Danio rerio

0 known processes

adka

adenosine kinase a

(Aliases: wu:fi37c12,cb163,wu:fb57c05,wu:fb39g06,wu:fc10c08,wu:fc41g07,MGC191204,adk)

adka biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular biosynthetic process GO:0044249 286 0.495
regulation of nitrogen compound metabolic process GO:0051171 251 0.405
aromatic compound biosynthetic process GO:0019438 217 0.394
cellular aromatic compound metabolic process GO:0006725 295 0.385
larval development GO:0002164 2 0.376
Worm
macromolecule biosynthetic process GO:0009059 227 0.322
regulation of primary metabolic process GO:0080090 311 0.315
organic cyclic compound biosynthetic process GO:1901362 223 0.301
lipid storage GO:0019915 1 0.295
regulation of mrna splicing via spliceosome GO:0048024 3 0.244
determination of bilateral symmetry GO:0009855 204 0.238
biosynthetic process GO:0009058 294 0.233
regulation of metabolic process GO:0019222 359 0.230
nucleobase containing compound metabolic process GO:0006139 274 0.213
regulation of macromolecule metabolic process GO:0060255 317 0.212
negative regulation of cellular process GO:0048523 283 0.200
locomotion GO:0040011 313 0.196
rna biosynthetic process GO:0032774 181 0.193
cellular nitrogen compound biosynthetic process GO:0044271 218 0.178
cellular nitrogen compound metabolic process GO:0034641 290 0.171
organic substance biosynthetic process GO:1901576 289 0.167
response to antibiotic GO:0046677 1 0.161
regulation of rna biosynthetic process GO:2001141 213 0.150
regulation of cellular metabolic process GO:0031323 320 0.142
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.130
maintenance of location GO:0051235 4 0.129
regulation of mrna processing GO:0050684 3 0.127
heterocycle metabolic process GO:0046483 290 0.113
rna metabolic process GO:0016070 219 0.110
death GO:0016265 121 0.108
heterocycle biosynthetic process GO:0018130 215 0.100
regulation of cell death GO:0010941 103 0.095
response to organic substance GO:0010033 153 0.092
cellular macromolecule biosynthetic process GO:0034645 224 0.091
apoptotic process GO:0006915 116 0.091
alternative mrna splicing via spliceosome GO:0000380 1 0.090
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.088
cellular response to organic substance GO:0071310 105 0.088
negative regulation of response to stimulus GO:0048585 104 0.087
protein metabolic process GO:0019538 183 0.084
single organism metabolic process GO:0044710 217 0.083
cellular response to hypoxia GO:0071456 1 0.082
regulation of nucleic acid templated transcription GO:1903506 213 0.081
cellular amine metabolic process GO:0044106 2 0.081
cell proliferation GO:0008283 80 0.081
oxoacid metabolic process GO:0043436 31 0.079
regulation of developmental process GO:0050793 247 0.076
transcription dna templated GO:0006351 181 0.075
positive regulation of cellular process GO:0048522 201 0.074
positive regulation of transport GO:0051050 2 0.074
amine metabolic process GO:0009308 2 0.074
cellular protein metabolic process GO:0044267 129 0.073
skeletal muscle tissue development GO:0007519 67 0.073
neuron development GO:0048666 262 0.073
regulation of macromolecule biosynthetic process GO:0010556 225 0.072
regulation of signal transduction GO:0009966 225 0.069
regulation of biosynthetic process GO:0009889 250 0.069
negative regulation of cellular catabolic process GO:0031330 3 0.067
response to chemical GO:0042221 320 0.067
cellular amino acid biosynthetic process GO:0008652 2 0.063
sensory organ development GO:0007423 393 0.063
cell death GO:0008219 121 0.063
regulation of cellular biosynthetic process GO:0031326 245 0.063
organonitrogen compound metabolic process GO:1901564 74 0.062
negative regulation of biological process GO:0048519 304 0.062
positive regulation of wound healing GO:0090303 1 0.061
cellular response to chemical stimulus GO:0070887 157 0.060
dicarboxylic acid metabolic process GO:0043648 1 0.059
regulation of transcription dna templated GO:0006355 213 0.059
organic cyclic compound metabolic process GO:1901360 301 0.058
cellular macromolecule metabolic process GO:0044260 391 0.058
positive regulation of biological process GO:0048518 253 0.056
nucleic acid metabolic process GO:0090304 244 0.056
nucleic acid templated transcription GO:0097659 181 0.055
determination of heart left right asymmetry GO:0061371 117 0.055
cell surface receptor signaling pathway GO:0007166 325 0.054
small molecule metabolic process GO:0044281 77 0.054
nitrogen compound metabolic process GO:0006807 319 0.054
determination of left right symmetry GO:0007368 179 0.053
regulation of gene expression GO:0010468 265 0.053
positive regulation of cell cycle GO:0045787 3 0.052
organic acid metabolic process GO:0006082 31 0.051
response to external stimulus GO:0009605 264 0.051
alpha amino acid metabolic process GO:1901605 3 0.050
carboxylic acid metabolic process GO:0019752 22 0.050
leukocyte proliferation GO:0070661 1 0.049
response to organic cyclic compound GO:0014070 51 0.049
meiotic cell cycle process GO:1903046 3 0.049
negative regulation of signal transduction GO:0009968 94 0.047
response to drug GO:0042493 3 0.047
response to vitamin b3 GO:0033552 2 0.047
cell part morphogenesis GO:0032990 246 0.046
stem cell maintenance GO:0019827 4 0.046
b cell activation GO:0042113 2 0.045
signal transduction GO:0007165 455 0.045
tube morphogenesis GO:0035239 349 0.044
regulation of cell activation GO:0050865 1 0.044
establishment of localization in cell GO:0051649 77 0.044
Worm
specification of symmetry GO:0009799 204 0.044
vasculature development GO:0001944 278 0.042
negative regulation of metabolic process GO:0009892 86 0.041
regulation of cellular ketone metabolic process GO:0010565 7 0.041
embryonic organ development GO:0048568 381 0.040
cell motility GO:0048870 244 0.040
wound healing GO:0042060 90 0.040
regulation of biological quality GO:0065008 263 0.040
cellular ketone metabolic process GO:0042180 11 0.039
muscle structure development GO:0061061 196 0.039
organelle organization GO:0006996 227 0.039
intra s dna damage checkpoint GO:0031573 1 0.038
regulation of response to stimulus GO:0048583 269 0.038
circulatory system process GO:0003013 87 0.037
cellular amino acid metabolic process GO:0006520 7 0.037
cellular response to external stimulus GO:0071496 2 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
aging GO:0007568 2 0.035
programmed cell death GO:0012501 119 0.035
negative regulation of rna metabolic process GO:0051253 48 0.035
response to metal ion GO:0010038 34 0.035
protein targeting to membrane GO:0006612 1 0.033
cellular response to oxygen levels GO:0071453 1 0.033
single organism organelle organization GO:1902589 199 0.033
response to hormone GO:0009725 48 0.032
heart development GO:0007507 313 0.032
negative regulation of rna splicing GO:0033119 1 0.031
response to oxygen levels GO:0070482 25 0.031
positive regulation of metabolic process GO:0009893 108 0.031
negative regulation of signaling GO:0023057 96 0.031
cellular response to lipid GO:0071396 39 0.031
regulation of apoptotic process GO:0042981 98 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.030
regulation of fatty acid metabolic process GO:0019217 1 0.029
cellular component movement GO:0006928 335 0.029
nucleotide metabolic process GO:0009117 28 0.029
mononuclear cell proliferation GO:0032943 1 0.029
meiotic nuclear division GO:0007126 4 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
response to biotic stimulus GO:0009607 97 0.029
positive regulation of translation GO:0045727 1 0.029
response to nutrient GO:0007584 3 0.028
response to hexose GO:0009746 3 0.028
b cell differentiation GO:0030183 1 0.028
negative regulation of cellular biosynthetic process GO:0031327 55 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
adult behavior GO:0030534 2 0.028
regulation of cell substrate adhesion GO:0010810 1 0.028
type i interferon production GO:0032606 2 0.028
negative regulation of protein kinase activity GO:0006469 4 0.027
establishment of localization GO:0051234 244 0.027
Worm
blood vessel development GO:0001568 246 0.027
regulation of signaling GO:0023051 235 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
response to stress GO:0006950 263 0.025
gland development GO:0048732 143 0.025
negative regulation of biosynthetic process GO:0009890 55 0.025
eye morphogenesis GO:0048592 144 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
cellular component morphogenesis GO:0032989 336 0.025
cellular response to decreased oxygen levels GO:0036294 1 0.025
endoplasmic reticulum unfolded protein response GO:0030968 2 0.025
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
heart morphogenesis GO:0003007 156 0.024
cellular response to steroid hormone stimulus GO:0071383 31 0.024
regulation of cell communication GO:0010646 232 0.024
negative regulation of gene expression GO:0010629 65 0.024
negative regulation of leukocyte differentiation GO:1902106 1 0.024
eye development GO:0001654 277 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
response to external biotic stimulus GO:0043207 97 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.023
camera type eye development GO:0043010 222 0.023
purine containing compound metabolic process GO:0072521 29 0.023
cellular component biogenesis GO:0044085 178 0.023
regulation of rna metabolic process GO:0051252 224 0.023
muscle organ development GO:0007517 101 0.022
cellular response to starvation GO:0009267 1 0.022
organonitrogen compound biosynthetic process GO:1901566 47 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
liver development GO:0001889 96 0.022
response to unfolded protein GO:0006986 2 0.022
embryonic heart tube development GO:0035050 133 0.022
lymphocyte proliferation GO:0046651 1 0.022
regulation of cellular component organization GO:0051128 86 0.021
phagocytosis GO:0006909 3 0.021
cofactor metabolic process GO:0051186 15 0.021
response to steroid hormone GO:0048545 35 0.021
negative regulation of cell communication GO:0010648 96 0.021
iron ion transmembrane transport GO:0034755 3 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of phosphate metabolic process GO:0019220 43 0.020
endosomal transport GO:0016197 2 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
establishment of protein localization to organelle GO:0072594 4 0.019
neuron differentiation GO:0030182 353 0.019
oocyte maturation GO:0001556 4 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
protein import GO:0017038 3 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
cell migration GO:0016477 237 0.019
mitochondrion organization GO:0007005 4 0.019
mrna metabolic process GO:0016071 20 0.019
response to uv GO:0009411 3 0.019
gene expression GO:0010467 252 0.019
response to ketone GO:1901654 1 0.019
negative regulation of developmental process GO:0051093 65 0.019
response to corticosteroid GO:0031960 1 0.018
response to hypoxia GO:0001666 25 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
cellular response to organic cyclic compound GO:0071407 38 0.018
regulation of programmed cell death GO:0043067 101 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
mitochondrion morphogenesis GO:0070584 2 0.018
positive regulation of cell activation GO:0050867 1 0.018
homeostatic process GO:0042592 142 0.018
immunoglobulin mediated immune response GO:0016064 3 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
tissue regeneration GO:0042246 74 0.017
meiotic chromosome segregation GO:0045132 3 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
heart looping GO:0001947 94 0.017
extracellular matrix organization GO:0030198 27 0.017
response to endogenous stimulus GO:0009719 83 0.017
negative regulation of mrna processing GO:0050686 1 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
cellular response to nutrient levels GO:0031669 2 0.017
rna export from nucleus GO:0006405 1 0.016
response to carbohydrate GO:0009743 3 0.016
regulation of kinase activity GO:0043549 15 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
response to oxygen containing compound GO:1901700 55 0.016
hepaticobiliary system development GO:0061008 98 0.016
antimicrobial humoral response GO:0019730 2 0.016
autophagy GO:0006914 4 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
establishment of rna localization GO:0051236 3 0.016
long chain fatty acid transport GO:0015909 1 0.016
intracellular estrogen receptor signaling pathway GO:0030520 3 0.016
neural crest cell differentiation GO:0014033 72 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
generation of neurons GO:0048699 385 0.015
multi organism process GO:0051704 134 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
anatomical structure arrangement GO:0048532 2 0.015
regulation of metal ion transport GO:0010959 4 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of protein metabolic process GO:0051246 56 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
regulation of dna replication GO:0006275 3 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
cell morphogenesis GO:0000902 289 0.015
chromosome organization GO:0051276 31 0.015
response to monosaccharide GO:0034284 3 0.015
single organism biosynthetic process GO:0044711 71 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
immune system development GO:0002520 191 0.015
regulation of circadian rhythm GO:0042752 4 0.015
single organism catabolic process GO:0044712 13 0.014
localization of cell GO:0051674 244 0.014
embryonic heart tube morphogenesis GO:0003143 108 0.014
regulation of nuclease activity GO:0032069 1 0.014
pigmentation GO:0043473 85 0.014
digestive tract development GO:0048565 265 0.014
cellular response to xenobiotic stimulus GO:0071466 35 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
lipid homeostasis GO:0055088 3 0.014
transport GO:0006810 220 0.014
Worm
cellular biogenic amine metabolic process GO:0006576 2 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
cell projection organization GO:0030030 284 0.014
regulation of translational initiation GO:0006446 1 0.014
small molecule catabolic process GO:0044282 3 0.014
positive regulation of immune effector process GO:0002699 3 0.014
cellular localization GO:0051641 97 0.014
Worm
negative regulation of reproductive process GO:2000242 3 0.014
immune system process GO:0002376 241 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
monovalent inorganic cation transport GO:0015672 42 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
fatty acid transport GO:0015908 1 0.013
cellular lipid metabolic process GO:0044255 36 0.013
blood vessel morphogenesis GO:0048514 216 0.013
fin development GO:0033333 77 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.013
phosphorus metabolic process GO:0006793 109 0.013
cellular protein localization GO:0034613 20 0.013
growth GO:0040007 174 0.013
stem cell differentiation GO:0048863 117 0.013
rna localization GO:0006403 4 0.013
carboxylic acid biosynthetic process GO:0046394 12 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
response to vitamin GO:0033273 3 0.013
angiogenesis GO:0001525 158 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
camera type eye morphogenesis GO:0048593 108 0.013
extracellular structure organization GO:0043062 27 0.013
b cell mediated immunity GO:0019724 3 0.013
iron ion transport GO:0006826 4 0.013
response to glucose GO:0009749 3 0.013
positive regulation of cell death GO:0010942 29 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
cell cycle arrest GO:0007050 1 0.012
regulation of wound healing GO:0061041 2 0.012
cellular response to stress GO:0033554 62 0.012
head development GO:0060322 303 0.012
negative regulation of cell death GO:0060548 60 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
single organism transport GO:0044765 206 0.012
Worm
regulation of gtpase activity GO:0043087 2 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
peptide transport GO:0015833 1 0.012
membrane repolarization GO:0086009 2 0.012
nuclear transport GO:0051169 4 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
immunoglobulin production GO:0002377 1 0.012
regulation of cell proliferation GO:0042127 37 0.012
response to topologically incorrect protein GO:0035966 2 0.012
hormone secretion GO:0046879 2 0.012
chromosome segregation GO:0007059 12 0.012
response to virus GO:0009615 21 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
cell aging GO:0007569 2 0.011
skeletal muscle organ development GO:0060538 78 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
system process GO:0003008 185 0.011
spindle assembly GO:0051225 2 0.011
cytokinesis GO:0000910 3 0.011
single organism nuclear import GO:1902593 3 0.011
positive regulation of striated muscle cell differentiation GO:0051155 1 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
regulation of blood pressure GO:0008217 1 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
heart process GO:0003015 71 0.011
negative regulation of nuclear division GO:0051784 3 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
gtp catabolic process GO:0006184 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
female meiotic division GO:0007143 2 0.011
regulation of protein transport GO:0051223 3 0.011
peptidyl lysine methylation GO:0018022 3 0.011
response to other organism GO:0051707 97 0.011
nuclear import GO:0051170 3 0.010
brain development GO:0007420 293 0.010
lipid metabolic process GO:0006629 52 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
multi organism cellular process GO:0044764 2 0.010
dna catabolic process GO:0006308 1 0.010
neuron projection development GO:0031175 180 0.010
regulation of blood vessel size GO:0050880 2 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
regulation of cell differentiation GO:0045595 142 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
behavior GO:0007610 74 0.010
response to inorganic substance GO:0010035 38 0.010
protein localization to nucleus GO:0034504 3 0.010
regionalization GO:0003002 274 0.010
small molecule biosynthetic process GO:0044283 16 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
peptide metabolic process GO:0006518 1 0.010
cell substrate adhesion GO:0031589 4 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
cell cycle process GO:0022402 53 0.010
regulation of cytokine production GO:0001817 3 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
positive regulation of secretion GO:0051047 1 0.010

adka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.185
inherited metabolic disorder DOID:655 0 0.076
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
bone disease DOID:0080001 0 0.016
bone development disease DOID:0080006 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
disease of mental health DOID:150 0 0.012
developmental disorder of mental health DOID:0060037 0 0.012