Danio rerio

0 known processes

amfr

autocrine motility factor receptor

(Aliases: zgc:63893,wu:fi06e06,wu:fi37e05)

amfr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.135
lipid oxidation GO:0034440 1 0.090
maintenance of location GO:0051235 4 0.089
carboxylic acid catabolic process GO:0046395 3 0.084
cellular ketone metabolic process GO:0042180 11 0.079
single organism metabolic process GO:0044710 217 0.072
phagocytosis GO:0006909 3 0.070
regulation of protein complex assembly GO:0043254 3 0.065
small molecule metabolic process GO:0044281 77 0.062
lipid catabolic process GO:0016042 4 0.060
larval development GO:0002164 2 0.058
organelle organization GO:0006996 227 0.057
organic acid catabolic process GO:0016054 3 0.056
establishment of protein localization to organelle GO:0072594 4 0.056
small molecule catabolic process GO:0044282 3 0.055
oxoacid metabolic process GO:0043436 31 0.054
cellular lipid catabolic process GO:0044242 3 0.053
positive regulation of transport GO:0051050 2 0.049
fatty acid catabolic process GO:0009062 1 0.049
organic acid metabolic process GO:0006082 31 0.047
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.047
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.047
fatty acid beta oxidation GO:0006635 1 0.047
fatty acid oxidation GO:0019395 1 0.046
transport GO:0006810 220 0.045
proteasomal protein catabolic process GO:0010498 2 0.044
Human
morphogenesis of an epithelium GO:0002009 333 0.044
establishment of localization GO:0051234 244 0.043
regulation of multicellular organism growth GO:0040014 4 0.042
protein metabolic process GO:0019538 183 0.041
Human
response to chemical GO:0042221 320 0.040
Human
regulation of biological quality GO:0065008 263 0.040
negative regulation of catabolic process GO:0009895 3 0.039
regulation of protein catabolic process GO:0042176 1 0.038
carboxylic acid metabolic process GO:0019752 22 0.037
axon development GO:0061564 166 0.037
amine metabolic process GO:0009308 2 0.036
tube morphogenesis GO:0035239 349 0.036
negative regulation of biological process GO:0048519 304 0.036
lipid storage GO:0019915 1 0.036
negative regulation of protein complex assembly GO:0031333 1 0.035
cell surface receptor signaling pathway GO:0007166 325 0.035
positive regulation of catabolic process GO:0009896 4 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
Human
cell projection organization GO:0030030 284 0.034
protein polymerization GO:0051258 4 0.033
signal transduction GO:0007165 455 0.033
Human
cellular amine metabolic process GO:0044106 2 0.033
cellular component biogenesis GO:0044085 178 0.032
Human
regionalization GO:0003002 274 0.032
protein import GO:0017038 3 0.032
digestive tract morphogenesis GO:0048546 231 0.032
single organism localization GO:1902578 225 0.032
monocarboxylic acid catabolic process GO:0072329 3 0.031
multicellular organism growth GO:0035264 4 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
cellular component assembly GO:0022607 170 0.030
Human
regulation of fatty acid metabolic process GO:0019217 1 0.030
microtubule organizing center organization GO:0031023 1 0.028
vasculature development GO:0001944 278 0.028
organonitrogen compound metabolic process GO:1901564 74 0.027
cellular respiration GO:0045333 3 0.026
meiotic nuclear division GO:0007126 4 0.026
regulation of response to stimulus GO:0048583 269 0.026
regulation of rna metabolic process GO:0051252 224 0.026
sensory perception of chemical stimulus GO:0007606 3 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
digestive tract development GO:0048565 265 0.025
centrosome organization GO:0051297 1 0.024
golgi vesicle transport GO:0048193 3 0.024
cellular protein catabolic process GO:0044257 4 0.024
Human
gtp metabolic process GO:0046039 4 0.024
cellular component movement GO:0006928 335 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
regulation of cell communication GO:0010646 232 0.024
modification dependent protein catabolic process GO:0019941 3 0.023
Human
autophagy GO:0006914 4 0.023
oxidation reduction process GO:0055114 41 0.023
gastrulation GO:0007369 208 0.022
cellular amide metabolic process GO:0043603 4 0.022
gene expression GO:0010467 252 0.022
centrosome cycle GO:0007098 1 0.022
cell morphogenesis GO:0000902 289 0.022
actin polymerization or depolymerization GO:0008154 2 0.022
determination of left right symmetry GO:0007368 179 0.022
hormone transport GO:0009914 2 0.022
positive regulation of cell cycle GO:0045787 3 0.022
cell projection morphogenesis GO:0048858 244 0.021
organic substance biosynthetic process GO:1901576 289 0.021
sensory organ morphogenesis GO:0090596 200 0.021
cellular response to starvation GO:0009267 1 0.021
positive regulation of map kinase activity GO:0043406 3 0.021
dicarboxylic acid metabolic process GO:0043648 1 0.021
carbohydrate biosynthetic process GO:0016051 1 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
cellular biosynthetic process GO:0044249 286 0.021
regulation of tube size GO:0035150 2 0.021
stem cell proliferation GO:0072089 4 0.020
adult behavior GO:0030534 2 0.020
sensory organ development GO:0007423 393 0.020
circadian sleep wake cycle sleep GO:0050802 1 0.020
regulation of circadian rhythm GO:0042752 4 0.020
regulation of lipid catabolic process GO:0050994 2 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
mitochondrion organization GO:0007005 4 0.020
cognition GO:0050890 1 0.020
regulation of signal transduction GO:0009966 225 0.020
circadian sleep wake cycle process GO:0022410 2 0.020
brain development GO:0007420 293 0.020
cellular response to external stimulus GO:0071496 2 0.020
cellular protein modification process GO:0006464 100 0.020
Human
chordate embryonic development GO:0043009 271 0.020
synaptic vesicle transport GO:0048489 1 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
tissue remodeling GO:0048771 4 0.019
meiotic cell cycle process GO:1903046 3 0.019
g protein coupled receptor signaling pathway GO:0007186 74 0.019
macromolecule modification GO:0043412 111 0.019
Human
eye development GO:0001654 277 0.019
growth GO:0040007 174 0.019
cell part morphogenesis GO:0032990 246 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
primary neural tube formation GO:0014020 1 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
single organism transport GO:0044765 206 0.018
digestive system development GO:0055123 289 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
central nervous system development GO:0007417 387 0.018
muscle structure development GO:0061061 196 0.018
positive regulation of secretion GO:0051047 1 0.018
hormone secretion GO:0046879 2 0.018
protein complex biogenesis GO:0070271 30 0.018
Human
cellular component morphogenesis GO:0032989 336 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
regulation of synaptic plasticity GO:0048167 1 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
Human
regulation of organ growth GO:0046620 3 0.017
embryonic organ development GO:0048568 381 0.017
membrane invagination GO:0010324 1 0.017
response to drug GO:0042493 3 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
regulation of signaling GO:0023051 235 0.017
protein homooligomerization GO:0051260 3 0.017
positive regulation of biological process GO:0048518 253 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
organelle assembly GO:0070925 110 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
regulation of carbohydrate metabolic process GO:0006109 4 0.016
stem cell division GO:0017145 1 0.016
biosynthetic process GO:0009058 294 0.016
leukocyte homeostasis GO:0001776 2 0.016
regulation of hormone secretion GO:0046883 2 0.016
alpha amino acid metabolic process GO:1901605 3 0.016
blood vessel morphogenesis GO:0048514 216 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
cellular response to topologically incorrect protein GO:0035967 2 0.016
Human
actin filament polymerization GO:0030041 2 0.016
blood vessel development GO:0001568 246 0.016
gtp catabolic process GO:0006184 2 0.016
regulation of jak stat cascade GO:0046425 3 0.016
cellular transition metal ion homeostasis GO:0046916 3 0.016
catabolic process GO:0009056 32 0.016
Human
axonogenesis GO:0007409 152 0.015
regulation of protein transport GO:0051223 3 0.015
regulation of synapse organization GO:0050807 3 0.015
regulation of synapse assembly GO:0051963 3 0.015
neuron development GO:0048666 262 0.015
protein complex assembly GO:0006461 30 0.015
Human
negative regulation of cellular process GO:0048523 283 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.015
protein localization to nucleus GO:0034504 3 0.015
regulation of reproductive process GO:2000241 4 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of primary metabolic process GO:0080090 311 0.015
lateral inhibition GO:0046331 1 0.015
regulation of binding GO:0051098 3 0.015
germ line stem cell maintenance GO:0030718 2 0.015
macromolecule localization GO:0033036 54 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
neuroblast proliferation GO:0007405 2 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.015
regulation of fatty acid oxidation GO:0046320 1 0.015
regulation of cellular component organization GO:0051128 86 0.015
cell migration involved in gastrulation GO:0042074 79 0.015
determination of bilateral symmetry GO:0009855 204 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
protein modification by small protein removal GO:0070646 1 0.014
mitotic g2 m transition checkpoint GO:0044818 3 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
protein secretion GO:0009306 1 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
regulation of blood vessel size GO:0050880 2 0.014
specification of symmetry GO:0009799 204 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
positive regulation of blood circulation GO:1903524 2 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
connective tissue development GO:0061448 99 0.014
cellular protein metabolic process GO:0044267 129 0.014
Human
cell substrate adhesion GO:0031589 4 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
regulation of cell shape GO:0008360 1 0.014
segmentation GO:0035282 97 0.014
establishment of localization in cell GO:0051649 77 0.013
negative regulation of cell communication GO:0010648 96 0.013
golgi organization GO:0007030 1 0.013
macromolecular complex disassembly GO:0032984 1 0.013
spindle assembly GO:0051225 2 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
lipid metabolic process GO:0006629 52 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.013
germ line stem cell division GO:0042078 1 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
phosphorus metabolic process GO:0006793 109 0.013
cartilage development GO:0051216 96 0.013
liver development GO:0001889 96 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
atp synthesis coupled electron transport GO:0042773 1 0.013
response to light stimulus GO:0009416 46 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
protein acetylation GO:0006473 2 0.013
response to uv GO:0009411 3 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
regulation of intracellular ph GO:0051453 1 0.013
mesenchymal cell proliferation GO:0010463 1 0.013
homeostatic process GO:0042592 142 0.013
synaptic vesicle recycling GO:0036465 1 0.013
striated muscle cell differentiation GO:0051146 129 0.013
membrane fusion GO:0061025 2 0.013
localization of cell GO:0051674 244 0.013
negative regulation of signal transduction GO:0009968 94 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
response to alkaloid GO:0043279 2 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
response to stress GO:0006950 263 0.012
Human
somatic muscle development GO:0007525 4 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of circadian sleep wake cycle GO:0042749 1 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
negative regulation of cytokine production GO:0001818 1 0.012
protein acylation GO:0043543 3 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
system process GO:0003008 185 0.012
regulation of protein polymerization GO:0032271 2 0.012
nuclear transport GO:0051169 4 0.012
cell migration GO:0016477 237 0.012
nuclear import GO:0051170 3 0.012
developmental growth GO:0048589 166 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
peptide transport GO:0015833 1 0.012
tube closure GO:0060606 1 0.012
organic substance transport GO:0071702 58 0.012
long chain fatty acid metabolic process GO:0001676 1 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
anterior posterior pattern specification GO:0009952 152 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
macroautophagy GO:0016236 1 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
ion homeostasis GO:0050801 41 0.011
nucleic acid transport GO:0050657 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
intracellular signal transduction GO:0035556 85 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
response to nutrient GO:0007584 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
mitotic g2 dna damage checkpoint GO:0007095 3 0.011
protein localization to plasma membrane GO:0072659 1 0.011
centrosome duplication GO:0051298 1 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
dicarboxylic acid transport GO:0006835 1 0.011
hemopoiesis GO:0030097 183 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
locomotion GO:0040011 313 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of transcription dna templated GO:0006355 213 0.011
macromolecular complex assembly GO:0065003 35 0.011
Human
cellular lipid metabolic process GO:0044255 36 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
transmembrane transport GO:0055085 120 0.011
single organism nuclear import GO:1902593 3 0.011
eye morphogenesis GO:0048592 144 0.011
heart looping GO:0001947 94 0.011
stem cell maintenance GO:0019827 4 0.011
protein import into nucleus GO:0006606 3 0.011
regulation of localization GO:0032879 104 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
microtubule polymerization or depolymerization GO:0031109 3 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
Human
iron ion homeostasis GO:0055072 4 0.011
cell growth GO:0016049 57 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
protein targeting to membrane GO:0006612 1 0.011
cellular response to nutrient levels GO:0031669 2 0.011
cellular localization GO:0051641 97 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
single organism organelle organization GO:1902589 199 0.011
cytokinesis GO:0000910 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.010
cellular response to radiation GO:0071478 4 0.010
regulation of jun kinase activity GO:0043506 3 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
compound eye development GO:0048749 2 0.010
circadian sleep wake cycle GO:0042745 2 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
regulation of inflammatory response GO:0050727 2 0.010
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.010
response to hydrogen peroxide GO:0042542 3 0.010
neuron remodeling GO:0016322 1 0.010
organelle fusion GO:0048284 3 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
rna biosynthetic process GO:0032774 181 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
Human
establishment of vesicle localization GO:0051650 24 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
head development GO:0060322 303 0.010
carbohydrate homeostasis GO:0033500 1 0.010
microtubule based process GO:0007017 60 0.010
camera type eye development GO:0043010 222 0.010
sensory perception of smell GO:0007608 2 0.010
rna export from nucleus GO:0006405 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010

amfr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.039
disease of metabolism DOID:0014667 0 0.027
lipid storage disease DOID:9455 0 0.018
lysosomal storage disease DOID:3211 0 0.018
inherited metabolic disorder DOID:655 0 0.018
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
heart disease DOID:114 0 0.011
cardiomyopathy DOID:0050700 0 0.011
cardiovascular system disease DOID:1287 0 0.011
musculoskeletal system disease DOID:17 0 0.011
muscle tissue disease DOID:66 0 0.011