Danio rerio

0 known processes

LOC570775

protein argonaute-1-like

LOC570775 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cognition GO:0050890 1 0.589
response to dsrna GO:0043331 7 0.251
zinc ion transport GO:0006829 2 0.231
gene silencing by mirna GO:0035195 3 0.204
central nervous system development GO:0007417 387 0.200
striated muscle tissue development GO:0014706 110 0.199
germ line stem cell maintenance GO:0030718 2 0.193
regionalization GO:0003002 274 0.137
metal ion transport GO:0030001 58 0.130
gene expression GO:0010467 252 0.122
transmembrane transport GO:0055085 120 0.117
aromatic compound biosynthetic process GO:0019438 217 0.105
multicellular organism growth GO:0035264 4 0.097
regulation of multicellular organism growth GO:0040014 4 0.093
mrna metabolic process GO:0016071 20 0.092
regulation of metabolic process GO:0019222 359 0.092
potassium ion transmembrane transport GO:0071805 10 0.090
cellular response to dsrna GO:0071359 1 0.088
regulation of nitrogen compound metabolic process GO:0051171 251 0.087
regulation of wound healing GO:0061041 2 0.087
ion transport GO:0006811 114 0.084
brain development GO:0007420 293 0.078
aging GO:0007568 2 0.075
cation transport GO:0006812 81 0.074
cellular nitrogen compound metabolic process GO:0034641 290 0.068
segment polarity determination GO:0007367 1 0.065
microtubule organizing center organization GO:0031023 1 0.063
larval development GO:0002164 2 0.062
cellular macromolecule metabolic process GO:0044260 391 0.062
transport GO:0006810 220 0.061
nucleobase containing compound catabolic process GO:0034655 15 0.060
nitric oxide biosynthetic process GO:0006809 2 0.060
posttranscriptional gene silencing by rna GO:0035194 3 0.060
muscle cell development GO:0055001 115 0.060
gene silencing by rna GO:0031047 4 0.059
establishment of localization GO:0051234 244 0.059
ribosomal small subunit biogenesis GO:0042274 2 0.057
stem cell maintenance GO:0019827 4 0.057
myotube cell development GO:0014904 35 0.055
segmentation GO:0035282 97 0.055
mrna catabolic process GO:0006402 6 0.054
organic cyclic compound metabolic process GO:1901360 301 0.052
macromolecular complex subunit organization GO:0043933 74 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.051
heart looping GO:0001947 94 0.051
regulation of transmembrane transport GO:0034762 18 0.049
posttranscriptional gene silencing GO:0016441 3 0.048
heterocycle metabolic process GO:0046483 290 0.048
stem cell differentiation GO:0048863 117 0.048
nucleic acid metabolic process GO:0090304 244 0.048
regulation of macromolecule metabolic process GO:0060255 317 0.048
nitrogen compound metabolic process GO:0006807 319 0.047
rna processing GO:0006396 25 0.045
chordate embryonic development GO:0043009 271 0.045
monovalent inorganic cation transport GO:0015672 42 0.045
mrna cleavage GO:0006379 1 0.044
reactive oxygen species biosynthetic process GO:1903409 1 0.043
cellular response to nutrient levels GO:0031669 2 0.043
regulation of gene expression GO:0010468 265 0.042
muscle structure development GO:0061061 196 0.042
mrna cleavage involved in gene silencing by mirna GO:0035279 1 0.041
centrosome organization GO:0051297 1 0.041
meiotic nuclear division GO:0007126 4 0.040
neuron differentiation GO:0030182 353 0.040
single organism metabolic process GO:0044710 217 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.038
autophagy GO:0006914 4 0.037
somitogenesis GO:0001756 87 0.037
peptidyl serine modification GO:0018209 2 0.036
regulation of neurological system process GO:0031644 2 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
regulation of biological quality GO:0065008 263 0.036
positive regulation of transport GO:0051050 2 0.036
single organism nuclear import GO:1902593 3 0.036
morphogenesis of an epithelium GO:0002009 333 0.036
nuclear transport GO:0051169 4 0.036
response to nutrient GO:0007584 3 0.036
cellular response to extracellular stimulus GO:0031668 2 0.035
amine metabolic process GO:0009308 2 0.035
cellular component assembly GO:0022607 170 0.035
meiotic cell cycle process GO:1903046 3 0.034
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
nucleocytoplasmic transport GO:0006913 4 0.033
meiosis i GO:0007127 1 0.033
regulation of cellular metabolic process GO:0031323 320 0.033
anterior posterior pattern specification GO:0009952 152 0.032
positive regulation of cellular amine metabolic process GO:0033240 0 0.032
organic substance biosynthetic process GO:1901576 289 0.032
negative regulation of gene expression GO:0010629 65 0.032
gtp metabolic process GO:0046039 4 0.032
regulation of establishment of protein localization GO:0070201 4 0.031
organelle fusion GO:0048284 3 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
protein metabolic process GO:0019538 183 0.031
cellular protein metabolic process GO:0044267 129 0.031
peptidyl serine phosphorylation GO:0018105 1 0.031
digestive system development GO:0055123 289 0.030
negative regulation of biological process GO:0048519 304 0.030
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.030
generation of neurons GO:0048699 385 0.030
centrosome duplication GO:0051298 1 0.030
negative regulation of cellular process GO:0048523 283 0.030
single organism transport GO:0044765 206 0.030
embryo development ending in birth or egg hatching GO:0009792 271 0.030
adult behavior GO:0030534 2 0.029
regulation of response to stimulus GO:0048583 269 0.029
embryonic heart tube morphogenesis GO:0003143 108 0.029
determination of left right symmetry GO:0007368 179 0.029
small gtpase mediated signal transduction GO:0007264 8 0.029
cell aging GO:0007569 2 0.029
determination of heart left right asymmetry GO:0061371 117 0.029
positive regulation of cell cycle GO:0045787 3 0.028
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.028
protein localization to nucleus GO:0034504 3 0.028
organic cyclic compound catabolic process GO:1901361 15 0.028
head development GO:0060322 303 0.028
nuclear import GO:0051170 3 0.028
regulation of protein transport GO:0051223 3 0.028
cellular response to external stimulus GO:0071496 2 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
single organism localization GO:1902578 225 0.027
signal transduction GO:0007165 455 0.027
cellular amine metabolic process GO:0044106 2 0.027
hemopoiesis GO:0030097 183 0.027
somite development GO:0061053 96 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
embryonic heart tube development GO:0035050 133 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
alpha amino acid metabolic process GO:1901605 3 0.026
regulation of calcium ion transport GO:0051924 2 0.026
double strand break repair GO:0006302 3 0.026
mrna processing GO:0006397 14 0.026
cation transmembrane transport GO:0098655 65 0.026
cell volume homeostasis GO:0006884 1 0.026
protein import GO:0017038 3 0.026
regulation of metal ion transport GO:0010959 4 0.025
peptide transport GO:0015833 1 0.025
rna metabolic process GO:0016070 219 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
positive regulation of wound healing GO:0090303 1 0.025
lipid storage GO:0019915 1 0.025
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.025
cellular response to organic cyclic compound GO:0071407 38 0.025
periodic partitioning GO:0007365 1 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
protein targeting to nucleus GO:0044744 3 0.024
negative regulation of translation GO:0017148 1 0.024
cell substrate adhesion GO:0031589 4 0.024
g1 s transition of mitotic cell cycle GO:0000082 1 0.024
establishment of localization in cell GO:0051649 77 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
dna catabolic process GO:0006308 1 0.024
epithelial tube morphogenesis GO:0060562 148 0.024
digestive tract development GO:0048565 265 0.024
cellular component biogenesis GO:0044085 178 0.023
determination of bilateral symmetry GO:0009855 204 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
catabolic process GO:0009056 32 0.023
nitric oxide metabolic process GO:0046209 2 0.023
b cell differentiation GO:0030183 1 0.023
nucleic acid templated transcription GO:0097659 181 0.023
biosynthetic process GO:0009058 294 0.023
cellular macromolecule catabolic process GO:0044265 12 0.022
cellular nitrogen compound catabolic process GO:0044270 15 0.022
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.022
regulation of transcription dna templated GO:0006355 213 0.022
response to chemical GO:0042221 320 0.022
rna biosynthetic process GO:0032774 181 0.022
regulation of developmental process GO:0050793 247 0.022
neuromast development GO:0048884 46 0.022
zinc ion transmembrane transport GO:0071577 1 0.022
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
response to vitamin GO:0033273 3 0.021
negative regulation of ras protein signal transduction GO:0046580 1 0.021
transcription dna templated GO:0006351 181 0.021
digestive tract morphogenesis GO:0048546 231 0.021
cellular potassium ion transport GO:0071804 10 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
mitochondrion organization GO:0007005 4 0.021
gtp catabolic process GO:0006184 2 0.021
aromatic compound catabolic process GO:0019439 15 0.021
protein dephosphorylation GO:0006470 3 0.021
protein complex localization GO:0031503 1 0.021
gene silencing GO:0016458 4 0.020
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
transition metal ion transport GO:0000041 6 0.020
sprouting angiogenesis GO:0002040 53 0.020
negative regulation of kinase activity GO:0033673 4 0.020
regulation of carbohydrate metabolic process GO:0006109 4 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
centrosome cycle GO:0007098 1 0.020
gastrulation GO:0007369 208 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
maintenance of location GO:0051235 4 0.020
single organism membrane fusion GO:0044801 2 0.020
regulation of rna metabolic process GO:0051252 224 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
cellular response to organic substance GO:0071310 105 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
ribonucleoprotein complex biogenesis GO:0022613 13 0.019
sensory system development GO:0048880 76 0.019
skeletal muscle organ development GO:0060538 78 0.019
locomotion GO:0040011 313 0.019
organelle organization GO:0006996 227 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
regulation of mrna splicing via spliceosome GO:0048024 3 0.019
muscle tissue development GO:0060537 110 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
muscle fiber development GO:0048747 52 0.019
striated muscle cell differentiation GO:0051146 129 0.019
system process GO:0003008 185 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
regulation of dna templated transcription in response to stress GO:0043620 0 0.018
peptidyl threonine modification GO:0018210 1 0.018
pericardium development GO:0060039 1 0.018
regulation of gtpase activity GO:0043087 2 0.018
regulation of blood coagulation GO:0030193 1 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.018
regulation of transporter activity GO:0032409 2 0.018
cell matrix adhesion GO:0007160 4 0.018
ion transmembrane transport GO:0034220 91 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
potassium ion transport GO:0006813 10 0.017
heart development GO:0007507 313 0.017
negative regulation of transcription dna templated GO:0045892 45 0.017
response to organic cyclic compound GO:0014070 51 0.017
regulation of organelle assembly GO:1902115 4 0.017
regulation of cellular protein metabolic process GO:0032268 52 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
positive regulation of neuron death GO:1901216 1 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
heart contraction GO:0060047 71 0.017
secondary metabolic process GO:0019748 3 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
ras protein signal transduction GO:0007265 7 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
adherens junction organization GO:0034332 4 0.016
reproductive process GO:0022414 40 0.016
response to alkaloid GO:0043279 2 0.016
cellular biosynthetic process GO:0044249 286 0.016
apical junction assembly GO:0043297 1 0.016
chromosome organization involved in meiosis GO:0070192 1 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
skeletal muscle tissue development GO:0007519 67 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.016
pericardium morphogenesis GO:0003344 1 0.016
response to nitrogen compound GO:1901698 19 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.016
telomere organization GO:0032200 1 0.015
negative regulation of mrna metabolic process GO:1903312 3 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
regulation of gene expression epigenetic GO:0040029 11 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
translational initiation GO:0006413 3 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
estrogen metabolic process GO:0008210 2 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
hindbrain formation GO:0021576 3 0.015
b cell activation GO:0042113 2 0.015
synapsis GO:0007129 1 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
regulation of translational initiation GO:0006446 1 0.015
positive regulation of neuron apoptotic process GO:0043525 1 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
regulation of localization GO:0032879 104 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
peptidyl threonine phosphorylation GO:0018107 1 0.015
regulation of reproductive process GO:2000241 4 0.015
cellular ketone metabolic process GO:0042180 11 0.015
regulation of mrna processing GO:0050684 3 0.015
response to superoxide GO:0000303 2 0.015
histone phosphorylation GO:0016572 2 0.015
ameboidal type cell migration GO:0001667 143 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.014
spindle assembly GO:0051225 2 0.014
stem cell fate commitment GO:0048865 1 0.014
dsrna fragmentation GO:0031050 1 0.014
developmental growth GO:0048589 166 0.014
negative regulation of metabolic process GO:0009892 86 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
cellular response to starvation GO:0009267 1 0.014
negative regulation of rna biosynthetic process GO:1902679 45 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
positive regulation of catabolic process GO:0009896 4 0.014
rna catabolic process GO:0006401 7 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
cell morphogenesis GO:0000902 289 0.014
stem cell proliferation GO:0072089 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
vasculature development GO:0001944 278 0.014
positive regulation of secretion GO:0051047 1 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of ion transmembrane transport GO:0034765 18 0.014
multi organism process GO:0051704 134 0.014
protein import into nucleus GO:0006606 3 0.014
regulation of binding GO:0051098 3 0.014
regulation of cell differentiation GO:0045595 142 0.014
regulation of protein binding GO:0043393 3 0.014
negative regulation of cellular protein metabolic process GO:0032269 16 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
negative regulation of catabolic process GO:0009895 3 0.014
camera type eye development GO:0043010 222 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
intracellular signal transduction GO:0035556 85 0.014
muscle cell differentiation GO:0042692 139 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
negative regulation of protein metabolic process GO:0051248 16 0.013
regulation of hormone secretion GO:0046883 2 0.013
eye development GO:0001654 277 0.013
muscle organ development GO:0007517 101 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
establishment of rna localization GO:0051236 3 0.013
female germ line stem cell maintenance GO:0036099 1 0.013
regulation of protein targeting GO:1903533 2 0.013
dopamine biosynthetic process GO:0042416 2 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
protein acylation GO:0043543 3 0.013
positive regulation of ras protein signal transduction GO:0046579 1 0.013
gamete generation GO:0007276 33 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
hindbrain development GO:0030902 91 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
tube morphogenesis GO:0035239 349 0.013
regulation of protein complex assembly GO:0043254 3 0.013
positive regulation of epithelial cell migration GO:0010634 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
reactive oxygen species metabolic process GO:0072593 6 0.013
vacuolar transport GO:0007034 2 0.013
dopamine metabolic process GO:0042417 2 0.013
regulation of signaling GO:0023051 235 0.012
divalent inorganic cation homeostasis GO:0072507 22 0.012
positive regulation of endothelial cell migration GO:0010595 2 0.012
regulation of protein catabolic process GO:0042176 1 0.012
spermatid differentiation GO:0048515 2 0.012
telomere maintenance GO:0000723 1 0.012
hormone transport GO:0009914 2 0.012
chromosome organization GO:0051276 31 0.012
embryonic pattern specification GO:0009880 44 0.012
sensory organ development GO:0007423 393 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
protein acetylation GO:0006473 2 0.012
regulation of autophagy GO:0010506 3 0.012
posttranscriptional regulation of gene expression GO:0010608 14 0.012
lateral line development GO:0048882 66 0.012
positive regulation of cell activation GO:0050867 1 0.012
cellular response to oxygen levels GO:0071453 1 0.012
myotube differentiation GO:0014902 45 0.012
cellular chemical homeostasis GO:0055082 17 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
rna localization GO:0006403 4 0.012
superoxide metabolic process GO:0006801 2 0.012
nucleic acid transport GO:0050657 2 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
regulation of cellular response to oxidative stress GO:1900407 2 0.012
response to ketone GO:1901654 1 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
regulation of programmed cell death GO:0043067 101 0.012
regulation of biosynthetic process GO:0009889 250 0.011
positive regulation of cell division GO:0051781 2 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
heart morphogenesis GO:0003007 156 0.011
phagocytosis engulfment GO:0006911 1 0.011
positive regulation of translation GO:0045727 1 0.011
organic acid metabolic process GO:0006082 31 0.011
protein homooligomerization GO:0051260 3 0.011
regulation of cell activation GO:0050865 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
response to corticosteroid GO:0031960 1 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
type i interferon production GO:0032606 2 0.011
phagocytosis GO:0006909 3 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
regulation of synapse organization GO:0050807 3 0.011
response to organic substance GO:0010033 153 0.011
regulation of translation GO:0006417 3 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
ribonucleoprotein complex assembly GO:0022618 5 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
regulation of dna replication GO:0006275 3 0.011
protein polymerization GO:0051258 4 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
long chain fatty acid transport GO:0015909 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
negative regulation of map kinase activity GO:0043407 2 0.010
response to glucocorticoid GO:0051384 1 0.010
embryonic organ development GO:0048568 381 0.010
nuclear export GO:0051168 1 0.010
pigment granule organization GO:0048753 4 0.010
female sex differentiation GO:0046660 4 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
growth GO:0040007 174 0.010
positive regulation of immune effector process GO:0002699 3 0.010
long chain fatty acid metabolic process GO:0001676 1 0.010
cellular extravasation GO:0045123 1 0.010
programmed cell death GO:0012501 119 0.010
response to uv GO:0009411 3 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
regulation of signal transduction GO:0009966 225 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
pharyngeal muscle development GO:0043282 4 0.010
macroautophagy GO:0016236 1 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010

LOC570775 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone marrow disease DOID:4961 0 0.053
disease of anatomical entity DOID:7 0 0.053
immune system disease DOID:2914 0 0.053
hematopoietic system disease DOID:74 0 0.053
anemia DOID:2355 0 0.049
aplastic anemia DOID:12449 0 0.034
congenital hypoplastic anemia DOID:1342 0 0.034
fanconi s anemia DOID:13636 0 0.021
musculoskeletal system disease DOID:17 0 0.021
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.017
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.014
connective tissue disease DOID:65 0 0.011
organ system cancer DOID:0050686 0 0.011
muscular disease DOID:0080000 0 0.010
bone disease DOID:0080001 0 0.010
muscle tissue disease DOID:66 0 0.010
myopathy DOID:423 0 0.010