Danio rerio

39 known processes

acvr2a

activin receptor IIa

(Aliases: acvr2,wu:fa02e10,actr2a)

acvr2a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hormone mediated signaling pathway GO:0009755 9 0.712
lymphatic endothelial cell differentiation GO:0060836 1 0.711
regulation of biological quality GO:0065008 263 0.685
Human Rat
positive regulation of biological process GO:0048518 253 0.630
Human Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.602
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.600
Human Mouse Rat
organic substance biosynthetic process GO:1901576 289 0.596
Human Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.578
cellular aromatic compound metabolic process GO:0006725 295 0.573
Human Mouse
regulation of primary metabolic process GO:0080090 311 0.564
Human Mouse
negative regulation of biological process GO:0048519 304 0.557
aging GO:0007568 2 0.547
steroid hormone secretion GO:0035929 1 0.534
organic cyclic compound metabolic process GO:1901360 301 0.506
Human Mouse
cellular biosynthetic process GO:0044249 286 0.505
Human Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.492
central nervous system development GO:0007417 387 0.492
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.490
aromatic compound biosynthetic process GO:0019438 217 0.483
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.460
Human Mouse
hormone secretion GO:0046879 2 0.436
Rat
response to external stimulus GO:0009605 264 0.423
regulation of nitrogen compound metabolic process GO:0051171 251 0.416
Human Mouse
endocrine hormone secretion GO:0060986 2 0.407
Rat
regulation of cell communication GO:0010646 232 0.389
Human Mouse Rat
heterocycle metabolic process GO:0046483 290 0.385
Human Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.378
regulation of cellular metabolic process GO:0031323 320 0.368
Human Mouse
response to chemical GO:0042221 320 0.367
Human Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.362
Human Mouse
pathway restricted smad protein phosphorylation GO:0060389 1 0.354
Human
regulation of hormone secretion GO:0046883 2 0.340
Rat
positive regulation of secretion by cell GO:1903532 1 0.338
Rat
lymph vessel development GO:0001945 27 0.338
biosynthetic process GO:0009058 294 0.337
Human Mouse
establishment of localization GO:0051234 244 0.327
Rat
lymphangiogenesis GO:0001946 25 0.324
lymph vessel morphogenesis GO:0036303 25 0.322
signal transduction GO:0007165 455 0.322
Human Mouse Rat
response to alkaloid GO:0043279 2 0.318
cellular nitrogen compound biosynthetic process GO:0044271 218 0.318
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.316
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.315
Human Mouse
hormone transport GO:0009914 2 0.311
Rat
system process GO:0003008 185 0.311
Rat
steroid hormone mediated signaling pathway GO:0043401 9 0.294
positive regulation of cellular metabolic process GO:0031325 94 0.290
Human
response to drug GO:0042493 3 0.284
organic cyclic compound biosynthetic process GO:1901362 223 0.279
Human Mouse
regulation of gene expression GO:0010468 265 0.278
Human Mouse
sensory organ development GO:0007423 393 0.273
regulation of rna metabolic process GO:0051252 224 0.268
Human Mouse
rna metabolic process GO:0016070 219 0.265
Human Mouse
regulation of metabolic process GO:0019222 359 0.262
Human Mouse
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.254
cellular protein metabolic process GO:0044267 129 0.249
Human Rat
response to carbohydrate GO:0009743 3 0.247
endocrine process GO:0050886 2 0.240
Rat
response to organic cyclic compound GO:0014070 51 0.240
regulation of gonadotropin secretion GO:0032276 1 0.231
Rat
nucleic acid metabolic process GO:0090304 244 0.231
Human Mouse
regulation of endocrine process GO:0044060 2 0.229
Rat
skeletal system morphogenesis GO:0048705 102 0.228
head development GO:0060322 303 0.227
regulation of biosynthetic process GO:0009889 250 0.223
Human Mouse
ovulation cycle GO:0042698 2 0.221
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.221
vasculature development GO:0001944 278 0.217
extrinsic apoptotic signaling pathway GO:0097191 3 0.216
activin receptor signaling pathway GO:0032924 8 0.215
Human Rat
positive regulation of signaling GO:0023056 56 0.213
Human Rat
gene expression GO:0010467 252 0.209
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.207
Human Mouse Rat
cell proliferation GO:0008283 80 0.207
Mouse
gonadotropin secretion GO:0032274 1 0.205
Rat
nucleobase containing compound metabolic process GO:0006139 274 0.201
Human Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.199
locomotion GO:0040011 313 0.199
detection of stimulus involved in sensory perception GO:0050906 21 0.199
single organism transport GO:0044765 206 0.195
Rat
positive regulation of programmed cell death GO:0043068 29 0.192
cognition GO:0050890 1 0.191
positive regulation of cellular process GO:0048522 201 0.190
Human Rat
transcription dna templated GO:0006351 181 0.190
Human Mouse
response to organic substance GO:0010033 153 0.190
Human Rat
phosphorus metabolic process GO:0006793 109 0.189
Human Rat
positive regulation of transport GO:0051050 2 0.189
Rat
detection of stimulus GO:0051606 29 0.184
negative regulation of cellular process GO:0048523 283 0.184
negative regulation of map kinase activity GO:0043407 2 0.183
positive regulation of metabolic process GO:0009893 108 0.183
Human
response to hexose GO:0009746 3 0.182
digestive system development GO:0055123 289 0.181
Mouse
positive regulation of signal transduction GO:0009967 56 0.179
Human
regulation of signaling GO:0023051 235 0.173
Human Mouse Rat
mesoderm development GO:0007498 88 0.171
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.170
Human Mouse
ameboidal type cell migration GO:0001667 143 0.170
regulation of bone mineralization GO:0030500 2 0.167
Human
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.167
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.166
enzyme linked receptor protein signaling pathway GO:0007167 106 0.163
Human Mouse Rat
response to monosaccharide GO:0034284 3 0.160
detection of chemical stimulus involved in sensory perception GO:0050907 3 0.156
organonitrogen compound metabolic process GO:1901564 74 0.155
rhythmic process GO:0048511 21 0.155
sensory perception of chemical stimulus GO:0007606 3 0.154
signal transduction in absence of ligand GO:0038034 1 0.153
rna biosynthetic process GO:0032774 181 0.153
Human Mouse
regulation of programmed cell death GO:0043067 101 0.151
immune system development GO:0002520 191 0.150
Human
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.147
Human
transcription from rna polymerase ii promoter GO:0006366 80 0.145
Human Mouse
brain development GO:0007420 293 0.141
macromolecule modification GO:0043412 111 0.139
Human Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.138
Human Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.133
Human
regulation of signal transduction GO:0009966 225 0.132
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.131
Human Mouse
digestive tract morphogenesis GO:0048546 231 0.130
Mouse
response to glucose GO:0009749 3 0.129
regulation of phosphorus metabolic process GO:0051174 43 0.128
Human
negative regulation of protein kinase activity GO:0006469 4 0.128
positive regulation of macromolecule metabolic process GO:0010604 93 0.126
Human
endodermal cell differentiation GO:0035987 19 0.126
mesenchyme development GO:0060485 127 0.125
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.124
gland development GO:0048732 143 0.124
cell cell signaling GO:0007267 52 0.122
Rat
protein modification process GO:0036211 100 0.120
Human Rat
regulation of transport GO:0051049 45 0.120
Rat
determination of bilateral symmetry GO:0009855 204 0.119
Mouse
positive regulation of protein metabolic process GO:0051247 23 0.117
Human
heterocycle biosynthetic process GO:0018130 215 0.115
Human Mouse
establishment of localization in cell GO:0051649 77 0.114
Rat
development of primary female sexual characteristics GO:0046545 4 0.114
gastrulation GO:0007369 208 0.114
Mouse
carboxylic acid catabolic process GO:0046395 3 0.113
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.112
Human Mouse
female gonad development GO:0008585 4 0.112
organic acid metabolic process GO:0006082 31 0.112
regulation of reproductive process GO:2000241 4 0.110
cellular amide metabolic process GO:0043603 4 0.109
embryonic organ development GO:0048568 381 0.109
positive regulation of cytokine production GO:0001819 2 0.108
embryonic cranial skeleton morphogenesis GO:0048701 90 0.108
positive regulation of defense response to virus by host GO:0002230 0 0.107
regulation of macromolecule biosynthetic process GO:0010556 225 0.106
Human Mouse
ovulation cycle process GO:0022602 2 0.106
single organism biosynthetic process GO:0044711 71 0.105
skeletal system development GO:0001501 181 0.104
mrna catabolic process GO:0006402 6 0.102
detection of chemical stimulus GO:0009593 4 0.101
positive regulation of cellular protein metabolic process GO:0032270 22 0.101
Human
cellular response to lipid GO:0071396 39 0.101
response to metal ion GO:0010038 34 0.101
cellular ketone metabolic process GO:0042180 11 0.101
cellular component movement GO:0006928 335 0.100
neurological system process GO:0050877 62 0.100
cation homeostasis GO:0055080 33 0.098
regulation of hormone levels GO:0010817 21 0.097
Rat
positive regulation of secretion GO:0051047 1 0.096
Rat
regulation of transcription dna templated GO:0006355 213 0.095
Human Mouse
endoderm development GO:0007492 49 0.094
single organism metabolic process GO:0044710 217 0.093
Mouse
stem cell proliferation GO:0072089 4 0.091
positive regulation of immune system process GO:0002684 17 0.091
Human
cellular response to hormone stimulus GO:0032870 39 0.091
neurotransmitter transport GO:0006836 2 0.090
gtp metabolic process GO:0046039 4 0.090
sensory perception GO:0007600 39 0.089
small molecule metabolic process GO:0044281 77 0.089
retina vasculature development in camera type eye GO:0061298 2 0.089
rna catabolic process GO:0006401 7 0.089
regulation of cell death GO:0010941 103 0.088
retina development in camera type eye GO:0060041 146 0.088
regulation of system process GO:0044057 40 0.086
Rat
response to stress GO:0006950 263 0.085
regulation of response to stimulus GO:0048583 269 0.084
Human Mouse
organic acid catabolic process GO:0016054 3 0.082
eye development GO:0001654 277 0.082
regulation of immune system process GO:0002682 34 0.082
Human
regulation of purine nucleotide catabolic process GO:0033121 2 0.081
negative regulation of nuclear division GO:0051784 3 0.081
positive regulation of cell communication GO:0010647 56 0.081
Human Rat
cartilage development GO:0051216 96 0.081
erk1 and erk2 cascade GO:0070371 4 0.080
bmp signaling pathway GO:0030509 52 0.080
Human Mouse
intracellular signal transduction GO:0035556 85 0.078
pronuclear migration GO:0035046 1 0.077
cellular macromolecule biosynthetic process GO:0034645 224 0.077
Human Mouse
camera type eye development GO:0043010 222 0.076
response to lipid GO:0033993 60 0.075
regulation of phosphate metabolic process GO:0019220 43 0.075
Human
regulation of apoptotic process GO:0042981 98 0.073
positive regulation of response to stimulus GO:0048584 80 0.073
Human
response to alcohol GO:0097305 14 0.073
connective tissue development GO:0061448 99 0.073
negative regulation of cell cycle GO:0045786 14 0.073
neural crest cell development GO:0014032 62 0.072
cellular localization GO:0051641 97 0.072
Rat
homeostatic process GO:0042592 142 0.071
Human
cellular response to molecule of bacterial origin GO:0071219 3 0.070
regulation of defense response to virus by host GO:0050691 1 0.069
cellular response to chemical stimulus GO:0070887 157 0.069
Human
single organism localization GO:1902578 225 0.069
Rat
positive regulation of cellular biosynthetic process GO:0031328 68 0.068
blood vessel development GO:0001568 246 0.068
tube morphogenesis GO:0035239 349 0.067
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.067
biomineral tissue development GO:0031214 13 0.066
Human
protein localization to nucleus GO:0034504 3 0.065
regulation of oocyte development GO:0060281 3 0.065
positive regulation of developmental process GO:0051094 50 0.064
Human
peptide metabolic process GO:0006518 1 0.063
cellular protein modification process GO:0006464 100 0.063
Human Rat
regulation of phosphorylation GO:0042325 26 0.063
Human
negative regulation of mitosis GO:0045839 3 0.062
protein metabolic process GO:0019538 183 0.062
Human Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.062
Human Mouse Rat
oxidation reduction process GO:0055114 41 0.061
Mouse
transport GO:0006810 220 0.061
Rat
neurotransmitter secretion GO:0007269 2 0.060
calcium ion transport into cytosol GO:0060402 3 0.059
regulation of carbohydrate metabolic process GO:0006109 4 0.059
hormone biosynthetic process GO:0042446 3 0.058
negative regulation of mapk cascade GO:0043409 4 0.058
ovarian follicle development GO:0001541 2 0.058
cellular response to external stimulus GO:0071496 2 0.057
response to bacterium GO:0009617 58 0.056
response to endogenous stimulus GO:0009719 83 0.056
Human
cell motility GO:0048870 244 0.056
negative regulation of oocyte development GO:0060283 2 0.056
response to hormone GO:0009725 48 0.055
nuclear migration GO:0007097 3 0.055
cellular response to antibiotic GO:0071236 1 0.054
regulation of intracellular signal transduction GO:1902531 57 0.054
regulation of rna biosynthetic process GO:2001141 213 0.054
Human Mouse
heart morphogenesis GO:0003007 156 0.053
regulation of protein metabolic process GO:0051246 56 0.053
Human
oxoacid metabolic process GO:0043436 31 0.053
phosphorylation GO:0016310 69 0.053
Human Rat
determination of left right symmetry GO:0007368 179 0.053
Mouse
metal ion homeostasis GO:0055065 26 0.052
protein phosphorylation GO:0006468 47 0.052
Human Rat
protein localization to plasma membrane GO:0072659 1 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.052
chemical homeostasis GO:0048878 49 0.052
organophosphate biosynthetic process GO:0090407 23 0.051
small molecule catabolic process GO:0044282 3 0.051
regulation of protein transport GO:0051223 3 0.050
female sex differentiation GO:0046660 4 0.050
nucleic acid templated transcription GO:0097659 181 0.050
Human Mouse
regulation of erk1 and erk2 cascade GO:0070372 4 0.049
cellular amino acid metabolic process GO:0006520 7 0.049
organelle fusion GO:0048284 3 0.049
regulation of multicellular organismal process GO:0051239 277 0.049
Human Rat
guanosine containing compound catabolic process GO:1901069 2 0.048
blood vessel morphogenesis GO:0048514 216 0.048
regulation of nucleoside metabolic process GO:0009118 2 0.048
negative regulation of signal transduction GO:0009968 94 0.047
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.047
Human Mouse
guanosine containing compound metabolic process GO:1901068 4 0.047
generation of neurons GO:0048699 385 0.047
positive regulation of apoptotic process GO:0043065 29 0.047
regulation of cell proliferation GO:0042127 37 0.047
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
respiratory system development GO:0060541 5 0.046
positive regulation of cellular component biogenesis GO:0044089 3 0.046
response to steroid hormone GO:0048545 35 0.046
dicarboxylic acid metabolic process GO:0043648 1 0.046
response to glucocorticoid GO:0051384 1 0.046
cellular amine metabolic process GO:0044106 2 0.045
maintenance of location GO:0051235 4 0.045
positive regulation of multi organism process GO:0043902 3 0.045
regulation of protein phosphorylation GO:0001932 18 0.044
Human
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.044
determination of ventral identity GO:0048264 21 0.044
odontogenesis GO:0042476 9 0.044
programmed cell death GO:0012501 119 0.043
regulation of cytoplasmic transport GO:1903649 4 0.043
tissue remodeling GO:0048771 4 0.043
response to oxygen containing compound GO:1901700 55 0.043
cell death GO:0008219 121 0.043
regulation of cellular ketone metabolic process GO:0010565 7 0.043
endoderm formation GO:0001706 29 0.043
cell projection organization GO:0030030 284 0.042
death GO:0016265 121 0.042
amine metabolic process GO:0009308 2 0.042
response to corticosteroid GO:0031960 1 0.042
neural crest cell migration GO:0001755 42 0.041
wound healing GO:0042060 90 0.041
specification of symmetry GO:0009799 204 0.040
Mouse
regulation of catalytic activity GO:0050790 55 0.040
Mouse
apoptotic process GO:0006915 116 0.040
cellular response to organic substance GO:0071310 105 0.040
Human
heart development GO:0007507 313 0.039
regulation of hydrolase activity GO:0051336 28 0.039
amide transport GO:0042886 12 0.039
androgen metabolic process GO:0008209 2 0.039
negative regulation of reproductive process GO:2000242 3 0.039
translational initiation GO:0006413 3 0.039
lipid metabolic process GO:0006629 52 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.038
Human
regulation of cytokine production GO:0001817 3 0.038
endochondral bone growth GO:0003416 2 0.038
purine containing compound metabolic process GO:0072521 29 0.037
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.037
regulation of tube size GO:0035150 2 0.037
inositol lipid mediated signaling GO:0048017 2 0.037
nitrogen compound transport GO:0071705 23 0.037
neuron differentiation GO:0030182 353 0.037
regulation of multicellular organismal development GO:2000026 223 0.037
Human
positive regulation of cellular amine metabolic process GO:0033240 0 0.036
positive regulation of cell differentiation GO:0045597 30 0.036
Human
stem cell maintenance GO:0019827 4 0.036
cellular response to biotic stimulus GO:0071216 3 0.035
phosphate containing compound metabolic process GO:0006796 108 0.035
Human Rat
muscle cell differentiation GO:0042692 139 0.035
regulation of mapk cascade GO:0043408 14 0.035
response to antibiotic GO:0046677 1 0.035
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.035
i kappab kinase nf kappab signaling GO:0007249 4 0.035
regulation of dendrite development GO:0050773 3 0.034
digestive tract development GO:0048565 265 0.034
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.034
regulation of stem cell proliferation GO:0072091 2 0.034
cell growth GO:0016049 57 0.034
macromolecular complex subunit organization GO:0043933 74 0.033
oocyte maturation GO:0001556 4 0.033
regulation of metal ion transport GO:0010959 4 0.033
antimicrobial humoral response GO:0019730 2 0.033
nucleobase containing compound biosynthetic process GO:0034654 205 0.033
Human Mouse
neural nucleus development GO:0048857 15 0.033
positive regulation of synapse assembly GO:0051965 1 0.033
negative regulation of programmed cell death GO:0043069 58 0.033
response to abiotic stimulus GO:0009628 122 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
regulation of cysteine type endopeptidase activity GO:2000116 21 0.033
apoptotic signaling pathway GO:0097190 23 0.033
negative regulation of signaling GO:0023057 96 0.033
negative regulation of kinase activity GO:0033673 4 0.032
cellular nitrogen compound catabolic process GO:0044270 15 0.032
regulation of nucleotide metabolic process GO:0006140 17 0.032
mesenchymal cell proliferation GO:0010463 1 0.032
synaptic transmission GO:0007268 35 0.032
regulation of fatty acid metabolic process GO:0019217 1 0.032
macromolecule localization GO:0033036 54 0.032
cell cycle arrest GO:0007050 1 0.032
morphogenesis of an epithelial fold GO:0060571 1 0.032
regulation of blood vessel size GO:0050880 2 0.031
establishment of protein localization to plasma membrane GO:0090002 1 0.031
positive regulation of neural precursor cell proliferation GO:2000179 1 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
formation of primary germ layer GO:0001704 62 0.030
ribonucleotide metabolic process GO:0009259 27 0.030
regulation of nervous system development GO:0051960 90 0.030
response to cold GO:0009409 4 0.029
metal ion transport GO:0030001 58 0.029
nucleoside phosphate metabolic process GO:0006753 28 0.029
regulation of blood pressure GO:0008217 1 0.029
cell cycle process GO:0022402 53 0.029
sprouting angiogenesis GO:0002040 53 0.028
neuron neuron synaptic transmission GO:0007270 1 0.028
renal system development GO:0072001 94 0.028
protein localization GO:0008104 40 0.028
purine ribonucleotide metabolic process GO:0009150 27 0.028
catabolic process GO:0009056 32 0.028
positive regulation of immune response GO:0050778 11 0.028
positive regulation of camp biosynthetic process GO:0030819 2 0.028
monovalent inorganic cation homeostasis GO:0055067 9 0.028
striated muscle cell differentiation GO:0051146 129 0.028
cytosolic calcium ion transport GO:0060401 3 0.028
autophagy GO:0006914 4 0.027
regulation of synaptic plasticity GO:0048167 1 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.027
glucose homeostasis GO:0042593 1 0.027
cation transport GO:0006812 81 0.027
organophosphate metabolic process GO:0019637 37 0.027
regionalization GO:0003002 274 0.027
Mouse
positive regulation of catalytic activity GO:0043085 25 0.027
gtp catabolic process GO:0006184 2 0.027
regulation of neurotransmitter secretion GO:0046928 1 0.026
erythrocyte homeostasis GO:0034101 55 0.026
Human
protein polymerization GO:0051258 4 0.026
positive regulation of phosphorus metabolic process GO:0010562 21 0.026
Human
positive regulation of gene expression GO:0010628 71 0.026
positive regulation of bmp signaling pathway GO:0030513 10 0.026
regulation of camp biosynthetic process GO:0030817 9 0.025
regulation of gtpase activity GO:0043087 2 0.025
regulation of cellular component organization GO:0051128 86 0.025
regulation of bmp signaling pathway GO:0030510 39 0.025
Mouse
cellular response to organic cyclic compound GO:0071407 38 0.025
growth plate cartilage development GO:0003417 2 0.025
regulation of mitochondrion organization GO:0010821 1 0.025
positive regulation of molecular function GO:0044093 33 0.025
forebrain development GO:0030900 96 0.025
developmental growth GO:0048589 166 0.025
negative regulation of phosphorus metabolic process GO:0010563 13 0.025
response to lipopolysaccharide GO:0032496 13 0.025
single fertilization GO:0007338 3 0.025
camp metabolic process GO:0046058 11 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
Mouse
negative regulation of cell death GO:0060548 60 0.024
fertilization GO:0009566 3 0.024
positive regulation of multicellular organismal process GO:0051240 52 0.024
Human Rat
rna localization GO:0006403 4 0.024
gastrulation with mouth forming second GO:0001702 44 0.024
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.024
skeletal muscle fiber development GO:0048741 35 0.024
cell migration GO:0016477 237 0.023
cellular response to endogenous stimulus GO:0071495 68 0.023
Human
ion homeostasis GO:0050801 41 0.023
cell cycle GO:0007049 93 0.023
immune system process GO:0002376 241 0.023
Human
cofactor metabolic process GO:0051186 15 0.023
cytokinesis GO:0000910 3 0.023
neuromuscular synaptic transmission GO:0007274 2 0.023
regulation of sequestering of calcium ion GO:0051282 4 0.023
cortical actin cytoskeleton organization GO:0030866 1 0.023
embryonic skeletal system development GO:0048706 97 0.023
Mouse
digestive tract mesoderm development GO:0007502 1 0.023
embryonic limb morphogenesis GO:0030326 2 0.023
purine nucleotide biosynthetic process GO:0006164 20 0.023
transmission of nerve impulse GO:0019226 19 0.023
aromatic compound catabolic process GO:0019439 15 0.022
multicellular organismal signaling GO:0035637 22 0.022
regulation of systemic arterial blood pressure GO:0003073 1 0.022
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.022
peptidyl threonine phosphorylation GO:0018107 1 0.022
regulation of mesenchymal cell proliferation GO:0010464 1 0.022
positive regulation of cell activation GO:0050867 1 0.022
fin regeneration GO:0031101 51 0.022
glucocorticoid metabolic process GO:0008211 2 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
chordate embryonic development GO:0043009 271 0.022
Mouse
response to other organism GO:0051707 97 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.022
multicellular organism growth GO:0035264 4 0.021
regulation of cell differentiation GO:0045595 142 0.021
Human
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.021
negative regulation of gene expression GO:0010629 65 0.021
hepaticobiliary system development GO:0061008 98 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
transmembrane transport GO:0055085 120 0.021
kidney development GO:0001822 92 0.021
regulation of production of molecular mediator of immune response GO:0002700 1 0.021
nuclear transcribed mrna catabolic process GO:0000956 4 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.020
double strand break repair via nonhomologous end joining GO:0006303 1 0.020
determination of dorsal ventral asymmetry GO:0048262 34 0.020
regulation of neurotransmitter transport GO:0051588 1 0.020
regulation of purine nucleotide metabolic process GO:1900542 17 0.020
growth GO:0040007 174 0.020
cellular lipid metabolic process GO:0044255 36 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
neuroblast proliferation GO:0007405 2 0.020
liver development GO:0001889 96 0.020
regulation of transmembrane transporter activity GO:0022898 2 0.020
midbrain development GO:0030901 28 0.020
axon development GO:0061564 166 0.020
membrane fusion GO:0061025 2 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
sequestering of metal ion GO:0051238 3 0.020
reproductive process GO:0022414 40 0.020
Mouse
regulation of ion transmembrane transporter activity GO:0032412 2 0.020
multicellular organismal reproductive process GO:0048609 35 0.020
Mouse
regulation of developmental process GO:0050793 247 0.020
Human
osteoblast differentiation GO:0001649 5 0.019
Human
negative regulation of metabolic process GO:0009892 86 0.019
organonitrogen compound biosynthetic process GO:1901566 47 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
response to vitamin GO:0033273 3 0.019
protein secretion GO:0009306 1 0.019
positive regulation of rna metabolic process GO:0051254 59 0.019
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.019
regulation of protein catabolic process GO:0042176 1 0.019
neural retina development GO:0003407 49 0.019
specification of axis polarity GO:0065001 4 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
mitochondrion organization GO:0007005 4 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
response to nicotine GO:0035094 2 0.018
sensory organ morphogenesis GO:0090596 200 0.018
embryonic viscerocranium morphogenesis GO:0048703 52 0.018
cellular response to oxygen levels GO:0071453 1 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
regulation of immune response GO:0050776 14 0.018
lipid catabolic process GO:0016042 4 0.018

acvr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.104
disease of anatomical entity DOID:7 0 0.027
disease of metabolism DOID:0014667 0 0.022
cardiovascular system disease DOID:1287 0 0.020
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018