic process GO:0009081 1 0.011
angiogenesis GO:0001525 158 0.011
actin cytoskeleton organization GO:0030036 63 0.011
long chain fatty acid biosynthetic process GO:0042759 1 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
gastrulation GO:0007369 208 0.011
protein complex subunit organization GO:0071822 46 0.011
developmental cell growth GO:0048588 52 0.011
somatic cell dna recombination GO:0016444 1 0.011
cell adhesion mediated by integrin GO:0033627 1 0.011
apical junction assembly GO:0043297 1 0.010
blood circulation GO:0008015 87 0.010
regulation of peptidase activity GO:0052547 23 0.010
tyrosine phosphorylation of stat protein GO:0007260 1 0.010
rna biosynthetic process GO:0032774 181 0.010
single organism membrane fusion GO:0044801 2 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
insulin like growth factor receptor signaling pathway GO:0048009 4 0.010
gtp metabolic process GO:0046039 4 0.010
centrosome organization GO:0051297 1 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of glucose import GO:0046324 1 0.010
cell migration GO:0016477 237 0.010
epidermal cell fate specification GO:0009957 4 0.010
sensory perception of pain GO:0019233 1 0.010
synaptic transmission cholinergic GO:0007271 4 0.010
sarcomere organization GO:0045214 26 0.010
regulation of mrna processing GO:0050684 3 0.010
modification of morphology or physiology of other organism GO:0035821 4 0.010
positive regulation of programmed cell death GO:0043068 29 0.010
metencephalon development GO:0022037 27 0.010
spinal cord motor neuron differentiation GO:0021522 26 0.010

LOC560602 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 0 0.428
idiopathic generalized epilepsy DOID:1827 0 0.428
central nervous system disease DOID:331 0 0.428
brain disease DOID:936 0 0.428
disease of anatomical entity DOID:7 0 0.428
nervous system disease DOID:863 0 0.428
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
eye disease DOID:5614 0 0.023
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
organ system cancer DOID:0050686 0 0.012