Danio rerio

0 known processes

akap8l

A kinase (PRKA) anchor protein 8-like

(Aliases: zgc:85966)

akap8l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 181 0.255
cellular macromolecule metabolic process GO:0044260 391 0.197
cellular macromolecule biosynthetic process GO:0034645 224 0.156
organelle organization GO:0006996 227 0.153
biosynthetic process GO:0009058 294 0.133
cellular nitrogen compound biosynthetic process GO:0044271 218 0.132
organic cyclic compound biosynthetic process GO:1901362 223 0.123
regulation of nucleic acid templated transcription GO:1903506 213 0.117
regulation of nitrogen compound metabolic process GO:0051171 251 0.112
embryo development ending in birth or egg hatching GO:0009792 271 0.111
aging GO:0007568 2 0.111
negative regulation of ras protein signal transduction GO:0046580 1 0.110
macromolecule biosynthetic process GO:0009059 227 0.109
response to chemical GO:0042221 320 0.108
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.099
negative regulation of cellular process GO:0048523 283 0.099
heterocycle metabolic process GO:0046483 290 0.097
nitrogen compound metabolic process GO:0006807 319 0.093
nucleic acid templated transcription GO:0097659 181 0.091
cellular biosynthetic process GO:0044249 286 0.088
rna biosynthetic process GO:0032774 181 0.088
cellular aromatic compound metabolic process GO:0006725 295 0.085
nuclear export GO:0051168 1 0.084
maintenance of location GO:0051235 4 0.084
signal transduction GO:0007165 455 0.082
cellular nitrogen compound metabolic process GO:0034641 290 0.081
regulation of protein transport GO:0051223 3 0.081
ubiquitin dependent protein catabolic process GO:0006511 3 0.081
regulation of transcription dna templated GO:0006355 213 0.080
intracellular signal transduction GO:0035556 85 0.079
regulation of establishment of protein localization GO:0070201 4 0.074
regulation of metabolic process GO:0019222 359 0.073
single organism nuclear import GO:1902593 3 0.072
negative regulation of metabolic process GO:0009892 86 0.071
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.071
negative regulation of cellular metabolic process GO:0031324 77 0.071
positive regulation of transport GO:0051050 2 0.069
regulation of cytoplasmic transport GO:1903649 4 0.067
cytokinesis GO:0000910 3 0.066
single organism organelle organization GO:1902589 199 0.066
regulation of biological quality GO:0065008 263 0.065
heterocycle biosynthetic process GO:0018130 215 0.065
homeostatic process GO:0042592 142 0.064
regulation of mrna splicing via spliceosome GO:0048024 3 0.064
cellular ketone metabolic process GO:0042180 11 0.063
positive regulation of cellular amine metabolic process GO:0033240 0 0.063
regulation of rna metabolic process GO:0051252 224 0.062
cellular component biogenesis GO:0044085 178 0.062
aromatic compound biosynthetic process GO:0019438 217 0.062
protein localization to nucleus GO:0034504 3 0.061
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.061
establishment of protein localization to organelle GO:0072594 4 0.060
regulation of cellular ketone metabolic process GO:0010565 7 0.060
cellular protein metabolic process GO:0044267 129 0.060
regulation of cellular amine metabolic process GO:0033238 0 0.057
nucleobase containing compound biosynthetic process GO:0034654 205 0.057
regulation of gene expression GO:0010468 265 0.057
regulation of erk1 and erk2 cascade GO:0070372 4 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.056
nuclear import GO:0051170 3 0.056
rna metabolic process GO:0016070 219 0.056
meiotic nuclear division GO:0007126 4 0.056
protein metabolic process GO:0019538 183 0.055
nucleocytoplasmic transport GO:0006913 4 0.054
protein import GO:0017038 3 0.053
amine metabolic process GO:0009308 2 0.053
regulation of mrna processing GO:0050684 3 0.053
alternative mrna splicing via spliceosome GO:0000380 1 0.053
spermatid differentiation GO:0048515 2 0.052
regulation of cellular biosynthetic process GO:0031326 245 0.050
larval development GO:0002164 2 0.050
macromolecular complex subunit organization GO:0043933 74 0.048
modification dependent protein catabolic process GO:0019941 3 0.048
rna splicing GO:0008380 16 0.048
oocyte anterior posterior axis specification GO:0007314 4 0.048
organic cyclic compound metabolic process GO:1901360 301 0.047
protein targeting to nucleus GO:0044744 3 0.047
protein import into nucleus GO:0006606 3 0.046
organic acid metabolic process GO:0006082 31 0.046
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
cellular component assembly GO:0022607 170 0.045
gene expression GO:0010467 252 0.045
embryonic organ morphogenesis GO:0048562 274 0.045
regulation of biosynthetic process GO:0009889 250 0.044
regulation of primary metabolic process GO:0080090 311 0.044
nucleobase containing compound metabolic process GO:0006139 274 0.044
locomotion GO:0040011 313 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.043
regulation of intracellular protein transport GO:0033157 3 0.042
multicellular organism growth GO:0035264 4 0.042
cellular amine metabolic process GO:0044106 2 0.041
regulation of developmental process GO:0050793 247 0.040
regulation of nucleocytoplasmic transport GO:0046822 2 0.040
death GO:0016265 121 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.039
carboxylic acid metabolic process GO:0019752 22 0.039
organism emergence from protective structure GO:0071684 4 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
cellular response to radiation GO:0071478 4 0.038
regulation of synapse organization GO:0050807 3 0.038
triglyceride homeostasis GO:0070328 2 0.038
protein k48 linked ubiquitination GO:0070936 1 0.037
chromatin modification GO:0016568 21 0.037
regulation of protein import into nucleus GO:0042306 2 0.037
regulation of multicellular organism growth GO:0040014 4 0.036
single organism localization GO:1902578 225 0.036
female sex differentiation GO:0046660 4 0.036
organic substance biosynthetic process GO:1901576 289 0.036
positive regulation of biological process GO:0048518 253 0.036
chromosome organization GO:0051276 31 0.036
stem cell proliferation GO:0072089 4 0.035
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.035
negative regulation of gene expression GO:0010629 65 0.035
regulation of meiotic cell cycle GO:0051445 1 0.035
nucleic acid metabolic process GO:0090304 244 0.034
hematopoietic or lymphoid organ development GO:0048534 191 0.034
protein polymerization GO:0051258 4 0.034
positive regulation of cellular process GO:0048522 201 0.034
oxoacid metabolic process GO:0043436 31 0.034
regulation of cell activation GO:0050865 1 0.034
spindle assembly GO:0051225 2 0.033
cellular component morphogenesis GO:0032989 336 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
regulation of epithelial cell proliferation GO:0050678 3 0.032
cell migration GO:0016477 237 0.032
regulation of protein targeting GO:1903533 2 0.032
negative regulation of rna metabolic process GO:0051253 48 0.032
mitotic cell cycle process GO:1903047 48 0.031
cell motility GO:0048870 244 0.031
lipid storage GO:0019915 1 0.031
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.030
regulation of cytokine production GO:0001817 3 0.030
neuroblast proliferation GO:0007405 2 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.030
transport GO:0006810 220 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
female gonad development GO:0008585 4 0.029
multi organism process GO:0051704 134 0.029
regulation of signal transduction GO:0009966 225 0.028
protein polyubiquitination GO:0000209 4 0.028
mitotic cell cycle GO:0000278 64 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.027
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.027
negative regulation of biological process GO:0048519 304 0.027
protein acetylation GO:0006473 2 0.027
negative regulation of cytoplasmic transport GO:1903650 2 0.027
negative regulation of nuclear division GO:0051784 3 0.027
apoptotic process GO:0006915 116 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
regulation of cell differentiation GO:0045595 142 0.027
microtubule depolymerization GO:0007019 1 0.026
cellular protein catabolic process GO:0044257 4 0.026
cellular localization GO:0051641 97 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
immune system development GO:0002520 191 0.026
regulation of cellular component organization GO:0051128 86 0.025
stem cell maintenance GO:0019827 4 0.025
locomotor rhythm GO:0045475 3 0.025
dna templated transcription elongation GO:0006354 3 0.025
nuclear transport GO:0051169 4 0.025
negative regulation of macromolecule metabolic process GO:0010605 76 0.025
rna processing GO:0006396 25 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.025
negative regulation of transcription dna templated GO:0045892 45 0.025
development of primary female sexual characteristics GO:0046545 4 0.024
regulation of protein complex assembly GO:0043254 3 0.024
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.024
internal peptidyl lysine acetylation GO:0018393 2 0.024
embryonic organ development GO:0048568 381 0.024
oocyte development GO:0048599 14 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
rna localization GO:0006403 4 0.023
response to uv GO:0009411 3 0.023
regulation of protein catabolic process GO:0042176 1 0.023
negative regulation of intracellular transport GO:0032387 3 0.023
regulation of response to stimulus GO:0048583 269 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regulation of multicellular organismal process GO:0051239 277 0.022
adult behavior GO:0030534 2 0.022
negative regulation of defense response GO:0031348 2 0.022
response to stress GO:0006950 263 0.022
response to endogenous stimulus GO:0009719 83 0.022
centrosome cycle GO:0007098 1 0.022
response to external stimulus GO:0009605 264 0.021
blood vessel morphogenesis GO:0048514 216 0.021
organelle assembly GO:0070925 110 0.021
immune system process GO:0002376 241 0.021
regulation of microtubule cytoskeleton organization GO:0070507 3 0.021
establishment of localization GO:0051234 244 0.021
positive regulation of cell cycle GO:0045787 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.020
macromolecule localization GO:0033036 54 0.020
negative regulation of mrna metabolic process GO:1903312 3 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
cytoskeleton organization GO:0007010 96 0.020
positive regulation of transcription dna templated GO:0045893 57 0.020
acylglycerol homeostasis GO:0055090 2 0.020
peptidyl threonine modification GO:0018210 1 0.020
rna export from nucleus GO:0006405 1 0.019
regulation of histone methylation GO:0031060 3 0.019
regulation of synapse assembly GO:0051963 3 0.019
mrna metabolic process GO:0016071 20 0.019
translational initiation GO:0006413 3 0.019
multi organism cellular process GO:0044764 2 0.019
regulation of cell communication GO:0010646 232 0.019
positive regulation of jak stat cascade GO:0046427 2 0.019
intracellular transport GO:0046907 32 0.019
regulation of protein complex disassembly GO:0043244 1 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
organic acid catabolic process GO:0016054 3 0.019
cell cycle GO:0007049 93 0.018
oocyte differentiation GO:0009994 14 0.018
regulation of protein binding GO:0043393 3 0.018
response to hormone GO:0009725 48 0.018
negative regulation of mitosis GO:0045839 3 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
regulation of signaling GO:0023051 235 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
regulation of chromosome segregation GO:0051983 1 0.018
positive regulation of cellular biosynthetic process GO:0031328 68 0.018
macromolecule modification GO:0043412 111 0.018
cellular response to external stimulus GO:0071496 2 0.018
programmed cell death GO:0012501 119 0.018
embryonic heart tube development GO:0035050 133 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
response to organic substance GO:0010033 153 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
protein acylation GO:0043543 3 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
regulation of wound healing GO:0061041 2 0.017
regulation of growth GO:0040008 42 0.017
protein depolymerization GO:0051261 1 0.017
peptidyl lysine methylation GO:0018022 3 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.017
regulation of protein depolymerization GO:1901879 1 0.017
sequestering of calcium ion GO:0051208 3 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
localization of cell GO:0051674 244 0.017
glucose homeostasis GO:0042593 1 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
nucleic acid transport GO:0050657 2 0.017
regulation of dendrite morphogenesis GO:0048814 3 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.017
stem cell division GO:0017145 1 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
compound eye development GO:0048749 2 0.017
protein alkylation GO:0008213 13 0.017
heart development GO:0007507 313 0.017
negative regulation of cytokine production GO:0001818 1 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
cellular component movement GO:0006928 335 0.016
small molecule metabolic process GO:0044281 77 0.016
meiosis i GO:0007127 1 0.016
centrosome organization GO:0051297 1 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
negative regulation of signaling GO:0023057 96 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
negative regulation of rna splicing GO:0033119 1 0.016
regulation of protein metabolic process GO:0051246 56 0.016
negative regulation of kinase activity GO:0033673 4 0.016
microtubule polymerization or depolymerization GO:0031109 3 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
positive regulation of chromosome organization GO:2001252 1 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
negative regulation of cell communication GO:0010648 96 0.016
female meiotic division GO:0007143 2 0.016
microtubule polymerization GO:0046785 2 0.016
generation of neurons GO:0048699 385 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
response to estrogen GO:0043627 27 0.015
developmental process involved in reproduction GO:0003006 27 0.015
interspecies interaction between organisms GO:0044419 4 0.015
regulation of cell cycle GO:0051726 52 0.015
neuron differentiation GO:0030182 353 0.015
regulation of dna templated transcription elongation GO:0032784 3 0.015
cellular protein complex disassembly GO:0043624 1 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cellular response to organic substance GO:0071310 105 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
viral process GO:0016032 1 0.015
male meiosis GO:0007140 2 0.015
cilium organization GO:0044782 71 0.014
sensory organ development GO:0007423 393 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
atp catabolic process GO:0006200 4 0.014
cellular component disassembly GO:0022411 1 0.014
membrane fusion GO:0061025 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regionalization GO:0003002 274 0.014
eye development GO:0001654 277 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
intracellular receptor signaling pathway GO:0030522 30 0.014
macromolecular complex disassembly GO:0032984 1 0.014
response to abiotic stimulus GO:0009628 122 0.014
regulation of microtubule depolymerization GO:0031114 1 0.014
protein complex disassembly GO:0043241 1 0.014
positive regulation of synapse assembly GO:0051965 1 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.014
embryonic skeletal system development GO:0048706 97 0.014
positive regulation of histone modification GO:0031058 1 0.014
developmental growth GO:0048589 166 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
multicellular organism reproduction GO:0032504 35 0.013
microtubule based process GO:0007017 60 0.013
positive regulation of gene expression GO:0010628 71 0.013
chordate embryonic development GO:0043009 271 0.013
protein complex biogenesis GO:0070271 30 0.013
growth GO:0040007 174 0.013
chromosome organization involved in meiosis GO:0070192 1 0.013
regulation of cell death GO:0010941 103 0.013
pole plasm assembly GO:0007315 4 0.013
regulation of apoptotic process GO:0042981 98 0.013
response to hexose GO:0009746 3 0.013
ras protein signal transduction GO:0007265 7 0.013
stem cell development GO:0048864 82 0.013
organelle localization GO:0051640 49 0.013
regulation of organelle organization GO:0033043 29 0.013
embryonic digestive tract development GO:0048566 4 0.013
cellular response to stress GO:0033554 62 0.013
epithelial cell differentiation GO:0030855 116 0.013
regulation of multicellular organismal development GO:2000026 223 0.012
hemopoiesis GO:0030097 183 0.012
monocyte differentiation GO:0030224 2 0.012
angiogenesis GO:0001525 158 0.012
camera type eye development GO:0043010 222 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
homeostasis of number of cells GO:0048872 62 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
tissue remodeling GO:0048771 4 0.012
mrna export from nucleus GO:0006406 1 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
sequestering of metal ion GO:0051238 3 0.012
positive regulation of cell activation GO:0050867 1 0.012
negative regulation of signal transduction GO:0009968 94 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
erythrocyte homeostasis GO:0034101 55 0.012
regulation of gene expression epigenetic GO:0040029 11 0.012
phosphorylation GO:0016310 69 0.012
regulation of cell division GO:0051302 12 0.012
rna 3 end processing GO:0031123 2 0.012
cellular protein localization GO:0034613 20 0.012
cell projection morphogenesis GO:0048858 244 0.012
single organism metabolic process GO:0044710 217 0.012
negative regulation of catabolic process GO:0009895 3 0.012
regulation of binding GO:0051098 3 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
protein heterooligomerization GO:0051291 1 0.012
tube morphogenesis GO:0035239 349 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
cell projection organization GO:0030030 284 0.011
rna polyadenylation GO:0043631 2 0.011
mrna processing GO:0006397 14 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
telomere maintenance GO:0000723 1 0.011
negative regulation of dna replication GO:0008156 2 0.011
positive regulation of developmental process GO:0051094 50 0.011
negative regulation of mrna processing GO:0050686 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
cellular response to light stimulus GO:0071482 4 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
muscle cell differentiation GO:0042692 139 0.011
peptidyl lysine trimethylation GO:0018023 1 0.011
recombinational repair GO:0000725 1 0.011
tube closure GO:0060606 1 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
phototransduction GO:0007602 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
protein modification process GO:0036211 100 0.011
mrna splicing via spliceosome GO:0000398 10 0.011
gamete generation GO:0007276 33 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
response to vitamin GO:0033273 3 0.011
regulation of dendrite development GO:0050773 3 0.011
sensory organ morphogenesis GO:0090596 200 0.011
intracellular mrna localization GO:0008298 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
digestive tract development GO:0048565 265 0.011
germ cell development GO:0007281 22 0.011
cell death GO:0008219 121 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
primary neural tube formation GO:0014020 1 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
response to organic cyclic compound GO:0014070 51 0.011
phosphorus metabolic process GO:0006793 109 0.011
myeloid cell differentiation GO:0030099 86 0.011
peptidyl amino acid modification GO:0018193 16 0.011
b cell activation GO:0042113 2 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
histone h3 k4 methylation GO:0051568 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
positive regulation of chromatin modification GO:1903310 1 0.010
cell morphogenesis GO:0000902 289 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
mitotic metaphase plate congression GO:0007080 1 0.010
meiotic chromosome segregation GO:0045132 3 0.010
small molecule catabolic process GO:0044282 3 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
blood circulation GO:0008015 87 0.010
negative regulation of multi organism process GO:0043901 3 0.010
macromolecular complex assembly GO:0065003 35 0.010
single organism cellular localization GO:1902580 46 0.010

akap8l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.025
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.010
motor neuron disease DOID:231 0 0.010
amyotrophic lateral sclerosis DOID:332 0 0.010
neurodegenerative disease DOID:1289 0 0.010