Danio rerio

0 known processes

ap1s2

adaptor-related protein complex 1, sigma 2 subunit

(Aliases: wu:fb94g06,wu:fd19a08,zgc:77925,zgc:65824)

ap1s2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transport GO:0051050 2 0.207
cellular aromatic compound metabolic process GO:0006725 295 0.206
ribonucleoside monophosphate catabolic process GO:0009158 4 0.171
biosynthetic process GO:0009058 294 0.129
purine nucleoside monophosphate catabolic process GO:0009128 4 0.113
dna templated transcription initiation GO:0006352 1 0.110
nucleoside monophosphate catabolic process GO:0009125 4 0.106
regulation of establishment of protein localization GO:0070201 4 0.099
aromatic compound biosynthetic process GO:0019438 217 0.097
establishment of localization GO:0051234 244 0.096
cellular biosynthetic process GO:0044249 286 0.096
cellular component movement GO:0006928 335 0.095
larval development GO:0002164 2 0.088
Worm
cytokinesis GO:0000910 3 0.086
cytoskeleton dependent cytokinesis GO:0061640 3 0.083
central nervous system development GO:0007417 387 0.083
single organism localization GO:1902578 225 0.080
small molecule metabolic process GO:0044281 77 0.078
single organism transport GO:0044765 206 0.077
system process GO:0003008 185 0.076
regulation of protein transport GO:0051223 3 0.075
microtubule based process GO:0007017 60 0.073
organic cyclic compound metabolic process GO:1901360 301 0.073
positive regulation of cellular process GO:0048522 201 0.072
cellular macromolecule metabolic process GO:0044260 391 0.071
nucleobase containing compound biosynthetic process GO:0034654 205 0.070
atp catabolic process GO:0006200 4 0.070
cortical cytoskeleton organization GO:0030865 1 0.067
nuclear transport GO:0051169 4 0.067
regulation of biological quality GO:0065008 263 0.067
mitochondrion organization GO:0007005 4 0.066
nitrogen compound metabolic process GO:0006807 319 0.066
nuclear migration GO:0007097 3 0.063
cellular macromolecule biosynthetic process GO:0034645 224 0.063
cell projection organization GO:0030030 284 0.063
heterocycle metabolic process GO:0046483 290 0.060
cellular nitrogen compound metabolic process GO:0034641 290 0.058
actin filament based process GO:0030029 64 0.057
response to hexose GO:0009746 3 0.056
gene expression GO:0010467 252 0.055
organic substance biosynthetic process GO:1901576 289 0.055
macromolecule biosynthetic process GO:0009059 227 0.055
single organism membrane fusion GO:0044801 2 0.055
cellular component morphogenesis GO:0032989 336 0.053
organelle organization GO:0006996 227 0.052
positive regulation of cellular component biogenesis GO:0044089 3 0.052
autophagy GO:0006914 4 0.051
transcription dna templated GO:0006351 181 0.049
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.049
head development GO:0060322 303 0.049
response to chemical GO:0042221 320 0.047
transport GO:0006810 220 0.047
cell morphogenesis GO:0000902 289 0.047
negative regulation of protein transport GO:0051224 3 0.047
nucleic acid templated transcription GO:0097659 181 0.046
aging GO:0007568 2 0.045
mitotic cytokinesis GO:0000281 3 0.045
cellular component biogenesis GO:0044085 178 0.045
organonitrogen compound metabolic process GO:1901564 74 0.045
response to stress GO:0006950 263 0.045
regulation of cell shape GO:0008360 1 0.045
regulation of signaling GO:0023051 235 0.044
exocytosis GO:0006887 1 0.044
regulation of organelle organization GO:0033043 29 0.044
localization of cell GO:0051674 244 0.043
signal transduction GO:0007165 455 0.043
single organism nuclear import GO:1902593 3 0.043
neuron differentiation GO:0030182 353 0.041
mitotic cell cycle process GO:1903047 48 0.041
amine metabolic process GO:0009308 2 0.040
immune system process GO:0002376 241 0.040
cortical actin cytoskeleton organization GO:0030866 1 0.040
nucleocytoplasmic transport GO:0006913 4 0.040
organic acid metabolic process GO:0006082 31 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.039
cellular ketone metabolic process GO:0042180 11 0.039
establishment of localization in cell GO:0051649 77 0.039
blood vessel development GO:0001568 246 0.039
positive regulation of secretion by cell GO:1903532 1 0.039
cellular component assembly GO:0022607 170 0.038
nucleobase containing compound metabolic process GO:0006139 274 0.037
generation of neurons GO:0048699 385 0.037
vasculature development GO:0001944 278 0.037
cell migration GO:0016477 237 0.037
maintenance of location GO:0051235 4 0.036
protein metabolic process GO:0019538 183 0.036
cell projection morphogenesis GO:0048858 244 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.036
phagocytosis GO:0006909 3 0.035
positive regulation of secretion GO:0051047 1 0.035
protein import into nucleus GO:0006606 3 0.034
negative regulation of cytoplasmic transport GO:1903650 2 0.034
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
neuron development GO:0048666 262 0.034
regulation of gene expression GO:0010468 265 0.034
actin cytoskeleton organization GO:0030036 63 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
meiotic cell cycle process GO:1903046 3 0.033
regulation of multicellular organismal process GO:0051239 277 0.033
response to monosaccharide GO:0034284 3 0.033
determination of bilateral symmetry GO:0009855 204 0.032
positive regulation of cytoskeleton organization GO:0051495 3 0.032
positive regulation of biological process GO:0048518 253 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
response to wounding GO:0009611 116 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
regulation of cellular metabolic process GO:0031323 320 0.032
protein polymerization GO:0051258 4 0.032
negative regulation of metabolic process GO:0009892 86 0.032
protein import GO:0017038 3 0.032
cell part morphogenesis GO:0032990 246 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.031
cellular amine metabolic process GO:0044106 2 0.031
cell cycle GO:0007049 93 0.031
neurological system process GO:0050877 62 0.031
protein localization to plasma membrane GO:0072659 1 0.031
membrane fusion GO:0061025 2 0.030
positive regulation of protein polymerization GO:0032273 2 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.029
cellular response to oxygen levels GO:0071453 1 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
regulation of intracellular protein transport GO:0033157 3 0.028
specification of symmetry GO:0009799 204 0.028
neuron projection morphogenesis GO:0048812 161 0.028
positive regulation of wound healing GO:0090303 1 0.028
establishment of protein localization to plasma membrane GO:0090002 1 0.028
neuron projection development GO:0031175 180 0.027
multi organism process GO:0051704 134 0.026
actin filament polymerization GO:0030041 2 0.026
regulation of cellular component organization GO:0051128 86 0.026
negative regulation of intracellular transport GO:0032387 3 0.026
immune system development GO:0002520 191 0.026
programmed cell death GO:0012501 119 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
protein localization to nucleus GO:0034504 3 0.026
cellular protein metabolic process GO:0044267 129 0.026
macromolecule modification GO:0043412 111 0.026
carbohydrate derivative metabolic process GO:1901135 61 0.025
germ line stem cell maintenance GO:0030718 2 0.025
nuclear import GO:0051170 3 0.025
cellular localization GO:0051641 97 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
actin polymerization or depolymerization GO:0008154 2 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
cell proliferation GO:0008283 80 0.024
cilium morphogenesis GO:0060271 85 0.024
carbohydrate homeostasis GO:0033500 1 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
heart development GO:0007507 313 0.023
regulation of localization GO:0032879 104 0.023
muscle tissue development GO:0060537 110 0.023
actin filament based movement GO:0030048 1 0.022
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
regulation of rna metabolic process GO:0051252 224 0.022
cytoskeleton organization GO:0007010 96 0.022
death GO:0016265 121 0.021
gtp metabolic process GO:0046039 4 0.021
cell substrate adhesion GO:0031589 4 0.021
brain development GO:0007420 293 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
rna biosynthetic process GO:0032774 181 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
response to organic substance GO:0010033 153 0.021
protein modification process GO:0036211 100 0.021
ameboidal type cell migration GO:0001667 143 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
Worm
secondary metabolic process GO:0019748 3 0.020
regulation of protein complex assembly GO:0043254 3 0.020
cell motility GO:0048870 244 0.020
regulation of developmental process GO:0050793 247 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
regulation of binding GO:0051098 3 0.020
regulation of mitochondrion organization GO:0010821 1 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
response to glucose GO:0009749 3 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
mitotic cell cycle GO:0000278 64 0.019
ribose phosphate metabolic process GO:0019693 27 0.019
oxoacid metabolic process GO:0043436 31 0.019
regulation of metabolic process GO:0019222 359 0.019
peptidyl lysine trimethylation GO:0018023 1 0.019
angiogenesis GO:0001525 158 0.019
multicellular organism growth GO:0035264 4 0.019
positive regulation of cell cycle GO:0045787 3 0.018
positive regulation of catabolic process GO:0009896 4 0.018
retina development in camera type eye GO:0060041 146 0.018
regulation of biosynthetic process GO:0009889 250 0.018
regulation of systemic arterial blood pressure GO:0003073 1 0.018
intracellular signal transduction GO:0035556 85 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
cilium organization GO:0044782 71 0.018
positive regulation of histone modification GO:0031058 1 0.018
eye development GO:0001654 277 0.017
regulation of response to stimulus GO:0048583 269 0.017
small gtpase mediated signal transduction GO:0007264 8 0.017
determination of left right symmetry GO:0007368 179 0.017
cellular response to external stimulus GO:0071496 2 0.017
spermatid differentiation GO:0048515 2 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
cation transport GO:0006812 81 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of cell differentiation GO:0045595 142 0.016
meiotic nuclear division GO:0007126 4 0.016
wound healing GO:0042060 90 0.016
regulation of protein targeting GO:1903533 2 0.016
homeostasis of number of cells GO:0048872 62 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
nucleic acid metabolic process GO:0090304 244 0.016
cognition GO:0050890 1 0.016
locomotion GO:0040011 313 0.016
Worm
blood vessel morphogenesis GO:0048514 216 0.016
regulation of transcription dna templated GO:0006355 213 0.016
protein complex subunit organization GO:0071822 46 0.016
spermatid development GO:0007286 2 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
single organism organelle organization GO:1902589 199 0.016
protein acylation GO:0043543 3 0.016
gland development GO:0048732 143 0.016
regulation of cell communication GO:0010646 232 0.015
regulation of exocytosis GO:0017157 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
taxis GO:0042330 109 0.015
regulation of signal transduction GO:0009966 225 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
regulation of protein polymerization GO:0032271 2 0.015
hatching GO:0035188 4 0.015
striated muscle tissue development GO:0014706 110 0.015
chordate embryonic development GO:0043009 271 0.015
regulation of transport GO:0051049 45 0.015
adherens junction organization GO:0034332 4 0.015
regulation of autophagy GO:0010506 3 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.014
gtp catabolic process GO:0006184 2 0.014
organism emergence from protective structure GO:0071684 4 0.014
regulation of primary metabolic process GO:0080090 311 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
axonogenesis GO:0007409 152 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
mononuclear cell proliferation GO:0032943 1 0.014
cell projection assembly GO:0030031 64 0.014
mechanosensory behavior GO:0007638 2 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
stem cell proliferation GO:0072089 4 0.014
muscle structure development GO:0061061 196 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
neuroblast proliferation GO:0007405 2 0.014
endosomal transport GO:0016197 2 0.014
hemopoiesis GO:0030097 183 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
cell death GO:0008219 121 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
regionalization GO:0003002 274 0.013
circulatory system process GO:0003013 87 0.013
response to drug GO:0042493 3 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
phosphorylation GO:0016310 69 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
organophosphate metabolic process GO:0019637 37 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
eye morphogenesis GO:0048592 144 0.013
axon development GO:0061564 166 0.013
signal transduction in absence of ligand GO:0038034 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
actin mediated cell contraction GO:0070252 1 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
nucleic acid transport GO:0050657 2 0.013
rna metabolic process GO:0016070 219 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
organelle localization GO:0051640 49 0.013
striated muscle cell development GO:0055002 108 0.013
female sex differentiation GO:0046660 4 0.013
neurotransmitter transport GO:0006836 2 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of blood pressure GO:0008217 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of apoptotic process GO:0042981 98 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
response to abiotic stimulus GO:0009628 122 0.012
sensory organ morphogenesis GO:0090596 200 0.012
cell cycle process GO:0022402 53 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
response to nutrient GO:0007584 3 0.012
regulation of protein metabolic process GO:0051246 56 0.012
neurotransmitter secretion GO:0007269 2 0.012
digestive tract morphogenesis GO:0048546 231 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
melanin metabolic process GO:0006582 2 0.012
regulation of cytoskeleton organization GO:0051493 11 0.012
hormone transport GO:0009914 2 0.012
single organism metabolic process GO:0044710 217 0.012
cellular protein localization GO:0034613 20 0.012
photoreceptor cell outer segment organization GO:0035845 9 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
camera type eye development GO:0043010 222 0.012
axis specification GO:0009798 43 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
hormone secretion GO:0046879 2 0.011
cranial nerve development GO:0021545 42 0.011
single fertilization GO:0007338 3 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
ribonucleoside metabolic process GO:0009119 11 0.011
cell junction maintenance GO:0034331 2 0.011
blood circulation GO:0008015 87 0.011
sensory organ development GO:0007423 393 0.011
cytokinetic process GO:0032506 2 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
cellular protein complex assembly GO:0043623 19 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
rna transport GO:0050658 2 0.011
protein secretion GO:0009306 1 0.011
actin filament organization GO:0007015 15 0.011
negative regulation of chromatin modification GO:1903309 1 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.011
recombinational repair GO:0000725 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
hindbrain development GO:0030902 91 0.011
skeletal muscle tissue development GO:0007519 67 0.011
neuron projection guidance GO:0097485 86 0.011
peptidyl serine modification GO:0018209 2 0.010
negative regulation of biological process GO:0048519 304 0.010
lipid storage GO:0019915 1 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
cell cycle arrest GO:0007050 1 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
peptidyl lysine dimethylation GO:0018027 1 0.010
lymphocyte proliferation GO:0046651 1 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
ion transport GO:0006811 114 0.010
erythrocyte homeostasis GO:0034101 55 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
fertilization GO:0009566 3 0.010

ap1s2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.019
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.010
disease of cellular proliferation DOID:14566 0 0.010