Danio rerio

40 known processes

arx

aristaless related homeobox

(Aliases: phox2a)

arx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.954
forebrain neuron development GO:0021884 7 0.936
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.889
Zebrafish Mouse
head development GO:0060322 303 0.888
biosynthetic process GO:0009058 294 0.864
Zebrafish Mouse
diencephalon development GO:0021536 58 0.861
cellular biosynthetic process GO:0044249 286 0.818
Zebrafish Mouse
locomotion GO:0040011 313 0.790
Mouse Worm
axonogenesis GO:0007409 152 0.787
Mouse
generation of neurons GO:0048699 385 0.785
central nervous system neuron differentiation GO:0021953 74 0.784
Mouse
regulation of biosynthetic process GO:0009889 250 0.776
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.774
Zebrafish Mouse
glial cell migration GO:0008347 3 0.760
response to chemical GO:0042221 320 0.756
Mouse
neuron projection development GO:0031175 180 0.745
Mouse
axon guidance GO:0007411 86 0.722
Mouse
brain development GO:0007420 293 0.705
nitrogen compound metabolic process GO:0006807 319 0.682
Zebrafish Mouse
nucleic acid templated transcription GO:0097659 181 0.672
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.664
cellular component movement GO:0006928 335 0.664
Mouse Worm
regulation of mechanoreceptor differentiation GO:0045631 1 0.642
cell projection organization GO:0030030 284 0.628
Mouse
organic substance biosynthetic process GO:1901576 289 0.623
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 274 0.623
rna biosynthetic process GO:0032774 181 0.595
Zebrafish Mouse
rna metabolic process GO:0016070 219 0.585
Zebrafish Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.583
Zebrafish Mouse
cell fate specification GO:0001708 68 0.581
Zebrafish Worm
heart development GO:0007507 313 0.578
regulation of cellular biosynthetic process GO:0031326 245 0.567
Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 217 0.563
Zebrafish Mouse
cell proliferation in forebrain GO:0021846 3 0.530
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.522
Zebrafish Mouse
heterocycle metabolic process GO:0046483 290 0.520
Zebrafish Mouse
forebrain development GO:0030900 96 0.510
neuron projection morphogenesis GO:0048812 161 0.505
Mouse
forebrain generation of neurons GO:0021872 14 0.499
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.483
Zebrafish Mouse
central nervous system neuron axonogenesis GO:0021955 18 0.483
negative regulation of axon guidance GO:1902668 1 0.410
embryonic organ development GO:0048568 381 0.407
transcription dna templated GO:0006351 181 0.405
Zebrafish Mouse
stem cell differentiation GO:0048863 117 0.389
odontogenesis of dentin containing tooth GO:0042475 1 0.362
cellular macromolecule metabolic process GO:0044260 391 0.359
Zebrafish Mouse
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.349
cell motility GO:0048870 244 0.348
Mouse Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.339
Zebrafish Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.335
Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.335
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.304
Zebrafish Mouse
central nervous system projection neuron axonogenesis GO:0021952 15 0.298
glial cell fate specification GO:0021780 4 0.282
forebrain neuron differentiation GO:0021879 14 0.281
Mouse
regulation of primary metabolic process GO:0080090 311 0.280
Zebrafish Mouse
astrocyte differentiation GO:0048708 1 0.275
regulation of inner ear receptor cell differentiation GO:2000980 1 0.271
negative regulation of biosynthetic process GO:0009890 55 0.266
Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.260
Zebrafish Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.256
Mouse
cell differentiation in spinal cord GO:0021515 40 0.254
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.251
Mouse
regulation of metabolic process GO:0019222 359 0.247
Zebrafish Mouse
limbic system development GO:0021761 16 0.240
endocrine pancreas development GO:0031018 27 0.238
axon development GO:0061564 166 0.237
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.228
Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.220
Zebrafish Mouse
organic cyclic compound metabolic process GO:1901360 301 0.210
Zebrafish Mouse
cell part morphogenesis GO:0032990 246 0.209
Mouse
regulation of glial cell differentiation GO:0045685 4 0.207
central nervous system neuron development GO:0021954 29 0.206
Mouse
neuron development GO:0048666 262 0.204
regulation of rna biosynthetic process GO:2001141 213 0.199
Zebrafish Mouse
oligodendrocyte cell fate specification GO:0021778 4 0.196
positive regulation of neuron migration GO:2001224 2 0.194
neuron fate specification GO:0048665 20 0.193
regulation of rna metabolic process GO:0051252 224 0.191
Zebrafish Mouse
ventral spinal cord development GO:0021517 35 0.185
localization of cell GO:0051674 244 0.182
Mouse Worm
neuron fate commitment GO:0048663 26 0.179
negative regulation of nervous system development GO:0051961 22 0.173
negative regulation of biological process GO:0048519 304 0.173
Zebrafish Mouse
cell projection morphogenesis GO:0048858 244 0.173
Mouse
cardiocyte differentiation GO:0035051 44 0.168
positive regulation of biosynthetic process GO:0009891 68 0.163
regulation of transcription dna templated GO:0006355 213 0.162
Zebrafish Mouse
positive regulation of nervous system development GO:0051962 25 0.158
cellular component assembly involved in morphogenesis GO:0010927 107 0.158
regulation of cellular metabolic process GO:0031323 320 0.152
Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.150
Zebrafish Mouse
regionalization GO:0003002 274 0.148
positive regulation of cellular biosynthetic process GO:0031328 68 0.146
neuron projection guidance GO:0097485 86 0.145
Mouse
stem cell proliferation GO:0072089 4 0.143
endocrine system development GO:0035270 65 0.141
olfactory bulb development GO:0021772 4 0.138
Mouse
inner ear development GO:0048839 126 0.135
auditory receptor cell fate commitment GO:0009912 4 0.132
pituitary gland development GO:0021983 16 0.131
negative regulation of neural precursor cell proliferation GO:2000178 1 0.128
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.128
Zebrafish Mouse
single organism behavior GO:0044708 24 0.128
forebrain regionalization GO:0021871 4 0.126
spinal cord development GO:0021510 46 0.126
positive regulation of rna metabolic process GO:0051254 59 0.124
response to external stimulus GO:0009605 264 0.123
Mouse
anterior commissure morphogenesis GO:0021960 3 0.123
ventral midline development GO:0007418 13 0.121
muscle structure development GO:0061061 196 0.120
dendrite guidance GO:0070983 0 0.119
neuroblast differentiation GO:0014016 1 0.119
skeletal muscle organ development GO:0060538 78 0.119
oligodendrocyte differentiation GO:0048709 23 0.118
regulation of cell morphogenesis GO:0022604 42 0.116
gene expression GO:0010467 252 0.116
Zebrafish Mouse
adenohypophysis development GO:0021984 15 0.115
heterocycle biosynthetic process GO:0018130 215 0.115
Zebrafish Mouse
regulation of stem cell proliferation GO:0072091 2 0.114
cell migration GO:0016477 237 0.113
Mouse Worm
positive regulation of nucleic acid templated transcription GO:1903508 57 0.112
olfactory bulb axon guidance GO:0071678 3 0.110
negative regulation of response to stimulus GO:0048585 104 0.107
mechanoreceptor differentiation GO:0042490 37 0.107
embryonic heart tube development GO:0035050 133 0.106
epithelial tube morphogenesis GO:0060562 148 0.105
neuron fate determination GO:0048664 2 0.105
negative regulation of developmental process GO:0051093 65 0.103
Zebrafish
anterior posterior axon guidance GO:0033564 5 0.103
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.100
regulation of oligodendrocyte differentiation GO:0048713 1 0.098
negative regulation of neurogenesis GO:0050768 20 0.096
positive regulation of transcription dna templated GO:0045893 57 0.093
ectodermal placode formation GO:0060788 26 0.093
negative regulation of gliogenesis GO:0014014 1 0.093
establishment of localization GO:0051234 244 0.093
adult behavior GO:0030534 2 0.092
fin development GO:0033333 77 0.092
negative regulation of cell differentiation GO:0045596 46 0.089
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.087
striated muscle cell differentiation GO:0051146 129 0.086
ear development GO:0043583 127 0.085
pharyngeal muscle development GO:0043282 4 0.082
response to nicotine GO:0035094 2 0.082
cell proliferation GO:0008283 80 0.081
Mouse
taxis GO:0042330 109 0.081
Mouse
neural tube patterning GO:0021532 33 0.081
organ formation GO:0048645 17 0.079
determination of bilateral symmetry GO:0009855 204 0.078
positive regulation of cellular component biogenesis GO:0044089 3 0.078
positive regulation of gene expression GO:0010628 71 0.077
morphogenesis of embryonic epithelium GO:0016331 30 0.077
floor plate morphogenesis GO:0033505 12 0.077
striated muscle cell development GO:0055002 108 0.076
positive regulation of stem cell proliferation GO:2000648 1 0.074
regulation of axon guidance GO:1902667 8 0.073
cardiac chamber formation GO:0003207 4 0.072
kidney development GO:0001822 92 0.072
segmentation GO:0035282 97 0.072
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.072
regulation of mesenchymal cell proliferation GO:0010464 1 0.072
cell morphogenesis GO:0000902 289 0.069
Mouse
cellular component morphogenesis GO:0032989 336 0.068
Mouse
inner ear receptor cell fate commitment GO:0060120 4 0.068
regulation of developmental process GO:0050793 247 0.068
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.068
Zebrafish Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.066
positive regulation of cell cycle GO:0045787 3 0.066
cell fate commitment GO:0045165 99 0.066
Zebrafish Mouse Worm
thalamus development GO:0021794 6 0.066
cellular response to chemical stimulus GO:0070887 157 0.065
neuron recognition GO:0008038 18 0.063
regulation of gene expression GO:0010468 265 0.062
Zebrafish Mouse
appendage morphogenesis GO:0035107 56 0.062
response to wounding GO:0009611 116 0.061
reproductive process GO:0022414 40 0.060
Worm
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254 5 0.060
regulation of nitrogen compound metabolic process GO:0051171 251 0.060
Zebrafish Mouse
brain segmentation GO:0035284 6 0.059
locomotory behavior GO:0007626 34 0.056
negative regulation of cell communication GO:0010648 96 0.056
positive regulation of neurogenesis GO:0050769 24 0.055
gastrulation GO:0007369 208 0.054
Zebrafish
specification of symmetry GO:0009799 204 0.054
regulation of axonogenesis GO:0050770 32 0.054
muscle organ development GO:0007517 101 0.053
striated muscle tissue development GO:0014706 110 0.051
regulation of axon extension GO:0030516 24 0.051
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.051
Zebrafish Mouse
transport GO:0006810 220 0.051
chemotaxis GO:0006935 104 0.050
Mouse
midbrain hindbrain boundary development GO:0030917 23 0.050
cardioblast differentiation GO:0010002 9 0.049
inner ear receptor cell differentiation GO:0060113 29 0.049
heart formation GO:0060914 13 0.049
telencephalon development GO:0021537 14 0.048
Mouse
forebrain cell migration GO:0021885 1 0.047
Mouse
intracellular estrogen receptor signaling pathway GO:0030520 3 0.047
positive regulation of developmental process GO:0051094 50 0.047
Mouse
response to stress GO:0006950 263 0.047
negative regulation of gene expression GO:0010629 65 0.047
Zebrafish Mouse
cardioblast migration GO:0003260 7 0.047
tissue regeneration GO:0042246 74 0.047
negative regulation of transcription dna templated GO:0045892 45 0.047
Zebrafish Mouse
auditory receptor cell fate determination GO:0042668 2 0.045
gliogenesis GO:0042063 45 0.045
chordate embryonic development GO:0043009 271 0.044
regulation of macromolecule biosynthetic process GO:0010556 225 0.044
Zebrafish Mouse
spinal cord motor neuron differentiation GO:0021522 26 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.044
closure of optic fissure GO:0061386 6 0.043
regulation of multicellular organismal development GO:2000026 223 0.043
Zebrafish
stem cell maintenance GO:0019827 4 0.043
trigeminal nerve development GO:0021559 3 0.043
multicellular organism growth GO:0035264 4 0.043
axon extension GO:0048675 45 0.042
morphogenesis of an epithelium GO:0002009 333 0.042
notochord development GO:0030903 54 0.042
glial cell fate commitment GO:0021781 6 0.042
regulation of multicellular organism growth GO:0040014 4 0.042
cell proliferation in hindbrain GO:0021534 4 0.041
appendage development GO:0048736 80 0.041
regulation of cell cycle GO:0051726 52 0.040
negative regulation of cell development GO:0010721 26 0.040
mesenchymal cell proliferation GO:0010463 1 0.040
forebrain anterior posterior pattern specification GO:0021797 3 0.040
neuron projection extension GO:1990138 45 0.040
negative regulation of cellular biosynthetic process GO:0031327 55 0.039
Zebrafish Mouse
cell fate specification involved in pattern specification GO:0060573 3 0.039
negative regulation of macromolecule metabolic process GO:0010605 76 0.038
Zebrafish Mouse
formation of primary germ layer GO:0001704 62 0.036
Zebrafish
neural tube development GO:0021915 62 0.036
gland development GO:0048732 143 0.036
pancreas development GO:0031016 84 0.036
positive regulation of biological process GO:0048518 253 0.035
Mouse
cardiac atrium morphogenesis GO:0003209 2 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.035
Zebrafish Mouse
embryonic camera type eye morphogenesis GO:0048596 19 0.035
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.035
regulation of growth GO:0040008 42 0.035
Mouse
response to amphetamine GO:0001975 1 0.034
ventral spinal cord interneuron specification GO:0021521 3 0.034
endodermal cell fate determination GO:0007493 2 0.034
protein metabolic process GO:0019538 183 0.034
opioid receptor signaling pathway GO:0038003 3 0.033
central nervous system segmentation GO:0035283 6 0.033
regulation of protein metabolic process GO:0051246 56 0.033
ventral spinal cord interneuron fate commitment GO:0060579 3 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.033
cellular protein catabolic process GO:0044257 4 0.033
programmed cell death GO:0012501 119 0.032
embryo development ending in birth or egg hatching GO:0009792 271 0.032
embryonic digestive tract morphogenesis GO:0048557 3 0.032
regulation of cell migration GO:0030334 40 0.032
Worm
renal system development GO:0072001 94 0.032
morphogenesis of an epithelial sheet GO:0002011 49 0.032
hematopoietic or lymphoid organ development GO:0048534 191 0.031
skeletal system development GO:0001501 181 0.030
muscle cell differentiation GO:0042692 139 0.030
neurological system process GO:0050877 62 0.030
retinal ganglion cell axon guidance GO:0031290 35 0.030
positive regulation of multicellular organismal process GO:0051240 52 0.029
Mouse
diencephalon morphogenesis GO:0048852 5 0.029
cellular component assembly GO:0022607 170 0.029
positive regulation of rna biosynthetic process GO:1902680 57 0.029
histone h3 k4 methylation GO:0051568 2 0.029
compound eye development GO:0048749 2 0.029
regulation of extent of cell growth GO:0061387 29 0.029
single organism metabolic process GO:0044710 217 0.028
synaptic target recognition GO:0008039 1 0.028
behavior GO:0007610 74 0.028
Worm
axonal fasciculation GO:0007413 11 0.028
regulation of transcription involved in cell fate commitment GO:0060850 1 0.028
fin morphogenesis GO:0033334 53 0.028
hypothalamus development GO:0021854 14 0.027
regulation of cell development GO:0060284 100 0.027
cardiac muscle cell differentiation GO:0055007 30 0.027
heart morphogenesis GO:0003007 156 0.027
regulation of endodermal cell fate specification GO:0042663 15 0.027
cellular response to organic substance GO:0071310 105 0.027
somitogenesis GO:0001756 87 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
regulation of neurogenesis GO:0050767 87 0.026
heart looping GO:0001947 94 0.026
cellular component biogenesis GO:0044085 178 0.026
embryonic skeletal system development GO:0048706 97 0.026
glomerulus development GO:0032835 27 0.026
regulation of cell differentiation GO:0045595 142 0.025
Zebrafish
negative regulation of rna metabolic process GO:0051253 48 0.025
Zebrafish Mouse
photoreceptor cell fate commitment GO:0046552 1 0.025
macromolecule modification GO:0043412 111 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
muscle cell development GO:0055001 115 0.025
dopaminergic neuron differentiation GO:0071542 14 0.025
regulation of developmental growth GO:0048638 38 0.025
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.025
Zebrafish
olfactory lobe development GO:0021988 4 0.024
Mouse
convergent extension involved in organogenesis GO:0060029 10 0.024
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.024
regulation of cellular ph GO:0030641 1 0.024
eye development GO:0001654 277 0.024
embryonic neurocranium morphogenesis GO:0048702 15 0.023
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.023
regulation of neuron migration GO:2001222 2 0.023
cognition GO:0050890 1 0.023
positive regulation of cellular process GO:0048522 201 0.023
catechol containing compound metabolic process GO:0009712 2 0.023
regulation of signaling GO:0023051 235 0.023
sensory perception of chemical stimulus GO:0007606 3 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
extraocular skeletal muscle development GO:0002074 3 0.022
facial nucleus development GO:0021754 7 0.022
facial nerve development GO:0021561 3 0.022
positive regulation of gliogenesis GO:0014015 2 0.022
response to drug GO:0042493 3 0.022
positive regulation of cell fate commitment GO:0010455 1 0.022
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.022
negative regulation of metabolic process GO:0009892 86 0.022
Zebrafish Mouse
motor neuron axon guidance GO:0008045 23 0.022
peripheral nervous system neuron differentiation GO:0048934 28 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
Zebrafish Mouse
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.022
negative regulation of neuron differentiation GO:0045665 10 0.021
cell growth GO:0016049 57 0.021
axon extension involved in axon guidance GO:0048846 10 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
Zebrafish Mouse
regeneration GO:0031099 91 0.021
liver development GO:0001889 96 0.021
apoptotic process GO:0006915 116 0.021
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.021
regulation of synaptic plasticity GO:0048167 1 0.021
habenula development GO:0021986 9 0.021
catechol containing compound biosynthetic process GO:0009713 2 0.021
bmp signaling pathway GO:0030509 52 0.020
neuroblast proliferation GO:0007405 2 0.020
response to alcohol GO:0097305 14 0.020
floor plate formation GO:0021508 12 0.020
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.020
negative regulation of neuron projection regeneration GO:0070571 4 0.020
dorsal ventral pattern formation GO:0009953 125 0.020
embryonic camera type eye formation GO:0060900 10 0.020
mesenchymal cell development GO:0014031 78 0.020
dorsal ventral axis specification GO:0009950 14 0.020
smooth muscle tissue development GO:0048745 1 0.020
post embryonic foregut morphogenesis GO:0048618 3 0.019
cardiac muscle tissue development GO:0048738 48 0.019
cellular amine metabolic process GO:0044106 2 0.019
response to alkaloid GO:0043279 2 0.019
regulation of neuron differentiation GO:0045664 56 0.019
regulation of axon extension involved in axon guidance GO:0048841 6 0.019
positive regulation of transport GO:0051050 2 0.019
regulation of cell death GO:0010941 103 0.019
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.019
catecholamine biosynthetic process GO:0042423 2 0.019
negative regulation of signaling GO:0023057 96 0.019
response to endogenous stimulus GO:0009719 83 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of embryonic development GO:0040019 3 0.018
system process GO:0003008 185 0.018
inner ear receptor cell development GO:0060119 20 0.018
glial cell differentiation GO:0010001 42 0.018
immune system development GO:0002520 191 0.018
cardiac cell fate commitment GO:0060911 1 0.018
dopamine metabolic process GO:0042417 2 0.018
regulation of system process GO:0044057 40 0.018
negative regulation of rna biosynthetic process GO:1902679 45 0.018
Zebrafish Mouse
cell migration involved in heart formation GO:0060974 10 0.018
hypothalamus cell differentiation GO:0021979 4 0.018
regulation of cell communication GO:0010646 232 0.018
monoamine transport GO:0015844 1 0.018
hormone secretion GO:0046879 2 0.018
neural crest cell differentiation GO:0014033 72 0.017
entrainment of circadian clock GO:0009649 2 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
Zebrafish Mouse
determination of left right symmetry GO:0007368 179 0.017
retinal cell programmed cell death GO:0046666 2 0.017
type b pancreatic cell development GO:0003323 4 0.017
endocardium morphogenesis GO:0003160 4 0.017
larval development GO:0002164 2 0.017
facial nerve morphogenesis GO:0021610 1 0.017
negative regulation of cellular process GO:0048523 283 0.017
Zebrafish Mouse
regulation of gliogenesis GO:0014013 6 0.017
auditory receptor cell differentiation GO:0042491 15 0.017
regulation of response to stimulus GO:0048583 269 0.017
organonitrogen compound biosynthetic process GO:1901566 47 0.017
hepatocyte proliferation GO:0072574 2 0.016
positive regulation of cell differentiation GO:0045597 30 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.016
medial fin development GO:0033338 16 0.016
organelle organization GO:0006996 227 0.016
somatic muscle development GO:0007525 4 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
Zebrafish Mouse
organelle assembly GO:0070925 110 0.016
circadian sleep wake cycle process GO:0022410 2 0.016
response to biotic stimulus GO:0009607 97 0.016
growth GO:0040007 174 0.016
Mouse
digestive tract development GO:0048565 265 0.016
Zebrafish
actin cytoskeleton organization GO:0030036 63 0.016
regulation of circadian rhythm GO:0042752 4 0.015
foregut morphogenesis GO:0007440 4 0.015
lateral inhibition GO:0046331 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
sexual reproduction GO:0019953 36 0.015
regulation of heart growth GO:0060420 2 0.015
response to external biotic stimulus GO:0043207 97 0.015
gabaergic neuron differentiation GO:0097154 2 0.015
Mouse
regulation of blood pressure GO:0008217 1 0.015
cell death GO:0008219 121 0.015
endocardium formation GO:0060214 1 0.015
positive regulation of cell development GO:0010720 25 0.015
neural plate development GO:0001840 10 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
pectoral fin development GO:0033339 50 0.015
leukocyte proliferation GO:0070661 1 0.015
commissural neuron axon guidance GO:0071679 3 0.015
nephron development GO:0072006 31 0.014
hematopoietic progenitor cell differentiation GO:0002244 23 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.014
peripheral nervous system neuron development GO:0048935 22 0.014
muscle tissue development GO:0060537 110 0.014
renal tubule morphogenesis GO:0061333 1 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
multicellular organismal response to stress GO:0033555 2 0.014
regulation of tube size GO:0035150 2 0.014
fin regeneration GO:0031101 51 0.014
regulation of heart contraction GO:0008016 32 0.014
axis specification GO:0009798 43 0.014
negative regulation of axon extension GO:0030517 7 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
myofibril assembly GO:0030239 48 0.013
chemosensory behavior GO:0007635 1 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
Worm
regulation of systemic arterial blood pressure GO:0003073 1 0.013
positive regulation of muscle tissue development GO:1901863 1 0.013
medial fin morphogenesis GO:0035141 14 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
cellular response to hypoxia GO:0071456 1 0.013
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 5 0.013
epithelial cell differentiation GO:0030855 116 0.013
optic placode formation involved in camera type eye formation GO:0046619 3 0.013
stem cell development GO:0048864 82 0.013
negative regulation of axon regeneration GO:0048681 4 0.013
neural plate morphogenesis GO:0001839 7 0.013
developmental cell growth GO:0048588 52 0.013
regulation of organ growth GO:0046620 3 0.013
Mouse
developmental programmed cell death GO:0010623 4 0.013
positive regulation of synapse assembly GO:0051965 1 0.013
urogenital system development GO:0001655 97 0.013
regulation of response to stress GO:0080134 36 0.013
nephron morphogenesis GO:0072028 2 0.012
midbrain development GO:0030901 28 0.012
cartilage morphogenesis GO:0060536 13 0.012
oxoacid metabolic process GO:0043436 31 0.012
amine metabolic process GO:0009308 2 0.012
eye morphogenesis GO:0048592 144 0.012
response to xenobiotic stimulus GO:0009410 45 0.012
spinal cord patterning GO:0021511 6 0.012
auditory receptor cell fate specification GO:0042667 2 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
macromolecule catabolic process GO:0009057 15 0.012
nerve development GO:0021675 45 0.012
lateral line development GO:0048882 66 0.012
cellular response to external stimulus GO:0071496 2 0.012
regulation of organ morphogenesis GO:2000027 35 0.012
Zebrafish
regulation of neurological system process GO:0031644 2 0.012
sensory perception GO:0007600 39 0.012
striated muscle cell proliferation GO:0014855 7 0.012
regulation of localization GO:0032879 104 0.012
Worm
cell migration involved in gastrulation GO:0042074 79 0.012
cardiac atrium development GO:0003230 4 0.012
water homeostasis GO:0030104 4 0.012
negative regulation of signal transduction GO:0009968 94 0.012
embryonic eye morphogenesis GO:0048048 30 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.011
cell cycle GO:0007049 93 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
digestive system development GO:0055123 289 0.011
Zebrafish
heart process GO:0003015 71 0.011
regulation of cell cycle process GO:0010564 20 0.011
regulation of apoptotic process GO:0042981 98 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
hindbrain development GO:0030902 91 0.011
skeletal system morphogenesis GO:0048705 102 0.011
biological adhesion GO:0022610 40 0.011

arx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.020
bone development disease DOID:0080006 0 0.020
bone disease DOID:0080001 0 0.020
disease of anatomical entity DOID:7 0 0.020
Human
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
acrocephalosyndactylia DOID:12960 0 0.013
dysostosis DOID:1934 0 0.013
synostosis DOID:11971 0 0.013
pfeiffer syndrome DOID:14705 0 0.012