Danio rerio

0 known processes

arhgap11a

Rho GTPase activating protein 11A

(Aliases: wu:fc02e04,wu:fc55g06,wu:fe01b01,zgc:77004)

arhgap11a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule organizing center organization GO:0031023 1 0.486
centrosome organization GO:0051297 1 0.320
cellular macromolecule metabolic process GO:0044260 391 0.310
meiotic nuclear division GO:0007126 4 0.200
negative regulation of biological process GO:0048519 304 0.199
positive regulation of cell cycle GO:0045787 3 0.168
mitotic g2 dna damage checkpoint GO:0007095 3 0.160
centrosome cycle GO:0007098 1 0.143
nitrogen compound metabolic process GO:0006807 319 0.142
regulation of cell cycle GO:0051726 52 0.138
centrosome duplication GO:0051298 1 0.133
positive regulation of biological process GO:0048518 253 0.129
nuclear transport GO:0051169 4 0.128
mitotic cell cycle GO:0000278 64 0.122
single organism nuclear import GO:1902593 3 0.115
cellular nitrogen compound metabolic process GO:0034641 290 0.113
cellular aromatic compound metabolic process GO:0006725 295 0.110
mitotic cell cycle embryonic GO:0045448 2 0.110
regulation of response to stimulus GO:0048583 269 0.104
embryonic organ development GO:0048568 381 0.095
mitotic g2 m transition checkpoint GO:0044818 3 0.095
nucleocytoplasmic transport GO:0006913 4 0.094
nucleobase containing compound metabolic process GO:0006139 274 0.091
regulation of multicellular organism growth GO:0040014 4 0.091
regulation of microtubule cytoskeleton organization GO:0070507 3 0.090
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.090
spermatid development GO:0007286 2 0.089
heterocycle metabolic process GO:0046483 290 0.088
microtubule polymerization or depolymerization GO:0031109 3 0.086
regulation of meiotic cell cycle GO:0051445 1 0.086
cellular component biogenesis GO:0044085 178 0.086
regulation of protein complex assembly GO:0043254 3 0.085
g2 dna damage checkpoint GO:0031572 3 0.084
cell cycle process GO:0022402 53 0.083
aging GO:0007568 2 0.083
regulation of protein ubiquitination GO:0031396 3 0.082
tube morphogenesis GO:0035239 349 0.080
translational initiation GO:0006413 3 0.078
cellular macromolecule biosynthetic process GO:0034645 224 0.078
single organism organelle organization GO:1902589 199 0.077
cell cycle g2 m phase transition GO:0044839 4 0.076
cellular component morphogenesis GO:0032989 336 0.074
heart development GO:0007507 313 0.069
regulation of protein catabolic process GO:0042176 1 0.069
vasculature development GO:0001944 278 0.067
mitotic cell cycle process GO:1903047 48 0.066
cytokinesis GO:0000910 3 0.065
cell cycle GO:0007049 93 0.064
regulation of rna metabolic process GO:0051252 224 0.064
regulation of cell cycle process GO:0010564 20 0.063
organic cyclic compound metabolic process GO:1901360 301 0.063
nucleic acid metabolic process GO:0090304 244 0.063
cellular component disassembly GO:0022411 1 0.063
cellular component assembly GO:0022607 170 0.063
mitotic dna damage checkpoint GO:0044773 4 0.062
regulation of macromolecule biosynthetic process GO:0010556 225 0.061
response to drug GO:0042493 3 0.060
developmental maturation GO:0021700 34 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.060
signal transduction GO:0007165 455 0.060
protein import GO:0017038 3 0.059
positive regulation of transport GO:0051050 2 0.058
single organism membrane fusion GO:0044801 2 0.056
regulation of signaling GO:0023051 235 0.055
regulation of intracellular protein transport GO:0033157 3 0.055
positive regulation of catabolic process GO:0009896 4 0.054
positive regulation of cellular process GO:0048522 201 0.054
modification dependent macromolecule catabolic process GO:0043632 3 0.054
positive regulation of cellular catabolic process GO:0031331 3 0.053
regulation of macromolecule metabolic process GO:0060255 317 0.053
meiosis i GO:0007127 1 0.053
multicellular organism growth GO:0035264 4 0.052
gene expression GO:0010467 252 0.051
g2 m transition of mitotic cell cycle GO:0000086 4 0.051
establishment of protein localization to organelle GO:0072594 4 0.051
protein localization to nucleus GO:0034504 3 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
macromolecule biosynthetic process GO:0009059 227 0.048
larval development GO:0002164 2 0.048
regulation of biosynthetic process GO:0009889 250 0.048
ubiquitin dependent protein catabolic process GO:0006511 3 0.047
nuclear division GO:0000280 23 0.047
cell motility GO:0048870 244 0.046
regulation of establishment of protein localization GO:0070201 4 0.046
regulation of protein targeting GO:1903533 2 0.046
single organism metabolic process GO:0044710 217 0.046
positive regulation of metabolic process GO:0009893 108 0.046
negative regulation of protein complex assembly GO:0031333 1 0.045
spindle assembly GO:0051225 2 0.045
regulation of localization GO:0032879 104 0.044
positive regulation of response to stimulus GO:0048584 80 0.044
microtubule depolymerization GO:0007019 1 0.044
cellular protein catabolic process GO:0044257 4 0.044
primary neural tube formation GO:0014020 1 0.043
cellular nitrogen compound biosynthetic process GO:0044271 218 0.043
regulation of cellular metabolic process GO:0031323 320 0.041
dna metabolic process GO:0006259 27 0.041
spermatid differentiation GO:0048515 2 0.041
regulation of nitrogen compound metabolic process GO:0051171 251 0.041
response to abiotic stimulus GO:0009628 122 0.040
organic substance biosynthetic process GO:1901576 289 0.040
nuclear import GO:0051170 3 0.040
cilium morphogenesis GO:0060271 85 0.040
protein complex subunit organization GO:0071822 46 0.040
meiotic cell cycle process GO:1903046 3 0.039
regulation of biological quality GO:0065008 263 0.039
biosynthetic process GO:0009058 294 0.039
spindle assembly involved in mitosis GO:0090307 1 0.039
regulation of mitotic cell cycle GO:0007346 25 0.039
regulation of metabolic process GO:0019222 359 0.038
protein localization to microtubule cytoskeleton GO:0072698 1 0.038
regulation of multicellular organismal development GO:2000026 223 0.037
regulation of nucleocytoplasmic transport GO:0046822 2 0.037
regulation of nucleic acid templated transcription GO:1903506 213 0.037
blood vessel development GO:0001568 246 0.037
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.037
negative regulation of nuclear division GO:0051784 3 0.036
rna metabolic process GO:0016070 219 0.036
tube closure GO:0060606 1 0.036
regulation of cell cycle phase transition GO:1901987 8 0.035
developmental growth GO:0048589 166 0.035
cellular protein metabolic process GO:0044267 129 0.035
organelle fission GO:0048285 23 0.035
central nervous system development GO:0007417 387 0.035
regulation of primary metabolic process GO:0080090 311 0.035
establishment of localization GO:0051234 244 0.035
regulation of developmental process GO:0050793 247 0.034
regulation of chromosome segregation GO:0051983 1 0.034
meiotic chromosome segregation GO:0045132 3 0.034
regulation of cellular biosynthetic process GO:0031326 245 0.034
adult behavior GO:0030534 2 0.034
mitotic nuclear division GO:0007067 18 0.034
cytoskeleton organization GO:0007010 96 0.033
protein import into nucleus GO:0006606 3 0.033
sensory organ morphogenesis GO:0090596 200 0.033
cellular localization GO:0051641 97 0.033
sensory organ development GO:0007423 393 0.032
cellular biosynthetic process GO:0044249 286 0.032
intracellular signal transduction GO:0035556 85 0.032
multi organism process GO:0051704 134 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
locomotion GO:0040011 313 0.032
positive regulation of developmental process GO:0051094 50 0.031
regulation of protein complex disassembly GO:0043244 1 0.031
regulation of gene expression GO:0010468 265 0.031
protein targeting to nucleus GO:0044744 3 0.031
small gtpase mediated signal transduction GO:0007264 8 0.031
cellular ketone metabolic process GO:0042180 11 0.031
regulation of protein localization to nucleus GO:1900180 2 0.030
modification dependent protein catabolic process GO:0019941 3 0.030
regulation of cellular component organization GO:0051128 86 0.030
cell migration GO:0016477 237 0.030
regulation of cytoplasmic transport GO:1903649 4 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.029
negative regulation of cellular process GO:0048523 283 0.029
compound eye development GO:0048749 2 0.029
organelle assembly GO:0070925 110 0.029
positive regulation of cell division GO:0051781 2 0.028
neuron differentiation GO:0030182 353 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
protein complex biogenesis GO:0070271 30 0.028
response to stress GO:0006950 263 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
regulation of binding GO:0051098 3 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
regulation of embryonic development GO:0045995 47 0.027
regulation of protein transport GO:0051223 3 0.027
regulation of signal transduction GO:0009966 225 0.027
positive regulation of macromolecule metabolic process GO:0010604 93 0.026
cell growth GO:0016049 57 0.026
female meiotic division GO:0007143 2 0.026
protein metabolic process GO:0019538 183 0.026
oocyte development GO:0048599 14 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.025
regulation of cell communication GO:0010646 232 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.024
cell substrate adhesion GO:0031589 4 0.024
protein modification process GO:0036211 100 0.024
negative regulation of response to stimulus GO:0048585 104 0.023
regulation of intracellular signal transduction GO:1902531 57 0.023
positive regulation of cellular metabolic process GO:0031325 94 0.023
amine metabolic process GO:0009308 2 0.023
regulation of reproductive process GO:2000241 4 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
macromolecular complex disassembly GO:0032984 1 0.022
nucleic acid templated transcription GO:0097659 181 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
negative regulation of mitotic cell cycle GO:0045930 11 0.022
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
negative regulation of cell cycle GO:0045786 14 0.021
organic acid metabolic process GO:0006082 31 0.021
regulation of neurogenesis GO:0050767 87 0.021
regulation of inflammatory response GO:0050727 2 0.021
cellular response to oxygen levels GO:0071453 1 0.021
cytoskeleton dependent cytokinesis GO:0061640 3 0.021
cell projection organization GO:0030030 284 0.021
positive regulation of rna biosynthetic process GO:1902680 57 0.021
mitotic cytokinesis GO:0000281 3 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
regulation of transcription dna templated GO:0006355 213 0.021
mrna metabolic process GO:0016071 20 0.021
cellular response to stress GO:0033554 62 0.021
oocyte differentiation GO:0009994 14 0.020
peptidyl threonine phosphorylation GO:0018107 1 0.020
cellular amine metabolic process GO:0044106 2 0.020
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.020
male meiosis GO:0007140 2 0.020
cell morphogenesis GO:0000902 289 0.020
negative regulation of mitosis GO:0045839 3 0.020
sister chromatid segregation GO:0000819 6 0.020
establishment of endothelial barrier GO:0061028 3 0.020
mitochondrion organization GO:0007005 4 0.020
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.020
positive regulation of gene expression GO:0010628 71 0.020
regulation of protein depolymerization GO:1901879 1 0.020
generation of neurons GO:0048699 385 0.019
negative regulation of signal transduction GO:0009968 94 0.019
fertilization GO:0009566 3 0.019
protein localization to centrosome GO:0071539 1 0.019
regulation of cell cycle g2 m phase transition GO:1902749 4 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
protein complex disassembly GO:0043241 1 0.019
protein complex assembly GO:0006461 30 0.018
negative regulation of metabolic process GO:0009892 86 0.018
single organism localization GO:1902578 225 0.018
regulation of cellular protein metabolic process GO:0032268 52 0.018
negative regulation of signaling GO:0023057 96 0.018
death GO:0016265 121 0.018
meiosis ii GO:0007135 1 0.018
golgi organization GO:0007030 1 0.018
negative regulation of cell communication GO:0010648 96 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of programmed cell death GO:0043067 101 0.017
regulation of protein binding GO:0043393 3 0.017
organelle organization GO:0006996 227 0.017
female sex differentiation GO:0046660 4 0.017
protein acetylation GO:0006473 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
single organism transport GO:0044765 206 0.017
blood vessel morphogenesis GO:0048514 216 0.017
localization of cell GO:0051674 244 0.017
cell proliferation GO:0008283 80 0.017
negative regulation of protein transport GO:0051224 3 0.017
regulation of mitochondrion organization GO:0010821 1 0.016
nuclear envelope organization GO:0006998 2 0.016
signal transduction by p53 class mediator GO:0072331 13 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
cell part morphogenesis GO:0032990 246 0.016
cellular response to external stimulus GO:0071496 2 0.016
oxoacid metabolic process GO:0043436 31 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
protein polyubiquitination GO:0000209 4 0.016
negative regulation of intracellular signal transduction GO:1902532 22 0.015
phosphorylation GO:0016310 69 0.015
response to external stimulus GO:0009605 264 0.015
translation GO:0006412 5 0.015
cellular response to hypoxia GO:0071456 1 0.015
female gonad development GO:0008585 4 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
multicellular organism reproduction GO:0032504 35 0.015
retinal rod cell development GO:0046548 4 0.015
viral process GO:0016032 1 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
transcription dna templated GO:0006351 181 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
regulation of apoptotic process GO:0042981 98 0.014
regulation of mitotic cell cycle phase transition GO:1901990 8 0.014
neuron development GO:0048666 262 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
regulation of cellular component movement GO:0051270 55 0.014
mitotic sister chromatid segregation GO:0000070 6 0.014
protein localization GO:0008104 40 0.014
protein polymerization GO:0051258 4 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
negative regulation of cell cycle process GO:0010948 9 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
cellular component movement GO:0006928 335 0.014
organelle localization GO:0051640 49 0.014
negative regulation of cell death GO:0060548 60 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
intracellular mrna localization GO:0008298 1 0.014
growth GO:0040007 174 0.014
organelle fusion GO:0048284 3 0.014
response to hypoxia GO:0001666 25 0.014
macromolecular complex assembly GO:0065003 35 0.014
proteasomal protein catabolic process GO:0010498 2 0.013
convergent extension GO:0060026 118 0.013
negative regulation of kinase activity GO:0033673 4 0.013
embryonic heart tube development GO:0035050 133 0.013
spindle assembly involved in meiosis GO:0090306 1 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
reciprocal dna recombination GO:0035825 1 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
cell cycle arrest GO:0007050 1 0.013
response to alkaloid GO:0043279 2 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
head development GO:0060322 303 0.013
cell fate commitment GO:0045165 99 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
microtubule cytoskeleton organization GO:0000226 33 0.013
rna localization GO:0006403 4 0.013
negative regulation of protein kinase activity GO:0006469 4 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
positive regulation of rna metabolic process GO:0051254 59 0.012
axoneme assembly GO:0035082 9 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
angiogenesis GO:0001525 158 0.012
ras protein signal transduction GO:0007265 7 0.012
cell death GO:0008219 121 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
determination of left right symmetry GO:0007368 179 0.012
stem cell maintenance GO:0019827 4 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of organelle organization GO:0033043 29 0.012
regulation of metal ion transport GO:0010959 4 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
eye morphogenesis GO:0048592 144 0.012
regulation of cell proliferation GO:0042127 37 0.012
gtp catabolic process GO:0006184 2 0.012
multi organism cellular process GO:0044764 2 0.012
regulation of cell fate specification GO:0042659 20 0.012
regulation of synapse organization GO:0050807 3 0.011
atp catabolic process GO:0006200 4 0.011
macromolecule localization GO:0033036 54 0.011
positive regulation of signaling GO:0023056 56 0.011
lipid storage GO:0019915 1 0.011
rna biosynthetic process GO:0032774 181 0.011
cellular response to radiation GO:0071478 4 0.011
regulation of dna metabolic process GO:0051052 11 0.011
intracellular transport GO:0046907 32 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of cell shape GO:0008360 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of cell death GO:0010941 103 0.011
lateral inhibition GO:0046331 1 0.011
regulation of locomotion GO:0040012 55 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of cell adhesion GO:0030155 15 0.011
protein localization to cytoskeleton GO:0044380 1 0.011
apoptotic process GO:0006915 116 0.011
phagocytosis GO:0006909 3 0.011
cilium assembly GO:0042384 58 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
macromolecule modification GO:0043412 111 0.010
positive regulation of cytokine production GO:0001819 2 0.010
digestive system development GO:0055123 289 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
cytokinetic process GO:0032506 2 0.010
cell adhesion GO:0007155 40 0.010
hemopoiesis GO:0030097 183 0.010
eye development GO:0001654 277 0.010
response to transition metal nanoparticle GO:1990267 28 0.010
response to external biotic stimulus GO:0043207 97 0.010
regulation of gtpase activity GO:0043087 2 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010

arhgap11a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
physical disorder DOID:0080015 0 0.015
congenital nervous system abnormality DOID:2490 0 0.015