Danio rerio

68 known processes

arrb2b

arrestin, beta 2b

(Aliases: arrb2,zgc:64007,MGC64007)

arrb2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound metabolic process GO:0034641 290 0.417
Human
cellular biosynthetic process GO:0044249 286 0.388
Human
vasculature development GO:0001944 278 0.360
heterocycle biosynthetic process GO:0018130 215 0.343
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.342
Human
organic cyclic compound metabolic process GO:1901360 301 0.241
Human
locomotion GO:0040011 313 0.208
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.208
Human
organic acid metabolic process GO:0006082 31 0.203
muscle structure development GO:0061061 196 0.190
regulation of gene expression GO:0010468 265 0.189
Human Fly
regulation of cellular metabolic process GO:0031323 320 0.187
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.182
Human
transport GO:0006810 220 0.166
Human
aromatic compound biosynthetic process GO:0019438 217 0.161
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.160
Human
blood vessel morphogenesis GO:0048514 216 0.160
response to chemical GO:0042221 320 0.155
meiotic nuclear division GO:0007126 4 0.151
single organism metabolic process GO:0044710 217 0.143
Human
signal transduction GO:0007165 455 0.142
establishment of localization GO:0051234 244 0.139
Human
muscle cell differentiation GO:0042692 139 0.138
regulation of developmental process GO:0050793 247 0.134
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.131
Human
phagocytosis GO:0006909 3 0.129
erk1 and erk2 cascade GO:0070371 4 0.126
Human
regulation of metabolic process GO:0019222 359 0.125
regulation of macromolecule biosynthetic process GO:0010556 225 0.125
Human
regulation of transcription dna templated GO:0006355 213 0.118
Human
single organism localization GO:1902578 225 0.117
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.116
Human
organic substance biosynthetic process GO:1901576 289 0.114
Human
nucleic acid metabolic process GO:0090304 244 0.110
Human
heart development GO:0007507 313 0.109
oxoacid metabolic process GO:0043436 31 0.109
rna metabolic process GO:0016070 219 0.108
Human
positive regulation of transport GO:0051050 2 0.105
Human
regulation of primary metabolic process GO:0080090 311 0.103
Human Mouse Fly
biosynthetic process GO:0009058 294 0.102
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.100
Human
blood vessel development GO:0001568 246 0.100
larval development GO:0002164 2 0.100
Fly
cortical cytoskeleton organization GO:0030865 1 0.098
pole plasm assembly GO:0007315 4 0.095
regulation of wound healing GO:0061041 2 0.094
enzyme linked receptor protein signaling pathway GO:0007167 106 0.093
Human
regulation of macromolecule metabolic process GO:0060255 317 0.091
mononuclear cell proliferation GO:0032943 1 0.091
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.088
nuclear transport GO:0051169 4 0.088
small molecule metabolic process GO:0044281 77 0.088
nucleobase containing compound metabolic process GO:0006139 274 0.087
Human
transcription dna templated GO:0006351 181 0.087
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.087
regulation of intracellular protein transport GO:0033157 3 0.086
positive regulation of macromolecule metabolic process GO:0010604 93 0.085
Human Fly
cellular ketone metabolic process GO:0042180 11 0.083
negative regulation of biological process GO:0048519 304 0.082
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.081
regulation of establishment of protein localization GO:0070201 4 0.081
aging GO:0007568 2 0.080
stem cell development GO:0048864 82 0.079
stem cell maintenance GO:0019827 4 0.078
peptidyl serine phosphorylation GO:0018105 1 0.078
germ line stem cell maintenance GO:0030718 2 0.076
nitrogen compound metabolic process GO:0006807 319 0.076
Human
positive regulation of cell activation GO:0050867 1 0.076
guanosine containing compound metabolic process GO:1901068 4 0.075
cellular aromatic compound metabolic process GO:0006725 295 0.075
Human
macromolecule biosynthetic process GO:0009059 227 0.075
Human
neurotransmitter transport GO:0006836 2 0.073
peptidyl serine modification GO:0018209 2 0.072
cellular response to chemical stimulus GO:0070887 157 0.072
adherens junction organization GO:0034332 4 0.070
positive regulation of cellular metabolic process GO:0031325 94 0.070
Human Fly
defense response GO:0006952 47 0.067
Human Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.067
positive regulation of gene expression GO:0010628 71 0.067
rna biosynthetic process GO:0032774 181 0.066
Human
positive regulation of biosynthetic process GO:0009891 68 0.063
amine metabolic process GO:0009308 2 0.062
protein localization to nucleus GO:0034504 3 0.062
cellular protein metabolic process GO:0044267 129 0.062
Human Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.061
guanosine containing compound catabolic process GO:1901069 2 0.061
protein import into nucleus GO:0006606 3 0.061
cytoplasm organization GO:0007028 4 0.061
nucleocytoplasmic transport GO:0006913 4 0.060
regulation of protein transport GO:0051223 3 0.060
nuclear import GO:0051170 3 0.060
single organism organelle organization GO:1902589 199 0.060
carboxylic acid metabolic process GO:0019752 22 0.060
heterocycle metabolic process GO:0046483 290 0.059
Human
immune system development GO:0002520 191 0.059
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.058
Human
oocyte anterior posterior axis specification GO:0007314 4 0.058
single organism nuclear import GO:1902593 3 0.058
cellular amine metabolic process GO:0044106 2 0.056
regulation of biosynthetic process GO:0009889 250 0.056
Human
response to monosaccharide GO:0034284 3 0.055
single organism transport GO:0044765 206 0.055
Human
protein import GO:0017038 3 0.054
establishment of protein localization to organelle GO:0072594 4 0.054
positive regulation of metabolic process GO:0009893 108 0.053
Human Fly
positive regulation of cellular process GO:0048522 201 0.053
Human Mouse Fly
digestive tract development GO:0048565 265 0.053
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.053
regulation of reactive oxygen species metabolic process GO:2000377 2 0.053
neuroblast proliferation GO:0007405 2 0.052
stem cell proliferation GO:0072089 4 0.052
protein targeting to nucleus GO:0044744 3 0.051
regulation of biological quality GO:0065008 263 0.051
Fly
positive regulation of cell cycle GO:0045787 3 0.051
regulation of erk1 and erk2 cascade GO:0070372 4 0.051
Human
cell substrate adhesion GO:0031589 4 0.050
cellular component movement GO:0006928 335 0.050
cell cycle GO:0007049 93 0.050
angiogenesis GO:0001525 158 0.050
cellular macromolecule metabolic process GO:0044260 391 0.050
segmentation GO:0035282 97 0.049
positive regulation of biological process GO:0048518 253 0.049
Human Mouse Worm Fly
cell surface receptor signaling pathway GO:0007166 325 0.049
regulation of cytoplasmic transport GO:1903649 4 0.049
protein localization to plasma membrane GO:0072659 1 0.048
cellular component disassembly GO:0022411 1 0.047
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.047
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.047
regulation of protein complex assembly GO:0043254 3 0.047
immune response GO:0006955 28 0.047
Human
ion transmembrane transport GO:0034220 91 0.047
nucleic acid templated transcription GO:0097659 181 0.046
Human
rna localization GO:0006403 4 0.046
exocytosis GO:0006887 1 0.046
neuron neuron synaptic transmission GO:0007270 1 0.045
Mouse
regulation of binding GO:0051098 3 0.045
protein metabolic process GO:0019538 183 0.044
Human Mouse Fly
regulation of nucleoside metabolic process GO:0009118 2 0.044
muscle tissue development GO:0060537 110 0.044
positive regulation of wound healing GO:0090303 1 0.044
regulation of rna metabolic process GO:0051252 224 0.044
Human
internal peptidyl lysine acetylation GO:0018393 2 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.044
response to carbohydrate GO:0009743 3 0.043
gene expression GO:0010467 252 0.043
Human Fly
cognition GO:0050890 1 0.043
neurotransmitter secretion GO:0007269 2 0.043
gtp metabolic process GO:0046039 4 0.042
macromolecule modification GO:0043412 111 0.042
Human Mouse Fly
transmembrane transport GO:0055085 120 0.042
multi organism process GO:0051704 134 0.042
multicellular organism growth GO:0035264 4 0.041
regulation of cell activation GO:0050865 1 0.041
regulation of protein targeting GO:1903533 2 0.040
meiotic cell cycle process GO:1903046 3 0.040
reactive oxygen species metabolic process GO:0072593 6 0.040
regulation of multicellular organismal development GO:2000026 223 0.040
Fly
positive regulation of catabolic process GO:0009896 4 0.039
regulation of stem cell proliferation GO:0072091 2 0.039
anterior posterior pattern specification GO:0009952 152 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.039
specification of symmetry GO:0009799 204 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.038
phosphate containing compound metabolic process GO:0006796 108 0.038
Human Mouse Fly
cell proliferation GO:0008283 80 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.036
maternal determination of anterior posterior axis embryo GO:0008358 4 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.036
mitotic cell cycle GO:0000278 64 0.036
regulation of protein import into nucleus GO:0042306 2 0.036
synaptic vesicle localization GO:0097479 1 0.035
leukocyte activation GO:0045321 12 0.035
regulation of nucleic acid templated transcription GO:1903506 213 0.035
Human
leukocyte proliferation GO:0070661 1 0.035
growth GO:0040007 174 0.035
Worm
generation of neurons GO:0048699 385 0.034
regionalization GO:0003002 274 0.034
cell cycle g1 s phase transition GO:0044843 1 0.034
protein polymerization GO:0051258 4 0.034
cellular lipid metabolic process GO:0044255 36 0.033
tube morphogenesis GO:0035239 349 0.033
Fly
actin filament based process GO:0030029 64 0.033
negative regulation of protein phosphorylation GO:0001933 4 0.032
Fly
striated muscle tissue development GO:0014706 110 0.032
erythrocyte homeostasis GO:0034101 55 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.032
Human
mitotic cell cycle process GO:1903047 48 0.031
cellular component assembly GO:0022607 170 0.031
response to glucose GO:0009749 3 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
Human
response to other organism GO:0051707 97 0.031
regulation of reproductive process GO:2000241 4 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.031
meiotic chromosome segregation GO:0045132 3 0.030
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
hormone transport GO:0009914 2 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.030
g1 s transition of mitotic cell cycle GO:0000082 1 0.030
regulation of cell differentiation GO:0045595 142 0.030
Fly
regulation of protein polymerization GO:0032271 2 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
gtp catabolic process GO:0006184 2 0.029
morphogenesis of an epithelium GO:0002009 333 0.029
stem cell division GO:0017145 1 0.029
actin polymerization or depolymerization GO:0008154 2 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
Human
immune system process GO:0002376 241 0.029
Human Mouse Fly
cellular protein complex assembly GO:0043623 19 0.028
response to hexose GO:0009746 3 0.028
erythrocyte differentiation GO:0030218 54 0.028
positive regulation of nucleic acid templated transcription GO:1903508 57 0.028
organelle assembly GO:0070925 110 0.028
protein complex disassembly GO:0043241 1 0.028
negative regulation of mapk cascade GO:0043409 4 0.028
establishment of endothelial barrier GO:0061028 3 0.028
lamellipodium organization GO:0097581 1 0.028
response to external stimulus GO:0009605 264 0.028
intracellular mrna localization GO:0008298 1 0.027
synaptic vesicle transport GO:0048489 1 0.027
regulation of neural precursor cell proliferation GO:2000177 3 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
regulation of defense response GO:0031347 14 0.027
Human Mouse Fly
regulation of nervous system development GO:0051960 90 0.027
regulation of oocyte development GO:0060281 3 0.027
protein depolymerization GO:0051261 1 0.026
positive regulation of rna metabolic process GO:0051254 59 0.026
cellular protein modification process GO:0006464 100 0.026
Human Mouse Fly
protein modification process GO:0036211 100 0.026
Human Mouse Fly
positive regulation of gtp catabolic process GO:0033126 1 0.026
embryonic hemopoiesis GO:0035162 53 0.026
cortical actin cytoskeleton organization GO:0030866 1 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
determination of left right symmetry GO:0007368 179 0.026
cellular carbohydrate metabolic process GO:0044262 4 0.025
macromolecular complex disassembly GO:0032984 1 0.025
positive regulation of map kinase activity GO:0043406 3 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.025
digestive system development GO:0055123 289 0.025
Fly
negative regulation of cellular process GO:0048523 283 0.025
Human Mouse Fly
protein localization GO:0008104 40 0.025
response to bacterium GO:0009617 58 0.025
determination of bilateral symmetry GO:0009855 204 0.025
metal ion transport GO:0030001 58 0.024
single organism membrane organization GO:0044802 20 0.024
homeostasis of number of cells GO:0048872 62 0.024
blood circulation GO:0008015 87 0.024
mesenchyme development GO:0060485 127 0.024
protein dephosphorylation GO:0006470 3 0.024
negative regulation of cell communication GO:0010648 96 0.024
Human Mouse Fly
regulation of myotube differentiation GO:0010830 2 0.024
cytoskeleton organization GO:0007010 96 0.024
positive regulation of rna biosynthetic process GO:1902680 57 0.023
positive regulation of cell adhesion GO:0045785 1 0.023
negative regulation of developmental process GO:0051093 65 0.023
Fly
neuron development GO:0048666 262 0.023
wound healing GO:0042060 90 0.023
regulation of signal transduction GO:0009966 225 0.023
stem cell differentiation GO:0048863 117 0.023
regulation of cellular component organization GO:0051128 86 0.023
Human
positive regulation of secretion GO:0051047 1 0.023
lipid metabolic process GO:0006629 52 0.022
nuclear export GO:0051168 1 0.022
regulation of circadian rhythm GO:0042752 4 0.022
hemopoiesis GO:0030097 183 0.022
Fly
negative regulation of cell differentiation GO:0045596 46 0.022
Fly
organelle organization GO:0006996 227 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
Human
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
positive regulation of transcription dna templated GO:0045893 57 0.022
regulation of cell shape GO:0008360 1 0.022
muscle organ development GO:0007517 101 0.022
establishment of organelle localization GO:0051656 45 0.022
chemotaxis GO:0006935 104 0.021
striated muscle cell differentiation GO:0051146 129 0.021
cellular component biogenesis GO:0044085 178 0.021
positive regulation of cell death GO:0010942 29 0.021
lymphocyte proliferation GO:0046651 1 0.021
cell projection organization GO:0030030 284 0.021
negative regulation of neural precursor cell proliferation GO:2000178 1 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
coagulation GO:0050817 13 0.020
cell morphogenesis GO:0000902 289 0.020
regulation of sodium ion transport GO:0002028 2 0.020
synaptic transmission GO:0007268 35 0.020
Mouse
neuron differentiation GO:0030182 353 0.020
cellular response to organic substance GO:0071310 105 0.020
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.020
Human
regulation of immune system process GO:0002682 34 0.020
Human Mouse Fly
phosphorylation GO:0016310 69 0.020
Human Mouse Fly
lamellipodium assembly GO:0030032 1 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
regulation of localization GO:0032879 104 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
golgi vesicle transport GO:0048193 3 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
localization of cell GO:0051674 244 0.019
cytokinesis GO:0000910 3 0.019
actin cytoskeleton organization GO:0030036 63 0.019
sleep GO:0030431 1 0.019
regulation of body fluid levels GO:0050878 16 0.019
actin filament polymerization GO:0030041 2 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.019
Human
regulation of exocytosis GO:0017157 1 0.019
cellular localization GO:0051641 97 0.019
positive regulation of muscle cell differentiation GO:0051149 1 0.019
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.018
organophosphate biosynthetic process GO:0090407 23 0.018
system process GO:0003008 185 0.018
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.018
Mouse Fly
regulation of cytokine production GO:0001817 3 0.018
Mouse
actomyosin structure organization GO:0031032 53 0.018
peptide transport GO:0015833 1 0.018
positive regulation of protein kinase b signaling GO:0051897 1 0.018
Mouse
blood coagulation GO:0007596 12 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
long chain fatty acid metabolic process GO:0001676 1 0.018
striated muscle cell development GO:0055002 108 0.018
regulation of protein binding GO:0043393 3 0.018
membrane organization GO:0061024 21 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
liver development GO:0001889 96 0.018
peptidyl threonine phosphorylation GO:0018107 1 0.017
positive regulation of cell division GO:0051781 2 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
response to external biotic stimulus GO:0043207 97 0.017
innate immune response GO:0045087 13 0.017
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.017
Fly
negative regulation of kinase activity GO:0033673 4 0.017
Fly
membrane lipid biosynthetic process GO:0046467 2 0.017
regulation of neurotransmitter transport GO:0051588 1 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
negative regulation of cell death GO:0060548 60 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
regulation of phosphorylation GO:0042325 26 0.017
Human Mouse Fly
neural precursor cell proliferation GO:0061351 20 0.017
regulation of signaling GO:0023051 235 0.017
cation transport GO:0006812 81 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
carbohydrate homeostasis GO:0033500 1 0.017
regulation of response to stress GO:0080134 36 0.016
Human Mouse Fly
peptidyl threonine modification GO:0018210 1 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
Human
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
Human Fly
outflow tract morphogenesis GO:0003151 1 0.016
somatic muscle development GO:0007525 4 0.016
homeostatic process GO:0042592 142 0.016
head development GO:0060322 303 0.016
positive regulation of cytokine production GO:0001819 2 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
somite development GO:0061053 96 0.016
regulation of gtpase activity GO:0043087 2 0.016
response to drug GO:0042493 3 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.015
behavior GO:0007610 74 0.015
regulation of blood pressure GO:0008217 1 0.015
response to wounding GO:0009611 116 0.015
Fly
digestive tract morphogenesis GO:0048546 231 0.015
Fly
embryonic axis specification GO:0000578 12 0.015
maintenance of location GO:0051235 4 0.015
developmental growth GO:0048589 166 0.015
cell substrate junction assembly GO:0007044 2 0.015
regulation of dna replication GO:0006275 3 0.015
pancreas development GO:0031016 84 0.015
cellular response to xenobiotic stimulus GO:0071466 35 0.015
b cell activation GO:0042113 2 0.015
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
response to organic substance GO:0010033 153 0.015
Human
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.015
cell part morphogenesis GO:0032990 246 0.015
compound eye development GO:0048749 2 0.015
myeloid cell homeostasis GO:0002262 56 0.015
establishment of localization in cell GO:0051649 77 0.015
single organism cellular localization GO:1902580 46 0.014
regulation of cell projection assembly GO:0060491 4 0.014
regulation of inflammatory response GO:0050727 2 0.014
Fly
positive regulation of defense response GO:0031349 9 0.014
Mouse
vesicle localization GO:0051648 27 0.014
renal absorption GO:0070293 1 0.014
mitochondrion organization GO:0007005 4 0.014
endomembrane system organization GO:0010256 13 0.014
regulation of cell development GO:0060284 100 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
Human
negative regulation of cytokine production GO:0001818 1 0.014
Mouse
regulation of metal ion transport GO:0010959 4 0.014
cell junction organization GO:0034330 11 0.014
endothelial cell differentiation GO:0045446 20 0.014
multi organism reproductive process GO:0044703 36 0.014
organelle localization GO:0051640 49 0.014
negative regulation of signaling GO:0023057 96 0.014
Human Mouse Fly
morphogenesis of an epithelial sheet GO:0002011 49 0.014
macromolecular complex assembly GO:0065003 35 0.014
organelle fission GO:0048285 23 0.014
protein localization to membrane GO:0072657 9 0.014
regulation of protein localization to plasma membrane GO:1903076 1 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
phagocytosis engulfment GO:0006911 1 0.014
myeloid leukocyte migration GO:0097529 12 0.014
cell death GO:0008219 121 0.014
organic substance transport GO:0071702 58 0.014
trabecula morphogenesis GO:0061383 2 0.014
response to growth factor GO:0070848 39 0.013
Human
regulation of carbohydrate metabolic process GO:0006109 4 0.013
regulation of muscle contraction GO:0006937 3 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
Human Mouse Fly
cation transmembrane transport GO:0098655 65 0.013
phagosome maturation GO:0090382 1 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
Fly
regulation of receptor activity GO:0010469 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
Human Mouse Fly
single organism membrane fusion GO:0044801 2 0.013
protein acylation GO:0043543 3 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
negative regulation of metabolic process GO:0009892 86 0.013
Human Fly
cellular response to hypoxia GO:0071456 1 0.013
antimicrobial humoral response GO:0019730 2 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.012
positive regulation of cell substrate adhesion GO:0010811 1 0.012
positive regulation of cellular protein metabolic process GO:0032270 22 0.012
Human Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
death GO:0016265 121 0.012
regulation of cell communication GO:0010646 232 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
regulation of transferase activity GO:0051338 16 0.012
Fly
ion transport GO:0006811 114 0.012
immune effector process GO:0002252 23 0.012
Human
calcium mediated signaling GO:0019722 2 0.012
cell projection morphogenesis GO:0048858 244 0.012
calcium ion dependent exocytosis GO:0017156 1 0.012
single organism biosynthetic process GO:0044711 71 0.012
macromolecule localization GO:0033036 54 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
muscle cell development GO:0055001 115 0.012
cell migration GO:0016477 237 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
regulation of locomotion GO:0040012 55 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
organelle fusion GO:0048284 3 0.012
regulation of endocytosis GO:0030100 7 0.012
Human
regulation of cell cycle GO:0051726 52 0.012
hemostasis GO:0007599 13 0.012
central nervous system development GO:0007417 387 0.012
neuron projection development GO:0031175 180 0.012
microtubule based process GO:0007017 60 0.012
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.012
leukocyte chemotaxis GO:0030595 12 0.012
regulation of cell proliferation GO:0042127 37 0.012
nuclear division GO:0000280 23 0.012
regulation of multicellular organismal process GO:0051239 277 0.011
Mouse Fly
chordate embryonic development GO:0043009 271 0.011
circulatory system process GO:0003013 87 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
embryonic organ development GO:0048568 381 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
cellular protein complex disassembly GO:0043624 1 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
response to nutrient GO:0007584 3 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
Human
regulation of protein metabolic process GO:0051246 56 0.011
Human Mouse Fly
internal protein amino acid acetylation GO:0006475 2 0.011
negative regulation of reproductive process GO:2000242 3 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
regulation of calcium ion dependent exocytosis GO:0017158 1 0.011
peptidyl amino acid modification GO:0018193 16 0.011
Fly
cell activation GO:0001775 16 0.011
regulation of dendrite development GO:0050773 3 0.011
intracellular signal transduction GO:0035556 85 0.011
Human Mouse
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
endosomal transport GO:0016197 2 0.011
anterior posterior axis specification GO:0009948 20 0.011
organophosphate metabolic process GO:0019637 37 0.011
activation of mapk activity GO:0000187 3 0.011
response to stress GO:0006950 263 0.011
Human Fly
negative regulation of programmed cell death GO:0043069 58 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
regulation of establishment of planar polarity GO:0090175 4 0.011
cellular response to nutrient levels GO:0031669 2 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011

arrb2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
disease of cellular proliferation DOID:14566 0 0.027
cancer DOID:162 0 0.021
musculoskeletal system disease DOID:17 0 0.018
cardiovascular system disease DOID:1287 0 0.018
organ system cancer DOID:0050686 0 0.014
nervous system disease DOID:863 0 0.013
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013
disease of metabolism DOID:0014667 0 0.012
gastrointestinal system cancer DOID:3119 0 0.011