Danio rerio

0 known processes

angptl3

angiopoietin-like 3

(Aliases: fb66h02,wu:fb66h02,zgc:111943,fb60e11,wu:fb60e11)

angptl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism metabolic process GO:0044710 217 0.193
Human Zebrafish
meiotic nuclear division GO:0007126 4 0.180
positive regulation of transport GO:0051050 2 0.147
immune system development GO:0002520 191 0.143
larval development GO:0002164 2 0.113
organic acid catabolic process GO:0016054 3 0.113
response to carbohydrate GO:0009743 3 0.112
autophagy GO:0006914 4 0.100
response to alkaloid GO:0043279 2 0.097
cellular response to xenobiotic stimulus GO:0071466 35 0.096
cellular component morphogenesis GO:0032989 336 0.092
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.088
lipid homeostasis GO:0055088 3 0.087
aging GO:0007568 2 0.086
maintenance of location GO:0051235 4 0.085
negative regulation of neural precursor cell proliferation GO:2000178 1 0.085
establishment of localization GO:0051234 244 0.084
neuron development GO:0048666 262 0.079
response to hexose GO:0009746 3 0.076
hormone transport GO:0009914 2 0.076
long chain fatty acid metabolic process GO:0001676 1 0.074
growth GO:0040007 174 0.073
cognition GO:0050890 1 0.070
regulation of multicellular organism growth GO:0040014 4 0.069
mononuclear cell proliferation GO:0032943 1 0.069
carboxylic acid catabolic process GO:0046395 3 0.067
lipid storage GO:0019915 1 0.066
cellular catabolic process GO:0044248 27 0.065
cellular macromolecule metabolic process GO:0044260 391 0.065
sleep GO:0030431 1 0.065
organic acid metabolic process GO:0006082 31 0.063
generation of neurons GO:0048699 385 0.062
phagocytosis engulfment GO:0006911 1 0.061
immune system process GO:0002376 241 0.060
Human
organism emergence from protective structure GO:0071684 4 0.059
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.057
heart development GO:0007507 313 0.056
response to chemical GO:0042221 320 0.055
single organism organelle organization GO:1902589 199 0.055
carboxylic acid metabolic process GO:0019752 22 0.055
negative regulation of cellular process GO:0048523 283 0.053
oxoacid metabolic process GO:0043436 31 0.052
response to monosaccharide GO:0034284 3 0.049
cellular response to chemical stimulus GO:0070887 157 0.047
angiogenesis GO:0001525 158 0.047
Zebrafish
membrane invagination GO:0010324 1 0.047
interspecies interaction between organisms GO:0044419 4 0.047
oxidation reduction process GO:0055114 41 0.046
response to endogenous stimulus GO:0009719 83 0.046
cellular amide metabolic process GO:0043603 4 0.046
fatty acid oxidation GO:0019395 1 0.045
cellular lipid catabolic process GO:0044242 3 0.044
positive regulation of cell activation GO:0050867 1 0.043
small molecule catabolic process GO:0044282 3 0.043
cell substrate adhesion GO:0031589 4 0.043
liver development GO:0001889 96 0.042
spermatid differentiation GO:0048515 2 0.042
regulation of hormone secretion GO:0046883 2 0.041
secondary metabolic process GO:0019748 3 0.041
regulation of cell activation GO:0050865 1 0.041
regulation of autophagy GO:0010506 3 0.041
system process GO:0003008 185 0.041
response to ketone GO:1901654 1 0.041
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.040
chordate embryonic development GO:0043009 271 0.040
skin development GO:0043588 54 0.039
lipid catabolic process GO:0016042 4 0.039
positive regulation of secretion GO:0051047 1 0.039
developmental growth GO:0048589 166 0.038
carbohydrate homeostasis GO:0033500 1 0.037
blood vessel morphogenesis GO:0048514 216 0.037
Zebrafish
positive regulation of cell adhesion GO:0045785 1 0.036
positive regulation of biological process GO:0048518 253 0.035
Human
phagocytosis GO:0006909 3 0.035
regulation of protein complex assembly GO:0043254 3 0.035
circadian sleep wake cycle GO:0042745 2 0.035
regulation of protein import into nucleus GO:0042306 2 0.035
cellular response to external stimulus GO:0071496 2 0.034
regulation of wound healing GO:0061041 2 0.034
hatching GO:0035188 4 0.034
response to glucose GO:0009749 3 0.034
intracellular receptor signaling pathway GO:0030522 30 0.034
cell matrix adhesion GO:0007160 4 0.034
pancreas development GO:0031016 84 0.033
neuron projection morphogenesis GO:0048812 161 0.032
multicellular organism growth GO:0035264 4 0.031
stem cell proliferation GO:0072089 4 0.031
leukocyte proliferation GO:0070661 1 0.031
hormone secretion GO:0046879 2 0.031
mycotoxin metabolic process GO:0043385 1 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
regulation of biological quality GO:0065008 263 0.030
Zebrafish
pyruvate metabolic process GO:0006090 1 0.030
positive regulation of secretion by cell GO:1903532 1 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
ether metabolic process GO:0018904 1 0.030
protein import GO:0017038 3 0.030
protein localization to nucleus GO:0034504 3 0.030
circadian sleep wake cycle process GO:0022410 2 0.030
signal transduction GO:0007165 455 0.030
enzyme linked receptor protein signaling pathway GO:0007167 106 0.029
homeostatic process GO:0042592 142 0.029
regulation of localization GO:0032879 104 0.029
regulation of stem cell proliferation GO:0072091 2 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
positive regulation of catabolic process GO:0009896 4 0.029
response to external biotic stimulus GO:0043207 97 0.028
neuroblast proliferation GO:0007405 2 0.027
organic substance biosynthetic process GO:1901576 289 0.027
spermatid development GO:0007286 2 0.026
circadian sleep wake cycle sleep GO:0050802 1 0.026
regulation of tube size GO:0035150 2 0.026
regulation of cytokine production GO:0001817 3 0.026
cellular ketone metabolic process GO:0042180 11 0.026
regulation of protein localization to nucleus GO:1900180 2 0.026
regulation of multicellular organismal development GO:2000026 223 0.025
cell projection morphogenesis GO:0048858 244 0.025
lipid oxidation GO:0034440 1 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
cell part morphogenesis GO:0032990 246 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
muscle tissue development GO:0060537 110 0.025
regulation of blood vessel size GO:0050880 2 0.025
protein activation cascade GO:0072376 6 0.024
Human Zebrafish
regulation of cell death GO:0010941 103 0.024
striated muscle tissue development GO:0014706 110 0.024
regulation of cell development GO:0060284 100 0.024
cell morphogenesis GO:0000902 289 0.024
regulation of circadian rhythm GO:0042752 4 0.023
catabolic process GO:0009056 32 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
periodic partitioning GO:0007365 1 0.023
blood circulation GO:0008015 87 0.023
photoreceptor cell differentiation GO:0046530 55 0.023
cellular component biogenesis GO:0044085 178 0.023
aflatoxin metabolic process GO:0046222 1 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
muscle structure development GO:0061061 196 0.023
amine metabolic process GO:0009308 2 0.023
response to other organism GO:0051707 97 0.022
response to organic cyclic compound GO:0014070 51 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
anion transport GO:0006820 38 0.022
cellular component assembly GO:0022607 170 0.022
regulation of metabolic process GO:0019222 359 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
regulation of cell substrate adhesion GO:0010810 1 0.022
synaptic target recognition GO:0008039 1 0.022
cellular response to growth factor stimulus GO:0071363 39 0.021
response to nitrogen compound GO:1901698 19 0.021
protein import into nucleus GO:0006606 3 0.021
response to drug GO:0042493 3 0.021
cellular amine metabolic process GO:0044106 2 0.021
regulation of metal ion transport GO:0010959 4 0.021
neuron differentiation GO:0030182 353 0.021
positive regulation of cell cycle GO:0045787 3 0.021
cellular aldehyde metabolic process GO:0006081 4 0.021
lymphocyte proliferation GO:0046651 1 0.021
cellular component movement GO:0006928 335 0.021
long chain fatty acid transport GO:0015909 1 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
coagulation GO:0050817 13 0.020
Zebrafish
hepaticobiliary system development GO:0061008 98 0.020
response to organic substance GO:0010033 153 0.020
gland development GO:0048732 143 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
monoamine transport GO:0015844 1 0.019
cell cell recognition GO:0009988 1 0.019
regulation of dendrite development GO:0050773 3 0.019
programmed cell death GO:0012501 119 0.019
neuron projection development GO:0031175 180 0.019
cell projection organization GO:0030030 284 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
cellular response to organic substance GO:0071310 105 0.019
regulation of cellular component organization GO:0051128 86 0.019
b cell activation GO:0042113 2 0.019
production of molecular mediator of immune response GO:0002440 2 0.019
positive regulation of leukocyte differentiation GO:1902107 1 0.019
regulation of developmental process GO:0050793 247 0.019
gastrulation GO:0007369 208 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
positive regulation of cell killing GO:0031343 2 0.018
regulation of sodium ion transport GO:0002028 2 0.018
biosynthetic process GO:0009058 294 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
response to amine GO:0014075 1 0.018
neuron remodeling GO:0016322 1 0.018
regulation of neurogenesis GO:0050767 87 0.018
peptide transport GO:0015833 1 0.018
leukocyte mediated cytotoxicity GO:0001909 1 0.018
protein metabolic process GO:0019538 183 0.018
Human Zebrafish
regulation of circadian sleep wake cycle GO:0042749 1 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
positive regulation of cellular process GO:0048522 201 0.017
regulation of cell differentiation GO:0045595 142 0.017
protein targeting to nucleus GO:0044744 3 0.017
glucose homeostasis GO:0042593 1 0.017
response to amphetamine GO:0001975 1 0.017
cellular protein catabolic process GO:0044257 4 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
gtp catabolic process GO:0006184 2 0.017
organic substance catabolic process GO:1901575 28 0.017
meiotic chromosome segregation GO:0045132 3 0.017
cellular response to nutrient levels GO:0031669 2 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
protein modification process GO:0036211 100 0.016
amino acid transport GO:0006865 2 0.016
cell migration GO:0016477 237 0.016
cellular response to starvation GO:0009267 1 0.016
response to hormone GO:0009725 48 0.016
regulation of immune system process GO:0002682 34 0.016
Human
response to biotic stimulus GO:0009607 97 0.016
transport GO:0006810 220 0.016
embryonic hemopoiesis GO:0035162 53 0.016
negative regulation of biological process GO:0048519 304 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of protein targeting GO:1903533 2 0.015
nuclear import GO:0051170 3 0.015
regulation of gtpase activity GO:0043087 2 0.015
regulation of natural killer cell mediated immunity GO:0002715 1 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
regeneration GO:0031099 91 0.015
taxis GO:0042330 109 0.015
fatty acid catabolic process GO:0009062 1 0.015
cellular respiration GO:0045333 3 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
small molecule metabolic process GO:0044281 77 0.015
acylglycerol homeostasis GO:0055090 2 0.015
chemotaxis GO:0006935 104 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
single organism transport GO:0044765 206 0.015
muscle cell migration GO:0014812 4 0.015
cellular lipid metabolic process GO:0044255 36 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
brain development GO:0007420 293 0.015
chemical homeostasis GO:0048878 49 0.015
organelle assembly GO:0070925 110 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of dna replication GO:0006275 3 0.015
response to stress GO:0006950 263 0.015
Human Zebrafish
cardiac muscle tissue development GO:0048738 48 0.014
nuclear transport GO:0051169 4 0.014
aorta development GO:0035904 4 0.014
tube morphogenesis GO:0035239 349 0.014
positive regulation of exocytosis GO:0045921 1 0.014
intracellular signal transduction GO:0035556 85 0.014
heart morphogenesis GO:0003007 156 0.014
cardiocyte differentiation GO:0035051 44 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
embryonic pattern specification GO:0009880 44 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
regulation of reproductive process GO:2000241 4 0.014
tissue regeneration GO:0042246 74 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
homeostasis of number of cells GO:0048872 62 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
fat soluble vitamin metabolic process GO:0006775 4 0.013
digestive tract development GO:0048565 265 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
embryonic organ development GO:0048568 381 0.013
cell killing GO:0001906 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
stem cell development GO:0048864 82 0.013
meiotic cell cycle process GO:1903046 3 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
outflow tract morphogenesis GO:0003151 1 0.013
regulation of apoptotic process GO:0042981 98 0.013
regulation of cellular response to growth factor stimulus GO:0090287 35 0.013
female meiotic division GO:0007143 2 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
ear development GO:0043583 127 0.013
response to nutrient GO:0007584 3 0.013
vitamin a metabolic process GO:0006776 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
muscle organ development GO:0007517 101 0.013
peptidyl serine modification GO:0018209 2 0.013
regulation of hydrolase activity GO:0051336 28 0.013
positive regulation of immune effector process GO:0002699 3 0.013
epithelial cell differentiation GO:0030855 116 0.013
epidermis development GO:0008544 48 0.013
lipid metabolic process GO:0006629 52 0.013
neuromast development GO:0048884 46 0.012
muscle cell development GO:0055001 115 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
dopamine metabolic process GO:0042417 2 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
death GO:0016265 121 0.012
foregut morphogenesis GO:0007440 4 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
post embryonic organ development GO:0048569 4 0.012
negative regulation of multi organism process GO:0043901 3 0.012
carboxylic acid transport GO:0046942 8 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
response to vitamin GO:0033273 3 0.012
response to inorganic substance GO:0010035 38 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
response to metal ion GO:0010038 34 0.012
cytoskeleton organization GO:0007010 96 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
toxin metabolic process GO:0009404 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
single organism localization GO:1902578 225 0.011
microtubule organizing center organization GO:0031023 1 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
rna metabolic process GO:0016070 219 0.011
axon development GO:0061564 166 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
single organism nuclear import GO:1902593 3 0.011
circadian rhythm GO:0007623 19 0.011
positive regulation of cytokine production GO:0001819 2 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
multicellular organismal response to stress GO:0033555 2 0.011
stem cell differentiation GO:0048863 117 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
locomotion GO:0040011 313 0.011
regulation of natural killer cell mediated cytotoxicity GO:0042269 1 0.011
camera type eye development GO:0043010 222 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
positive regulation of carbohydrate metabolic process GO:0045913 1 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
stem cell division GO:0017145 1 0.011
cell cycle GO:0007049 93 0.010
glial cell proliferation GO:0014009 4 0.010
localization of cell GO:0051674 244 0.010
sensory organ development GO:0007423 393 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
circulatory system process GO:0003013 87 0.010
regulation of molecular function GO:0065009 70 0.010
phosphorylation GO:0016310 69 0.010
lateral line system development GO:0048925 76 0.010
cytokinesis GO:0000910 3 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
macromolecule localization GO:0033036 54 0.010
somatic muscle development GO:0007525 4 0.010
regulation of cellular metabolic process GO:0031323 320 0.010
response to oxygen containing compound GO:1901700 55 0.010
protein stabilization GO:0050821 2 0.010
cellular biosynthetic process GO:0044249 286 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
glycoprotein metabolic process GO:0009100 23 0.010
striated muscle cell differentiation GO:0051146 129 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
neurotransmitter secretion GO:0007269 2 0.010

angptl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
disease of metabolism DOID:0014667 0 0.036
acquired metabolic disease DOID:0060158 0 0.011
immune system disease DOID:2914 0 0.010