Danio rerio

18 known processes

aqp8a.1

aquaporin 8a, tandem duplicate 1

(Aliases: mg:db04c12,aqp8a,zgc:103682,aqp8,db04c12)

aqp8a.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
urea transport GO:0015840 11 0.983
urea transmembrane transport GO:0071918 9 0.983
carbon dioxide transmembrane transport GO:0035378 1 0.913
Zebrafish
one carbon compound transport GO:0019755 14 0.912
fluid transport GO:0042044 17 0.905
ammonium transmembrane transport GO:0072488 2 0.891
Zebrafish
renal absorption GO:0070293 1 0.712
aging GO:0007568 2 0.568
monovalent inorganic cation transport GO:0015672 42 0.509
Zebrafish
response to stress GO:0006950 263 0.386
ammonium transport GO:0015696 6 0.344
Zebrafish
glycerol transport GO:0015793 7 0.318
water transport GO:0006833 15 0.290
vasculature development GO:0001944 278 0.238
kidney vasculature development GO:0061440 2 0.229
regulation of metal ion transport GO:0010959 4 0.220
anion transport GO:0006820 38 0.170
Zebrafish
camera type eye development GO:0043010 222 0.166
Zebrafish
intracellular receptor signaling pathway GO:0030522 30 0.161
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.156
multicellular organismal water homeostasis GO:0050891 1 0.146
single organism transport GO:0044765 206 0.142
regulation of sodium ion transport GO:0002028 2 0.127
response to endogenous stimulus GO:0009719 83 0.117
water homeostasis GO:0030104 4 0.116
polyol transport GO:0015791 7 0.110
amide transport GO:0042886 12 0.104
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.099
blood vessel development GO:0001568 246 0.098
vascular process in circulatory system GO:0003018 6 0.098
ion transport GO:0006811 114 0.096
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.088
regulation of bmp signaling pathway GO:0030510 39 0.085
embryonic heart tube development GO:0035050 133 0.084
single organism metabolic process GO:0044710 217 0.084
cellular response to hormone stimulus GO:0032870 39 0.084
nucleic acid metabolic process GO:0090304 244 0.084
ion transmembrane transport GO:0034220 91 0.081
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.077
nitrogen compound metabolic process GO:0006807 319 0.076
odontogenesis of dentin containing tooth GO:0042475 1 0.073
response to hormone GO:0009725 48 0.070
pericardium development GO:0060039 1 0.068
locomotion GO:0040011 313 0.067
heart looping GO:0001947 94 0.067
regulation of blood vessel size GO:0050880 2 0.066
rna metabolic process GO:0016070 219 0.066
cell motility GO:0048870 244 0.064
localization of cell GO:0051674 244 0.062
response to corticosteroid GO:0031960 1 0.061
cellular response to organic substance GO:0071310 105 0.061
response to organic substance GO:0010033 153 0.061
response to steroid hormone GO:0048545 35 0.060
maintenance of location GO:0051235 4 0.060
cellular response to external stimulus GO:0071496 2 0.059
angiogenesis GO:0001525 158 0.058
cellular response to chemical stimulus GO:0070887 157 0.058
regulation of nitrogen compound metabolic process GO:0051171 251 0.057
regulation of tube size GO:0035150 2 0.055
chemical homeostasis GO:0048878 49 0.055
inorganic anion transport GO:0015698 25 0.055
Zebrafish
response to vitamin b3 GO:0033552 2 0.055
cation transport GO:0006812 81 0.054
Zebrafish
central nervous system development GO:0007417 387 0.054
renal system process GO:0003014 14 0.054
regulation of nucleoside metabolic process GO:0009118 2 0.053
regulation of blood pressure GO:0008217 1 0.052
oxidative demethylation GO:0070989 1 0.051
regulation of systemic arterial blood pressure GO:0003073 1 0.051
response to wounding GO:0009611 116 0.051
wound healing GO:0042060 90 0.049
blood vessel morphogenesis GO:0048514 216 0.049
transmembrane transport GO:0055085 120 0.048
regulation of biosynthetic process GO:0009889 250 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.046
proximal tubule development GO:0072014 3 0.045
negative regulation of heart contraction GO:0045822 2 0.045
response to chemical GO:0042221 320 0.045
nitrogen compound transport GO:0071705 23 0.045
cellular nitrogen compound biosynthetic process GO:0044271 218 0.045
sprouting angiogenesis GO:0002040 53 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.044
cellular response to organic cyclic compound GO:0071407 38 0.044
cellular nitrogen compound metabolic process GO:0034641 290 0.044
transport GO:0006810 220 0.044
morphogenesis of an epithelium GO:0002009 333 0.043
forebrain development GO:0030900 96 0.043
heterocycle biosynthetic process GO:0018130 215 0.043
homeostatic process GO:0042592 142 0.043
renal system vasculature development GO:0061437 2 0.040
metal ion transport GO:0030001 58 0.040
positive regulation of transport GO:0051050 2 0.037
response to nutrient GO:0007584 3 0.037
sensory organ development GO:0007423 393 0.037
Zebrafish
potassium ion transmembrane transport GO:0071805 10 0.037
positive regulation of blood circulation GO:1903524 2 0.037
response to lipid GO:0033993 60 0.037
gas transport GO:0015669 3 0.036
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.036
response to drug GO:0042493 3 0.036
blood vessel endothelial cell migration GO:0043534 18 0.036
regulation of nucleic acid templated transcription GO:1903506 213 0.035
peptide transport GO:0015833 1 0.035
cartilage development GO:0051216 96 0.035
hormone secretion GO:0046879 2 0.035
alcohol biosynthetic process GO:0046165 2 0.035
xenobiotic metabolic process GO:0006805 4 0.034
lateral ventricle development GO:0021670 1 0.034
growth GO:0040007 174 0.033
multicellular organism growth GO:0035264 4 0.033
lateral line system development GO:0048925 76 0.033
lymphatic endothelial cell differentiation GO:0060836 1 0.032
system process GO:0003008 185 0.032
lipid homeostasis GO:0055088 3 0.032
establishment of localization GO:0051234 244 0.031
endocrine process GO:0050886 2 0.031
negative regulation of protein complex assembly GO:0031333 1 0.031
negative regulation of blood circulation GO:1903523 2 0.031
oxoacid metabolic process GO:0043436 31 0.030
cellular response to endogenous stimulus GO:0071495 68 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
cellular sodium ion homeostasis GO:0006883 1 0.029
regulation of biological quality GO:0065008 263 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
cellular biosynthetic process GO:0044249 286 0.029
astrocyte differentiation GO:0048708 1 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.029
positive regulation of catabolic process GO:0009896 4 0.028
response to vitamin GO:0033273 3 0.028
lymphoid lineage cell migration into thymus GO:0097535 4 0.028
osteoclast development GO:0036035 1 0.028
positive regulation of stem cell proliferation GO:2000648 1 0.028
organic substance biosynthetic process GO:1901576 289 0.028
regulation of cellular ph GO:0030641 1 0.028
regulation of fatty acid metabolic process GO:0019217 1 0.028
cellular response to steroid hormone stimulus GO:0071383 31 0.028
hormone transport GO:0009914 2 0.027
response to glucocorticoid GO:0051384 1 0.027
phagocytosis GO:0006909 3 0.027
ventricular system development GO:0021591 12 0.027
heart morphogenesis GO:0003007 156 0.027
signal transduction GO:0007165 455 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.026
epithelial cell migration GO:0010631 25 0.026
carbohydrate homeostasis GO:0033500 1 0.025
eye development GO:0001654 277 0.025
Zebrafish
posterior lateral line system development GO:0048915 46 0.025
cellular amine metabolic process GO:0044106 2 0.025
hepaticobiliary system development GO:0061008 98 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
chordate embryonic development GO:0043009 271 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
regulation of stem cell proliferation GO:0072091 2 0.024
embryonic heart tube morphogenesis GO:0003143 108 0.024
cellular response to lipid GO:0071396 39 0.023
cell death in response to oxidative stress GO:0036473 2 0.023
regulation of cell substrate adhesion GO:0010810 1 0.023
negative regulation of cellular process GO:0048523 283 0.023
sensory perception of pain GO:0019233 1 0.023
response to organic cyclic compound GO:0014070 51 0.022
muscle cell differentiation GO:0042692 139 0.022
innate immune response GO:0045087 13 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
cell substrate junction assembly GO:0007044 2 0.022
lipid digestion GO:0044241 3 0.022
heart development GO:0007507 313 0.022
organic acid metabolic process GO:0006082 31 0.021
organ regeneration GO:0031100 1 0.021
brain development GO:0007420 293 0.021
regeneration GO:0031099 91 0.021
stem cell proliferation GO:0072089 4 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
regulation of transcription dna templated GO:0006355 213 0.021
multicellular organismal metabolic process GO:0044236 2 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
lipid storage GO:0019915 1 0.021
response to glucose GO:0009749 3 0.021
carbon dioxide transport GO:0015670 3 0.021
Zebrafish
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.020
response to hexose GO:0009746 3 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
organelle organization GO:0006996 227 0.020
transcription dna templated GO:0006351 181 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
amine metabolic process GO:0009308 2 0.020
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.019
regulation of vasculature development GO:1901342 33 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
endodermal cell fate determination GO:0007493 2 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
glomerular filtration GO:0003094 6 0.019
pyruvate metabolic process GO:0006090 1 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
single organism biosynthetic process GO:0044711 71 0.019
positive regulation of cellular process GO:0048522 201 0.019
heterocycle metabolic process GO:0046483 290 0.019
retina vasculature development in camera type eye GO:0061298 2 0.019
positive regulation of secretion GO:0051047 1 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
protein targeting to nucleus GO:0044744 3 0.019
bmp signaling pathway GO:0030509 52 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
positive regulation of endothelial cell proliferation GO:0001938 1 0.019
modification of morphology or physiology of other organism GO:0035821 4 0.019
xanthophore differentiation GO:0050936 3 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
regulation of myotube differentiation GO:0010830 2 0.018
defense response GO:0006952 47 0.018
regulation of endothelial cell proliferation GO:0001936 1 0.018
negative regulation of biological process GO:0048519 304 0.018
nucleic acid templated transcription GO:0097659 181 0.017
potassium ion transport GO:0006813 10 0.017
positive regulation of striated muscle cell differentiation GO:0051155 1 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
single organism localization GO:1902578 225 0.017
cellular response to nutrient levels GO:0031669 2 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
cell migration GO:0016477 237 0.017
positive regulation of heart contraction GO:0045823 2 0.017
regulation of cytokine production GO:0001817 3 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
establishment of endothelial barrier GO:0061028 3 0.017
regulation of retina development in camera type eye GO:1902866 2 0.017
immune system process GO:0002376 241 0.017
response to external stimulus GO:0009605 264 0.016
cellular component movement GO:0006928 335 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
toxin metabolic process GO:0009404 1 0.016
cellular aldehyde metabolic process GO:0006081 4 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
rna biosynthetic process GO:0032774 181 0.016
skeletal system development GO:0001501 181 0.016
central nervous system formation GO:0021556 1 0.016
positive regulation of cell cycle GO:0045787 3 0.016
regulation of transporter activity GO:0032409 2 0.016
renal system development GO:0072001 94 0.016
spinal cord development GO:0021510 46 0.016
cation transmembrane transport GO:0098655 65 0.016
Zebrafish
entrainment of circadian clock GO:0009649 2 0.016
regulation of receptor activity GO:0010469 2 0.016
positive regulation of leukocyte migration GO:0002687 2 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
negative regulation of dna replication GO:0008156 2 0.016
membrane repolarization GO:0086009 2 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
response to oxygen containing compound GO:1901700 55 0.015
regulation of dna templated transcription elongation GO:0032784 3 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
intracellular signal transduction GO:0035556 85 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
inorganic anion transmembrane transport GO:0098661 10 0.015
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.015
behavior GO:0007610 74 0.015
skeletal system morphogenesis GO:0048705 102 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
urogenital system development GO:0001655 97 0.015
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.015
positive regulation of biological process GO:0048518 253 0.015
regulation of gtpase activity GO:0043087 2 0.015
cellular potassium ion transport GO:0071804 10 0.015
multi organism process GO:0051704 134 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
inorganic cation transmembrane transport GO:0098662 50 0.014
Zebrafish
sensory system development GO:0048880 76 0.014
neuromast development GO:0048884 46 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
epithelial to mesenchymal transition GO:0001837 21 0.014
endocrine hormone secretion GO:0060986 2 0.014
steroid hormone mediated signaling pathway GO:0043401 9 0.014
small molecule metabolic process GO:0044281 77 0.014
tissue regeneration GO:0042246 74 0.014
collagen metabolic process GO:0032963 2 0.014
digestive tract morphogenesis GO:0048546 231 0.014
liver development GO:0001889 96 0.014
response to nitrogen compound GO:1901698 19 0.014
endocardial cushion formation GO:0003272 2 0.013
regulation of localization GO:0032879 104 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
ameboidal type cell migration GO:0001667 143 0.013
head development GO:0060322 303 0.013
endothelial cell differentiation GO:0045446 20 0.013
anion transmembrane transport GO:0098656 12 0.013
Zebrafish
protein import GO:0017038 3 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
dna templated transcription elongation GO:0006354 3 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
lens development in camera type eye GO:0002088 22 0.012
Zebrafish
positive regulation of leukocyte chemotaxis GO:0002690 1 0.012
cellular response to starvation GO:0009267 1 0.012
retinal metabolic process GO:0042574 3 0.012
smooth muscle contraction GO:0006939 2 0.012
response to abiotic stimulus GO:0009628 122 0.012
single organism nuclear import GO:1902593 3 0.012
tissue remodeling GO:0048771 4 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
regulation of response to interferon gamma GO:0060330 1 0.012
embryonic organ development GO:0048568 381 0.012
response to carbohydrate GO:0009743 3 0.012
regulation of collagen metabolic process GO:0010712 2 0.011
cellular ketone metabolic process GO:0042180 11 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.011
ion homeostasis GO:0050801 41 0.011
positive regulation of camp metabolic process GO:0030816 2 0.011
somitogenesis GO:0001756 87 0.011
endothelium development GO:0003158 25 0.011
neurotransmitter secretion GO:0007269 2 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
fin regeneration GO:0031101 51 0.011
trabecula morphogenesis GO:0061383 2 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of developmental process GO:0050793 247 0.011
lateral line development GO:0048882 66 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
regulation of circadian rhythm GO:0042752 4 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
positive regulation of macrophage chemotaxis GO:0010759 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
lymphoid lineage cell migration GO:0097534 4 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
endocardial cushion morphogenesis GO:0003203 3 0.011
regulation of binding GO:0051098 3 0.011
multicellular organismal response to stress GO:0033555 2 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
regulation of rna metabolic process GO:0051252 224 0.010
detection of temperature stimulus GO:0016048 0 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of cell proliferation GO:0042127 37 0.010
striated muscle cell differentiation GO:0051146 129 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
gtp catabolic process GO:0006184 2 0.010

aqp8a.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
disease by infectious agent DOID:0050117 0 0.018
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.011