Danio rerio

125 known processes

ascl1a

achaete-scute complex-like 1a (Drosophila)

(Aliases: Zash-1a,im:7138587,MGC109810,asha,zash1a,si:dkey-264k15.2,zasha,id:ibd5085,ash)

ascl1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oligodendrocyte differentiation GO:0048709 23 0.999
Mouse
central nervous system development GO:0007417 387 0.998
neuron projection morphogenesis GO:0048812 161 0.997
Worm
glial cell migration GO:0008347 3 0.996
diencephalon development GO:0021536 58 0.993
cellular component morphogenesis GO:0032989 336 0.992
Worm
generation of neurons GO:0048699 385 0.992
Human Mouse Worm
axon development GO:0061564 166 0.990
Worm
forebrain development GO:0030900 96 0.989
midbrain development GO:0030901 28 0.982
pancreatic a cell development GO:0003322 2 0.982
oligodendrocyte development GO:0014003 7 0.980
Mouse
neuron fate determination GO:0048664 2 0.976
cellular biosynthetic process GO:0044249 286 0.975
regulation of glial cell differentiation GO:0045685 4 0.975
axon extension GO:0048675 45 0.974
Worm
neuroblast fate determination GO:0007400 1 0.974
Mouse
forebrain neuron fate commitment GO:0021877 1 0.972
Mouse
skin development GO:0043588 54 0.971
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.971
Worm
forebrain neuron development GO:0021884 7 0.970
neuroblast proliferation GO:0007405 2 0.970
Mouse
regulation of multicellular organismal development GO:2000026 223 0.969
Human Mouse Worm
cell part morphogenesis GO:0032990 246 0.969
Worm
pituitary gland development GO:0021983 16 0.965
cellular aromatic compound metabolic process GO:0006725 295 0.964
neuron migration GO:0001764 22 0.963
Mouse Worm
axonogenesis GO:0007409 152 0.962
Worm
regulation of cell development GO:0060284 100 0.962
Human Mouse Worm
positive regulation of nervous system development GO:0051962 25 0.957
Mouse
regulation of oligodendrocyte differentiation GO:0048713 1 0.955
cell morphogenesis involved in differentiation GO:0000904 195 0.954
Worm
hair cell differentiation GO:0035315 32 0.952
ventral spinal cord interneuron differentiation GO:0021514 12 0.950
Mouse
gland development GO:0048732 143 0.947
positive regulation of neural precursor cell proliferation GO:2000179 1 0.945
Mouse
regulation of axonogenesis GO:0050770 32 0.944
Worm
auditory receptor cell fate commitment GO:0009912 4 0.942
regulation of neurogenesis GO:0050767 87 0.939
Human Mouse Worm
astrocyte differentiation GO:0048708 1 0.936
positive regulation of neurogenesis GO:0050769 24 0.935
Mouse
auditory receptor cell fate determination GO:0042668 2 0.930
inner ear receptor cell fate commitment GO:0060120 4 0.922
regulation of multicellular organismal process GO:0051239 277 0.919
Human Mouse Worm
aromatic compound biosynthetic process GO:0019438 217 0.919
nucleobase containing compound biosynthetic process GO:0034654 205 0.918
cell fate commitment GO:0045165 99 0.917
Human Mouse Worm
neuroblast differentiation GO:0014016 1 0.917
Mouse Worm
forebrain generation of neurons GO:0021872 14 0.913
Human Mouse
limbic system development GO:0021761 16 0.906
negative regulation of neurogenesis GO:0050768 20 0.902
Human
epidermal cell fate specification GO:0009957 4 0.901
regulation of response to stimulus GO:0048583 269 0.898
Mouse Worm Fly
adenohypophysis development GO:0021984 15 0.893
regulation of cell differentiation GO:0045595 142 0.893
Human Mouse Worm
rostrocaudal neural tube patterning GO:0021903 29 0.883
glial cell fate commitment GO:0021781 6 0.883
Mouse
axon guidance GO:0007411 86 0.879
Worm
telencephalon development GO:0021537 14 0.874
Mouse
nucleic acid metabolic process GO:0090304 244 0.873
organic cyclic compound metabolic process GO:1901360 301 0.873
positive regulation of cellular biosynthetic process GO:0031328 68 0.869
stem cell fate commitment GO:0048865 1 0.866
Mouse Worm
nucleobase containing compound metabolic process GO:0006139 274 0.866
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.865
regulation of mechanoreceptor differentiation GO:0045631 1 0.863
brain development GO:0007420 293 0.861
regulation of inner ear receptor cell differentiation GO:2000980 1 0.854
developmental process involved in reproduction GO:0003006 27 0.853
Fly
neuroblast fate commitment GO:0014017 1 0.852
Mouse Worm
positive regulation of cellular metabolic process GO:0031325 94 0.849
glial cell differentiation GO:0010001 42 0.847
Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.846
positive regulation of cell cycle GO:0045787 3 0.845
Mouse
neuron development GO:0048666 262 0.843
Mouse Worm
glial cell fate specification GO:0021780 4 0.842
Mouse
cell projection morphogenesis GO:0048858 244 0.842
Worm
regulation of neuron differentiation GO:0045664 56 0.840
Human Mouse Worm
regulation of rna metabolic process GO:0051252 224 0.839
epidermal cell differentiation GO:0009913 36 0.837
nucleic acid templated transcription GO:0097659 181 0.833
abducens nucleus development GO:0021742 2 0.832
ventral spinal cord interneuron fate commitment GO:0060579 3 0.827
Mouse
regulation of signaling GO:0023051 235 0.824
Mouse
stem cell differentiation GO:0048863 117 0.821
Mouse Worm
forebrain cell migration GO:0021885 1 0.817
cell differentiation in spinal cord GO:0021515 40 0.815
Mouse
oligodendrocyte cell fate specification GO:0021778 4 0.812
Mouse
epithelial cell differentiation GO:0030855 116 0.811
negative regulation of biological process GO:0048519 304 0.806
negative regulation of gliogenesis GO:0014014 1 0.799
inner ear receptor cell differentiation GO:0060113 29 0.790
positive regulation of biological process GO:0048518 253 0.790
cellular macromolecule biosynthetic process GO:0034645 224 0.790
neuron fate commitment GO:0048663 26 0.780
Human Mouse
endocrine system development GO:0035270 65 0.778
neuron projection guidance GO:0097485 86 0.769
Worm
positive regulation of metabolic process GO:0009893 108 0.763
camera type eye development GO:0043010 222 0.762
positive regulation of cell differentiation GO:0045597 30 0.757
Mouse
circulatory system process GO:0003013 87 0.753
positive regulation of biosynthetic process GO:0009891 68 0.747
cellular nitrogen compound biosynthetic process GO:0044271 218 0.742
hematopoietic stem cell differentiation GO:0060218 20 0.738
central nervous system myelination GO:0022010 2 0.738
heterocycle biosynthetic process GO:0018130 215 0.738
ameboidal type cell migration GO:0001667 143 0.736
stem cell fate determination GO:0048867 1 0.734
Mouse
neuron differentiation GO:0030182 353 0.728
Human Mouse Worm
spinal cord motor neuron differentiation GO:0021522 26 0.720
sympathetic nervous system development GO:0048485 3 0.714
neuron fate specification GO:0048665 20 0.713
Mouse
glucose homeostasis GO:0042593 1 0.706
neuron projection development GO:0031175 180 0.704
Worm
system process GO:0003008 185 0.703
negative regulation of nervous system development GO:0051961 22 0.702
Human
cell proliferation in forebrain GO:0021846 3 0.698
olfactory lobe development GO:0021988 4 0.696
positive regulation of developmental process GO:0051094 50 0.695
Mouse
cell fate specification GO:0001708 68 0.695
Mouse Worm
locomotion GO:0040011 313 0.693
Mouse Worm
regulation of cell morphogenesis GO:0022604 42 0.692
Worm
negative regulation of endothelial cell migration GO:0010596 1 0.687
dopaminergic neuron differentiation GO:0071542 14 0.685
positive regulation of epithelial cell differentiation GO:0030858 2 0.684
response to wounding GO:0009611 116 0.683
auditory receptor cell development GO:0060117 8 0.682
regulation of stem cell proliferation GO:0072091 2 0.679
inner ear receptor cell development GO:0060119 20 0.670
neural tube patterning GO:0021532 33 0.660
regulation of primary metabolic process GO:0080090 311 0.656
positive regulation of neuron migration GO:2001224 2 0.655
eye development GO:0001654 277 0.654
regulation of rna biosynthetic process GO:2001141 213 0.651
regulation of nucleic acid templated transcription GO:1903506 213 0.646
central nervous system neuron development GO:0021954 29 0.642
Mouse
nitrogen compound metabolic process GO:0006807 319 0.638
negative regulation of cell differentiation GO:0045596 46 0.633
Human
aorta morphogenesis GO:0035909 3 0.633
response to chemical GO:0042221 320 0.629
Human Worm
ventral spinal cord development GO:0021517 35 0.629
Mouse
tube morphogenesis GO:0035239 349 0.625
Fly
pharyngeal muscle development GO:0043282 4 0.617
metencephalon development GO:0022037 27 0.616
Mouse
positive regulation of glial cell differentiation GO:0045687 1 0.615
hypochord development GO:0055016 3 0.615
cell projection organization GO:0030030 284 0.612
Worm
organonitrogen compound metabolic process GO:1901564 74 0.611
Fly
mechanoreceptor differentiation GO:0042490 37 0.608
cellular component movement GO:0006928 335 0.608
Mouse Worm
rna metabolic process GO:0016070 219 0.604
epidermis development GO:0008544 48 0.604
pancreatic d cell differentiation GO:0003311 2 0.602
olfactory bulb development GO:0021772 4 0.600
regulation of neural precursor cell proliferation GO:2000177 3 0.597
Mouse
response to external stimulus GO:0009605 264 0.592
Mouse Worm Fly
digestive system development GO:0055123 289 0.590
Mouse Fly
peripheral nervous system development GO:0007422 55 0.590
Fly
regulation of nervous system development GO:0051960 90 0.589
Human Mouse Worm
positive regulation of rna biosynthetic process GO:1902680 57 0.587
regulation of cellular metabolic process GO:0031323 320 0.586
regulation of locomotion GO:0040012 55 0.583
Worm
gliogenesis GO:0042063 45 0.579
Mouse
regulation of cell projection organization GO:0031344 44 0.576
Worm
endocardium formation GO:0060214 1 0.574
regulation of biosynthetic process GO:0009889 250 0.572
stem cell maintenance GO:0019827 4 0.571
regulation of gene expression GO:0010468 265 0.569
cell morphogenesis GO:0000902 289 0.561
Worm
regulation of axon extension GO:0030516 24 0.561
Worm
positive regulation of nucleic acid templated transcription GO:1903508 57 0.561
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.561
Worm
cardiac chamber formation GO:0003207 4 0.558
positive regulation of neuron differentiation GO:0045666 12 0.555
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.551
stem cell development GO:0048864 82 0.551
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.550
Human Mouse Fly
cell motility GO:0048870 244 0.549
Mouse Worm
camera type eye morphogenesis GO:0048593 108 0.549
regulation of macromolecule biosynthetic process GO:0010556 225 0.547
axon ensheathment in central nervous system GO:0032291 2 0.546
patterning of lymph vessels GO:0060854 1 0.545
water homeostasis GO:0030104 4 0.544
positive regulation of rna metabolic process GO:0051254 59 0.541
auditory receptor cell differentiation GO:0042491 15 0.540
larval development GO:0002164 2 0.528
Worm
mesenchymal cell differentiation GO:0048762 87 0.527
cell proliferation GO:0008283 80 0.524
Mouse Fly
taxis GO:0042330 109 0.515
Worm
dendrite morphogenesis GO:0048813 5 0.512
forebrain dorsal ventral pattern formation GO:0021798 1 0.511
positive regulation of cell development GO:0010720 25 0.505
Mouse
aorta development GO:0035904 4 0.503
positive regulation of cellular process GO:0048522 201 0.502
dorsal ventral pattern formation GO:0009953 125 0.496
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.494
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.493
regulation of metabolic process GO:0019222 359 0.485
hematopoietic progenitor cell differentiation GO:0002244 23 0.485
hindbrain development GO:0030902 91 0.484
negative regulation of cell development GO:0010721 26 0.483
Human
developmental programmed cell death GO:0010623 4 0.481
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.476
midbrain hindbrain boundary development GO:0030917 23 0.475
transcription from rna polymerase ii promoter GO:0006366 80 0.475
Human Mouse Worm Fly
spinal cord dorsal ventral patterning GO:0021513 5 0.474
Mouse
transcription dna templated GO:0006351 181 0.471
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.469
carbohydrate homeostasis GO:0033500 1 0.463
anterior commissure morphogenesis GO:0021960 3 0.462
positive regulation of macromolecule metabolic process GO:0010604 93 0.461
somitogenesis GO:0001756 87 0.461
type b pancreatic cell development GO:0003323 4 0.455
organic cyclic compound biosynthetic process GO:1901362 223 0.453
regulation of cellular biosynthetic process GO:0031326 245 0.444
regulation of anatomical structure morphogenesis GO:0022603 130 0.442
Worm
negative regulation of developmental process GO:0051093 65 0.440
Human
negative regulation of epithelial cell migration GO:0010633 1 0.436
regulation of biological quality GO:0065008 263 0.436
Worm
regulation of neuron migration GO:2001222 2 0.435
regulation of hormone secretion GO:0046883 2 0.430
neural precursor cell proliferation GO:0061351 20 0.430
Mouse
endoderm development GO:0007492 49 0.428
negative regulation of cellular process GO:0048523 283 0.428
Human Fly
cell surface receptor signaling pathway GO:0007166 325 0.427
Human Mouse
multicellular organismal response to stress GO:0033555 2 0.424
regulation of cell communication GO:0010646 232 0.417
Mouse
macromolecule biosynthetic process GO:0009059 227 0.412
digestive tract morphogenesis GO:0048546 231 0.412
Fly
rna biosynthetic process GO:0032774 181 0.411
positive regulation of signaling GO:0023056 56 0.411
Mouse
retina layer formation GO:0010842 24 0.410
embryonic camera type eye development GO:0031076 29 0.392
negative regulation of multicellular organismal process GO:0051241 69 0.389
Human
response to radiation GO:0009314 51 0.386
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.384
regulation of cell death GO:0010941 103 0.379
Human Mouse Worm Fly
response to abiotic stimulus GO:0009628 122 0.378
blood vessel morphogenesis GO:0048514 216 0.377
cell cell signaling GO:0007267 52 0.377
regulation of cell cycle GO:0051726 52 0.373
Mouse Fly
spinal cord development GO:0021510 46 0.372
Mouse
lens morphogenesis in camera type eye GO:0002089 7 0.372
signal transduction GO:0007165 455 0.370
Human Mouse
motor neuron axon guidance GO:0008045 23 0.369
biosynthetic process GO:0009058 294 0.368
regulation of neuron projection development GO:0010975 40 0.363
Worm
apoptotic process GO:0006915 116 0.363
Human Mouse Fly
inner ear morphogenesis GO:0042472 63 0.361
autonomic nervous system development GO:0048483 19 0.361
positive regulation of notch signaling pathway GO:0045747 3 0.360
Mouse
glandular epithelial cell differentiation GO:0002067 9 0.360
Mouse
renal system development GO:0072001 94 0.360
Fly
photoreceptor cell fate commitment GO:0046552 1 0.359
thyroid gland development GO:0030878 12 0.356
regulation of endodermal cell fate specification GO:0042663 15 0.356
positive regulation of gliogenesis GO:0014015 2 0.355
regulation of nitrogen compound metabolic process GO:0051171 251 0.354
neural crest cell migration GO:0001755 42 0.354
enteroendocrine cell differentiation GO:0035883 9 0.352
neuron projection extension GO:1990138 45 0.352
Worm
forebrain regionalization GO:0021871 4 0.349
regulation of stem cell differentiation GO:2000736 4 0.348
cellular response to growth factor stimulus GO:0071363 39 0.341
forebrain anterior posterior pattern specification GO:0021797 3 0.341
negative regulation of macromolecule metabolic process GO:0010605 76 0.340
blood circulation GO:0008015 87 0.333
ensheathment of neurons GO:0007272 18 0.330
immune system process GO:0002376 241 0.327
Fly
exocrine system development GO:0035272 28 0.325
negative regulation of apoptotic process GO:0043066 55 0.323
Human Fly
hindbrain morphogenesis GO:0021575 22 0.317
stem cell proliferation GO:0072089 4 0.315
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.315
Human
response to growth factor GO:0070848 39 0.313
posterior lateral line development GO:0048916 38 0.312
forebrain midbrain boundary formation GO:0021905 1 0.310
regulation of synaptic plasticity GO:0048167 1 0.309
cell growth GO:0016049 57 0.309
Worm
mesenchymal cell development GO:0014031 78 0.309
heterocycle metabolic process GO:0046483 290 0.306
lateral inhibition GO:0046331 1 0.306
negative regulation of metabolic process GO:0009892 86 0.303
negative regulation of neuron differentiation GO:0045665 10 0.300
Human
cerebellar cortex development GO:0021695 5 0.298
regulation of apoptotic process GO:0042981 98 0.297
Human Mouse Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.297
Human
eye morphogenesis GO:0048592 144 0.294
cell cell signaling involved in cell fate commitment GO:0045168 12 0.290
gabaergic neuron differentiation GO:0097154 2 0.288
Human
glial cell development GO:0021782 20 0.287
Mouse
oxoacid metabolic process GO:0043436 31 0.286
chemotaxis GO:0006935 104 0.286
Worm
cell fate specification involved in pattern specification GO:0060573 3 0.285
organelle organization GO:0006996 227 0.278
Fly
cilium morphogenesis GO:0060271 85 0.277
locus ceruleus development GO:0021703 3 0.276
lens development in camera type eye GO:0002088 22 0.274
determination of bilateral symmetry GO:0009855 204 0.271
embryonic heart tube formation GO:0003144 1 0.271
inner ear development GO:0048839 126 0.270
ear development GO:0043583 127 0.266
posterior lateral line system development GO:0048915 46 0.266
keratinocyte differentiation GO:0030216 0 0.262
reproductive process GO:0022414 40 0.258
Worm Fly
polarized epithelial cell differentiation GO:0030859 4 0.258
regulation of axon guidance GO:1902667 8 0.258
Worm
negative regulation of cell death GO:0060548 60 0.258
Human Fly
regulation of molecular function GO:0065009 70 0.253
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.253
formation of primary germ layer GO:0001704 62 0.252
negative regulation of protein phosphorylation GO:0001933 4 0.247
positive regulation of cell fate specification GO:0042660 1 0.247
head development GO:0060322 303 0.246
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.246
positive regulation of transcription dna templated GO:0045893 57 0.245
somatic motor neuron differentiation GO:0021523 5 0.244
localization of cell GO:0051674 244 0.243
Mouse Worm
muscle cell differentiation GO:0042692 139 0.239
homeostatic process GO:0042592 142 0.232
regulation of gliogenesis GO:0014013 6 0.228
positive regulation of gene expression GO:0010628 71 0.228
cerebellum development GO:0021549 17 0.227
immune system development GO:0002520 191 0.226
retinal cell programmed cell death GO:0046666 2 0.226
neural crest cell development GO:0014032 62 0.225
extracellular matrix organization GO:0030198 27 0.224
negative regulation of programmed cell death GO:0043069 58 0.223
Human Fly
fin regeneration GO:0031101 51 0.223
regulation of transcription involved in cell fate commitment GO:0060850 1 0.222
response to light stimulus GO:0009416 46 0.222
lateral line development GO:0048882 66 0.221
neural crest cell differentiation GO:0014033 72 0.217
artery morphogenesis GO:0048844 14 0.216
regulation of dendrite morphogenesis GO:0048814 3 0.214
cellular response to prostaglandin stimulus GO:0071379 3 0.213
blood vessel development GO:0001568 246 0.210
photoreceptor cell differentiation GO:0046530 55 0.210
diencephalon morphogenesis GO:0048852 5 0.208
regulation of phosphorus metabolic process GO:0051174 43 0.207
cellular response to endogenous stimulus GO:0071495 68 0.207
pancreatic a cell differentiation GO:0003310 6 0.206
ectodermal placode development GO:0071696 37 0.206
regulation of embryonic development GO:0045995 47 0.205
central nervous system neuron differentiation GO:0021953 74 0.205
Human Mouse
forebrain neuron differentiation GO:0021879 14 0.204
Human Mouse
negative regulation of biosynthetic process GO:0009890 55 0.203
Human
regulation of cardiac chamber formation GO:1901210 2 0.200
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.200
ventral spinal cord interneuron specification GO:0021521 3 0.197
cellular amide metabolic process GO:0043603 4 0.197
Fly
negative regulation of gene expression GO:0010629 65 0.197
cellular response to chemical stimulus GO:0070887 157 0.196
amide transport GO:0042886 12 0.195
morphogenesis of an epithelium GO:0002009 333 0.195
Fly
peripheral nervous system neuron development GO:0048935 22 0.194
central nervous system neuron axonogenesis GO:0021955 18 0.194
hormone transport GO:0009914 2 0.194
somatic stem cell maintenance GO:0035019 1 0.192
sensory organ development GO:0007423 393 0.189
small molecule metabolic process GO:0044281 77 0.188
membrane organization GO:0061024 21 0.185
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.183
cellular amine metabolic process GO:0044106 2 0.183
cellular component assembly involved in morphogenesis GO:0010927 107 0.181
floor plate development GO:0033504 15 0.180
otolith development GO:0048840 32 0.179
response to organic substance GO:0010033 153 0.179
Human
neuronal stem cell maintenance GO:0097150 2 0.178
positive regulation of endothelial cell differentiation GO:0045603 2 0.178
cardiocyte differentiation GO:0035051 44 0.178
pons development GO:0021548 11 0.177
Mouse
cognition GO:0050890 1 0.174
regulation of jak stat cascade GO:0046425 3 0.174
cellular nitrogen compound metabolic process GO:0034641 290 0.174
pancreatic d cell development GO:0003324 1 0.174
photoreceptor cell fate specification GO:0043704 1 0.171
positive regulation of locomotion GO:0040017 14 0.171
carboxylic acid metabolic process GO:0019752 22 0.171
axon ensheathment GO:0008366 18 0.170
artery development GO:0060840 22 0.167
dendrite development GO:0016358 9 0.167
regulation of extent of cell growth GO:0061387 29 0.165
Worm
regulation of cellular component movement GO:0051270 55 0.165
Worm
developmental growth GO:0048589 166 0.164
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.164
enzyme linked receptor protein signaling pathway GO:0007167 106 0.163
central nervous system myelin formation GO:0032289 1 0.163
negative regulation of stem cell differentiation GO:2000737 2 0.162
nerve development GO:0021675 45 0.162
regulation of cell size GO:0008361 29 0.162
Worm
regulation of epithelial cell proliferation GO:0050678 3 0.161
hormone secretion GO:0046879 2 0.161
rhombomere development GO:0021546 19 0.160
neurological system process GO:0050877 62 0.160
amine metabolic process GO:0009308 2 0.160
death GO:0016265 121 0.158
Human Mouse Worm Fly
spinal cord patterning GO:0021511 6 0.158
Mouse
thalamus development GO:0021794 6 0.155
peptide transport GO:0015833 1 0.154
endodermal cell differentiation GO:0035987 19 0.154
pancreas development GO:0031016 84 0.153
regulation of cell motility GO:2000145 46 0.152
positive regulation of catalytic activity GO:0043085 25 0.151
cell migration GO:0016477 237 0.149
Mouse Worm
endocardium morphogenesis GO:0003160 4 0.149
multicellular organismal signaling GO:0035637 22 0.149
epithelial cell fate commitment GO:0072148 11 0.148
regulation of cell proliferation GO:0042127 37 0.146
Mouse
anterior posterior pattern specification GO:0009952 152 0.145
brain segmentation GO:0035284 6 0.144
sensory system development GO:0048880 76 0.144
proximal distal pattern formation GO:0009954 1 0.144
regulation of signal transduction GO:0009966 225 0.143
Mouse
oligodendrocyte cell fate commitment GO:0021779 5 0.142
Mouse
ventral midline development GO:0007418 13 0.142
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.141
spinal cord motor neuron cell fate specification GO:0021520 8 0.140
positive regulation of cell proliferation GO:0008284 15 0.140
Mouse
photoreceptor cell development GO:0042461 40 0.140
regulation of cellular amine metabolic process GO:0033238 0 0.140
embryonic camera type eye morphogenesis GO:0048596 19 0.139
hepaticobiliary system development GO:0061008 98 0.139
tissue migration GO:0090130 37 0.139
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.138
Human
connective tissue development GO:0061448 99 0.138
negative regulation of rna biosynthetic process GO:1902679 45 0.136
Human
glial cell fate determination GO:0007403 1 0.136
negative regulation of cell migration GO:0030336 17 0.135
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.135
specification of symmetry GO:0009799 204 0.134
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.133
transport GO:0006810 220 0.133
regulation of cell growth GO:0001558 29 0.132
Worm
retina development in camera type eye GO:0060041 146 0.132
establishment of localization in cell GO:0051649 77 0.130
cellular macromolecule metabolic process GO:0044260 391 0.129
apoptotic process involved in morphogenesis GO:0060561 2 0.129
regulation of cell migration GO:0030334 40 0.129
response to endogenous stimulus GO:0009719 83 0.128
determination of intestine left right asymmetry GO:0071908 2 0.128
ear morphogenesis GO:0042471 64 0.128
epithelial cell development GO:0002064 42 0.125
positive regulation of multicellular organismal process GO:0051240 52 0.125
Mouse
regulation of programmed cell death GO:0043067 101 0.125
Human Mouse Worm Fly
specification of organ identity GO:0010092 2 0.124
vestibular receptor cell development GO:0060118 3 0.124
enteric nervous system development GO:0048484 12 0.123
post embryonic morphogenesis GO:0009886 4 0.123
cardiac muscle cell differentiation GO:0055007 30 0.120
notochord cell differentiation GO:0060034 18 0.120
sensory organ morphogenesis GO:0090596 200 0.120
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.119
fin morphogenesis GO:0033334 53 0.119
response to alkaloid GO:0043279 2 0.119
peripheral nervous system neuron axonogenesis GO:0048936 13 0.119
positive regulation of response to stimulus GO:0048584 80 0.118
Mouse
establishment of localization GO:0051234 244 0.118
gastrulation GO:0007369 208 0.117
single organism membrane organization GO:0044802 20 0.117
neural tube development GO:0021915 62 0.117
central nervous system projection neuron axonogenesis GO:0021952 15 0.116
embryonic limb morphogenesis GO:0030326 2 0.115
endodermal cell fate specification GO:0001714 17 0.115
positive regulation of molecular function GO:0044093 33 0.114
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.114
Worm
somite development GO:0061053 96 0.113
regulation of catalytic activity GO:0050790 55 0.113
single organism reproductive process GO:0044702 40 0.113
insulin like growth factor receptor signaling pathway GO:0048009 4 0.112
mammillary body development GO:0021767 4 0.111
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.111
Mouse
radial glial cell differentiation GO:0060019 2 0.110
liver development GO:0001889 96 0.110
peripheral nervous system neuron differentiation GO:0048934 28 0.109
developmental maturation GO:0021700 34 0.109
positive regulation of transport GO:0051050 2 0.109
cardiac cell fate commitment GO:0060911 1 0.108
cartilage development GO:0051216 96 0.107
regulation of cellular ketone metabolic process GO:0010565 7 0.106
single organism localization GO:1902578 225 0.105
angiogenesis GO:0001525 158 0.104
embryonic pattern specification GO:0009880 44 0.104
head morphogenesis GO:0060323 8 0.103
somite specification GO:0001757 12 0.103
organic substance biosynthetic process GO:1901576 289 0.102
cellular response to organic substance GO:0071310 105 0.101
tissue remodeling GO:0048771 4 0.100
response to glucose GO:0009749 3 0.099
response to stress GO:0006950 263 0.099
regulation of localization GO:0032879 104 0.099
Worm
compound eye development GO:0048749 2 0.099
mitotic cell cycle GO:0000278 64 0.098
Mouse Fly
otic placode formation GO:0043049 23 0.098

ascl1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.396
bone development disease DOID:0080006 0 0.177
bone disease DOID:0080001 0 0.177
musculoskeletal system disease DOID:17 0 0.177
connective tissue disease DOID:65 0 0.177