Danio rerio

0 known processes

alas1

aminolevulinate, delta-, synthetase 1

(Aliases: ALAS-N,wu:fi12g09,wu:fb58d01)

alas1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.364
maintenance of location GO:0051235 4 0.122
lipid storage GO:0019915 1 0.104
response to drug GO:0042493 3 0.076
response to chemical GO:0042221 320 0.065
aging GO:0007568 2 0.062
regulation of metal ion transport GO:0010959 4 0.057
cellular transition metal ion homeostasis GO:0046916 3 0.057
signal transduction GO:0007165 455 0.056
oxoacid metabolic process GO:0043436 31 0.054
regulation of biological quality GO:0065008 263 0.050
organic cyclic compound metabolic process GO:1901360 301 0.048
Zebrafish
membrane lipid biosynthetic process GO:0046467 2 0.046
segmentation GO:0035282 97 0.043
gland development GO:0048732 143 0.042
positive regulation of transport GO:0051050 2 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.041
determination of left right symmetry GO:0007368 179 0.041
single organism metabolic process GO:0044710 217 0.041
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.041
Zebrafish
organic acid metabolic process GO:0006082 31 0.040
cellular ketone metabolic process GO:0042180 11 0.037
cellular response to xenobiotic stimulus GO:0071466 35 0.036
organelle assembly GO:0070925 110 0.036
cellular amino acid metabolic process GO:0006520 7 0.035
digestive tract morphogenesis GO:0048546 231 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.034
programmed cell death GO:0012501 119 0.034
organelle fusion GO:0048284 3 0.033
negative regulation of cellular process GO:0048523 283 0.033
morphogenesis of an epithelium GO:0002009 333 0.032
chordate embryonic development GO:0043009 271 0.032
cellular component movement GO:0006928 335 0.030
positive regulation of cell cycle GO:0045787 3 0.030
response to organic substance GO:0010033 153 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
Zebrafish
regulation of sodium ion transport GO:0002028 2 0.029
immune system development GO:0002520 191 0.029
Zebrafish
er nucleus signaling pathway GO:0006984 2 0.029
death GO:0016265 121 0.028
regulation of protein transport GO:0051223 3 0.028
protein import GO:0017038 3 0.028
negative regulation of metabolic process GO:0009892 86 0.028
cellular amine metabolic process GO:0044106 2 0.028
tube morphogenesis GO:0035239 349 0.028
cellular component biogenesis GO:0044085 178 0.028
regulation of developmental process GO:0050793 247 0.028
meiotic cell cycle process GO:1903046 3 0.028
regulation of multicellular organism growth GO:0040014 4 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
single organism biosynthetic process GO:0044711 71 0.026
Zebrafish
regulation of dna templated transcription in response to stress GO:0043620 0 0.026
mitochondrion organization GO:0007005 4 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
single organism membrane fusion GO:0044801 2 0.025
small molecule metabolic process GO:0044281 77 0.025
negative regulation of biological process GO:0048519 304 0.024
lipid catabolic process GO:0016042 4 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
muscle tissue development GO:0060537 110 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
single organism localization GO:1902578 225 0.024
cellular response to organic substance GO:0071310 105 0.024
multicellular organism growth GO:0035264 4 0.024
ion transport GO:0006811 114 0.024
ameboidal type cell migration GO:0001667 143 0.024
glucose homeostasis GO:0042593 1 0.024
transmembrane transport GO:0055085 120 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.023
cell death GO:0008219 121 0.023
sphingolipid biosynthetic process GO:0030148 2 0.023
central nervous system development GO:0007417 387 0.023
regulation of reproductive process GO:2000241 4 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
embryonic organ development GO:0048568 381 0.023
Zebrafish
medulla oblongata development GO:0021550 4 0.023
regulation of metabolic process GO:0019222 359 0.023
response to topologically incorrect protein GO:0035966 2 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
system process GO:0003008 185 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
adherens junction organization GO:0034332 4 0.022
single organism transport GO:0044765 206 0.022
cellular protein catabolic process GO:0044257 4 0.022
peptide metabolic process GO:0006518 1 0.021
long chain fatty acid metabolic process GO:0001676 1 0.021
axon development GO:0061564 166 0.021
meiotic nuclear division GO:0007126 4 0.021
regulation of protein complex assembly GO:0043254 3 0.020
digestive tract development GO:0048565 265 0.020
single organism organelle organization GO:1902589 199 0.019
protein localization to plasma membrane GO:0072659 1 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
Zebrafish
cell motility GO:0048870 244 0.019
developmental growth GO:0048589 166 0.019
erythrocyte differentiation GO:0030218 54 0.019
membrane fusion GO:0061025 2 0.019
cellular biosynthetic process GO:0044249 286 0.019
Zebrafish
erythrocyte homeostasis GO:0034101 55 0.019
regulation of gene expression GO:0010468 265 0.019
cellular component assembly GO:0022607 170 0.019
negative regulation of developmental process GO:0051093 65 0.018
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
response to stress GO:0006950 263 0.018
amine metabolic process GO:0009308 2 0.018
response to xenobiotic stimulus GO:0009410 45 0.018
protein metabolic process GO:0019538 183 0.018
Zebrafish
adherens junction maintenance GO:0034334 2 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
Zebrafish
establishment of localization GO:0051234 244 0.018
post golgi vesicle mediated transport GO:0006892 1 0.018
biosynthetic process GO:0009058 294 0.018
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
cell junction maintenance GO:0034331 2 0.018
actin filament based process GO:0030029 64 0.018
response to unfolded protein GO:0006986 2 0.018
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.018
organelle organization GO:0006996 227 0.018
sensory organ development GO:0007423 393 0.018
metal ion transport GO:0030001 58 0.018
protein stabilization GO:0050821 2 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
localization of cell GO:0051674 244 0.017
cellular lipid catabolic process GO:0044242 3 0.017
golgi vesicle transport GO:0048193 3 0.017
hemopoiesis GO:0030097 183 0.017
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
response to external stimulus GO:0009605 264 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
protein import into nucleus GO:0006606 3 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
regulation of blood pressure GO:0008217 1 0.016
camera type eye development GO:0043010 222 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
apoptotic process GO:0006915 116 0.016
ion transmembrane transport GO:0034220 91 0.016
cellular component maintenance GO:0043954 3 0.016
regionalization GO:0003002 274 0.016
nuclear import GO:0051170 3 0.016
organic acid catabolic process GO:0016054 3 0.016
muscle structure development GO:0061061 196 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
mesoderm development GO:0007498 88 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of programmed cell death GO:0043067 101 0.015
striated muscle cell development GO:0055002 108 0.015
regulation of apoptotic process GO:0042981 98 0.015
mitochondrial transport GO:0006839 2 0.015
cellular component morphogenesis GO:0032989 336 0.015
response to nutrient GO:0007584 3 0.015
membrane lipid metabolic process GO:0006643 10 0.015
eye development GO:0001654 277 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
gtp metabolic process GO:0046039 4 0.015
cellular response to unfolded protein GO:0034620 2 0.015
hormone biosynthetic process GO:0042446 3 0.015
transcription dna templated GO:0006351 181 0.015
protein polymerization GO:0051258 4 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of glucose import GO:0046324 1 0.014
convergent extension involved in gastrulation GO:0060027 71 0.014
transport GO:0006810 220 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
growth GO:0040007 174 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
digestive system development GO:0055123 289 0.014
regulation of protein polymerization GO:0032271 2 0.014
homeostatic process GO:0042592 142 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
very long chain fatty acid biosynthetic process GO:0042761 4 0.014
stem cell proliferation GO:0072089 4 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
cation transport GO:0006812 81 0.013
cytoskeleton organization GO:0007010 96 0.013
multi organism process GO:0051704 134 0.013
embryonic skeletal system development GO:0048706 97 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
heart development GO:0007507 313 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
peptide transport GO:0015833 1 0.013
liver development GO:0001889 96 0.013
spindle assembly GO:0051225 2 0.013
heterocycle metabolic process GO:0046483 290 0.013
Zebrafish
compound eye development GO:0048749 2 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
centrosome cycle GO:0007098 1 0.013
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.013
sensory organ morphogenesis GO:0090596 200 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
cellular response to hormone stimulus GO:0032870 39 0.013
cellular sodium ion homeostasis GO:0006883 1 0.013
specification of symmetry GO:0009799 204 0.012
cell substrate junction assembly GO:0007044 2 0.012
gene expression GO:0010467 252 0.012
centrosome organization GO:0051297 1 0.012
mitotic cell cycle GO:0000278 64 0.012
hormone transport GO:0009914 2 0.012
cell morphogenesis GO:0000902 289 0.012
rna metabolic process GO:0016070 219 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
regulation of calcium ion transport GO:0051924 2 0.012
metal ion homeostasis GO:0055065 26 0.012
cell migration GO:0016477 237 0.012
positive regulation of catabolic process GO:0009896 4 0.012
cellular modified amino acid metabolic process GO:0006575 3 0.012
locomotion GO:0040011 313 0.012
p38mapk cascade GO:0038066 1 0.012
action potential GO:0001508 19 0.012
nucleic acid templated transcription GO:0097659 181 0.012
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
blood vessel morphogenesis GO:0048514 216 0.012
glucose import GO:0046323 2 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
appendage development GO:0048736 80 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
myeloid cell homeostasis GO:0002262 56 0.011
regulation of blood vessel size GO:0050880 2 0.011
germ line stem cell maintenance GO:0030718 2 0.011
adult behavior GO:0030534 2 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
neural nucleus development GO:0048857 15 0.011
regulation of synapse organization GO:0050807 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
response to biotic stimulus GO:0009607 97 0.011
protein targeting to nucleus GO:0044744 3 0.011
response to endogenous stimulus GO:0009719 83 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of tube size GO:0035150 2 0.011
lipid oxidation GO:0034440 1 0.011
cell proliferation GO:0008283 80 0.010
mesenchyme development GO:0060485 127 0.010
muscle organ development GO:0007517 101 0.010
microtubule based process GO:0007017 60 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
fatty acid elongation GO:0030497 1 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
regulation of developmental growth GO:0048638 38 0.010
zymogen activation GO:0031638 3 0.010
negative regulation of reproductive process GO:2000242 3 0.010
anterior posterior pattern specification GO:0009952 152 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
Zebrafish
microtubule cytoskeleton organization GO:0000226 33 0.010
intracellular signal transduction GO:0035556 85 0.010
regulation of cell death GO:0010941 103 0.010
determination of bilateral symmetry GO:0009855 204 0.010
negative regulation of rna splicing GO:0033119 1 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
phagocytosis GO:0006909 3 0.010
positive regulation of epithelial cell migration GO:0010634 2 0.010

alas1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
organ system cancer DOID:0050686 0 0.014