Danio rerio

0 known processes

LOC568379

von Willebrand factor A domain-containing protein 1-like

LOC568379 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.124
response to external stimulus GO:0009605 264 0.097
vasculature development GO:0001944 278 0.076
cellular protein catabolic process GO:0044257 4 0.072
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.067
regulation of protein targeting GO:1903533 2 0.065
regulation of cell communication GO:0010646 232 0.063
response to abiotic stimulus GO:0009628 122 0.063
blood vessel development GO:0001568 246 0.058
negative regulation of cellular process GO:0048523 283 0.056
regulation of protein catabolic process GO:0042176 1 0.055
response to external biotic stimulus GO:0043207 97 0.052
blood vessel morphogenesis GO:0048514 216 0.048
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.048
modification dependent protein catabolic process GO:0019941 3 0.047
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.047
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.045
growth GO:0040007 174 0.045
heart development GO:0007507 313 0.043
regulation of biological quality GO:0065008 263 0.043
signal transduction GO:0007165 455 0.043
proteasomal protein catabolic process GO:0010498 2 0.042
regulation of signal transduction GO:0009966 225 0.042
modification dependent macromolecule catabolic process GO:0043632 3 0.041
kidney development GO:0001822 92 0.041
amine metabolic process GO:0009308 2 0.040
response to alkaloid GO:0043279 2 0.038
negative regulation of signaling GO:0023057 96 0.038
skeletal system development GO:0001501 181 0.036
heart morphogenesis GO:0003007 156 0.035
protein complex subunit organization GO:0071822 46 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.034
regulation of multicellular organismal process GO:0051239 277 0.034
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.034
negative regulation of biological process GO:0048519 304 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
cellular amine metabolic process GO:0044106 2 0.033
regulation of epithelial cell proliferation GO:0050678 3 0.032
organonitrogen compound metabolic process GO:1901564 74 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.031
regulation of cellular protein catabolic process GO:1903362 1 0.031
skeletal system morphogenesis GO:0048705 102 0.031
regulation of cellular metabolic process GO:0031323 320 0.030
meiotic nuclear division GO:0007126 4 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
connective tissue development GO:0061448 99 0.029
heterocycle biosynthetic process GO:0018130 215 0.028
glucocorticoid metabolic process GO:0008211 2 0.028
embryonic organ morphogenesis GO:0048562 274 0.028
cellular ketone metabolic process GO:0042180 11 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
cytoskeleton dependent cytokinesis GO:0061640 3 0.027
positive regulation of cytokine production GO:0001819 2 0.026
multi organism process GO:0051704 134 0.026
cellular response to endogenous stimulus GO:0071495 68 0.026
cellular response to organic substance GO:0071310 105 0.026
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.026
embryonic organ development GO:0048568 381 0.025
angiogenesis GO:0001525 158 0.025
mitochondrion organization GO:0007005 4 0.025
negative regulation of response to stimulus GO:0048585 104 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
cell morphogenesis GO:0000902 289 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
protein homooligomerization GO:0051260 3 0.023
regulation of gene expression GO:0010468 265 0.023
protein import GO:0017038 3 0.023
muscle cell migration GO:0014812 4 0.022
sensory organ development GO:0007423 393 0.022
positive regulation of transport GO:0051050 2 0.022
aging GO:0007568 2 0.022
mesenchyme development GO:0060485 127 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.021
protein metabolic process GO:0019538 183 0.020
chordate embryonic development GO:0043009 271 0.020
response to virus GO:0009615 21 0.020
response to drug GO:0042493 3 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
maintenance of location GO:0051235 4 0.019
response to organic substance GO:0010033 153 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
cell migration GO:0016477 237 0.019
response to corticosteroid GO:0031960 1 0.019
urogenital system development GO:0001655 97 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
multicellular organism growth GO:0035264 4 0.018
protein localization to nucleus GO:0034504 3 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
kidney vasculature development GO:0061440 2 0.018
eye development GO:0001654 277 0.018
negative regulation of multicellular organismal process GO:0051241 69 0.018
neuron differentiation GO:0030182 353 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.018
regulation of protein transport GO:0051223 3 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
regulation of developmental process GO:0050793 247 0.017
embryonic skeletal system development GO:0048706 97 0.017
growth plate cartilage development GO:0003417 2 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of gtpase activity GO:0043087 2 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of mesenchymal cell proliferation GO:0010464 1 0.016
response to stress GO:0006950 263 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of bmp signaling pathway GO:0030510 39 0.016
central nervous system development GO:0007417 387 0.016
positive regulation of biological process GO:0048518 253 0.015
proteoglycan metabolic process GO:0006029 14 0.015
biosynthetic process GO:0009058 294 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
regulation of inflammatory response GO:0050727 2 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
fin development GO:0033333 77 0.015
regulation of metabolic process GO:0019222 359 0.015
regulation of response to stimulus GO:0048583 269 0.015
cartilage development GO:0051216 96 0.015
notochord development GO:0030903 54 0.014
oxoacid metabolic process GO:0043436 31 0.014
bmp signaling pathway GO:0030509 52 0.014
locomotion GO:0040011 313 0.014
proteolysis GO:0006508 38 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
death GO:0016265 121 0.014
nephron development GO:0072006 31 0.014
small molecule metabolic process GO:0044281 77 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
organ regeneration GO:0031100 1 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
renal system vasculature development GO:0061437 2 0.014
response to organic cyclic compound GO:0014070 51 0.014
nuclear migration GO:0007097 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
mitotic cytokinesis GO:0000281 3 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
cell part morphogenesis GO:0032990 246 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
nitrogen compound metabolic process GO:0006807 319 0.013
negative regulation of signal transduction GO:0009968 94 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
embryonic viscerocranium morphogenesis GO:0048703 52 0.013
negative regulation of catabolic process GO:0009895 3 0.013
response to chemical GO:0042221 320 0.013
regulation of response to external stimulus GO:0032101 31 0.013
regulation of cytokine production GO:0001817 3 0.013
regulation of cellular component movement GO:0051270 55 0.013
er nucleus signaling pathway GO:0006984 2 0.013
sequestering of metal ion GO:0051238 3 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
regulation of chemotaxis GO:0050920 18 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
glomerulus vasculature development GO:0072012 2 0.012
response to ketone GO:1901654 1 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
rna biosynthetic process GO:0032774 181 0.012
cellular catabolic process GO:0044248 27 0.012
response to endogenous stimulus GO:0009719 83 0.012
epithelial cell differentiation GO:0030855 116 0.012
negative regulation of cell communication GO:0010648 96 0.012
collagen fibril organization GO:0030199 1 0.012
cell aging GO:0007569 2 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
heterocycle metabolic process GO:0046483 290 0.011
renal system development GO:0072001 94 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
nuclear transport GO:0051169 4 0.011
positive regulation of reproductive process GO:2000243 2 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
extracellular matrix organization GO:0030198 27 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
muscle organ development GO:0007517 101 0.011
specification of symmetry GO:0009799 204 0.011
extracellular structure organization GO:0043062 27 0.011
axis elongation GO:0003401 31 0.011
taxis GO:0042330 109 0.011
establishment of localization GO:0051234 244 0.011
nephron morphogenesis GO:0072028 2 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
developmental growth GO:0048589 166 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
cell motility GO:0048870 244 0.010
response to biotic stimulus GO:0009607 97 0.010
heart contraction GO:0060047 71 0.010
response to vitamin GO:0033273 3 0.010
camera type eye development GO:0043010 222 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
single organism metabolic process GO:0044710 217 0.010
appendage morphogenesis GO:0035107 56 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
protein targeting to membrane GO:0006612 1 0.010
transport GO:0006810 220 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
mesenchymal cell differentiation GO:0048762 87 0.010

LOC568379 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.018
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
myopathy DOID:423 0 0.015
nervous system disease DOID:863 0 0.012