Danio rerio

16 known processes

arap3

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

arap3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel development GO:0001568 246 0.398
tube morphogenesis GO:0035239 349 0.346
vasculature development GO:0001944 278 0.318
cell motility GO:0048870 244 0.200
digestive tract morphogenesis GO:0048546 231 0.194
localization of cell GO:0051674 244 0.193
sprouting angiogenesis GO:0002040 53 0.190
blood vessel morphogenesis GO:0048514 216 0.186
patterning of blood vessels GO:0001569 15 0.175
locomotion GO:0040011 313 0.150
morphogenesis of an epithelium GO:0002009 333 0.149
cellular component movement GO:0006928 335 0.144
lymph vessel development GO:0001945 27 0.135
sensory organ development GO:0007423 393 0.105
ameboidal type cell migration GO:0001667 143 0.100
angiogenesis GO:0001525 158 0.099
signal transduction GO:0007165 455 0.096
negative regulation of blood circulation GO:1903523 2 0.086
determination of bilateral symmetry GO:0009855 204 0.084
regulation of cell communication GO:0010646 232 0.084
cell migration GO:0016477 237 0.077
immune system process GO:0002376 241 0.076
heart development GO:0007507 313 0.075
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.074
neuroblast proliferation GO:0007405 2 0.073
regulation of vasculature development GO:1901342 33 0.071
lymphangiogenesis GO:0001946 25 0.068
cell substrate adhesion GO:0031589 4 0.065
regulation of cellular metabolic process GO:0031323 320 0.065
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.064
regulation of tube size GO:0035150 2 0.064
cellular nitrogen compound metabolic process GO:0034641 290 0.064
negative regulation of angiogenesis GO:0016525 7 0.063
epithelial tube morphogenesis GO:0060562 148 0.062
macrophage chemotaxis GO:0048246 3 0.062
digestive tract development GO:0048565 265 0.059
regulation of signaling GO:0023051 235 0.059
germ line stem cell maintenance GO:0030718 2 0.059
stem cell proliferation GO:0072089 4 0.058
nitrogen compound metabolic process GO:0006807 319 0.058
regulation of neural precursor cell proliferation GO:2000177 3 0.054
regulation of response to stimulus GO:0048583 269 0.051
regulation of macromolecule biosynthetic process GO:0010556 225 0.051
regulation of cellular response to growth factor stimulus GO:0090287 35 0.050
specification of symmetry GO:0009799 204 0.049
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.049
positive regulation of cell cycle GO:0045787 3 0.049
hematopoietic or lymphoid organ development GO:0048534 191 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.047
positive regulation of endothelial cell proliferation GO:0001938 1 0.046
positive regulation of transport GO:0051050 2 0.046
regulation of cell substrate adhesion GO:0010810 1 0.046
regulation of nitrogen compound metabolic process GO:0051171 251 0.045
regulation of rna biosynthetic process GO:2001141 213 0.045
organic substance biosynthetic process GO:1901576 289 0.045
embryonic heart tube development GO:0035050 133 0.045
negative regulation of tor signaling GO:0032007 2 0.044
positive regulation of cellular metabolic process GO:0031325 94 0.044
regulation of blood vessel size GO:0050880 2 0.044
adherens junction organization GO:0034332 4 0.043
skeletal system development GO:0001501 181 0.043
gastrulation GO:0007369 208 0.043
glial cell migration GO:0008347 3 0.040
biosynthetic process GO:0009058 294 0.040
amino acid transport GO:0006865 2 0.039
positive regulation of cell matrix adhesion GO:0001954 1 0.039
formation of primary germ layer GO:0001704 62 0.039
cellular macromolecule metabolic process GO:0044260 391 0.038
cellular macromolecule biosynthetic process GO:0034645 224 0.038
cell matrix adhesion GO:0007160 4 0.038
organic cyclic compound metabolic process GO:1901360 301 0.038
synaptic growth at neuromuscular junction GO:0051124 2 0.038
regulation of systemic arterial blood pressure GO:0003073 1 0.038
cell surface receptor signaling pathway GO:0007166 325 0.037
positive regulation of phospholipase c activity GO:0010863 1 0.037
lymph vessel morphogenesis GO:0036303 25 0.037
artery development GO:0060840 22 0.037
embryonic organ development GO:0048568 381 0.037
embryonic organ morphogenesis GO:0048562 274 0.037
regulation of anatomical structure morphogenesis GO:0022603 130 0.037
rna metabolic process GO:0016070 219 0.037
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.036
inositol lipid mediated signaling GO:0048017 2 0.036
digestive system development GO:0055123 289 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
branching morphogenesis of an epithelial tube GO:0048754 15 0.035
intracellular signal transduction GO:0035556 85 0.035
regulation of muscle contraction GO:0006937 3 0.035
organelle organization GO:0006996 227 0.035
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.035
determination of left right symmetry GO:0007368 179 0.035
positive regulation of biological process GO:0048518 253 0.034
actin filament based process GO:0030029 64 0.034
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.034
regulation of stem cell proliferation GO:0072091 2 0.034
ventricular cardiac muscle tissue development GO:0003229 3 0.034
renal system development GO:0072001 94 0.033
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.033
morphogenesis of an epithelial sheet GO:0002011 49 0.033
trabecula formation GO:0060343 2 0.033
regulation of erk1 and erk2 cascade GO:0070372 4 0.032
morphogenesis of a branching epithelium GO:0061138 16 0.032
negative regulation of protein complex assembly GO:0031333 1 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
homeostatic process GO:0042592 142 0.032
regulation of transcription dna templated GO:0006355 213 0.032
regulation of cell shape GO:0008360 1 0.031
aromatic compound biosynthetic process GO:0019438 217 0.031
regulation of angiogenesis GO:0045765 26 0.031
system process GO:0003008 185 0.030
nephron tubule morphogenesis GO:0072078 1 0.030
regulation of multicellular organismal development GO:2000026 223 0.030
macromolecule biosynthetic process GO:0009059 227 0.030
rna biosynthetic process GO:0032774 181 0.030
blood circulation GO:0008015 87 0.029
convergent extension GO:0060026 118 0.029
regulation of epithelial cell proliferation GO:0050678 3 0.029
positive regulation of blood circulation GO:1903524 2 0.029
establishment of localization GO:0051234 244 0.028
regulation of biosynthetic process GO:0009889 250 0.028
stem cell maintenance GO:0019827 4 0.028
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.028
phagocytosis engulfment GO:0006911 1 0.028
regulation of endothelial cell proliferation GO:0001936 1 0.028
negative regulation of synapse assembly GO:0051964 2 0.028
cell migration involved in sprouting angiogenesis GO:0002042 8 0.028
trabecula morphogenesis GO:0061383 2 0.028
lateral inhibition GO:0046331 1 0.027
signal transduction in absence of ligand GO:0038034 1 0.027
regulation of cytokine production GO:0001817 3 0.027
amine metabolic process GO:0009308 2 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
smooth muscle contraction GO:0006939 2 0.027
cell morphogenesis GO:0000902 289 0.026
regulation of metabolic process GO:0019222 359 0.026
transcription dna templated GO:0006351 181 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
heart morphogenesis GO:0003007 156 0.025
cellular amine metabolic process GO:0044106 2 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
positive regulation of cell communication GO:0010647 56 0.025
positive regulation of secretion GO:0051047 1 0.025
eye development GO:0001654 277 0.025
regulation of blood pressure GO:0008217 1 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
heterocycle metabolic process GO:0046483 290 0.024
dicarboxylic acid transport GO:0006835 1 0.024
phagocytosis GO:0006909 3 0.024
regulation of dna replication GO:0006275 3 0.023
mesenchyme development GO:0060485 127 0.023
phosphatidylinositol mediated signaling GO:0048015 2 0.023
retina development in camera type eye GO:0060041 146 0.023
regulation of phospholipase c activity GO:1900274 1 0.023
g protein coupled receptor signaling pathway GO:0007186 74 0.023
gene expression GO:0010467 252 0.022
regulation of protein transport GO:0051223 3 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
regulation of cell migration GO:0030334 40 0.021
cellular component assembly GO:0022607 170 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
endocrine process GO:0050886 2 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
positive regulation of map kinase activity GO:0043406 3 0.021
single organism transport GO:0044765 206 0.021
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.021
connective tissue development GO:0061448 99 0.021
pericardium morphogenesis GO:0003344 1 0.021
morphogenesis of a branching structure GO:0001763 21 0.020
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.020
pericardium development GO:0060039 1 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
regulation of primary metabolic process GO:0080090 311 0.020
nephron epithelium development GO:0072009 16 0.020
negative regulation of biological process GO:0048519 304 0.020
hemopoiesis GO:0030097 183 0.020
regulation of developmental process GO:0050793 247 0.019
regulation of autophagy GO:0010506 3 0.019
hypothalamus cell differentiation GO:0021979 4 0.019
water homeostasis GO:0030104 4 0.019
regulation of chemotaxis GO:0050920 18 0.019
primitive hemopoiesis GO:0060215 27 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
monovalent inorganic cation transport GO:0015672 42 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
exocytosis GO:0006887 1 0.018
positive regulation of leukocyte chemotaxis GO:0002690 1 0.018
regulation of locomotion GO:0040012 55 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
regulation of protein complex assembly GO:0043254 3 0.018
regulation of rna metabolic process GO:0051252 224 0.018
single organism localization GO:1902578 225 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of lymphangiogenesis GO:1901490 4 0.018
cation transport GO:0006812 81 0.018
positive regulation of neutrophil migration GO:1902624 0 0.018
regulation of biological quality GO:0065008 263 0.018
actin cytoskeleton organization GO:0030036 63 0.018
sensory organ morphogenesis GO:0090596 200 0.017
nephron epithelium morphogenesis GO:0072088 1 0.017
regulation of heart contraction GO:0008016 32 0.017
positive regulation of signal transduction GO:0009967 56 0.017
angioblast cell migration GO:0035476 9 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
epithelium migration GO:0090132 25 0.017
growth GO:0040007 174 0.017
positive regulation of cell substrate adhesion GO:0010811 1 0.017
maintenance of location GO:0051235 4 0.017
melanocyte migration GO:0097324 4 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
heart contraction GO:0060047 71 0.017
negative regulation of cellular process GO:0048523 283 0.017
aging GO:0007568 2 0.017
regulation of organelle assembly GO:1902115 4 0.017
positive regulation of catabolic process GO:0009896 4 0.017
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.016
response to stress GO:0006950 263 0.016
septum transversum development GO:0003343 4 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
cell projection assembly GO:0030031 64 0.016
phosphorus metabolic process GO:0006793 109 0.016
locomotor rhythm GO:0045475 3 0.016
regulation of signal transduction GO:0009966 225 0.016
cellular protein metabolic process GO:0044267 129 0.016
single organism organelle organization GO:1902589 199 0.016
protein import into nucleus GO:0006606 3 0.016
cellular response to growth factor stimulus GO:0071363 39 0.016
cartilage development GO:0051216 96 0.016
autophagy GO:0006914 4 0.016
regulation of metal ion transport GO:0010959 4 0.016
regulation of cell matrix adhesion GO:0001952 1 0.015
positive regulation of leukocyte migration GO:0002687 2 0.015
regulation of cellular component movement GO:0051270 55 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
stem cell development GO:0048864 82 0.015
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.015
positive regulation of neural precursor cell proliferation GO:2000179 1 0.015
regulation of phospholipase activity GO:0010517 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of circadian rhythm GO:0042752 4 0.015
apoptotic process GO:0006915 116 0.015
hepaticobiliary system development GO:0061008 98 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
tissue migration GO:0090130 37 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
cellular response to oxygen levels GO:0071453 1 0.014
regulation of retina development in camera type eye GO:1902866 2 0.014
larval development GO:0002164 2 0.014
tissue remodeling GO:0048771 4 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
neurological system process GO:0050877 62 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
blood vessel endothelial cell migration GO:0043534 18 0.014
cellular component morphogenesis GO:0032989 336 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
cellular ketone metabolic process GO:0042180 11 0.014
mesenchymal cell development GO:0014031 78 0.014
cellular response to organic substance GO:0071310 105 0.014
ras protein signal transduction GO:0007265 7 0.014
macromolecular complex disassembly GO:0032984 1 0.014
skeletal system morphogenesis GO:0048705 102 0.014
gtp catabolic process GO:0006184 2 0.014
eye morphogenesis GO:0048592 144 0.014
oxoacid metabolic process GO:0043436 31 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
regulation of oligodendrocyte differentiation GO:0048713 1 0.014
regulation of localization GO:0032879 104 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
dorsal aorta morphogenesis GO:0035912 3 0.014
aorta morphogenesis GO:0035909 3 0.014
lipid storage GO:0019915 1 0.013
regulation of organ growth GO:0046620 3 0.013
protein import GO:0017038 3 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
regulation of cell motility GO:2000145 46 0.013
regulation of reproductive process GO:2000241 4 0.013
positive regulation of positive chemotaxis GO:0050927 4 0.013
positive regulation of cellular process GO:0048522 201 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
vasculogenesis GO:0001570 41 0.013
regulation of inflammatory response GO:0050727 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
cytokinesis GO:0000910 3 0.013
endothelial cell differentiation GO:0045446 20 0.013
nucleic acid metabolic process GO:0090304 244 0.013
negative regulation of epithelial cell migration GO:0010633 1 0.013
regulation of protein catabolic process GO:0042176 1 0.013
positive regulation of histone modification GO:0031058 1 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
regulation of vasculogenesis GO:2001212 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of lipase activity GO:0060191 2 0.012
cognition GO:0050890 1 0.012
regulation of cellular component organization GO:0051128 86 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
positive regulation of inflammatory response GO:0050729 1 0.012
neural crest cell differentiation GO:0014033 72 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
response to growth factor GO:0070848 39 0.012
protein metabolic process GO:0019538 183 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
regeneration GO:0031099 91 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
negative regulation of heart contraction GO:0045822 2 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
regulation of synapse organization GO:0050807 3 0.012
lateral line system development GO:0048925 76 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
neural retina development GO:0003407 49 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
notch signaling pathway GO:0007219 35 0.012
multi organism process GO:0051704 134 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
response to wounding GO:0009611 116 0.011
urogenital system development GO:0001655 97 0.011
protein secretion GO:0009306 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
centrosome organization GO:0051297 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
protein localization to nucleus GO:0034504 3 0.011
myeloid cell differentiation GO:0030099 86 0.011
heart looping GO:0001947 94 0.011
protein modification process GO:0036211 100 0.011
cell substrate junction assembly GO:0007044 2 0.011
mesoderm development GO:0007498 88 0.011
outflow tract morphogenesis GO:0003151 1 0.011
endodermal cell fate commitment GO:0001711 18 0.011
response to decreased oxygen levels GO:0036293 25 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
negative chemotaxis GO:0050919 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
transport GO:0006810 220 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
macromolecule modification GO:0043412 111 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.011
establishment of localization in cell GO:0051649 77 0.011
regulation of chronic inflammatory response GO:0002676 1 0.011
negative regulation of developmental process GO:0051093 65 0.011
positive regulation of molecular function GO:0044093 33 0.011
urea transmembrane transport GO:0071918 9 0.011
proepicardium development GO:0003342 4 0.011
cellular response to external stimulus GO:0071496 2 0.011
positive regulation of exocytosis GO:0045921 1 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
centrosome cycle GO:0007098 1 0.011
cardiac cell fate commitment GO:0060911 1 0.011
circulatory system process GO:0003013 87 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
cellular biosynthetic process GO:0044249 286 0.010
sensory perception of pain GO:0019233 1 0.010
regulation of receptor mediated endocytosis GO:0048259 4 0.010
positive regulation of immune effector process GO:0002699 3 0.010
regulation of exocytosis GO:0017157 1 0.010
regulation of fatty acid metabolic process GO:0019217 1 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
angioblast cell migration from lateral mesoderm to midline GO:0035479 4 0.010
positive regulation of epithelial cell migration GO:0010634 2 0.010
cell migration involved in heart development GO:0060973 22 0.010
response to external biotic stimulus GO:0043207 97 0.010
endothelial cell migration GO:0043542 19 0.010
pigment cell differentiation GO:0050931 38 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
embryonic hemopoiesis GO:0035162 53 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
smad protein complex assembly GO:0007183 1 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
mesoderm formation GO:0001707 43 0.010
nuclear import GO:0051170 3 0.010
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.010
synaptic vesicle localization GO:0097479 1 0.010
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.010
neural crest cell development GO:0014032 62 0.010
chemotaxis GO:0006935 104 0.010

arap3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
cardiovascular system disease DOID:1287 0 0.028
nervous system disease DOID:863 0 0.026
disease of cellular proliferation DOID:14566 0 0.013
musculoskeletal system disease DOID:17 0 0.011