Danio rerio

0 known processes

appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

appl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.360
cellular macromolecule metabolic process GO:0044260 391 0.332
cell morphogenesis GO:0000902 289 0.310
regulation of primary metabolic process GO:0080090 311 0.307
morphogenesis of an epithelium GO:0002009 333 0.270
rna metabolic process GO:0016070 219 0.267
generation of neurons GO:0048699 385 0.261
regulation of metabolic process GO:0019222 359 0.259
cell surface receptor signaling pathway GO:0007166 325 0.250
regulation of gene expression GO:0010468 265 0.248
cellular component morphogenesis GO:0032989 336 0.238
digestive system development GO:0055123 289 0.226
digestive tract development GO:0048565 265 0.226
neuroblast proliferation GO:0007405 2 0.225
tube morphogenesis GO:0035239 349 0.218
cell part morphogenesis GO:0032990 246 0.215
regulation of nitrogen compound metabolic process GO:0051171 251 0.214
cell projection organization GO:0030030 284 0.210
regulation of macromolecule metabolic process GO:0060255 317 0.209
embryonic heart tube development GO:0035050 133 0.200
heart development GO:0007507 313 0.196
embryo development ending in birth or egg hatching GO:0009792 271 0.194
gastrulation GO:0007369 208 0.194
enzyme linked receptor protein signaling pathway GO:0007167 106 0.193
cellular component movement GO:0006928 335 0.188
regulation of cellular metabolic process GO:0031323 320 0.187
regulation of epithelial cell proliferation GO:0050678 3 0.187
regulation of macromolecule biosynthetic process GO:0010556 225 0.185
regulation of rna metabolic process GO:0051252 224 0.180
cell projection morphogenesis GO:0048858 244 0.178
regulation of synapse organization GO:0050807 3 0.178
central nervous system development GO:0007417 387 0.174
heterocycle metabolic process GO:0046483 290 0.171
cellular macromolecule biosynthetic process GO:0034645 224 0.167
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.164
nucleic acid metabolic process GO:0090304 244 0.158
organic cyclic compound metabolic process GO:1901360 301 0.158
cellular nitrogen compound biosynthetic process GO:0044271 218 0.149
locomotion GO:0040011 313 0.147
stem cell proliferation GO:0072089 4 0.146
cell morphogenesis involved in differentiation GO:0000904 195 0.146
negative regulation of biological process GO:0048519 304 0.145
cellular aromatic compound metabolic process GO:0006725 295 0.142
eye development GO:0001654 277 0.142
response to chemical GO:0042221 320 0.137
nucleobase containing compound metabolic process GO:0006139 274 0.135
aromatic compound biosynthetic process GO:0019438 217 0.133
cell fate commitment GO:0045165 99 0.130
regulation of rna biosynthetic process GO:2001141 213 0.129
specification of symmetry GO:0009799 204 0.126
neuron differentiation GO:0030182 353 0.126
gene expression GO:0010467 252 0.122
embryonic organ development GO:0048568 381 0.121
cellular nitrogen compound metabolic process GO:0034641 290 0.121
heterocycle biosynthetic process GO:0018130 215 0.118
sprouting angiogenesis GO:0002040 53 0.118
larval development GO:0002164 2 0.117
digestive tract morphogenesis GO:0048546 231 0.117
reflex GO:0060004 2 0.114
localization of cell GO:0051674 244 0.112
positive regulation of biological process GO:0048518 253 0.112
nitrogen compound metabolic process GO:0006807 319 0.110
neuron projection morphogenesis GO:0048812 161 0.110
response to external stimulus GO:0009605 264 0.110
embryonic heart tube morphogenesis GO:0003143 108 0.109
regulation of cellular biosynthetic process GO:0031326 245 0.108
regulation of biosynthetic process GO:0009889 250 0.108
phagocytosis GO:0006909 3 0.107
positive regulation of cellular process GO:0048522 201 0.106
nucleic acid templated transcription GO:0097659 181 0.104
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.104
guanosine containing compound metabolic process GO:1901068 4 0.103
organelle organization GO:0006996 227 0.102
heart morphogenesis GO:0003007 156 0.102
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.099
determination of left right symmetry GO:0007368 179 0.098
axon development GO:0061564 166 0.097
cognition GO:0050890 1 0.097
regulation of nucleic acid templated transcription GO:1903506 213 0.096
protein metabolic process GO:0019538 183 0.095
macromolecule biosynthetic process GO:0009059 227 0.095
regulation of cell shape GO:0008360 1 0.093
regulation of signal transduction GO:0009966 225 0.092
neuron projection development GO:0031175 180 0.092
cell motility GO:0048870 244 0.090
axonogenesis GO:0007409 152 0.090
brain development GO:0007420 293 0.089
single organism organelle organization GO:1902589 199 0.087
rna biosynthetic process GO:0032774 181 0.084
organic substance biosynthetic process GO:1901576 289 0.083
heart looping GO:0001947 94 0.082
regulation of signaling GO:0023051 235 0.080
exocytosis GO:0006887 1 0.080
establishment of cell polarity GO:0030010 18 0.080
neuron development GO:0048666 262 0.078
phosphorus metabolic process GO:0006793 109 0.077
protein modification process GO:0036211 100 0.075
organelle localization GO:0051640 49 0.072
regulation of protein transport GO:0051223 3 0.072
detection of mechanical stimulus involved in sensory perception of touch GO:0050976 2 0.072
gtp metabolic process GO:0046039 4 0.072
cytoskeleton organization GO:0007010 96 0.071
bmp signaling pathway GO:0030509 52 0.071
regulation of response to stimulus GO:0048583 269 0.070
biosynthetic process GO:0009058 294 0.069
protein secretion GO:0009306 1 0.067
negative regulation of cellular process GO:0048523 283 0.065
chemotaxis GO:0006935 104 0.065
cilium assembly GO:0042384 58 0.065
actin polymerization or depolymerization GO:0008154 2 0.064
taxis GO:0042330 109 0.064
sensory organ development GO:0007423 393 0.064
regulation of nervous system development GO:0051960 90 0.062
synaptic growth at neuromuscular junction GO:0051124 2 0.062
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.062
detection of external stimulus GO:0009581 24 0.062
head development GO:0060322 303 0.061
regulation of protein localization to nucleus GO:1900180 2 0.061
regulation of developmental process GO:0050793 247 0.060
stem cell development GO:0048864 82 0.060
establishment of localization GO:0051234 244 0.060
negative regulation of gene expression GO:0010629 65 0.060
blood vessel development GO:0001568 246 0.060
regulation of canonical wnt signaling pathway GO:0060828 34 0.059
regulation of synapse assembly GO:0051963 3 0.059
establishment of protein localization to organelle GO:0072594 4 0.058
nucleobase containing compound biosynthetic process GO:0034654 205 0.058
regulation of cell communication GO:0010646 232 0.057
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.057
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.057
positive regulation of epithelial cell proliferation GO:0050679 1 0.056
regionalization GO:0003002 274 0.056
microtubule cytoskeleton organization GO:0000226 33 0.056
somite development GO:0061053 96 0.056
organic cyclic compound biosynthetic process GO:1901362 223 0.055
negative regulation of cell communication GO:0010648 96 0.055
response to organic substance GO:0010033 153 0.055
protein targeting to nucleus GO:0044744 3 0.055
guanosine containing compound catabolic process GO:1901069 2 0.054
regulation of multicellular organismal development GO:2000026 223 0.054
stem cell maintenance GO:0019827 4 0.054
regulation of neural precursor cell proliferation GO:2000177 3 0.053
muscle structure development GO:0061061 196 0.053
positive regulation of cell cycle GO:0045787 3 0.053
transcription from rna polymerase ii promoter GO:0006366 80 0.052
protein import into nucleus GO:0006606 3 0.052
determination of bilateral symmetry GO:0009855 204 0.052
neurological system process GO:0050877 62 0.051
regulation of establishment of protein localization GO:0070201 4 0.050
regulation of biological quality GO:0065008 263 0.049
sensory perception of touch GO:0050975 2 0.049
positive regulation of transport GO:0051050 2 0.048
cilium morphogenesis GO:0060271 85 0.048
canonical wnt signaling pathway GO:0060070 48 0.048
formation of primary germ layer GO:0001704 62 0.048
chemosensory behavior GO:0007635 1 0.048
retina development in camera type eye GO:0060041 146 0.048
positive regulation of striated muscle cell differentiation GO:0051155 1 0.047
protein localization to nucleus GO:0034504 3 0.047
cellular protein modification process GO:0006464 100 0.047
single fertilization GO:0007338 3 0.046
gtp catabolic process GO:0006184 2 0.046
nuclear transport GO:0051169 4 0.046
startle response GO:0001964 4 0.045
regulation of transcription dna templated GO:0006355 213 0.045
striated muscle cell differentiation GO:0051146 129 0.045
regulation of phosphorus metabolic process GO:0051174 43 0.045
epidermal cell fate specification GO:0009957 4 0.044
aging GO:0007568 2 0.044
ameboidal type cell migration GO:0001667 143 0.043
spermatid development GO:0007286 2 0.043
sensory perception of mechanical stimulus GO:0050954 16 0.043
primary neural tube formation GO:0014020 1 0.043
meiotic nuclear division GO:0007126 4 0.043
determination of heart left right asymmetry GO:0061371 117 0.042
macromolecule modification GO:0043412 111 0.042
fertilization GO:0009566 3 0.041
regulation of cardiac muscle tissue development GO:0055024 1 0.041
single organism localization GO:1902578 225 0.041
somatic stem cell maintenance GO:0035019 1 0.041
nucleocytoplasmic transport GO:0006913 4 0.041
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.041
axon guidance GO:0007411 86 0.041
regulation of bmp signaling pathway GO:0030510 39 0.040
regulation of stem cell differentiation GO:2000736 4 0.040
cellular protein metabolic process GO:0044267 129 0.040
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.039
negative regulation of response to stimulus GO:0048585 104 0.039
compound eye development GO:0048749 2 0.039
negative regulation of signaling GO:0023057 96 0.039
muscle cell differentiation GO:0042692 139 0.039
tissue migration GO:0090130 37 0.039
gland development GO:0048732 143 0.039
regulation of dna replication GO:0006275 3 0.038
immune system process GO:0002376 241 0.038
nuclear import GO:0051170 3 0.038
microtubule based process GO:0007017 60 0.037
muscle tissue development GO:0060537 110 0.037
protein import GO:0017038 3 0.037
cellular biosynthetic process GO:0044249 286 0.036
post embryonic organ development GO:0048569 4 0.036
embryonic organ morphogenesis GO:0048562 274 0.036
cell fate specification GO:0001708 68 0.036
spindle assembly involved in mitosis GO:0090307 1 0.036
phosphate containing compound metabolic process GO:0006796 108 0.036
cellular ketone metabolic process GO:0042180 11 0.035
sensory perception GO:0007600 39 0.035
somatic muscle development GO:0007525 4 0.035
convergent extension GO:0060026 118 0.034
regulation of protein targeting GO:1903533 2 0.034
regulation of intracellular protein transport GO:0033157 3 0.034
regulation of neurogenesis GO:0050767 87 0.034
chordate embryonic development GO:0043009 271 0.034
regulation of nucleotide catabolic process GO:0030811 2 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.033
regulation of protein import into nucleus GO:0042306 2 0.033
cellular response to biotic stimulus GO:0071216 3 0.033
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
positive regulation of map kinase activity GO:0043406 3 0.032
oxoacid metabolic process GO:0043436 31 0.032
cellular localization GO:0051641 97 0.032
single organism transport GO:0044765 206 0.032
regulation of cell differentiation GO:0045595 142 0.032
transport GO:0006810 220 0.032
regulation of gtp catabolic process GO:0033124 2 0.032
hair cell differentiation GO:0035315 32 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
inner ear development GO:0048839 126 0.031
response to abiotic stimulus GO:0009628 122 0.031
stem cell division GO:0017145 1 0.031
angiogenesis GO:0001525 158 0.031
epidermis development GO:0008544 48 0.031
macromolecule localization GO:0033036 54 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
regulation of phosphate metabolic process GO:0019220 43 0.030
positive regulation of striated muscle tissue development GO:0045844 1 0.030
regulation of wound healing GO:0061041 2 0.030
organonitrogen compound metabolic process GO:1901564 74 0.029
somitogenesis GO:0001756 87 0.029
mesoderm morphogenesis GO:0048332 51 0.029
positive regulation of dna metabolic process GO:0051054 1 0.029
sensory perception of chemical stimulus GO:0007606 3 0.029
negative regulation of secretion GO:0051048 2 0.029
regulation of cysteine type endopeptidase activity GO:2000116 21 0.028
erk1 and erk2 cascade GO:0070371 4 0.028
neural crest formation GO:0014029 14 0.028
response to external biotic stimulus GO:0043207 97 0.028
negative regulation of wnt signaling pathway GO:0030178 30 0.028
membrane invagination GO:0010324 1 0.028
neural tube development GO:0021915 62 0.028
p38mapk cascade GO:0038066 1 0.028
response to carbohydrate GO:0009743 3 0.028
regulation of cellular component movement GO:0051270 55 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
ear development GO:0043583 127 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
cell migration GO:0016477 237 0.027
phagocytosis engulfment GO:0006911 1 0.027
mesoderm development GO:0007498 88 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
negative regulation of signal transduction GO:0009968 94 0.027
regulation of reactive oxygen species metabolic process GO:2000377 2 0.027
regulation of myotube differentiation GO:0010830 2 0.027
blood vessel morphogenesis GO:0048514 216 0.027
cellular response to organic substance GO:0071310 105 0.027
response to radiation GO:0009314 51 0.026
positive regulation of muscle cell differentiation GO:0051149 1 0.026
protein polymerization GO:0051258 4 0.026
developmental programmed cell death GO:0010623 4 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.026
amine metabolic process GO:0009308 2 0.026
wnt signaling pathway GO:0016055 80 0.026
positive regulation of macromolecule metabolic process GO:0010604 93 0.026
multicellular organism growth GO:0035264 4 0.026
positive regulation of metabolic process GO:0009893 108 0.026
striated muscle cell development GO:0055002 108 0.025
epithelium migration GO:0090132 25 0.025
mesenchyme development GO:0060485 127 0.025
positive regulation of secretion GO:0051047 1 0.025
kupffer s vesicle development GO:0070121 50 0.025
cell cycle process GO:0022402 53 0.025
regulation of erk1 and erk2 cascade GO:0070372 4 0.025
response to amino acid GO:0043200 2 0.025
actin filament polymerization GO:0030041 2 0.025
macromolecular complex disassembly GO:0032984 1 0.024
regulation of programmed cell death GO:0043067 101 0.024
regulation of rho protein signal transduction GO:0035023 2 0.024
cellular component disassembly GO:0022411 1 0.024
cellular component assembly GO:0022607 170 0.024
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
negative regulation of epithelial cell proliferation GO:0050680 1 0.024
lateral line system development GO:0048925 76 0.024
positive regulation of exocytosis GO:0045921 1 0.024
positive regulation of neuron apoptotic process GO:0043525 1 0.024
neurotransmitter transport GO:0006836 2 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
camera type eye development GO:0043010 222 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
neutrophil mediated immunity GO:0002446 1 0.023
positive regulation of gene expression GO:0010628 71 0.023
response to glucose GO:0009749 3 0.023
apoptotic process GO:0006915 116 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
leukocyte homeostasis GO:0001776 2 0.023
establishment of mitotic spindle orientation GO:0000132 10 0.023
small molecule metabolic process GO:0044281 77 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
exocrine system development GO:0035272 28 0.023
pronephros development GO:0048793 69 0.023
vasculature development GO:0001944 278 0.022
mesenchymal cell development GO:0014031 78 0.022
regulation of neutrophil migration GO:1902622 6 0.022
system process GO:0003008 185 0.022
negative regulation of protein localization to nucleus GO:1900181 2 0.022
spindle assembly GO:0051225 2 0.022
centrosome cycle GO:0007098 1 0.022
dorsal ventral pattern formation GO:0009953 125 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
convergent extension involved in gastrulation GO:0060027 71 0.022
establishment of localization in cell GO:0051649 77 0.022
cell proliferation involved in heart morphogenesis GO:0061323 2 0.022
cytokinesis GO:0000910 3 0.021
regulation of exocytosis GO:0017157 1 0.021
regulation of wnt signaling pathway GO:0030111 53 0.021
production of molecular mediator of immune response GO:0002440 2 0.021
actin cytoskeleton organization GO:0030036 63 0.021
metal ion homeostasis GO:0055065 26 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
cellular response to external stimulus GO:0071496 2 0.021
negative regulation of bmp signaling pathway GO:0030514 13 0.021
mesoderm formation GO:0001707 43 0.021
regulation of protein complex assembly GO:0043254 3 0.021
meiotic chromosome segregation GO:0045132 3 0.021
regulation of cytokine production GO:0001817 3 0.021
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.021
single organism nuclear import GO:1902593 3 0.020
cell projection assembly GO:0030031 64 0.020
spermatid differentiation GO:0048515 2 0.020
cellular amine metabolic process GO:0044106 2 0.020
cardiac muscle tissue development GO:0048738 48 0.020
keratinocyte differentiation GO:0030216 0 0.020
response to monosaccharide GO:0034284 3 0.020
endoderm development GO:0007492 49 0.020
membrane fusion GO:0061025 2 0.020
regulation of dendrite development GO:0050773 3 0.020
organic acid metabolic process GO:0006082 31 0.020
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.020
epithelial cell morphogenesis GO:0003382 2 0.019
transcription dna templated GO:0006351 181 0.019
organelle assembly GO:0070925 110 0.019
single organism metabolic process GO:0044710 217 0.019
peptidyl tyrosine dephosphorylation GO:0035335 1 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
fatty acid oxidation GO:0019395 1 0.019
nuclear migration GO:0007097 3 0.019
regulation of cardiac muscle cell differentiation GO:2000725 1 0.019
ventricular cardiac muscle tissue development GO:0003229 3 0.019
regulation of dendrite morphogenesis GO:0048814 3 0.019
lymph vessel development GO:0001945 27 0.019
negative regulation of protein transport GO:0051224 3 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
cellular response to radiation GO:0071478 4 0.019
regulation of protein depolymerization GO:1901879 1 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
neuron neuron synaptic transmission GO:0007270 1 0.019
ion homeostasis GO:0050801 41 0.019
regulation of cell activation GO:0050865 1 0.018
neuron death GO:0070997 21 0.018
regulation of cell death GO:0010941 103 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
positive regulation of notch signaling pathway GO:0045747 3 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
regulation of cell migration GO:0030334 40 0.018
multicellular organismal metabolic process GO:0044236 2 0.018
positive regulation of transcription dna templated GO:0045893 57 0.018
hormone transport GO:0009914 2 0.018
mitotic cell cycle GO:0000278 64 0.018
centrosome organization GO:0051297 1 0.018
specification of organ identity GO:0010092 2 0.018
toll like receptor signaling pathway GO:0002224 4 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
regulation of response to biotic stimulus GO:0002831 2 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
regulation of metal ion transport GO:0010959 4 0.018
negative regulation of map kinase activity GO:0043407 2 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
divalent inorganic cation homeostasis GO:0072507 22 0.018
skeletal system development GO:0001501 181 0.018
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.017
detection of abiotic stimulus GO:0009582 24 0.017
regulation of vesicle mediated transport GO:0060627 9 0.017
adherens junction organization GO:0034332 4 0.017
regulation of gtpase activity GO:0043087 2 0.017
cell substrate adhesion GO:0031589 4 0.017
regulation of cellular response to growth factor stimulus GO:0090287 35 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
regulation of autophagy GO:0010506 3 0.017
death GO:0016265 121 0.017
endocardium morphogenesis GO:0003160 4 0.017
female meiotic division GO:0007143 2 0.017
positive regulation of ras gtpase activity GO:0032320 1 0.017
detection of stimulus involved in sensory perception GO:0050906 21 0.017
lateral inhibition GO:0046331 1 0.017
regulation of cell projection assembly GO:0060491 4 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
regulation of binding GO:0051098 3 0.017
positive regulation of stem cell proliferation GO:2000648 1 0.017
establishment of mitotic spindle localization GO:0040001 12 0.017
germ line stem cell maintenance GO:0030718 2 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
tube closure GO:0060606 1 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
regulation of endocrine process GO:0044060 2 0.017
mechanoreceptor differentiation GO:0042490 37 0.017
eye morphogenesis GO:0048592 144 0.017
regulation of catalytic activity GO:0050790 55 0.017
segment polarity determination GO:0007367 1 0.016
response to hexose GO:0009746 3 0.016
myoblast fusion GO:0007520 10 0.016
regulation of dna templated transcription in response to stress GO:0043620 0 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
positive regulation of muscle tissue development GO:1901863 1 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
phosphorylation GO:0016310 69 0.016
muscle cell development GO:0055001 115 0.016
spinal cord development GO:0021510 46 0.016
heart process GO:0003015 71 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
regulation of reproductive process GO:2000241 4 0.016
regulation of protein catabolic process GO:0042176 1 0.016
cellular component biogenesis GO:0044085 178 0.016
positive regulation of muscle organ development GO:0048636 1 0.016
regulation of apoptotic process GO:0042981 98 0.016
microtubule organizing center organization GO:0031023 1 0.016
single organism cellular localization GO:1902580 46 0.016
regulation of locomotion GO:0040012 55 0.016
establishment or maintenance of cell polarity GO:0007163 29 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.016
regulation of cell size GO:0008361 29 0.016
neurotransmitter secretion GO:0007269 2 0.016
single organism membrane fusion GO:0044801 2 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
detection of mechanical stimulus GO:0050982 11 0.016
epithelial cell development GO:0002064 42 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.015
notochord development GO:0030903 54 0.015
regulation of blood coagulation GO:0030193 1 0.015
cellular amide metabolic process GO:0043603 4 0.015
neuron projection guidance GO:0097485 86 0.015
multi organism process GO:0051704 134 0.015
epithelial cell migration GO:0010631 25 0.015
regulation of heart growth GO:0060420 2 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
collagen metabolic process GO:0032963 2 0.015
cation homeostasis GO:0055080 33 0.015
aorta development GO:0035904 4 0.015
regulation of neuron differentiation GO:0045664 56 0.015
regulation of mesenchymal cell proliferation GO:0010464 1 0.015
protein complex localization GO:0031503 1 0.015
regulation of neurological system process GO:0031644 2 0.015
antimicrobial humoral response GO:0019730 2 0.015
regulation of protein binding GO:0043393 3 0.015
spindle assembly involved in meiosis GO:0090306 1 0.015
regulation of skeletal muscle fiber development GO:0048742 2 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
trabecula morphogenesis GO:0061383 2 0.015
immune response GO:0006955 28 0.015
spindle localization GO:0051653 12 0.015
response to growth factor GO:0070848 39 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
transmembrane transport GO:0055085 120 0.015
response to endogenous stimulus GO:0009719 83 0.015
inner ear morphogenesis GO:0042472 63 0.015
peptide transport GO:0015833 1 0.015
pronuclear migration GO:0035046 1 0.014
regulation of protein polymerization GO:0032271 2 0.014
cardiac cell fate commitment GO:0060911 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.014
axonal defasciculation GO:0007414 2 0.014
organic substance transport GO:0071702 58 0.014
response to fibroblast growth factor GO:0071774 22 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
ventral spinal cord development GO:0021517 35 0.014
epidermal cell differentiation GO:0009913 36 0.014
regulation of hormone secretion GO:0046883 2 0.014
b cell differentiation GO:0030183 1 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.014
protein phosphorylation GO:0006468 47 0.014

appl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014