Danio rerio

0 known processes

atf4b2

activating transcription factor 4b2

(Aliases: zgc:171702,sb:eu681,wu:fb08f07)

atf4b2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.490
regulation of mrna splicing via spliceosome GO:0048024 3 0.371
alternative mrna splicing via spliceosome GO:0000380 1 0.353
larval development GO:0002164 2 0.315
regulation of mrna processing GO:0050684 3 0.180
regulation of gene expression GO:0010468 265 0.173
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.156
modification dependent macromolecule catabolic process GO:0043632 3 0.143
regulation of metabolic process GO:0019222 359 0.121
Human Mouse
multi organism reproductive process GO:0044703 36 0.119
nitrogen compound metabolic process GO:0006807 319 0.110
Human Mouse
gene expression GO:0010467 252 0.097
Human Mouse
rna splicing via transesterification reactions GO:0000375 10 0.094
regulation of macromolecule metabolic process GO:0060255 317 0.093
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.085
Human Mouse
guanosine containing compound catabolic process GO:1901069 2 0.085
cytoplasm organization GO:0007028 4 0.082
response to chemical GO:0042221 320 0.081
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.075
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.074
Human Mouse
maintenance of location GO:0051235 4 0.073
heterocycle metabolic process GO:0046483 290 0.073
Human Mouse
apoptotic process GO:0006915 116 0.071
Mouse
mrna metabolic process GO:0016071 20 0.068
response to stress GO:0006950 263 0.064
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.064
Human Mouse
positive regulation of secretion by cell GO:1903532 1 0.061
cellular nitrogen compound metabolic process GO:0034641 290 0.061
Human Mouse
negative regulation of biological process GO:0048519 304 0.059
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.058
Human Mouse
gtp catabolic process GO:0006184 2 0.058
rna metabolic process GO:0016070 219 0.058
Human Mouse
cellular component biogenesis GO:0044085 178 0.056
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.056
multi organism process GO:0051704 134 0.055
gtp metabolic process GO:0046039 4 0.055
immune system process GO:0002376 241 0.054
guanosine containing compound metabolic process GO:1901068 4 0.053
ubiquitin dependent protein catabolic process GO:0006511 3 0.052
cellular macromolecule metabolic process GO:0044260 391 0.052
Human Mouse
organelle fusion GO:0048284 3 0.051
positive regulation of cellular catabolic process GO:0031331 3 0.048
development of primary female sexual characteristics GO:0046545 4 0.048
single organism reproductive process GO:0044702 40 0.046
regulation of macromolecule biosynthetic process GO:0010556 225 0.046
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.045
single organism membrane fusion GO:0044801 2 0.045
positive regulation of cellular process GO:0048522 201 0.045
Human Mouse
programmed cell death GO:0012501 119 0.044
Mouse
positive regulation of biological process GO:0048518 253 0.044
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.044
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.044
Human Mouse
regulation of reproductive process GO:2000241 4 0.043
establishment of localization GO:0051234 244 0.043
embryonic cranial skeleton morphogenesis GO:0048701 90 0.042
regulation of primary metabolic process GO:0080090 311 0.041
Human Mouse
lipid storage GO:0019915 1 0.041
central nervous system development GO:0007417 387 0.041
generation of neurons GO:0048699 385 0.040
regulation of rna metabolic process GO:0051252 224 0.040
Human Mouse
behavior GO:0007610 74 0.039
cellular response to chemical stimulus GO:0070887 157 0.039
Human
mitotic nuclear division GO:0007067 18 0.039
golgi vesicle transport GO:0048193 3 0.039
aging GO:0007568 2 0.037
cellular response to extracellular stimulus GO:0031668 2 0.037
oogenesis GO:0048477 14 0.036
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.036
Human Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.036
positive regulation of exocytosis GO:0045921 1 0.035
regulation of biosynthetic process GO:0009889 250 0.035
Human Mouse
heterocycle catabolic process GO:0046700 15 0.034
regulation of response to stimulus GO:0048583 269 0.034
Human
cellular response to external stimulus GO:0071496 2 0.034
oocyte anterior posterior axis specification GO:0007314 4 0.033
muscle tissue development GO:0060537 110 0.033
cellular response to nutrient levels GO:0031669 2 0.033
adult behavior GO:0030534 2 0.033
digestive tract morphogenesis GO:0048546 231 0.033
compound eye development GO:0048749 2 0.033
single organism localization GO:1902578 225 0.033
regulation of gtp catabolic process GO:0033124 2 0.032
positive regulation of secretion GO:0051047 1 0.032
regulation of autophagy GO:0010506 3 0.032
cell morphogenesis involved in differentiation GO:0000904 195 0.032
blood vessel development GO:0001568 246 0.032
acylglycerol homeostasis GO:0055090 2 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.032
cellular carbohydrate metabolic process GO:0044262 4 0.032
protein secretion GO:0009306 1 0.031
regulation of nucleoside metabolic process GO:0009118 2 0.031
regulation of exocytosis GO:0017157 1 0.031
exocytosis GO:0006887 1 0.031
cellular biosynthetic process GO:0044249 286 0.031
Human Mouse
regulation of cell death GO:0010941 103 0.031
Human Mouse
regulation of neurotransmitter secretion GO:0046928 1 0.031
positive regulation of nucleoside metabolic process GO:0045979 1 0.030
female sex differentiation GO:0046660 4 0.030
cell death GO:0008219 121 0.030
Human Mouse
neurotransmitter transport GO:0006836 2 0.030
neuron development GO:0048666 262 0.029
stem cell differentiation GO:0048863 117 0.029
stem cell maintenance GO:0019827 4 0.029
rna processing GO:0006396 25 0.029
female gonad development GO:0008585 4 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.028
Human Mouse
membrane fusion GO:0061025 2 0.028
translational initiation GO:0006413 3 0.028
modification dependent protein catabolic process GO:0019941 3 0.028
positive regulation of cell cycle GO:0045787 3 0.028
carbohydrate biosynthetic process GO:0016051 1 0.028
Mouse
cellular protein catabolic process GO:0044257 4 0.027
phagocytosis GO:0006909 3 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
axonogenesis GO:0007409 152 0.027
regulation of neurotransmitter transport GO:0051588 1 0.027
embryonic organ development GO:0048568 381 0.027
digestive tract development GO:0048565 265 0.027
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.027
Human
cell cycle process GO:0022402 53 0.027
muscle organ development GO:0007517 101 0.026
muscle structure development GO:0061061 196 0.026
chordate embryonic development GO:0043009 271 0.026
small molecule metabolic process GO:0044281 77 0.026
striated muscle tissue development GO:0014706 110 0.026
meiotic nuclear division GO:0007126 4 0.025
pole plasm assembly GO:0007315 4 0.025
regulation of cell differentiation GO:0045595 142 0.025
neuron differentiation GO:0030182 353 0.025
phagosome maturation GO:0090382 1 0.025
regulation of response to nutrient levels GO:0032107 1 0.025
rna modification GO:0009451 2 0.025
skeletal muscle tissue development GO:0007519 67 0.025
regulation of hormone secretion GO:0046883 2 0.025
endosome organization GO:0007032 2 0.025
nucleic acid templated transcription GO:0097659 181 0.024
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.024
Human Mouse
axon development GO:0061564 166 0.024
organic substance biosynthetic process GO:1901576 289 0.024
Human Mouse
response to uv GO:0009411 3 0.024
intracellular mrna localization GO:0008298 1 0.024
germ cell development GO:0007281 22 0.024
regulation of dna templated transcription in response to stress GO:0043620 0 0.024
Human Mouse
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.023
regulation of cell activation GO:0050865 1 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
multicellular organismal metabolic process GO:0044236 2 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
Human Mouse
positive regulation of gtpase activity GO:0043547 1 0.023
positive regulation of transport GO:0051050 2 0.023
regulation of transcription dna templated GO:0006355 213 0.023
Human Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
neurotransmitter secretion GO:0007269 2 0.022
locomotor rhythm GO:0045475 3 0.022
multicellular organism growth GO:0035264 4 0.022
hormone transport GO:0009914 2 0.021
cellular catabolic process GO:0044248 27 0.021
mitotic cell cycle process GO:1903047 48 0.021
signal transduction in absence of ligand GO:0038034 1 0.021
cell projection organization GO:0030030 284 0.021
cellular response to starvation GO:0009267 1 0.021
negative regulation of rna splicing GO:0033119 1 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
cell cycle g2 m phase transition GO:0044839 4 0.021
developmental maturation GO:0021700 34 0.021
signal transduction GO:0007165 455 0.021
Mouse
purine containing compound metabolic process GO:0072521 29 0.021
locomotion GO:0040011 313 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
regulation of cytokine production GO:0001817 3 0.020
death GO:0016265 121 0.020
Human Mouse
regulation of signal transduction GO:0009966 225 0.020
gastrulation GO:0007369 208 0.020
regulation of synapse organization GO:0050807 3 0.020
cellular component morphogenesis GO:0032989 336 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
negative regulation of metabolic process GO:0009892 86 0.020
amino acid transport GO:0006865 2 0.020
cell substrate adhesion GO:0031589 4 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
regulation of developmental process GO:0050793 247 0.020
brain development GO:0007420 293 0.020
meiotic chromosome segregation GO:0045132 3 0.020
meiotic cell cycle process GO:1903046 3 0.020
somatic muscle development GO:0007525 4 0.019
positive regulation of metabolic process GO:0009893 108 0.019
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
Human Mouse
establishment of protein localization to organelle GO:0072594 4 0.019
tissue remodeling GO:0048771 4 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
developmental growth GO:0048589 166 0.019
anterior posterior pattern specification GO:0009952 152 0.019
regulation of multicellular organism growth GO:0040014 4 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
negative regulation of cellular process GO:0048523 283 0.018
Human
negative regulation of gene expression GO:0010629 65 0.018
cytokinesis GO:0000910 3 0.018
regulation of gtpase activity GO:0043087 2 0.018
vacuolar transport GO:0007034 2 0.018
autophagy GO:0006914 4 0.018
mrna processing GO:0006397 14 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.018
cell cycle arrest GO:0007050 1 0.017
protein targeting to vacuole GO:0006623 1 0.017
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.017
ras protein signal transduction GO:0007265 7 0.017
vasculature development GO:0001944 278 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.017
peptide transport GO:0015833 1 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
biosynthetic process GO:0009058 294 0.017
Human Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
regulation of protein catabolic process GO:0042176 1 0.017
macromolecular complex subunit organization GO:0043933 74 0.016
cell cycle GO:0007049 93 0.016
transcription dna templated GO:0006351 181 0.016
Human Mouse
regulation of programmed cell death GO:0043067 101 0.016
Mouse
organic cyclic compound catabolic process GO:1901361 15 0.016
response to organic substance GO:0010033 153 0.016
regulation of cell communication GO:0010646 232 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.016
synaptic vesicle localization GO:0097479 1 0.016
heart development GO:0007507 313 0.016
antimicrobial humoral response GO:0019730 2 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
Human Mouse
g2 m transition of mitotic cell cycle GO:0000086 4 0.016
stem cell proliferation GO:0072089 4 0.016
double strand break repair GO:0006302 3 0.016
establishment of protein localization to vacuole GO:0072666 1 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
Human Mouse
amine metabolic process GO:0009308 2 0.016
endosomal transport GO:0016197 2 0.016
head development GO:0060322 303 0.016
recombinational repair GO:0000725 1 0.016
rna localization GO:0006403 4 0.016
mrna splicing via spliceosome GO:0000398 10 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
Human Mouse
transmission of nerve impulse GO:0019226 19 0.016
growth GO:0040007 174 0.016
female meiotic division GO:0007143 2 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
response to endogenous stimulus GO:0009719 83 0.016
neuron remodeling GO:0016322 1 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
Human Mouse
hormone secretion GO:0046879 2 0.015
cell migration GO:0016477 237 0.015
cellular component assembly GO:0022607 170 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
angiogenesis GO:0001525 158 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.015
cellular component movement GO:0006928 335 0.015
response to abiotic stimulus GO:0009628 122 0.015
protein dephosphorylation GO:0006470 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
mitotic metaphase plate congression GO:0007080 1 0.015
regulation of organ growth GO:0046620 3 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
reproductive process GO:0022414 40 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
cellular nitrogen compound catabolic process GO:0044270 15 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
regulation of epidermis development GO:0045682 2 0.015
pancreas development GO:0031016 84 0.015
neuron projection morphogenesis GO:0048812 161 0.015
response to glucose GO:0009749 3 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
Human Mouse
skeletal muscle organ development GO:0060538 78 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
nuclear transport GO:0051169 4 0.014
developmental cell growth GO:0048588 52 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
protein localization to vacuole GO:0072665 1 0.014
secondary metabolic process GO:0019748 3 0.014
nucleobase containing compound catabolic process GO:0034655 15 0.014
transport GO:0006810 220 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
response to drug GO:0042493 3 0.014
multicellular organism reproduction GO:0032504 35 0.013
viral process GO:0016032 1 0.013
positive regulation of catabolic process GO:0009896 4 0.013
negative regulation of catabolic process GO:0009895 3 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
microtubule organizing center organization GO:0031023 1 0.013
tube morphogenesis GO:0035239 349 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
cellular amine metabolic process GO:0044106 2 0.013
double strand break repair via homologous recombination GO:0000724 1 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
organelle assembly GO:0070925 110 0.013
collagen metabolic process GO:0032963 2 0.013
skeletal system development GO:0001501 181 0.013
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
Human Mouse
hindbrain development GO:0030902 91 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
response to hexose GO:0009746 3 0.013
negative regulation of cell death GO:0060548 60 0.013
Human
spindle assembly involved in mitosis GO:0090307 1 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
positive regulation of translation GO:0045727 1 0.013
macroautophagy GO:0016236 1 0.013
neural crest cell development GO:0014032 62 0.013
regulation of binding GO:0051098 3 0.013
cell proliferation GO:0008283 80 0.012
septum transversum development GO:0003343 4 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
mitotic cell cycle GO:0000278 64 0.012
phosphorus metabolic process GO:0006793 109 0.012
cellular response to hypoxia GO:0071456 1 0.012
immune system development GO:0002520 191 0.012
neuronal action potential GO:0019228 18 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
regulation of protein transport GO:0051223 3 0.012
response to alkaloid GO:0043279 2 0.012
regulation of cellular response to oxidative stress GO:1900407 2 0.012
Human
meiosis ii GO:0007135 1 0.012
mesenchymal cell development GO:0014031 78 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.012
regulation of carbohydrate biosynthetic process GO:0043255 1 0.012
cell projection morphogenesis GO:0048858 244 0.012
single organism transport GO:0044765 206 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
anatomical structure homeostasis GO:0060249 36 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
blood vessel morphogenesis GO:0048514 216 0.012
system process GO:0003008 185 0.012
neuron projection development GO:0031175 180 0.011
cellular response to organic substance GO:0071310 105 0.011
spermatid differentiation GO:0048515 2 0.011
regulation of dendrite development GO:0050773 3 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
Human Mouse
interspecies interaction between organisms GO:0044419 4 0.011
regulation of wound healing GO:0061041 2 0.011
lysosomal transport GO:0007041 2 0.011
positive regulation of neural precursor cell proliferation GO:2000179 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
endocrine hormone secretion GO:0060986 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
gamete generation GO:0007276 33 0.011
neuron death GO:0070997 21 0.011
Human Mouse
cellular response to decreased oxygen levels GO:0036294 1 0.011
rna splicing GO:0008380 16 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
astral microtubule organization GO:0030953 1 0.011
multicellular organismal macromolecule metabolic process GO:0044259 2 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
homeostatic process GO:0042592 142 0.011
multi organism cellular process GO:0044764 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
negative regulation of reproductive process GO:2000242 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
regulation of gene expression epigenetic GO:0040029 11 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
gastrulation with mouth forming second GO:0001702 44 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
regulation of establishment of protein localization GO:0070201 4 0.010
positive regulation of cell division GO:0051781 2 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.010
Human Mouse
centrosome organization GO:0051297 1 0.010
nuclear division GO:0000280 23 0.010
mesenchyme development GO:0060485 127 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
negative regulation of mitosis GO:0045839 3 0.010
regulation of rna splicing GO:0043484 8 0.010
negative regulation of multi organism process GO:0043901 3 0.010
wound healing GO:0042060 90 0.010
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.010
multicellular organismal signaling GO:0035637 22 0.010
regionalization GO:0003002 274 0.010
embryonic skeletal system development GO:0048706 97 0.010

atf4b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.030
disease of cellular proliferation DOID:14566 0 0.020
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.017
musculoskeletal system disease DOID:17 0 0.013