Danio rerio

0 known processes

acadm

acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain

(Aliases: wu:fb53e01,zgc:111905,zgc:56101,zgc:76911,fb53e01)

acadm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fatty acid beta oxidation GO:0006635 1 0.874
Human Mouse Rat
cellular respiration GO:0045333 3 0.676
small molecule catabolic process GO:0044282 3 0.671
Human Mouse Rat
carboxylic acid catabolic process GO:0046395 3 0.407
Human Mouse Rat
fatty acid catabolic process GO:0009062 1 0.370
Human Mouse Rat
respiratory electron transport chain GO:0022904 2 0.341
organic acid catabolic process GO:0016054 3 0.341
Human Mouse Rat
oxidation reduction process GO:0055114 41 0.288
Human Mouse Rat
cellular modified amino acid metabolic process GO:0006575 3 0.287
response to oxygen radical GO:0000305 2 0.285
response to transition metal nanoparticle GO:1990267 28 0.255
Rat
response to external biotic stimulus GO:0043207 97 0.218
cellular response to superoxide GO:0071451 2 0.202
oxoacid metabolic process GO:0043436 31 0.188
Human Mouse Rat
electron transport chain GO:0022900 2 0.177
hydrogen peroxide metabolic process GO:0042743 2 0.170
lipid oxidation GO:0034440 1 0.162
Human Mouse Rat
cellular response to oxygen radical GO:0071450 2 0.155
aging GO:0007568 2 0.134
response to superoxide GO:0000303 2 0.131
carboxylic acid metabolic process GO:0019752 22 0.129
Human Mouse Rat
atp synthesis coupled electron transport GO:0042773 1 0.124
larval development GO:0002164 2 0.119
lipid catabolic process GO:0016042 4 0.118
Human Mouse Rat
dicarboxylic acid metabolic process GO:0043648 1 0.112
regulation of cellular response to oxidative stress GO:1900407 2 0.110
small molecule metabolic process GO:0044281 77 0.108
Human Mouse Rat
response to bacterium GO:0009617 58 0.104
response to drug GO:0042493 3 0.097
Rat
removal of superoxide radicals GO:0019430 2 0.097
regulation of reactive oxygen species metabolic process GO:2000377 2 0.095
response to other organism GO:0051707 97 0.093
organonitrogen compound metabolic process GO:1901564 74 0.090
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.090
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.088
lipid storage GO:0019915 1 0.084
superoxide metabolic process GO:0006801 2 0.083
cell death in response to oxidative stress GO:0036473 2 0.082
regulation of rac protein signal transduction GO:0035020 1 0.081
cellular amide metabolic process GO:0043603 4 0.078
organic acid metabolic process GO:0006082 31 0.075
Human Mouse Rat
response to chemical GO:0042221 320 0.074
Rat
reactive oxygen species biosynthetic process GO:1903409 1 0.073
regulation of response to oxidative stress GO:1902882 2 0.069
cellular lipid catabolic process GO:0044242 3 0.069
Human Mouse Rat
response to hydrogen peroxide GO:0042542 3 0.067
fatty acid oxidation GO:0019395 1 0.066
Human Mouse Rat
cellular ketone metabolic process GO:0042180 11 0.064
Mouse
generation of precursor metabolites and energy GO:0006091 5 0.063
Mouse
autophagy GO:0006914 4 0.062
energy derivation by oxidation of organic compounds GO:0015980 5 0.060
Mouse
peptide metabolic process GO:0006518 1 0.060
regulation of multicellular organism growth GO:0040014 4 0.058
monocarboxylic acid catabolic process GO:0072329 3 0.058
Human Mouse Rat
maintenance of location GO:0051235 4 0.055
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.055
regulation of autophagy GO:0010506 3 0.050
mitochondrion organization GO:0007005 4 0.050
cellular amino acid metabolic process GO:0006520 7 0.050
regulation of intracellular ph GO:0051453 1 0.050
female gonad development GO:0008585 4 0.048
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.047
regulation of programmed cell death GO:0043067 101 0.046
adult behavior GO:0030534 2 0.046
response to inorganic substance GO:0010035 38 0.045
Rat
regulation of oxidative stress induced cell death GO:1903201 2 0.045
multicellular organism growth GO:0035264 4 0.045
regulation of blood vessel size GO:0050880 2 0.043
cellular catabolic process GO:0044248 27 0.043
Human Mouse Rat
lipid metabolic process GO:0006629 52 0.042
Human Mouse Rat
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.042
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.041
cellular protein catabolic process GO:0044257 4 0.041
single organism metabolic process GO:0044710 217 0.041
Human Mouse Rat
regulation of tube size GO:0035150 2 0.040
response to glucocorticoid GO:0051384 1 0.040
Rat
protein homooligomerization GO:0051260 3 0.039
Rat
cellular component morphogenesis GO:0032989 336 0.039
iron ion homeostasis GO:0055072 4 0.038
positive regulation of apoptotic signaling pathway GO:2001235 1 0.038
liver development GO:0001889 96 0.037
Mouse
heterocycle metabolic process GO:0046483 290 0.036
apoptotic process GO:0006915 116 0.036
negative regulation of apoptotic process GO:0043066 55 0.035
response to uv GO:0009411 3 0.034
xenobiotic metabolic process GO:0006805 4 0.034
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.034
zinc ion homeostasis GO:0055069 1 0.034
cellular response to reactive oxygen species GO:0034614 2 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
regulation of dna templated transcription in response to stress GO:0043620 0 0.031
reactive oxygen species metabolic process GO:0072593 6 0.031
neuron development GO:0048666 262 0.031
positive regulation of cytokine production GO:0001819 2 0.031
response to xenobiotic stimulus GO:0009410 45 0.031
regulation of protein catabolic process GO:0042176 1 0.029
transport GO:0006810 220 0.029
protein acetylation GO:0006473 2 0.028
regulation of primary metabolic process GO:0080090 311 0.028
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.028
Human Mouse
negative regulation of kinase activity GO:0033673 4 0.027
regulation of apoptotic process GO:0042981 98 0.027
immune system process GO:0002376 241 0.026
nitrogen compound metabolic process GO:0006807 319 0.026
Human Mouse
establishment of localization GO:0051234 244 0.026
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.026
regulation of cytokine production GO:0001817 3 0.026
regulation of biological quality GO:0065008 263 0.026
response to biotic stimulus GO:0009607 97 0.026
modification dependent protein catabolic process GO:0019941 3 0.025
alpha amino acid metabolic process GO:1901605 3 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
cellular amino acid biosynthetic process GO:0008652 2 0.025
organelle fusion GO:0048284 3 0.024
response to metal ion GO:0010038 34 0.024
Rat
regulation of blood pressure GO:0008217 1 0.024
detection of chemical stimulus GO:0009593 4 0.024
alcohol biosynthetic process GO:0046165 2 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.023
death GO:0016265 121 0.023
negative regulation of intracellular transport GO:0032387 3 0.023
cell part morphogenesis GO:0032990 246 0.023
regulation of rho protein signal transduction GO:0035023 2 0.023
sensory organ development GO:0007423 393 0.023
regulation of membrane potential GO:0042391 23 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
cellular extravasation GO:0045123 1 0.023
cell death GO:0008219 121 0.023
negative regulation of mapk cascade GO:0043409 4 0.022
gene expression GO:0010467 252 0.022
regulation of muscle contraction GO:0006937 3 0.022
homeostasis of number of cells GO:0048872 62 0.022
cell aging GO:0007569 2 0.022
regulation of protein localization to nucleus GO:1900180 2 0.021
protein import GO:0017038 3 0.021
response to reactive oxygen species GO:0000302 5 0.021
mitochondrial transport GO:0006839 2 0.021
ovulation cycle GO:0042698 2 0.021
regulation of rna metabolic process GO:0051252 224 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
Human
guanosine containing compound metabolic process GO:1901068 4 0.021
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.021
organic substance biosynthetic process GO:1901576 289 0.021
Human Mouse
response to methylmercury GO:0051597 11 0.021
transmembrane transport GO:0055085 120 0.020
cellular response to xenobiotic stimulus GO:0071466 35 0.020
neuron differentiation GO:0030182 353 0.020
programmed cell death GO:0012501 119 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.020
development of primary female sexual characteristics GO:0046545 4 0.019
negative regulation of cell death GO:0060548 60 0.019
regulation of protein transport GO:0051223 3 0.019
multi organism process GO:0051704 134 0.019
reactive nitrogen species metabolic process GO:2001057 0 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
cellular biosynthetic process GO:0044249 286 0.019
Human Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
system process GO:0003008 185 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
stem cell maintenance GO:0019827 4 0.017
cellular component movement GO:0006928 335 0.017
cellular lipid metabolic process GO:0044255 36 0.017
Human Mouse Rat
organelle organization GO:0006996 227 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
cellular transition metal ion homeostasis GO:0046916 3 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
very long chain fatty acid metabolic process GO:0000038 4 0.017
leukocyte proliferation GO:0070661 1 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of gtpase activity GO:0043087 2 0.017
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.017
regulation of protein binding GO:0043393 3 0.017
gland development GO:0048732 143 0.017
Mouse
gtp catabolic process GO:0006184 2 0.017
positive regulation of transport GO:0051050 2 0.016
regulation of binding GO:0051098 3 0.016
biosynthetic process GO:0009058 294 0.016
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.016
response to corticosteroid GO:0031960 1 0.016
Rat
catechol containing compound metabolic process GO:0009712 2 0.016
activation of mapk activity GO:0000187 3 0.016
protein acylation GO:0043543 3 0.016
nitric oxide biosynthetic process GO:0006809 2 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of inflammatory response GO:0050727 2 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
heart development GO:0007507 313 0.015
Mouse
negative regulation of cytoplasmic transport GO:1903650 2 0.015
catecholamine metabolic process GO:0006584 2 0.015
cell projection organization GO:0030030 284 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.015
positive regulation of biological process GO:0048518 253 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.014
rna biosynthetic process GO:0032774 181 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
regulation of cell activation GO:0050865 1 0.014
protein sumoylation GO:0016925 2 0.014
single organism catabolic process GO:0044712 13 0.014
Human Mouse Rat
regulation of nucleotide catabolic process GO:0030811 2 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
secondary metabolic process GO:0019748 3 0.014
myeloid cell homeostasis GO:0002262 56 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
protein metabolic process GO:0019538 183 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
Mouse
atp catabolic process GO:0006200 4 0.014
pigmentation GO:0043473 85 0.014
neurotransmitter transport GO:0006836 2 0.014
neuron death GO:0070997 21 0.013
negative regulation of signal transduction GO:0009968 94 0.013
b cell differentiation GO:0030183 1 0.013
response to organic substance GO:0010033 153 0.013
Rat
regulation of transmembrane transporter activity GO:0022898 2 0.013
hepaticobiliary system development GO:0061008 98 0.013
Mouse
ovarian follicle development GO:0001541 2 0.013
locomotory behavior GO:0007626 34 0.013
response to copper ion GO:0046688 13 0.013
Rat
response to endogenous stimulus GO:0009719 83 0.013
Rat
establishment of protein localization to organelle GO:0072594 4 0.013
female sex differentiation GO:0046660 4 0.013
cell projection morphogenesis GO:0048858 244 0.013
positive regulation of leukocyte mediated immunity GO:0002705 1 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
regulation of response to nutrient levels GO:0032107 1 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
ph reduction GO:0045851 1 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of response to stimulus GO:0048583 269 0.012
protein stabilization GO:0050821 2 0.012
monocarboxylic acid metabolic process GO:0032787 17 0.012
Human Mouse Rat
morphogenesis of an epithelium GO:0002009 333 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
cellular aldehyde metabolic process GO:0006081 4 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
negative regulation of oxidative stress induced cell death GO:1903202 2 0.012
regulation of mitochondrion organization GO:0010821 1 0.012
protein polyubiquitination GO:0000209 4 0.012
negative regulation of muscle contraction GO:0045932 1 0.012
ovulation cycle process GO:0022602 2 0.012
detection of stimulus GO:0051606 29 0.011
organic hydroxy compound metabolic process GO:1901615 16 0.011
Human Mouse
regulation of transporter activity GO:0032409 2 0.011
oxidative phosphorylation GO:0006119 1 0.011
sensory organ morphogenesis GO:0090596 200 0.011
axon cargo transport GO:0008088 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
transcription dna templated GO:0006351 181 0.011
positive regulation of catabolic process GO:0009896 4 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
response to axon injury GO:0048678 14 0.011
regulation of jun kinase activity GO:0043506 3 0.011
cellular response to nutrient levels GO:0031669 2 0.011
catabolic process GO:0009056 32 0.011
Human Mouse Rat
mechanoreceptor differentiation GO:0042490 37 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
sequestering of metal ion GO:0051238 3 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
response to oxygen containing compound GO:1901700 55 0.011
nucleic acid templated transcription GO:0097659 181 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
synaptic vesicle transport GO:0048489 1 0.011
developmental growth GO:0048589 166 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
Mouse
single organism localization GO:1902578 225 0.011
cellular macromolecule metabolic process GO:0044260 391 0.010
Mouse
nucleocytoplasmic transport GO:0006913 4 0.010
er nucleus signaling pathway GO:0006984 2 0.010
regulation of cellular metabolic process GO:0031323 320 0.010
Mouse
cellular response to starvation GO:0009267 1 0.010
protein localization to plasma membrane GO:0072659 1 0.010
regulation of gene expression GO:0010468 265 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
blood circulation GO:0008015 87 0.010
phagocytosis GO:0006909 3 0.010
sequestering of calcium ion GO:0051208 3 0.010
amine metabolic process GO:0009308 2 0.010
regulation of cell death GO:0010941 103 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
negative regulation of map kinase activity GO:0043407 2 0.010

acadm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.113
cancer DOID:162 0 0.072
disease of cellular proliferation DOID:14566 0 0.072
central nervous system disease DOID:331 0 0.070
motor neuron disease DOID:231 0 0.070
neurodegenerative disease DOID:1289 0 0.070
nervous system disease DOID:863 0 0.070
amyotrophic lateral sclerosis DOID:332 0 0.070
disease of anatomical entity DOID:7 0 0.070
inherited metabolic disorder DOID:655 0 0.055
mitochondrial metabolism disease DOID:700 0 0.045
organ system cancer DOID:0050686 0 0.031
endocrine gland cancer DOID:170 0 0.023
synucleinopathy DOID:0050890 0 0.013
amino acid metabolic disorder DOID:9252 0 0.010