Danio rerio

0 known processes

aldob

aldolase b, fructose-bisphosphate

(Aliases: fb25f09,wu:fb25f09)

aldob biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to chemical GO:0042221 320 0.607
cellular response to steroid hormone stimulus GO:0071383 31 0.507
lipid storage GO:0019915 1 0.473
cellular amide metabolic process GO:0043603 4 0.460
long chain fatty acid transport GO:0015909 1 0.459
alpha amino acid metabolic process GO:1901605 3 0.446
response to steroid hormone GO:0048545 35 0.433
response to organic cyclic compound GO:0014070 51 0.384
pectoral fin development GO:0033339 50 0.348
cellular response to organic cyclic compound GO:0071407 38 0.299
maintenance of location GO:0051235 4 0.299
organic acid metabolic process GO:0006082 31 0.253
aging GO:0007568 2 0.245
response to nutrient GO:0007584 3 0.228
liver development GO:0001889 96 0.221
response to estrogen GO:0043627 27 0.218
signal transduction GO:0007165 455 0.214
response to organic substance GO:0010033 153 0.208
larval development GO:0002164 2 0.190
response to stress GO:0006950 263 0.183
cellular response to estrogen stimulus GO:0071391 24 0.159
response to endogenous stimulus GO:0009719 83 0.152
water homeostasis GO:0030104 4 0.152
regulation of hormone levels GO:0010817 21 0.148
oxoacid metabolic process GO:0043436 31 0.142
cellular response to xenobiotic stimulus GO:0071466 35 0.133
pancreas development GO:0031016 84 0.131
regulation of biological quality GO:0065008 263 0.125
cellular response to organic substance GO:0071310 105 0.124
lymphatic endothelial cell fate commitment GO:0060838 1 0.117
innate immune response GO:0045087 13 0.116
locomotion GO:0040011 313 0.115
Zebrafish Worm
acylglycerol homeostasis GO:0055090 2 0.112
cellular nitrogen compound metabolic process GO:0034641 290 0.111
hormone transport GO:0009914 2 0.111
carboxylic acid metabolic process GO:0019752 22 0.106
cellular response to endogenous stimulus GO:0071495 68 0.104
regulation of nitrogen compound metabolic process GO:0051171 251 0.102
regulation of hormone secretion GO:0046883 2 0.099
cellular response to lipid GO:0071396 39 0.096
heart looping GO:0001947 94 0.093
positive regulation of cellular catabolic process GO:0031331 3 0.093
skeletal system development GO:0001501 181 0.092
hatching gland development GO:0048785 3 0.091
response to lipid GO:0033993 60 0.090
multicellular organism growth GO:0035264 4 0.090
hormone secretion GO:0046879 2 0.089
cellular response to chemical stimulus GO:0070887 157 0.089
cellular modified amino acid metabolic process GO:0006575 3 0.088
embryonic organ development GO:0048568 381 0.088
regulation of transcription dna templated GO:0006355 213 0.087
single organism localization GO:1902578 225 0.085
regulation of fatty acid metabolic process GO:0019217 1 0.085
xenobiotic metabolic process GO:0006805 4 0.084
cellular amino acid metabolic process GO:0006520 7 0.083
regulation of primary metabolic process GO:0080090 311 0.083
cellular macromolecule metabolic process GO:0044260 391 0.081
heterocycle metabolic process GO:0046483 290 0.077
single organism metabolic process GO:0044710 217 0.075
epithelial cell differentiation GO:0030855 116 0.074
gene expression GO:0010467 252 0.074
morphogenesis of an epithelium GO:0002009 333 0.073
response to xenobiotic stimulus GO:0009410 45 0.073
cellular localization GO:0051641 97 0.073
regulation of inflammatory response GO:0050727 2 0.069
regulation of rna biosynthetic process GO:2001141 213 0.069
hepaticobiliary system development GO:0061008 98 0.068
sensory organ morphogenesis GO:0090596 200 0.068
monocarboxylic acid metabolic process GO:0032787 17 0.068
negative regulation of defense response GO:0031348 2 0.068
gland development GO:0048732 143 0.067
cellular lipid metabolic process GO:0044255 36 0.066
positive regulation of cellular process GO:0048522 201 0.065
response to hormone GO:0009725 48 0.065
cellular response to hormone stimulus GO:0032870 39 0.065
fat soluble vitamin metabolic process GO:0006775 4 0.065
transport GO:0006810 220 0.064
negative regulation of epithelial cell proliferation GO:0050680 1 0.062
ossification GO:0001503 23 0.060
inflammatory response GO:0006954 8 0.059
regulation of epithelial cell proliferation GO:0050678 3 0.059
regulation of macromolecule metabolic process GO:0060255 317 0.059
regulation of metabolic process GO:0019222 359 0.059
carboxylic acid catabolic process GO:0046395 3 0.056
cellular response to nutrient levels GO:0031669 2 0.056
generation of neurons GO:0048699 385 0.056
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.056
hindbrain development GO:0030902 91 0.055
organic acid catabolic process GO:0016054 3 0.055
regulation of membrane potential GO:0042391 23 0.054
intestinal absorption GO:0050892 2 0.053
cellular amino acid biosynthetic process GO:0008652 2 0.052
epithelial cell development GO:0002064 42 0.052
response to vitamin GO:0033273 3 0.050
nucleobase containing compound metabolic process GO:0006139 274 0.049
camera type eye development GO:0043010 222 0.048
lateral line system development GO:0048925 76 0.048
vitamin a metabolic process GO:0006776 1 0.047
aromatic compound biosynthetic process GO:0019438 217 0.046
transcription from rna polymerase iii promoter GO:0006383 1 0.046
sensory organ development GO:0007423 393 0.046
cellular ketone metabolic process GO:0042180 11 0.046
negative regulation of cellular process GO:0048523 283 0.046
cellular macromolecule biosynthetic process GO:0034645 224 0.046
response to drug GO:0042493 3 0.046
establishment of localization GO:0051234 244 0.045
regulation of multicellular organism growth GO:0040014 4 0.045
fin development GO:0033333 77 0.045
triglyceride homeostasis GO:0070328 2 0.045
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.044
biosynthetic process GO:0009058 294 0.043
lymphatic endothelial cell differentiation GO:0060836 1 0.043
cellular response to external stimulus GO:0071496 2 0.042
regulation of transferase activity GO:0051338 16 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.042
organic cyclic compound metabolic process GO:1901360 301 0.041
homeostatic process GO:0042592 142 0.040
negative regulation of hormone secretion GO:0046888 2 0.039
response to acid chemical GO:0001101 17 0.039
nucleic acid templated transcription GO:0097659 181 0.038
heart development GO:0007507 313 0.038
peptide transport GO:0015833 1 0.038
negative regulation of secretion by cell GO:1903531 2 0.038
cellular hormone metabolic process GO:0034754 19 0.038
defense response GO:0006952 47 0.038
activation of immune response GO:0002253 9 0.038
regulation of jun kinase activity GO:0043506 3 0.038
digestive tract development GO:0048565 265 0.037
amide biosynthetic process GO:0043604 1 0.037
hematopoietic or lymphoid organ development GO:0048534 191 0.037
small molecule metabolic process GO:0044281 77 0.037
pectoral fin morphogenesis GO:0035138 29 0.036
digestive system development GO:0055123 289 0.036
cellular response to starvation GO:0009267 1 0.036
retinoid metabolic process GO:0001523 15 0.036
eye morphogenesis GO:0048592 144 0.035
regulation of cytokine production GO:0001817 3 0.035
branched chain amino acid metabolic process GO:0009081 1 0.035
cerebellar granular layer formation GO:0021684 3 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
fatty acid transport GO:0015908 1 0.034
central nervous system development GO:0007417 387 0.033
Zebrafish
regulation of protein metabolic process GO:0051246 56 0.033
embryonic organ morphogenesis GO:0048562 274 0.033
embryonic pectoral fin morphogenesis GO:0035118 24 0.033
positive regulation of catabolic process GO:0009896 4 0.032
optic placode formation GO:0001743 4 0.032
nucleic acid metabolic process GO:0090304 244 0.032
cerebellar granular layer development GO:0021681 3 0.032
cerebellum development GO:0021549 17 0.032
immune response GO:0006955 28 0.032
regulation of multicellular organismal process GO:0051239 277 0.032
tube morphogenesis GO:0035239 349 0.031
sulfur compound metabolic process GO:0006790 13 0.030
lipid catabolic process GO:0016042 4 0.030
nitrogen compound metabolic process GO:0006807 319 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
regulation of cell substrate adhesion GO:0010810 1 0.030
skeletal system morphogenesis GO:0048705 102 0.030
hindbrain morphogenesis GO:0021575 22 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
epidermal cell fate specification GO:0009957 4 0.029
organic substance biosynthetic process GO:1901576 289 0.029
retina development in camera type eye GO:0060041 146 0.029
heterocycle biosynthetic process GO:0018130 215 0.028
hepatocyte differentiation GO:0070365 1 0.028
circulatory system process GO:0003013 87 0.028
response to starvation GO:0042594 5 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
cell differentiation in hindbrain GO:0021533 5 0.028
intestinal cholesterol absorption GO:0030299 2 0.028
regulation of cell differentiation GO:0045595 142 0.028
cellular biosynthetic process GO:0044249 286 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
sensory system development GO:0048880 76 0.027
response to wounding GO:0009611 116 0.027
female sex differentiation GO:0046660 4 0.027
cellular component morphogenesis GO:0032989 336 0.027
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.027
lipid digestion GO:0044241 3 0.027
cellular amine metabolic process GO:0044106 2 0.026
secondary metabolic process GO:0019748 3 0.026
endocrine pancreas development GO:0031018 27 0.026
brain development GO:0007420 293 0.026
Zebrafish
immune system process GO:0002376 241 0.026
protein modification process GO:0036211 100 0.026
regulation of epidermis development GO:0045682 2 0.025
response to vitamin b3 GO:0033552 2 0.025
anion transport GO:0006820 38 0.025
regulation of anatomical structure morphogenesis GO:0022603 130 0.025
cation transport GO:0006812 81 0.024
positive regulation of biological process GO:0048518 253 0.024
regulation of rna metabolic process GO:0051252 224 0.024
response to oxygen containing compound GO:1901700 55 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
cellular catabolic process GO:0044248 27 0.024
regulation of response to stimulus GO:0048583 269 0.024
negative regulation of secretion GO:0051048 2 0.024
organelle organization GO:0006996 227 0.023
acyl coa metabolic process GO:0006637 1 0.023
cellular response to prostaglandin stimulus GO:0071379 3 0.023
small molecule biosynthetic process GO:0044283 16 0.023
regulation of gene expression GO:0010468 265 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
amine metabolic process GO:0009308 2 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
regulation of metal ion transport GO:0010959 4 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
endocrine system development GO:0035270 65 0.022
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.022
peptide metabolic process GO:0006518 1 0.021
terpenoid metabolic process GO:0006721 15 0.021
dicarboxylic acid metabolic process GO:0043648 1 0.021
gtp metabolic process GO:0046039 4 0.021
oxidation reduction process GO:0055114 41 0.020
rna biosynthetic process GO:0032774 181 0.020
protein import GO:0017038 3 0.020
regulation of apoptotic process GO:0042981 98 0.020
long chain fatty acid metabolic process GO:0001676 1 0.020
monocarboxylic acid catabolic process GO:0072329 3 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
protein localization to plasma membrane GO:0072659 1 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
growth GO:0040007 174 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
keratinocyte differentiation GO:0030216 0 0.020
inner ear morphogenesis GO:0042472 63 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
regulation of defense response GO:0031347 14 0.019
small molecule catabolic process GO:0044282 3 0.019
response to external stimulus GO:0009605 264 0.019
Zebrafish
inner ear development GO:0048839 126 0.019
regulation of catalytic activity GO:0050790 55 0.019
retinoic acid receptor signaling pathway GO:0048384 16 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
ear morphogenesis GO:0042471 64 0.019
response to nitrogen compound GO:1901698 19 0.019
camera type eye morphogenesis GO:0048593 108 0.019
negative regulation of kinase activity GO:0033673 4 0.018
response to extracellular stimulus GO:0009991 10 0.018
cerebellar granule cell differentiation GO:0021707 3 0.018
epidermis development GO:0008544 48 0.018
positive regulation of nucleic acid templated transcription GO:1903508 57 0.018
response to carbohydrate GO:0009743 3 0.018
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
positive regulation of translation GO:0045727 1 0.017
organic acid biosynthetic process GO:0016053 12 0.017
positive regulation of transport GO:0051050 2 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
skin development GO:0043588 54 0.017
hepatocyte proliferation GO:0072574 2 0.017
neural crest cell differentiation GO:0014033 72 0.017
ion transport GO:0006811 114 0.017
organic substance catabolic process GO:1901575 28 0.017
heart contraction GO:0060047 71 0.017
nerve development GO:0021675 45 0.017
multi organism process GO:0051704 134 0.017
Worm
regulation of carbohydrate metabolic process GO:0006109 4 0.017
gtp catabolic process GO:0006184 2 0.017
diterpenoid biosynthetic process GO:0016102 7 0.017
lens morphogenesis in camera type eye GO:0002089 7 0.017
axon ensheathment in central nervous system GO:0032291 2 0.017
regulation of jak stat cascade GO:0046425 3 0.017
epithelial cell proliferation GO:0050673 17 0.017
toxin metabolic process GO:0009404 1 0.016
muscle structure development GO:0061061 196 0.016
diterpenoid metabolic process GO:0016101 15 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
gastrulation GO:0007369 208 0.016
protein metabolic process GO:0019538 183 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
Zebrafish
single organism transport GO:0044765 206 0.016
epithelial cell fate commitment GO:0072148 11 0.016
bone remodeling GO:0046849 2 0.016
morphogenesis of embryonic epithelium GO:0016331 30 0.016
establishment of localization in cell GO:0051649 77 0.016
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.016
response to nutrient levels GO:0031667 10 0.015
regulation of dna methylation GO:0044030 5 0.015
determination of left right symmetry GO:0007368 179 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
carboxylic acid biosynthetic process GO:0046394 12 0.015
regulation of circadian sleep wake cycle GO:0042749 1 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
membrane repolarization GO:0086009 2 0.015
adherens junction organization GO:0034332 4 0.015
multicellular organismal response to stress GO:0033555 2 0.015
cellular protein metabolic process GO:0044267 129 0.015
lateral line development GO:0048882 66 0.015
aflatoxin b1 metabolic process GO:0043390 1 0.014
developmental growth GO:0048589 166 0.014
cellular lipid catabolic process GO:0044242 3 0.014
amide transport GO:0042886 12 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
regulation of neuron migration GO:2001222 2 0.014
atrioventricular valve formation GO:0003190 3 0.014
positive regulation of neuron migration GO:2001224 2 0.014
negative regulation of biological process GO:0048519 304 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
negative regulation of bmp signaling pathway GO:0030514 13 0.014
hematopoietic stem cell migration GO:0035701 4 0.013
rna metabolic process GO:0016070 219 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
regulation of developmental process GO:0050793 247 0.013
somite development GO:0061053 96 0.013
Zebrafish
macromolecule modification GO:0043412 111 0.013
positive regulation of metabolic process GO:0009893 108 0.013
protein stabilization GO:0050821 2 0.013
mitochondrial transport GO:0006839 2 0.013
negative regulation of cytokine production GO:0001818 1 0.013
response to food GO:0032094 1 0.013
regulation of glial cell differentiation GO:0045685 4 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
organic substance transport GO:0071702 58 0.013
regulation of biosynthetic process GO:0009889 250 0.013
phagocytosis GO:0006909 3 0.013
transcription dna templated GO:0006351 181 0.013
regulation of tissue remodeling GO:0034103 2 0.013
mesenchymal cell development GO:0014031 78 0.013
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.012
digestive system process GO:0022600 9 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
cerebellar granular layer morphogenesis GO:0021683 3 0.012
regulation of protein polymerization GO:0032271 2 0.012
neuromast development GO:0048884 46 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
regulation of cardiac muscle cell contraction GO:0086004 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
fat soluble vitamin biosynthetic process GO:0042362 2 0.012
catabolic process GO:0009056 32 0.012
regulation of kinase activity GO:0043549 15 0.012
regulation of cell death GO:0010941 103 0.012
epidermal cell differentiation GO:0009913 36 0.012
hemopoiesis GO:0030097 183 0.012
programmed cell death GO:0012501 119 0.012
regulation of cell projection assembly GO:0060491 4 0.012
neurotransmitter transport GO:0006836 2 0.011
myeloid cell development GO:0061515 32 0.011
neuron differentiation GO:0030182 353 0.011
Zebrafish
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.011
proteolysis GO:0006508 38 0.011
isoprenoid metabolic process GO:0006720 15 0.011
otic vesicle formation GO:0030916 27 0.011
regulation of immune system process GO:0002682 34 0.011
central nervous system myelin formation GO:0032289 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regeneration GO:0031099 91 0.011
axis elongation involved in somitogenesis GO:0090245 2 0.011
lipid homeostasis GO:0055088 3 0.011
leukocyte differentiation GO:0002521 25 0.011
cellular response to fatty acid GO:0071398 3 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
specification of symmetry GO:0009799 204 0.011
heart morphogenesis GO:0003007 156 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.010
positive regulation of carbohydrate metabolic process GO:0045913 1 0.010
lipid localization GO:0010876 11 0.010
single organism biosynthetic process GO:0044711 71 0.010
dna modification GO:0006304 8 0.010
vitamin biosynthetic process GO:0009110 2 0.010
somitogenesis GO:0001756 87 0.010
Zebrafish
positive regulation of secretion GO:0051047 1 0.010
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.010

aldob disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.420
inherited metabolic disorder DOID:655 0 0.420
disease of anatomical entity DOID:7 0 0.148
diabetes mellitus DOID:9351 0 0.034
type 2 diabetes mellitus DOID:9352 0 0.034
carbohydrate metabolism disease DOID:0050013 0 0.034
glucose metabolism disease DOID:4194 0 0.034
acquired metabolic disease DOID:0060158 0 0.034
nervous system disease DOID:863 0 0.020
cardiovascular system disease DOID:1287 0 0.017
lysosomal storage disease DOID:3211 0 0.014
disease of mental health DOID:150 0 0.014
developmental disorder of mental health DOID:0060037 0 0.014
lipid metabolism disorder DOID:3146 0 0.010