Danio rerio

56 known processes

atoh1a

atonal homolog 1a

(Aliases: zgc:136417,MGC136417,ath1,Atoh1.1,atoh1,ZATH-1,zath1)

atoh1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.998
ear development GO:0043583 127 0.990
eye development GO:0001654 277 0.982
Zebrafish Fly
forebrain development GO:0030900 96 0.981
Zebrafish Mouse
forebrain neuron development GO:0021884 7 0.981
Zebrafish
generation of neurons GO:0048699 385 0.980
polarized epithelial cell differentiation GO:0030859 4 0.972
Zebrafish
endocardium formation GO:0060214 1 0.967
Zebrafish
chordate embryonic development GO:0043009 271 0.965
Zebrafish
mechanosensory lateral line system development GO:0048881 49 0.964
skeletal system development GO:0001501 181 0.962
Zebrafish
embryonic organ development GO:0048568 381 0.953
Zebrafish Mouse
inner ear receptor cell development GO:0060119 20 0.951
neuron development GO:0048666 262 0.950
regionalization GO:0003002 274 0.950
Fly
auditory receptor cell fate determination GO:0042668 2 0.949
mechanoreceptor differentiation GO:0042490 37 0.945
central nervous system development GO:0007417 387 0.945
Zebrafish Mouse Fly
sensory organ morphogenesis GO:0090596 200 0.945
Zebrafish Mouse Fly
heart morphogenesis GO:0003007 156 0.940
Zebrafish
gene expression GO:0010467 252 0.937
Zebrafish Mouse Fly
posterior lateral line system development GO:0048915 46 0.935
olfactory lobe development GO:0021988 4 0.935
Zebrafish
neuron fate specification GO:0048665 20 0.934
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.927
Zebrafish
auditory receptor cell fate commitment GO:0009912 4 0.921
regulation of rna metabolic process GO:0051252 224 0.920
Zebrafish Mouse Fly
regulation of gene expression GO:0010468 265 0.910
Zebrafish Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.909
Mouse Fly
determination of intestine left right asymmetry GO:0071908 2 0.909
Zebrafish
inner ear development GO:0048839 126 0.907
posterior lateral line nerve development GO:0048918 8 0.899
Zebrafish
fin morphogenesis GO:0033334 53 0.883
Zebrafish
brain development GO:0007420 293 0.870
Zebrafish Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.864
Zebrafish Mouse Fly
lateral line nerve development GO:0048892 9 0.861
Zebrafish
regulation of mechanoreceptor differentiation GO:0045631 1 0.859
Mouse
cranial nerve development GO:0021545 42 0.858
Zebrafish
neuromast development GO:0048884 46 0.856
organic cyclic compound biosynthetic process GO:1901362 223 0.855
Zebrafish Mouse Fly
sensory system development GO:0048880 76 0.851
cell part morphogenesis GO:0032990 246 0.846
Mouse Fly
neuron differentiation GO:0030182 353 0.845
posterior lateral line development GO:0048916 38 0.842
formation of primary germ layer GO:0001704 62 0.842
Zebrafish
rhombomere development GO:0021546 19 0.841
rna biosynthetic process GO:0032774 181 0.834
Zebrafish Mouse Fly
regulation of inner ear receptor cell differentiation GO:2000980 1 0.833
Mouse
lateral line system development GO:0048925 76 0.830
regulation of cellular metabolic process GO:0031323 320 0.828
Zebrafish Mouse Fly
olfactory bulb development GO:0021772 4 0.822
Zebrafish
ear morphogenesis GO:0042471 64 0.813
Mouse
inner ear receptor cell differentiation GO:0060113 29 0.812
cellular aromatic compound metabolic process GO:0006725 295 0.807
Zebrafish Mouse Fly
camera type eye morphogenesis GO:0048593 108 0.806
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.803
Zebrafish Mouse Fly
lateral line development GO:0048882 66 0.801
neuron projection morphogenesis GO:0048812 161 0.801
Mouse Fly
nerve development GO:0021675 45 0.791
Zebrafish
axon regeneration GO:0031103 14 0.788
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.782
Zebrafish Mouse Fly
septum transversum development GO:0003343 4 0.780
Zebrafish
swimming behavior GO:0036269 8 0.777
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.775
Zebrafish Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.769
Zebrafish Mouse Fly
mesoderm formation GO:0001707 43 0.758
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.752
Zebrafish Mouse Fly
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.746
appendage development GO:0048736 80 0.733
Zebrafish Fly
regulation of multicellular organismal process GO:0051239 277 0.732
Zebrafish Mouse
neuromast hair cell development GO:0035675 6 0.730
cell projection organization GO:0030030 284 0.728
Zebrafish Mouse Fly
hindbrain development GO:0030902 91 0.727
Zebrafish
regulation of cell differentiation GO:0045595 142 0.724
Zebrafish Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.718
Mouse Fly
endocardium morphogenesis GO:0003160 4 0.718
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.716
Zebrafish Mouse Fly
artery development GO:0060840 22 0.714
Zebrafish
hair cell differentiation GO:0035315 32 0.709
cardioblast differentiation GO:0010002 9 0.699
Zebrafish
embryonic hemopoiesis GO:0035162 53 0.697
Zebrafish
neuron fate determination GO:0048664 2 0.691
embryonic organ morphogenesis GO:0048562 274 0.678
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.678
Zebrafish Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.677
Zebrafish Mouse Fly
appendage morphogenesis GO:0035107 56 0.674
Zebrafish Fly
proepicardium development GO:0003342 4 0.666
Zebrafish
anterior lateral line nerve development GO:0048909 4 0.659
Zebrafish
thyroid gland development GO:0030878 12 0.656
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.640
Zebrafish Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.629
Zebrafish Mouse Fly
retina development in camera type eye GO:0060041 146 0.624
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.620
Zebrafish Mouse Fly
nucleic acid templated transcription GO:0097659 181 0.618
Zebrafish Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.617
Zebrafish Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.607
Zebrafish Mouse Fly
cell fate specification GO:0001708 68 0.606
Mouse
otolith development GO:0048840 32 0.602
Zebrafish
neuron fate commitment GO:0048663 26 0.602
regulation of metabolic process GO:0019222 359 0.597
Zebrafish Mouse Fly
glial cell migration GO:0008347 3 0.596
nucleic acid metabolic process GO:0090304 244 0.594
Zebrafish Mouse Fly
embryonic heart tube formation GO:0003144 1 0.587
Zebrafish
regeneration GO:0031099 91 0.573
Zebrafish
stem cell proliferation GO:0072089 4 0.562
embryonic heart tube development GO:0035050 133 0.561
Zebrafish
cell morphogenesis GO:0000902 289 0.561
Mouse Fly
programmed cell death GO:0012501 119 0.561
Mouse
endocrine system development GO:0035270 65 0.558
Zebrafish
positive regulation of epithelial cell differentiation GO:0030858 2 0.553
Zebrafish Mouse
axonogenesis GO:0007409 152 0.538
Mouse
neuron projection development GO:0031175 180 0.519
Zebrafish Mouse Fly
morphogenesis of embryonic epithelium GO:0016331 30 0.519
Zebrafish
camera type eye development GO:0043010 222 0.518
Zebrafish
transcription dna templated GO:0006351 181 0.517
Zebrafish Mouse Fly
regulation of neurogenesis GO:0050767 87 0.517
Zebrafish Mouse
neural plate development GO:0001840 10 0.511
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.508
Zebrafish Mouse Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.500
sensory perception GO:0007600 39 0.497
Fly
nitrogen compound metabolic process GO:0006807 319 0.490
Zebrafish Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.490
Zebrafish Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.488
Zebrafish Mouse Fly
positive regulation of endothelial cell differentiation GO:0045603 2 0.484
Zebrafish
regulation of nervous system development GO:0051960 90 0.483
Zebrafish Mouse
olfactory placode development GO:0071698 12 0.482
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.476
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.474
Zebrafish Mouse Fly
response to axon injury GO:0048678 14 0.469
Zebrafish
peripheral nervous system neuron differentiation GO:0048934 28 0.467
metencephalon development GO:0022037 27 0.467
cell fate commitment GO:0045165 99 0.466
response to wounding GO:0009611 116 0.460
Zebrafish
biosynthetic process GO:0009058 294 0.458
Zebrafish Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.449
Zebrafish Mouse Fly
reflex GO:0060004 2 0.443
hindbrain morphogenesis GO:0021575 22 0.440
Zebrafish
embryonic pectoral fin morphogenesis GO:0035118 24 0.438
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.435
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.426
Zebrafish
neuromast hair cell differentiation GO:0048886 12 0.425
cellular component movement GO:0006928 335 0.421
Mouse
embryonic skeletal system development GO:0048706 97 0.416
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.416
Zebrafish Mouse Fly
specification of organ identity GO:0010092 2 0.414
head development GO:0060322 303 0.412
Zebrafish Mouse Fly
inner ear morphogenesis GO:0042472 63 0.412
Mouse
neuron projection regeneration GO:0031102 16 0.407
Zebrafish
vestibular reflex GO:0060005 2 0.402
pharyngeal system development GO:0060037 18 0.392
Zebrafish
regulation of endodermal cell fate specification GO:0042663 15 0.386
positive regulation of metabolic process GO:0009893 108 0.386
Zebrafish Mouse Fly
neural retina development GO:0003407 49 0.384
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.384
Zebrafish Mouse Fly
cerebellum formation GO:0021588 2 0.382
cellular macromolecule metabolic process GO:0044260 391 0.381
Zebrafish Mouse Fly
heterocycle metabolic process GO:0046483 290 0.378
Zebrafish Mouse Fly
artery morphogenesis GO:0048844 14 0.375
Zebrafish
rna metabolic process GO:0016070 219 0.366
Zebrafish Mouse Fly
ectodermal placode development GO:0071696 37 0.366
Zebrafish
cardiocyte differentiation GO:0035051 44 0.365
Zebrafish
negative regulation of neurogenesis GO:0050768 20 0.358
Zebrafish
inner ear receptor cell fate commitment GO:0060120 4 0.356
adult behavior GO:0030534 2 0.355
pancreas development GO:0031016 84 0.346
Zebrafish
mesoderm development GO:0007498 88 0.340
Zebrafish
rhombomere formation GO:0021594 12 0.335
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.335
Zebrafish Mouse Fly
positive regulation of biological process GO:0048518 253 0.334
Zebrafish Mouse Fly
eye morphogenesis GO:0048592 144 0.334
Zebrafish Fly
taxis GO:0042330 109 0.332
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.328
Fly
cell migration GO:0016477 237 0.323
Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.313
positive regulation of neurogenesis GO:0050769 24 0.296
Zebrafish Mouse
nephron morphogenesis GO:0072028 2 0.294
embryo development ending in birth or egg hatching GO:0009792 271 0.293
Zebrafish Worm
regulation of cell fate specification GO:0042659 20 0.293
aromatic compound biosynthetic process GO:0019438 217 0.290
Zebrafish Mouse Fly
neurological system process GO:0050877 62 0.290
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.289
Zebrafish Mouse Fly
somitogenesis GO:0001756 87 0.289
skeletal system morphogenesis GO:0048705 102 0.288
Zebrafish
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.286
retina layer formation GO:0010842 24 0.285
Zebrafish
neuromuscular process controlling balance GO:0050885 3 0.284
positive regulation of rna biosynthetic process GO:1902680 57 0.281
Zebrafish Mouse Fly
axon guidance GO:0007411 86 0.281
Mouse
erythrocyte differentiation GO:0030218 54 0.281
Zebrafish
hindbrain formation GO:0021576 3 0.281
cell motility GO:0048870 244 0.281
Mouse
pectoral fin development GO:0033339 50 0.274
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.273
Mouse
sensory perception of sound GO:0007605 9 0.272
Fly
regulation of developmental process GO:0050793 247 0.264
Zebrafish Mouse
muscle tissue development GO:0060537 110 0.263
cardiogenic plate morphogenesis GO:0003142 1 0.262
Zebrafish
posterior lateral line neuromast development GO:0048919 20 0.260
vestibular receptor cell development GO:0060118 3 0.259
primitive hemopoiesis GO:0060215 27 0.255
Zebrafish
positive regulation of cellular process GO:0048522 201 0.255
Zebrafish Mouse Fly
nephron epithelium morphogenesis GO:0072088 1 0.251
cell cycle GO:0007049 93 0.247
Zebrafish
negative regulation of gene expression GO:0010629 65 0.244
response to external stimulus GO:0009605 264 0.244
Mouse
signal transduction GO:0007165 455 0.241
Fly
positive regulation of transcription dna templated GO:0045893 57 0.240
Zebrafish Mouse Fly
locomotory behavior GO:0007626 34 0.239
Zebrafish
cellular component morphogenesis GO:0032989 336 0.238
Mouse Fly
tissue regeneration GO:0042246 74 0.235
angiogenesis GO:0001525 158 0.233
Zebrafish
skin development GO:0043588 54 0.230
muscle organ development GO:0007517 101 0.228
positive regulation of rna metabolic process GO:0051254 59 0.223
Zebrafish Mouse Fly
somite development GO:0061053 96 0.220
fin development GO:0033333 77 0.219
Zebrafish
tube morphogenesis GO:0035239 349 0.214
Zebrafish
fin regeneration GO:0031101 51 0.213
epithelial cell morphogenesis GO:0003382 2 0.212
epithelial tube formation GO:0072175 19 0.204
Zebrafish
neuroblast proliferation GO:0007405 2 0.199
transcription from rna polymerase ii promoter GO:0006366 80 0.192
Mouse Fly
locomotion GO:0040011 313 0.191
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.190
embryonic cranial skeleton morphogenesis GO:0048701 90 0.189
Zebrafish
segmentation GO:0035282 97 0.188
definitive hemopoiesis GO:0060216 18 0.188
Zebrafish
localization of cell GO:0051674 244 0.187
Mouse
determination of left right symmetry GO:0007368 179 0.184
Zebrafish
forebrain generation of neurons GO:0021872 14 0.183
Zebrafish
peripheral nervous system development GO:0007422 55 0.177
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.177
Zebrafish Mouse Fly
auditory receptor cell differentiation GO:0042491 15 0.174
immune system development GO:0002520 191 0.172
Zebrafish
regulation of neural retina development GO:0061074 2 0.172
erythrocyte homeostasis GO:0034101 55 0.168
Zebrafish
hemangioblast cell differentiation GO:0060217 5 0.166
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.164
Zebrafish
rhombomere morphogenesis GO:0021593 17 0.161
striated muscle tissue development GO:0014706 110 0.161
rhombomere boundary formation GO:0021654 10 0.161
negative regulation of developmental process GO:0051093 65 0.158
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.156
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.155
Zebrafish Mouse Fly
negative regulation of apoptotic process GO:0043066 55 0.154
Mouse
myeloid cell differentiation GO:0030099 86 0.154
Zebrafish
heart development GO:0007507 313 0.154
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.152
pons development GO:0021548 11 0.152
regulation of programmed cell death GO:0043067 101 0.150
Mouse
axonal fasciculation GO:0007413 11 0.150
Zebrafish
dopaminergic neuron differentiation GO:0071542 14 0.149
locus ceruleus development GO:0021703 3 0.148
regulation of primary metabolic process GO:0080090 311 0.147
Zebrafish Mouse Fly
regulation of cell development GO:0060284 100 0.146
Zebrafish Mouse
apoptotic process GO:0006915 116 0.145
Mouse
negative regulation of cell differentiation GO:0045596 46 0.144
Zebrafish
negative regulation of neuron projection regeneration GO:0070571 4 0.144
glial cell differentiation GO:0010001 42 0.142
ion transport GO:0006811 114 0.141
embryonic skeletal joint development GO:0072498 3 0.140
endothelium development GO:0003158 25 0.139
Zebrafish
hematopoietic stem cell differentiation GO:0060218 20 0.138
Zebrafish
sensory perception of mechanical stimulus GO:0050954 16 0.137
Fly
positive regulation of cell differentiation GO:0045597 30 0.135
Zebrafish Mouse
anterior posterior pattern specification GO:0009952 152 0.131
hematopoietic or lymphoid organ development GO:0048534 191 0.131
Zebrafish
tissue remodeling GO:0048771 4 0.131
exocrine system development GO:0035272 28 0.130
Zebrafish
otic vesicle development GO:0071599 42 0.129
aging GO:0007568 2 0.128
adenohypophysis development GO:0021984 15 0.127
negative regulation of cellular process GO:0048523 283 0.127
Zebrafish Mouse
gland development GO:0048732 143 0.127
Zebrafish
negative regulation of biosynthetic process GO:0009890 55 0.124
embryonic eye morphogenesis GO:0048048 30 0.124
positive regulation of stem cell proliferation GO:2000648 1 0.122
cell projection morphogenesis GO:0048858 244 0.121
Mouse Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.120
cell fate commitment involved in pattern specification GO:0060581 6 0.119
Fly
rhombomere 5 development GO:0021571 4 0.119
epithelial cell fate commitment GO:0072148 11 0.119
regulation of axonogenesis GO:0050770 32 0.118
negative regulation of nervous system development GO:0051961 22 0.117
Zebrafish
negative regulation of axon regeneration GO:0048681 4 0.117
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.116
Mouse Fly
positive regulation of gene expression GO:0010628 71 0.115
Zebrafish Mouse Fly
epithelial cell differentiation GO:0030855 116 0.115
specification of symmetry GO:0009799 204 0.113
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.112
Zebrafish
embryonic pattern specification GO:0009880 44 0.111
homeostasis of number of cells GO:0048872 62 0.111
Zebrafish
regulation of biological quality GO:0065008 263 0.111
Zebrafish
cellular amine metabolic process GO:0044106 2 0.109
behavior GO:0007610 74 0.107
Zebrafish Fly
establishment of localization GO:0051234 244 0.107
neuroblast differentiation GO:0014016 1 0.105
regulation of cellular amine metabolic process GO:0033238 0 0.105
epidermis development GO:0008544 48 0.105
stem cell maintenance GO:0019827 4 0.104
central nervous system neuron differentiation GO:0021953 74 0.103
Zebrafish
axon development GO:0061564 166 0.102
Zebrafish Mouse
axon extension GO:0048675 45 0.102
positive regulation of developmental process GO:0051094 50 0.102
Zebrafish Mouse
response to endogenous stimulus GO:0009719 83 0.101
cerebellum development GO:0021549 17 0.099
embryonic appendage morphogenesis GO:0035113 30 0.098
Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.098
cellular amino acid metabolic process GO:0006520 7 0.097
cellular response to stress GO:0033554 62 0.097
Zebrafish
single organism localization GO:1902578 225 0.096
telencephalon development GO:0021537 14 0.096
Zebrafish Mouse
myeloid cell homeostasis GO:0002262 56 0.095
Zebrafish
homeostatic process GO:0042592 142 0.095
Zebrafish
neuron projection guidance GO:0097485 86 0.094
Mouse
apoptotic process involved in morphogenesis GO:0060561 2 0.094
ectodermal placode morphogenesis GO:0071697 32 0.094
meiotic nuclear division GO:0007126 4 0.092
mesodermal cell migration GO:0008078 12 0.092
negative regulation of metabolic process GO:0009892 86 0.092
cell surface receptor signaling pathway GO:0007166 325 0.092
Fly
nephron tubule morphogenesis GO:0072078 1 0.091
gliogenesis GO:0042063 45 0.090
neuron recognition GO:0008038 18 0.089
Zebrafish Fly
neural nucleus development GO:0048857 15 0.089
organ formation GO:0048645 17 0.088
Fly
regulation of apoptotic process GO:0042981 98 0.088
Mouse
exocrine pancreas development GO:0031017 28 0.088
Zebrafish
cellular biosynthetic process GO:0044249 286 0.087
Zebrafish Mouse Fly
myeloid cell development GO:0061515 32 0.087
Zebrafish
hemopoiesis GO:0030097 183 0.087
Zebrafish
regulation of retina development in camera type eye GO:1902866 2 0.086
negative regulation of rna metabolic process GO:0051253 48 0.085
medial fin development GO:0033338 16 0.085
rostrocaudal neural tube patterning GO:0021903 29 0.084
neural precursor cell proliferation GO:0061351 20 0.084
embryonic viscerocranium morphogenesis GO:0048703 52 0.083
Zebrafish
mesodermal cell fate commitment GO:0001710 14 0.083
negative regulation of programmed cell death GO:0043069 58 0.081
Mouse
tube formation GO:0035148 25 0.081
Zebrafish
blood vessel development GO:0001568 246 0.080
Zebrafish
primary neural tube formation GO:0014020 1 0.080
tongue morphogenesis GO:0043587 3 0.080
post embryonic organ morphogenesis GO:0048563 1 0.078
Fly
regulation of cell fate commitment GO:0010453 22 0.078
regulation of axon extension GO:0030516 24 0.078
regulation of gastrulation GO:0010470 24 0.077
regulation of multicellular organismal development GO:2000026 223 0.076
Zebrafish Mouse
positive regulation of striated muscle tissue development GO:0045844 1 0.075
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.074
positive regulation of cellular metabolic process GO:0031325 94 0.074
Zebrafish Mouse Fly
neuron projection extension GO:1990138 45 0.073
cellular component biogenesis GO:0044085 178 0.073
mesenchymal cell proliferation GO:0010463 1 0.072
response to stress GO:0006950 263 0.072
Zebrafish
apoptotic signaling pathway GO:0097190 23 0.071
regulation of cell cycle GO:0051726 52 0.071
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.071
Mouse Fly
endothelial cell differentiation GO:0045446 20 0.070
Zebrafish
negative regulation of cell death GO:0060548 60 0.069
Mouse
mesenchyme development GO:0060485 127 0.067
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.067
regulation of cell death GO:0010941 103 0.067
Mouse
vestibular receptor cell differentiation GO:0060114 3 0.066
neuron death GO:0070997 21 0.066
microtubule based process GO:0007017 60 0.066
cellular component assembly GO:0022607 170 0.066
neuron apoptotic process GO:0051402 20 0.065
mesoderm morphogenesis GO:0048332 51 0.065
Zebrafish
nitrogen compound transport GO:0071705 23 0.065
organelle organization GO:0006996 227 0.064
regulation of embryonic development GO:0045995 47 0.062
renal tubule morphogenesis GO:0061333 1 0.062
protein complex subunit organization GO:0071822 46 0.061
cell division GO:0051301 20 0.060
negative regulation of biological process GO:0048519 304 0.060
Zebrafish Mouse
formation of anatomical boundary GO:0048859 14 0.060
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.060
stem cell differentiation GO:0048863 117 0.059
Zebrafish
embryonic camera type eye morphogenesis GO:0048596 19 0.059
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.058
neural plate morphogenesis GO:0001839 7 0.058
Zebrafish
organic acid metabolic process GO:0006082 31 0.057
regulation of epidermis development GO:0045682 2 0.056
Mouse
response to organic substance GO:0010033 153 0.055
endocardial cushion formation GO:0003272 2 0.055
cell recognition GO:0008037 19 0.055
Zebrafish Fly
mitotic cell cycle GO:0000278 64 0.054
pectoral fin morphogenesis GO:0035138 29 0.054
Zebrafish
cilium morphogenesis GO:0060271 85 0.053
cellular response to chemical stimulus GO:0070887 157 0.053
cell death GO:0008219 121 0.052
Mouse
response to external biotic stimulus GO:0043207 97 0.051
reproduction GO:0000003 40 0.051
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.051
Zebrafish Mouse Fly
endocardial cushion morphogenesis GO:0003203 3 0.051
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.050
central nervous system neuron development GO:0021954 29 0.050
Zebrafish
regulation of reproductive process GO:2000241 4 0.050
multi organism process GO:0051704 134 0.049
Fly
cell proliferation in forebrain GO:0021846 3 0.049
oligodendrocyte differentiation GO:0048709 23 0.049
vasculature development GO:0001944 278 0.049
Zebrafish
forebrain cell migration GO:0021885 1 0.048
endocardium development GO:0003157 9 0.048
Zebrafish
negative regulation of striated muscle tissue development GO:0045843 2 0.048
cytoskeleton organization GO:0007010 96 0.048
positive regulation of embryonic development GO:0040019 3 0.047
positive regulation of cell development GO:0010720 25 0.047
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.047
developmental growth GO:0048589 166 0.047
regulation of mesenchymal cell proliferation GO:0010464 1 0.047
small molecule metabolic process GO:0044281 77 0.046
determination of bilateral symmetry GO:0009855 204 0.046
Zebrafish
aorta morphogenesis GO:0035909 3 0.046
midbrain development GO:0030901 28 0.046
carboxylic acid metabolic process GO:0019752 22 0.045
death GO:0016265 121 0.045
Mouse
diencephalon development GO:0021536 58 0.045
anterior lateral line system development GO:0048898 9 0.043
Zebrafish
multicellular organismal signaling GO:0035637 22 0.043
epidermal cell differentiation GO:0009913 36 0.043
negative regulation of cellular metabolic process GO:0031324 77 0.043
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.043
microtubule cytoskeleton organization GO:0000226 33 0.042
forebrain neuron differentiation GO:0021879 14 0.042
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.042
regulation of organ morphogenesis GO:2000027 35 0.042
erythrocyte development GO:0048821 24 0.041
Zebrafish
aorta development GO:0035904 4 0.041
tongue development GO:0043586 3 0.041
cellular ketone metabolic process GO:0042180 11 0.041
larval development GO:0002164 2 0.041
cell migration in hindbrain GO:0021535 7 0.040
pharyngeal muscle development GO:0043282 4 0.040
regulation of mesodermal cell fate specification GO:0042661 9 0.040
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.040
preganglionic parasympathetic nervous system development GO:0021783 6 0.040
neural tube development GO:0021915 62 0.039
activation of mapk activity GO:0000187 3 0.039
developmental programmed cell death GO:0010623 4 0.039
pigmentation GO:0043473 85 0.038
cellular localization GO:0051641 97 0.038
embryonic skeletal joint morphogenesis GO:0060272 3 0.038
phosphate containing compound metabolic process GO:0006796 108 0.038
equilibrioception GO:0050957 2 0.037
embryonic camera type eye development GO:0031076 29 0.037
negative regulation of cell fate specification GO:0009996 11 0.036
response to light stimulus GO:0009416 46 0.036
notochord development GO:0030903 54 0.035
cell differentiation in spinal cord GO:0021515 40 0.035
regulation of endodermal cell differentiation GO:1903224 15 0.035
brain segmentation GO:0035284 6 0.035
dicarboxylic acid transport GO:0006835 1 0.035
rhombomere 6 development GO:0021572 4 0.034
dendrite development GO:0016358 9 0.034
Fly
transport GO:0006810 220 0.034
stem cell division GO:0017145 1 0.034
positive regulation of nervous system development GO:0051962 25 0.033
Zebrafish Mouse
regulation of neuron projection regeneration GO:0070570 7 0.033
compound eye development GO:0048749 2 0.033
Fly
ventral spinal cord interneuron differentiation GO:0021514 12 0.033
developmental cell growth GO:0048588 52 0.033
mesodermal cell fate specification GO:0007501 12 0.033
hepatocyte proliferation GO:0072574 2 0.033
digestive system development GO:0055123 289 0.033
Zebrafish
negative regulation of neuron projection development GO:0010977 9 0.032
neuromuscular process GO:0050905 7 0.032
response to chemical GO:0042221 320 0.032
Mouse
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.032
somatic stem cell maintenance GO:0035019 1 0.032
gastrulation GO:0007369 208 0.032
Zebrafish
negative regulation of reproductive process GO:2000242 3 0.032
nephron development GO:0072006 31 0.031
positive regulation of neural precursor cell proliferation GO:2000179 1 0.031
single organism biosynthetic process GO:0044711 71 0.031
photoreceptor cell fate commitment GO:0046552 1 0.031
Fly
embryonic epithelial tube formation GO:0001838 17 0.031
Zebrafish
response to fibroblast growth factor GO:0071774 22 0.031
regulation of epithelial cell differentiation GO:0030856 7 0.030
Zebrafish Mouse
dorsal ventral axis specification GO:0009950 14 0.030
regulation of transcription involved in cell fate commitment GO:0060850 1 0.030
nephron epithelium development GO:0072009 16 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
regulation of wnt signaling pathway GO:0030111 53 0.030
spinal cord patterning GO:0021511 6 0.030
endocardial cushion development GO:0003197 6 0.030
regulation of synaptic plasticity GO:0048167 1 0.030
protein modification process GO:0036211 100 0.029
cognition GO:0050890 1 0.029
wnt signaling pathway GO:0016055 80 0.029
negative regulation of rna biosynthetic process GO:1902679 45 0.029

atoh1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.190
nervous system disease DOID:863 0 0.080
auditory system disease DOID:2742 0 0.061
nonsyndromic deafness DOID:0050563 0 0.061
sensory system disease DOID:0050155 0 0.061
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.047
musculoskeletal system disease DOID:17 0 0.031