Danio rerio

0 known processes

actr2

ARP2 actin-related protein 2 homolog

(Aliases: hm:zeh1257,zgc:63719,actr2a)

actr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.463
Worm
positive regulation of cellular component biogenesis GO:0044089 3 0.278
Human Yeast Worm Fly
regulation of protein complex assembly GO:0043254 3 0.198
Human Yeast Worm
protein polymerization GO:0051258 4 0.196
Human Yeast Worm
regulation of biological quality GO:0065008 263 0.196
Human Yeast Worm Fly
regulation of protein polymerization GO:0032271 2 0.196
Human Yeast Worm
regulation of cell shape GO:0008360 1 0.105
cellular component biogenesis GO:0044085 178 0.097
Human Yeast Worm Fly
single organism metabolic process GO:0044710 217 0.084
Yeast
maintenance of location GO:0051235 4 0.081
positive regulation of protein complex assembly GO:0031334 2 0.079
Human Yeast Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.077
Worm
actin filament polymerization GO:0030041 2 0.077
Human Yeast Worm
signal transduction GO:0007165 455 0.075
sensory organ development GO:0007423 393 0.073
cellular macromolecular complex assembly GO:0034622 24 0.072
Human Yeast Worm
cell projection organization GO:0030030 284 0.065
Human Fly
amine metabolic process GO:0009308 2 0.061
spindle assembly GO:0051225 2 0.061
aging GO:0007568 2 0.058
establishment of localization GO:0051234 244 0.058
Yeast Mouse Worm
regulation of response to stimulus GO:0048583 269 0.056
single organism transport GO:0044765 206 0.056
Yeast Worm
nitrogen compound metabolic process GO:0006807 319 0.056
Yeast
cellular protein metabolic process GO:0044267 129 0.053
cellular amine metabolic process GO:0044106 2 0.053
nucleic acid metabolic process GO:0090304 244 0.050
transport GO:0006810 220 0.050
Yeast Mouse Worm
regulation of mrna splicing via spliceosome GO:0048024 3 0.048
neuron differentiation GO:0030182 353 0.047
cellular component assembly GO:0022607 170 0.047
Human Yeast Worm Fly
cytoskeleton organization GO:0007010 96 0.046
Human Yeast Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.046
Human Fly
organelle organization GO:0006996 227 0.046
Human Yeast Mouse Worm Fly
positive regulation of cytoskeleton organization GO:0051495 3 0.046
Human Yeast Worm
multicellular organism growth GO:0035264 4 0.045
regulation of multicellular organism growth GO:0040014 4 0.044
biosynthetic process GO:0009058 294 0.043
regulation of filopodium assembly GO:0051489 2 0.042
Fly
cortical actin cytoskeleton organization GO:0030866 1 0.042
golgi vesicle transport GO:0048193 3 0.041
cellular component morphogenesis GO:0032989 336 0.041
Human Yeast Fly
single organism membrane fusion GO:0044801 2 0.041
negative regulation of protein complex assembly GO:0031333 1 0.041
regulation of cell projection assembly GO:0060491 4 0.041
Fly
regulation of mrna processing GO:0050684 3 0.040
immune system process GO:0002376 241 0.040
positive regulation of transport GO:0051050 2 0.040
organelle fusion GO:0048284 3 0.040
nuclear transport GO:0051169 4 0.040
actin polymerization or depolymerization GO:0008154 2 0.038
Human Yeast Worm
cellular amino acid metabolic process GO:0006520 7 0.037
response to stress GO:0006950 263 0.036
cortical cytoskeleton organization GO:0030865 1 0.036
regulation of cell communication GO:0010646 232 0.036
cellular component disassembly GO:0022411 1 0.036
negative regulation of biological process GO:0048519 304 0.034
secondary metabolic process GO:0019748 3 0.034
organic acid metabolic process GO:0006082 31 0.034
actin cytoskeleton organization GO:0030036 63 0.034
Human Yeast Mouse Worm Fly
intracellular signal transduction GO:0035556 85 0.034
cell part morphogenesis GO:0032990 246 0.034
Human
oxoacid metabolic process GO:0043436 31 0.033
organic substance biosynthetic process GO:1901576 289 0.033
proteasomal protein catabolic process GO:0010498 2 0.033
negative regulation of cellular process GO:0048523 283 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
brain development GO:0007420 293 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.032
Yeast
protein targeting to nucleus GO:0044744 3 0.032
gtp metabolic process GO:0046039 4 0.032
single fertilization GO:0007338 3 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
nucleocytoplasmic transport GO:0006913 4 0.031
phagocytosis engulfment GO:0006911 1 0.031
Worm
positive regulation of biological process GO:0048518 253 0.031
Human Yeast Worm Fly
muscle structure development GO:0061061 196 0.030
lipid storage GO:0019915 1 0.030
positive regulation of cellular process GO:0048522 201 0.030
Human Yeast Worm Fly
modification dependent protein catabolic process GO:0019941 3 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
Yeast
membrane invagination GO:0010324 1 0.030
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.030
Yeast
regulation of reproductive process GO:2000241 4 0.029
small molecule metabolic process GO:0044281 77 0.029
Yeast
carboxylic acid metabolic process GO:0019752 22 0.029
death GO:0016265 121 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
organic cyclic compound metabolic process GO:1901360 301 0.028
Yeast
locomotion GO:0040011 313 0.028
Worm
homeostatic process GO:0042592 142 0.028
protein complex biogenesis GO:0070271 30 0.028
Human Yeast Worm
regulation of signaling GO:0023051 235 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
regulation of synaptic plasticity GO:0048167 1 0.028
centrosome organization GO:0051297 1 0.027
protein localization to nucleus GO:0034504 3 0.026
phagocytosis GO:0006909 3 0.026
Worm
cell adhesion mediated by integrin GO:0033627 1 0.026
chordate embryonic development GO:0043009 271 0.026
stem cell proliferation GO:0072089 4 0.025
cellular biosynthetic process GO:0044249 286 0.025
somatic muscle development GO:0007525 4 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
regulation of binding GO:0051098 3 0.025
actin filament based process GO:0030029 64 0.025
Human Yeast Mouse Worm Fly
multi organism process GO:0051704 134 0.025
Yeast
regulation of metabolic process GO:0019222 359 0.025
regulation of developmental process GO:0050793 247 0.025
Fly
regulation of cytoplasmic transport GO:1903649 4 0.024
cellular protein catabolic process GO:0044257 4 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
stem cell division GO:0017145 1 0.024
single organism nuclear import GO:1902593 3 0.024
protein import GO:0017038 3 0.024
cellular response to external stimulus GO:0071496 2 0.024
membrane fusion GO:0061025 2 0.024
heterocycle metabolic process GO:0046483 290 0.024
Yeast
response to external stimulus GO:0009605 264 0.024
regulation of localization GO:0032879 104 0.024
regulation of cellular component organization GO:0051128 86 0.024
Human Yeast Worm Fly
cellular macromolecule localization GO:0070727 21 0.023
Yeast
fertilization GO:0009566 3 0.023
wound healing GO:0042060 90 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
positive regulation of notch signaling pathway GO:0045747 3 0.023
cognition GO:0050890 1 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.022
meiotic cell cycle process GO:1903046 3 0.022
Yeast Mouse
regulation of multicellular organismal process GO:0051239 277 0.022
Fly
cell surface receptor signaling pathway GO:0007166 325 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
pigment metabolic process GO:0042440 12 0.022
alternative mrna splicing via spliceosome GO:0000380 1 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of cell morphogenesis GO:0022604 42 0.022
regulation of receptor mediated endocytosis GO:0048259 4 0.022
negative regulation of nuclear division GO:0051784 3 0.022
phosphate containing compound metabolic process GO:0006796 108 0.022
Yeast
cytoskeleton dependent cytokinesis GO:0061640 3 0.021
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.021
positive regulation of protein polymerization GO:0032273 2 0.021
Human Yeast Worm
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
defense response GO:0006952 47 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
embryonic organ development GO:0048568 381 0.021
regulation of protein catabolic process GO:0042176 1 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.021
apoptotic process GO:0006915 116 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
axonogenesis GO:0007409 152 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
regulation of primary metabolic process GO:0080090 311 0.020
positive regulation of catabolic process GO:0009896 4 0.020
rna metabolic process GO:0016070 219 0.020
regulation of signal transduction GO:0009966 225 0.020
protein n linked glycosylation GO:0006487 1 0.020
single organism organelle organization GO:1902589 199 0.020
Human Yeast Mouse Worm Fly
nuclear import GO:0051170 3 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
protein complex disassembly GO:0043241 1 0.020
vasculature development GO:0001944 278 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
macromolecule modification GO:0043412 111 0.019
rna biosynthetic process GO:0032774 181 0.019
system process GO:0003008 185 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
Yeast
ameboidal type cell migration GO:0001667 143 0.019
Worm
mitochondrion organization GO:0007005 4 0.019
Yeast
neuroblast proliferation GO:0007405 2 0.019
gene expression GO:0010467 252 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
protein import into nucleus GO:0006606 3 0.019
meiotic nuclear division GO:0007126 4 0.019
Mouse Worm
ras protein signal transduction GO:0007265 7 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
response to wounding GO:0009611 116 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
macromolecular complex disassembly GO:0032984 1 0.018
cell projection morphogenesis GO:0048858 244 0.018
Human
regulation of cellular amine metabolic process GO:0033238 0 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
head development GO:0060322 303 0.018
positive regulation of cell cycle GO:0045787 3 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
nuclear export GO:0051168 1 0.017
microtubule based process GO:0007017 60 0.017
Mouse
regulation of protein transport GO:0051223 3 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
Fly
localization of cell GO:0051674 244 0.017
Worm
adult behavior GO:0030534 2 0.017
regulation of translational initiation GO:0006446 1 0.017
tissue remodeling GO:0048771 4 0.017
cellular response to topologically incorrect protein GO:0035967 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
Worm
cell motility GO:0048870 244 0.017
Worm
eye development GO:0001654 277 0.017
regulation of synapse organization GO:0050807 3 0.017
Fly
peptide transport GO:0015833 1 0.017
protein localization to plasma membrane GO:0072659 1 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
cellular response to nutrient levels GO:0031669 2 0.016
neuron development GO:0048666 262 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
regulation of catalytic activity GO:0050790 55 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
negative regulation of organelle organization GO:0010639 4 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
Yeast
macromolecular complex assembly GO:0065003 35 0.016
Human Yeast Worm
gtp catabolic process GO:0006184 2 0.015
exocytosis GO:0006887 1 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
Yeast
muscle cell development GO:0055001 115 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
cellular response to starvation GO:0009267 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
protein heterooligomerization GO:0051291 1 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
tube closure GO:0060606 1 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
Human Yeast Worm Fly
regulation of cytokine production GO:0001817 3 0.015
cellular protein complex assembly GO:0043623 19 0.015
Human Yeast Worm
atp catabolic process GO:0006200 4 0.015
Yeast
behavior GO:0007610 74 0.014
generation of neurons GO:0048699 385 0.014
response to nutrient GO:0007584 3 0.014
rna localization GO:0006403 4 0.014
spindle assembly involved in mitosis GO:0090307 1 0.014
positive regulation of translation GO:0045727 1 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of protein targeting GO:1903533 2 0.014
protein dephosphorylation GO:0006470 3 0.014
protein metabolic process GO:0019538 183 0.014
cell cycle GO:0007049 93 0.014
Yeast Mouse Worm
regulation of cell activation GO:0050865 1 0.014
phosphorus metabolic process GO:0006793 109 0.014
Yeast
intracellular transport GO:0046907 32 0.014
Yeast Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
response to drug GO:0042493 3 0.014
lamellipodium organization GO:0097581 1 0.014
cilium morphogenesis GO:0060271 85 0.014
Human
cytokinesis GO:0000910 3 0.014
Mouse
defense response to other organism GO:0098542 33 0.014
post golgi vesicle mediated transport GO:0006892 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
negative regulation of kinase activity GO:0033673 4 0.013
cellular ketone metabolic process GO:0042180 11 0.013
post embryonic morphogenesis GO:0009886 4 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
striated muscle cell differentiation GO:0051146 129 0.013
compound eye development GO:0048749 2 0.013
chemical homeostasis GO:0048878 49 0.013
female sex differentiation GO:0046660 4 0.013
regulation of wound healing GO:0061041 2 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
Yeast
heart development GO:0007507 313 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
response to topologically incorrect protein GO:0035966 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
biological adhesion GO:0022610 40 0.013
regulation of protein localization to plasma membrane GO:1903076 1 0.013
mononuclear cell proliferation GO:0032943 1 0.013
lamellipodium assembly GO:0030032 1 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
response to chemical GO:0042221 320 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
regulation of gene expression GO:0010468 265 0.013
spermatid differentiation GO:0048515 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
embryonic skeletal system development GO:0048706 97 0.013
blood vessel development GO:0001568 246 0.013
somitogenesis GO:0001756 87 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
cell substrate adhesion GO:0031589 4 0.012
cellular amide metabolic process GO:0043603 4 0.012
pigment granule localization GO:0051875 25 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
negative regulation of protein transport GO:0051224 3 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of ph GO:0006885 3 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
endosomal transport GO:0016197 2 0.012
mitochondrial transport GO:0006839 2 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
cellular localization GO:0051641 97 0.012
Yeast Mouse
antimicrobial humoral response GO:0019730 2 0.012
skeletal system development GO:0001501 181 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of protein metabolic process GO:0051246 56 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
protein localization GO:0008104 40 0.012
Yeast
hematopoietic or lymphoid organ development GO:0048534 191 0.012
cellular biogenic amine metabolic process GO:0006576 2 0.012
neurotransmitter secretion GO:0007269 2 0.012
positive regulation of cell activation GO:0050867 1 0.011
neurological system process GO:0050877 62 0.011
macromolecule localization GO:0033036 54 0.011
Yeast
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
neurotransmitter transport GO:0006836 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
spermatid development GO:0007286 2 0.011
hormone secretion GO:0046879 2 0.011
positive regulation of reproductive process GO:2000243 2 0.011
synaptic vesicle transport GO:0048489 1 0.011
zinc ion homeostasis GO:0055069 1 0.011
central nervous system development GO:0007417 387 0.011
regulation of rna metabolic process GO:0051252 224 0.011
macroautophagy GO:0016236 1 0.011
establishment of rna localization GO:0051236 3 0.011
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
cell matrix adhesion GO:0007160 4 0.011
blood vessel morphogenesis GO:0048514 216 0.011
superoxide metabolic process GO:0006801 2 0.011
cell adhesion GO:0007155 40 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
response to monosaccharide GO:0034284 3 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
negative regulation of signaling GO:0023057 96 0.011
rna modification GO:0009451 2 0.011
peptide metabolic process GO:0006518 1 0.011
cellular protein modification process GO:0006464 100 0.011
ovulation cycle GO:0042698 2 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
somite development GO:0061053 96 0.011
protein stabilization GO:0050821 2 0.011
autophagy GO:0006914 4 0.011
female gonad development GO:0008585 4 0.011
b cell activation GO:0042113 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
mitotic cytokinesis GO:0000281 3 0.011
digestive system development GO:0055123 289 0.011
positive regulation of secretion GO:0051047 1 0.011
double strand break repair GO:0006302 3 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
cell death GO:0008219 121 0.011
renal tubule morphogenesis GO:0061333 1 0.010
urogenital system development GO:0001655 97 0.010
specification of axis polarity GO:0065001 4 0.010
cellular protein complex disassembly GO:0043624 1 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
leukocyte proliferation GO:0070661 1 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
response to hexose GO:0009746 3 0.010
programmed cell death GO:0012501 119 0.010
regulation of sodium ion transport GO:0002028 2 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
regulation of protein binding GO:0043393 3 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
germ line stem cell maintenance GO:0030718 2 0.010
gland development GO:0048732 143 0.010
actin filament based movement GO:0030048 1 0.010

actr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.148
disease of metabolism DOID:0014667 0 0.027
nervous system disease DOID:863 0 0.023
inherited metabolic disorder DOID:655 0 0.022
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
sensory system disease DOID:0050155 0 0.017
immune system disease DOID:2914 0 0.012
primary immunodeficiency disease DOID:612 0 0.012
muscle tissue disease DOID:66 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscular disease DOID:0080000 0 0.010