Danio rerio

18 known processes

aqp8a.2

aquaporin 8a, tandem duplicate 2

(Aliases: zgc:158752,MGC158752)

aqp8a.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
water transport GO:0006833 15 0.981
fluid transport GO:0042044 17 0.902
inorganic anion transport GO:0015698 25 0.768
Zebrafish
urea transport GO:0015840 11 0.761
urea transmembrane transport GO:0071918 9 0.696
polyol transport GO:0015791 7 0.659
glycerol transport GO:0015793 7 0.409
anion transport GO:0006820 38 0.319
Zebrafish Rat
ion transmembrane transport GO:0034220 91 0.315
Zebrafish
ion transport GO:0006811 114 0.306
Zebrafish Rat
ammonium transmembrane transport GO:0072488 2 0.234
Zebrafish
cellular response to estrogen stimulus GO:0071391 24 0.198
transmembrane transport GO:0055085 120 0.174
aging GO:0007568 2 0.165
defense response to bacterium GO:0042742 22 0.158
response to biotic stimulus GO:0009607 97 0.132
carbohydrate transport GO:0008643 13 0.118
establishment of localization GO:0051234 244 0.112
immune system process GO:0002376 241 0.091
defense response GO:0006952 47 0.091
response to other organism GO:0051707 97 0.089
nitrogen compound transport GO:0071705 23 0.084
defense response to other organism GO:0098542 33 0.077
renal absorption GO:0070293 1 0.074
amide transport GO:0042886 12 0.073
response to external biotic stimulus GO:0043207 97 0.068
transport GO:0006810 220 0.058
larval development GO:0002164 2 0.057
response to stress GO:0006950 263 0.048
single organism transport GO:0044765 206 0.047
eye development GO:0001654 277 0.045
Zebrafish
regulation of cytokine production GO:0001817 3 0.045
homeostatic process GO:0042592 142 0.045
water homeostasis GO:0030104 4 0.044
gas transport GO:0015669 3 0.044
Zebrafish
anion transmembrane transport GO:0098656 12 0.043
Zebrafish
response to external stimulus GO:0009605 264 0.043
defense response to gram negative bacterium GO:0050829 8 0.042
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.041
single organism localization GO:1902578 225 0.037
cation transport GO:0006812 81 0.036
Zebrafish
organic hydroxy compound transport GO:0015850 14 0.036
Rat
positive regulation of cell cycle GO:0045787 3 0.036
lipid storage GO:0019915 1 0.036
response to drug GO:0042493 3 0.035
multi organism process GO:0051704 134 0.035
endosome organization GO:0007032 2 0.035
lipid catabolic process GO:0016042 4 0.035
regulation of muscle contraction GO:0006937 3 0.034
positive regulation of biosynthetic process GO:0009891 68 0.033
regulation of ph GO:0006885 3 0.033
tube morphogenesis GO:0035239 349 0.032
regulation of cellular ph GO:0030641 1 0.032
multicellular organism growth GO:0035264 4 0.031
sensory organ development GO:0007423 393 0.031
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.030
regulation of metal ion transport GO:0010959 4 0.030
response to chemical GO:0042221 320 0.030
Human
phagocytosis GO:0006909 3 0.028
maintenance of location GO:0051235 4 0.028
system process GO:0003008 185 0.028
organic substance biosynthetic process GO:1901576 289 0.028
multicellular organismal water homeostasis GO:0050891 1 0.027
response to glucocorticoid GO:0051384 1 0.027
stem cell maintenance GO:0019827 4 0.027
carbon dioxide transmembrane transport GO:0035378 1 0.026
Zebrafish
response to carbohydrate GO:0009743 3 0.026
regulation of sodium ion transport GO:0002028 2 0.026
immune response GO:0006955 28 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
innate immune response GO:0045087 13 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
hormone transport GO:0009914 2 0.025
smooth muscle contraction GO:0006939 2 0.024
positive regulation of catabolic process GO:0009896 4 0.023
cellular lipid catabolic process GO:0044242 3 0.023
positive regulation of camp metabolic process GO:0030816 2 0.023
peptidyl lysine acetylation GO:0018394 2 0.023
adult behavior GO:0030534 2 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.023
glucose homeostasis GO:0042593 1 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
carbon dioxide transport GO:0015670 3 0.022
Zebrafish
regulation of systemic arterial blood pressure GO:0003073 1 0.022
atp catabolic process GO:0006200 4 0.022
regulation of lyase activity GO:0051339 12 0.022
positive regulation of transport GO:0051050 2 0.022
one carbon compound transport GO:0019755 14 0.022
hormone secretion GO:0046879 2 0.021
regulation of neurological system process GO:0031644 2 0.021
nuclear transport GO:0051169 4 0.020
lipid homeostasis GO:0055088 3 0.020
response to glucose GO:0009749 3 0.020
protein homooligomerization GO:0051260 3 0.020
regulation of biological quality GO:0065008 263 0.020
mitochondrion organization GO:0007005 4 0.020
cellular amine metabolic process GO:0044106 2 0.020
digestive system development GO:0055123 289 0.020
dicarboxylic acid transport GO:0006835 1 0.019
regulation of blood pressure GO:0008217 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
meiotic cell cycle process GO:1903046 3 0.019
response to hexose GO:0009746 3 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
signal transduction GO:0007165 455 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
inorganic anion transmembrane transport GO:0098661 10 0.018
Zebrafish
response to monosaccharide GO:0034284 3 0.018
cyclic nucleotide biosynthetic process GO:0009190 18 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
regulation of hormone secretion GO:0046883 2 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
monovalent inorganic cation transport GO:0015672 42 0.018
Zebrafish
positive regulation of immune effector process GO:0002699 3 0.018
positive regulation of secretion GO:0051047 1 0.018
establishment of endothelial barrier GO:0061028 3 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
negative regulation of cytokine production GO:0001818 1 0.017
protein acetylation GO:0006473 2 0.017
renal system process GO:0003014 14 0.017
response to bacterium GO:0009617 58 0.017
amine metabolic process GO:0009308 2 0.017
response to corticosteroid GO:0031960 1 0.017
sensory perception of chemical stimulus GO:0007606 3 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
leukocyte proliferation GO:0070661 1 0.017
digestive tract morphogenesis GO:0048546 231 0.017
regulation of reproductive process GO:2000241 4 0.017
positive regulation of blood circulation GO:1903524 2 0.017
protein import GO:0017038 3 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
heterocycle metabolic process GO:0046483 290 0.017
inorganic ion transmembrane transport GO:0098660 57 0.016
Zebrafish
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.016
gastrulation GO:0007369 208 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
epithelial cell morphogenesis GO:0003382 2 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
membrane lipid biosynthetic process GO:0046467 2 0.016
lateral inhibition GO:0046331 1 0.016
nucleotide biosynthetic process GO:0009165 21 0.016
ion homeostasis GO:0050801 41 0.016
regulation of blood vessel size GO:0050880 2 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
rna localization GO:0006403 4 0.016
endocrine process GO:0050886 2 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
positive regulation of cell division GO:0051781 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
organic substance transport GO:0071702 58 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
negative regulation of catabolic process GO:0009895 3 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
biosynthetic process GO:0009058 294 0.015
regulation of inflammatory response GO:0050727 2 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
cellular component disassembly GO:0022411 1 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
Zebrafish
carbohydrate homeostasis GO:0033500 1 0.015
organism emergence from protective structure GO:0071684 4 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
purine nucleotide biosynthetic process GO:0006164 20 0.015
regulation of tube size GO:0035150 2 0.015
interspecies interaction between organisms GO:0044419 4 0.015
cellular response to nutrient levels GO:0031669 2 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
monocarboxylic acid catabolic process GO:0072329 3 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
cellular ketone metabolic process GO:0042180 11 0.015
nucleic acid templated transcription GO:0097659 181 0.015
cell migration GO:0016477 237 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
protein acylation GO:0043543 3 0.015
gtp metabolic process GO:0046039 4 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
cellular response to starvation GO:0009267 1 0.015
meiotic nuclear division GO:0007126 4 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
small molecule catabolic process GO:0044282 3 0.014
g protein coupled receptor signaling pathway GO:0007186 74 0.014
peptide transport GO:0015833 1 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
sensory perception of pain GO:0019233 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
neurotransmitter transport GO:0006836 2 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
cognition GO:0050890 1 0.014
multicellular organismal response to stress GO:0033555 2 0.014
regulation of protein catabolic process GO:0042176 1 0.014
tissue remodeling GO:0048771 4 0.014
chemosensory behavior GO:0007635 1 0.014
response to nutrient GO:0007584 3 0.014
neurotransmitter secretion GO:0007269 2 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
chemical homeostasis GO:0048878 49 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
organonitrogen compound biosynthetic process GO:1901566 47 0.014
compound eye development GO:0048749 2 0.014
gtp catabolic process GO:0006184 2 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
locomotion GO:0040011 313 0.014
fatty acid catabolic process GO:0009062 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
lymphocyte proliferation GO:0046651 1 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
regulation of binding GO:0051098 3 0.013
protein complex disassembly GO:0043241 1 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
regulation of transporter activity GO:0032409 2 0.013
rna biosynthetic process GO:0032774 181 0.013
regulation of intracellular ph GO:0051453 1 0.013
fatty acid beta oxidation GO:0006635 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
cation transmembrane transport GO:0098655 65 0.013
Zebrafish
vasculature development GO:0001944 278 0.013
regulation of biosynthetic process GO:0009889 250 0.013
nucleic acid metabolic process GO:0090304 244 0.013
stem cell division GO:0017145 1 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
response to organic substance GO:0010033 153 0.013
Human
membrane invagination GO:0010324 1 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
mononuclear cell proliferation GO:0032943 1 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
epithelial cell differentiation GO:0030855 116 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
spermatid differentiation GO:0048515 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of nucleotide biosynthetic process GO:0030808 15 0.012
regulation of protein complex assembly GO:0043254 3 0.012
single organism biosynthetic process GO:0044711 71 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
post embryonic organ development GO:0048569 4 0.012
protein import into nucleus GO:0006606 3 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
cellular component biogenesis GO:0044085 178 0.012
regulation of protein transport GO:0051223 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
golgi vesicle transport GO:0048193 3 0.012
response to topologically incorrect protein GO:0035966 2 0.012
ovulation cycle process GO:0022602 2 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
negative regulation of biological process GO:0048519 304 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
somatic muscle development GO:0007525 4 0.012
stem cell proliferation GO:0072089 4 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
sensory organ morphogenesis GO:0090596 200 0.012
response to amino acid GO:0043200 2 0.012
germ line stem cell maintenance GO:0030718 2 0.012
lateral line system development GO:0048925 76 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
exocytosis GO:0006887 1 0.012
sphingolipid biosynthetic process GO:0030148 2 0.012
leukocyte mediated cytotoxicity GO:0001909 1 0.012
negative regulation of secretion GO:0051048 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
cellular homeostasis GO:0019725 26 0.012
regulation of protein binding GO:0043393 3 0.012
transcription dna templated GO:0006351 181 0.011
spermatid development GO:0007286 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
lateral line development GO:0048882 66 0.011
camera type eye development GO:0043010 222 0.011
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
b cell activation GO:0042113 2 0.011
fertilization GO:0009566 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
cell aging GO:0007569 2 0.011
synaptic vesicle localization GO:0097479 1 0.011
cellular component assembly GO:0022607 170 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
single organism metabolic process GO:0044710 217 0.011
cellular component movement GO:0006928 335 0.011
neuropeptide signaling pathway GO:0007218 11 0.011
cellular protein catabolic process GO:0044257 4 0.011
proximal tubule development GO:0072014 3 0.011
nuclear import GO:0051170 3 0.011
cellular biosynthetic process GO:0044249 286 0.011
negative regulation of defense response GO:0031348 2 0.011
ammonium transport GO:0015696 6 0.011
Zebrafish
oxoacid metabolic process GO:0043436 31 0.011
sensory system development GO:0048880 76 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
cellular amide metabolic process GO:0043603 4 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
positive regulation of translation GO:0045727 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
cytokinesis GO:0000910 3 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
single organism nuclear import GO:1902593 3 0.011
calcium mediated signaling GO:0019722 2 0.010
response to wounding GO:0009611 116 0.010
protein targeting to nucleus GO:0044744 3 0.010
positive regulation of biological process GO:0048518 253 0.010
cellular response to radiation GO:0071478 4 0.010
neuromast development GO:0048884 46 0.010
rna metabolic process GO:0016070 219 0.010
protein localization to plasma membrane GO:0072659 1 0.010
cellular response to hormone stimulus GO:0032870 39 0.010
positive regulation of metabolic process GO:0009893 108 0.010
translational initiation GO:0006413 3 0.010
mitochondrial transport GO:0006839 2 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
antimicrobial humoral response GO:0019730 2 0.010
somite development GO:0061053 96 0.010
neurological system process GO:0050877 62 0.010
fatty acid transport GO:0015908 1 0.010
regulation of metabolic process GO:0019222 359 0.010
muscle cell differentiation GO:0042692 139 0.010
amino acid transport GO:0006865 2 0.010
ribonucleotide biosynthetic process GO:0009260 20 0.010
positive regulation of cytokine production GO:0001819 2 0.010
morphogenesis of an epithelial sheet GO:0002011 49 0.010
small molecule metabolic process GO:0044281 77 0.010
positive regulation of epithelial cell migration GO:0010634 2 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
single fertilization GO:0007338 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
protein localization to nucleus GO:0034504 3 0.010
metal ion transport GO:0030001 58 0.010
female gonad development GO:0008585 4 0.010

aqp8a.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
musculoskeletal system disease DOID:17 0 0.015
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.015
disease of metabolism DOID:0014667 0 0.015
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011