Danio rerio

0 known processes

aco2

aconitase 2, mitochondrial

(Aliases: wu:fc20c11,cb1017,wu:fb69g04,wu:fa10e03)

aco2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dicarboxylic acid metabolic process GO:0043648 1 0.745
larval development GO:0002164 2 0.591
Worm
aging GO:0007568 2 0.591
Worm
coenzyme biosynthetic process GO:0009108 2 0.421
cellular respiration GO:0045333 3 0.395
Human Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.352
Worm
electron transport chain GO:0022900 2 0.309
thioester biosynthetic process GO:0035384 1 0.298
respiratory electron transport chain GO:0022904 2 0.231
atp synthesis coupled electron transport GO:0042773 1 0.225
cofactor biosynthetic process GO:0051188 10 0.224
organic acid catabolic process GO:0016054 3 0.187
carboxylic acid catabolic process GO:0046395 3 0.175
mitochondrion organization GO:0007005 4 0.127
Yeast
pyruvate metabolic process GO:0006090 1 0.124
regulation of neural precursor cell proliferation GO:2000177 3 0.097
energy derivation by oxidation of organic compounds GO:0015980 5 0.095
Human Yeast
oxidation reduction process GO:0055114 41 0.094
Human Yeast
acyl coa biosynthetic process GO:0071616 1 0.083
single organism metabolic process GO:0044710 217 0.079
Human Yeast
mitochondrial transport GO:0006839 2 0.070
cellular component morphogenesis GO:0032989 336 0.068
transmembrane transport GO:0055085 120 0.063
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.061
negative regulation of cellular process GO:0048523 283 0.061
small molecule metabolic process GO:0044281 77 0.058
Human
nucleoside triphosphate biosynthetic process GO:0009142 2 0.056
inorganic cation transmembrane transport GO:0098662 50 0.056
organic acid metabolic process GO:0006082 31 0.053
Human
spermatid differentiation GO:0048515 2 0.052
apoptotic process GO:0006915 116 0.052
cellular component movement GO:0006928 335 0.052
spermatid development GO:0007286 2 0.051
multicellular organism growth GO:0035264 4 0.050
oxidative phosphorylation GO:0006119 1 0.050
organelle organization GO:0006996 227 0.049
Yeast
localization of cell GO:0051674 244 0.049
organic cyclic compound biosynthetic process GO:1901362 223 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.045
stem cell proliferation GO:0072089 4 0.044
ion transport GO:0006811 114 0.044
multi organism process GO:0051704 134 0.043
rna biosynthetic process GO:0032774 181 0.043
organic substance biosynthetic process GO:1901576 289 0.043
small molecule catabolic process GO:0044282 3 0.043
establishment of localization GO:0051234 244 0.042
cell motility GO:0048870 244 0.042
reactive oxygen species metabolic process GO:0072593 6 0.041
cellular biosynthetic process GO:0044249 286 0.041
carboxylic acid metabolic process GO:0019752 22 0.040
Human
phagocytosis GO:0006909 3 0.040
response to external stimulus GO:0009605 264 0.039
sulfur compound biosynthetic process GO:0044272 9 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.038
nucleobase containing compound metabolic process GO:0006139 274 0.036
lipid storage GO:0019915 1 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
single organism transport GO:0044765 206 0.036
alpha amino acid metabolic process GO:1901605 3 0.035
multi organism reproductive process GO:0044703 36 0.034
maintenance of location GO:0051235 4 0.034
nucleotide metabolic process GO:0009117 28 0.033
oxoacid metabolic process GO:0043436 31 0.033
Human
acyl coa metabolic process GO:0006637 1 0.032
sequestering of calcium ion GO:0051208 3 0.032
monovalent inorganic cation transport GO:0015672 42 0.031
cognition GO:0050890 1 0.031
cation transmembrane transport GO:0098655 65 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
cation transport GO:0006812 81 0.030
sexual reproduction GO:0019953 36 0.030
cellular component assembly involved in morphogenesis GO:0010927 107 0.030
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.030
cell migration GO:0016477 237 0.030
cellular component assembly GO:0022607 170 0.029
thioester metabolic process GO:0035383 1 0.029
lamellipodium organization GO:0097581 1 0.029
oogenesis GO:0048477 14 0.028
response to nutrient GO:0007584 3 0.028
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.028
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
lipid catabolic process GO:0016042 4 0.027
cofactor metabolic process GO:0051186 15 0.027
ion homeostasis GO:0050801 41 0.026
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.026
blood vessel development GO:0001568 246 0.026
sensory organ development GO:0007423 393 0.026
cell death GO:0008219 121 0.026
system process GO:0003008 185 0.025
ribonucleotide biosynthetic process GO:0009260 20 0.025
muscle cell development GO:0055001 115 0.025
germ cell development GO:0007281 22 0.024
generation of precursor metabolites and energy GO:0006091 5 0.023
Human Yeast
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.023
inorganic ion transmembrane transport GO:0098660 57 0.023
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
negative regulation of gene expression GO:0010629 65 0.023
Worm
regulation of sequestering of calcium ion GO:0051282 4 0.023
cellular response to nutrient levels GO:0031669 2 0.022
transport GO:0006810 220 0.022
cellular response to external stimulus GO:0071496 2 0.022
regulation of myotube differentiation GO:0010830 2 0.022
organophosphate metabolic process GO:0019637 37 0.022
regulation of protein complex assembly GO:0043254 3 0.022
single organism biosynthetic process GO:0044711 71 0.022
response to organic substance GO:0010033 153 0.021
cellular response to topologically incorrect protein GO:0035967 2 0.021
regulation of endothelial cell proliferation GO:0001936 1 0.021
atp catabolic process GO:0006200 4 0.021
pole plasm assembly GO:0007315 4 0.020
developmental growth GO:0048589 166 0.020
chemosensory behavior GO:0007635 1 0.019
biosynthetic process GO:0009058 294 0.019
single organism localization GO:1902578 225 0.019
brain development GO:0007420 293 0.019
ribonucleoside biosynthetic process GO:0042455 2 0.019
negative regulation of biological process GO:0048519 304 0.018
Worm
establishment of localization in cell GO:0051649 77 0.018
multicellular organism reproduction GO:0032504 35 0.018
nucleic acid transport GO:0050657 2 0.018
cellular component disassembly GO:0022411 1 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of biological quality GO:0065008 263 0.018
coenzyme metabolic process GO:0006732 5 0.018
striated muscle cell development GO:0055002 108 0.018
signal transduction GO:0007165 455 0.018
programmed cell death GO:0012501 119 0.017
phagocytosis engulfment GO:0006911 1 0.017
single organism organelle organization GO:1902589 199 0.017
rna transport GO:0050658 2 0.017
regulation of developmental process GO:0050793 247 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
adult behavior GO:0030534 2 0.017
heterocycle metabolic process GO:0046483 290 0.017
regulation of membrane potential GO:0042391 23 0.017
monocarboxylic acid metabolic process GO:0032787 17 0.016
behavior GO:0007610 74 0.016
negative regulation of multicellular organismal process GO:0051241 69 0.016
regulation of protein binding GO:0043393 3 0.016
organonitrogen compound biosynthetic process GO:1901566 47 0.016
regulation of cell shape GO:0008360 1 0.016
protein import into nucleus GO:0006606 3 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
nuclear transport GO:0051169 4 0.016
membrane repolarization GO:0086009 2 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
response to drug GO:0042493 3 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
digestive tract development GO:0048565 265 0.015
multicellular organismal metabolic process GO:0044236 2 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
regulation of rna metabolic process GO:0051252 224 0.015
negative regulation of sequestering of calcium ion GO:0051283 4 0.015
cytosolic calcium ion transport GO:0060401 3 0.015
cellular amino acid biosynthetic process GO:0008652 2 0.015
vasculature development GO:0001944 278 0.015
lamellipodium assembly GO:0030032 1 0.014
angiogenesis GO:0001525 158 0.014
regulation of response to stimulus GO:0048583 269 0.014
protein stabilization GO:0050821 2 0.014
regulation of reproductive process GO:2000241 4 0.014
regulation of metabolic process GO:0019222 359 0.014
Worm
cellular response to extracellular stimulus GO:0031668 2 0.014
acetyl coa metabolic process GO:0006084 1 0.014
response to stress GO:0006950 263 0.014
neurotransmitter transport GO:0006836 2 0.014
membrane invagination GO:0010324 1 0.014
macromolecular complex disassembly GO:0032984 1 0.014
sleep GO:0030431 1 0.014
generation of neurons GO:0048699 385 0.014
negative regulation of neural precursor cell proliferation GO:2000178 1 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
connective tissue development GO:0061448 99 0.013
rna localization GO:0006403 4 0.013
cellular lipid catabolic process GO:0044242 3 0.013
3 utr mediated mrna stabilization GO:0070935 3 0.013
protein depolymerization GO:0051261 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
regulation of blood pressure GO:0008217 1 0.013
locomotion GO:0040011 313 0.013
Worm
regulation of establishment of protein localization GO:0070201 4 0.013
cell part morphogenesis GO:0032990 246 0.013
fatty acid transport GO:0015908 1 0.013
response to glucose GO:0009749 3 0.013
determination of left right symmetry GO:0007368 179 0.013
cellular response to oxygen levels GO:0071453 1 0.013
organelle assembly GO:0070925 110 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
meiotic cell cycle process GO:1903046 3 0.013
death GO:0016265 121 0.013
amine metabolic process GO:0009308 2 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
regulation of cell projection assembly GO:0060491 4 0.013
gastrulation GO:0007369 208 0.013
branched chain amino acid metabolic process GO:0009081 1 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
negative regulation of kinase activity GO:0033673 4 0.013
response to chemical GO:0042221 320 0.012
actin filament polymerization GO:0030041 2 0.012
negative regulation of blood circulation GO:1903523 2 0.012
sulfur compound metabolic process GO:0006790 13 0.012
striated muscle cell differentiation GO:0051146 129 0.012
trabecula morphogenesis GO:0061383 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
embryonic organ development GO:0048568 381 0.012
cell aging GO:0007569 2 0.012
protein polymerization GO:0051258 4 0.012
regulation of protein catabolic process GO:0042176 1 0.012
reproductive process GO:0022414 40 0.012
Worm
single fertilization GO:0007338 3 0.012
regulation of neurological system process GO:0031644 2 0.012
positive regulation of secretion GO:0051047 1 0.012
phosphorylation GO:0016310 69 0.012
ion transmembrane transport GO:0034220 91 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
regulation of binding GO:0051098 3 0.012
protein complex disassembly GO:0043241 1 0.012
blood vessel morphogenesis GO:0048514 216 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
regulation of cellular component organization GO:0051128 86 0.012
notochord development GO:0030903 54 0.012
negative regulation of catabolic process GO:0009895 3 0.012
aromatic compound biosynthetic process GO:0019438 217 0.011
peptide transport GO:0015833 1 0.011
transcription dna templated GO:0006351 181 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
rna metabolic process GO:0016070 219 0.011
cellular component biogenesis GO:0044085 178 0.011
nucleoside biosynthetic process GO:0009163 2 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of transporter activity GO:0032409 2 0.011
regulation of gene expression GO:0010468 265 0.011
Worm
proton transport GO:0015992 7 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of calcium ion transport GO:0051924 2 0.011
cellular amine metabolic process GO:0044106 2 0.011
negative regulation of heart contraction GO:0045822 2 0.011
single organism nuclear import GO:1902593 3 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
regulation of cell communication GO:0010646 232 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
myofibril assembly GO:0030239 48 0.011
protein localization to nucleus GO:0034504 3 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
heart looping GO:0001947 94 0.011
digestive system development GO:0055123 289 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
hydrogen peroxide metabolic process GO:0042743 2 0.011
cellular response to hypoxia GO:0071456 1 0.011
nucleoside monophosphate metabolic process GO:0009123 6 0.011
intracellular transport GO:0046907 32 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of cardiac muscle contraction GO:0055117 2 0.011
establishment of rna localization GO:0051236 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
vesicle mediated transport GO:0016192 22 0.011
gene expression GO:0010467 252 0.011
Worm
negative regulation of mapk cascade GO:0043409 4 0.011
negative regulation of intracellular transport GO:0032387 3 0.010
cellular localization GO:0051641 97 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
neurotransmitter secretion GO:0007269 2 0.010
negative regulation of signal transduction GO:0009968 94 0.010
reproduction GO:0000003 40 0.010
Worm
neurological system process GO:0050877 62 0.010

aco2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.124
Human
disease of metabolism DOID:0014667 0 0.041
nervous system disease DOID:863 0 0.040
Human
musculoskeletal system disease DOID:17 0 0.026
disease of cellular proliferation DOID:14566 0 0.020
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020
inherited metabolic disorder DOID:655 0 0.018
cardiovascular system disease DOID:1287 0 0.017
heart disease DOID:114 0 0.017
eye and adnexa disease DOID:1492 0 0.015
sensory system disease DOID:0050155 0 0.015
cardiomyopathy DOID:0050700 0 0.014
muscular disease DOID:0080000 0 0.014
myopathy DOID:423 0 0.014
muscle tissue disease DOID:66 0 0.014
eye disease DOID:5614 0 0.013
retinal disease DOID:5679 0 0.013
mitochondrial metabolism disease DOID:700 0 0.013
endocrine gland cancer DOID:170 0 0.012