Danio rerio

15 known processes

aurka

aurora kinase A

(Aliases: zgc:100912)

aurka biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome cycle GO:0007098 1 0.560
Mouse
neuron differentiation GO:0030182 353 0.533
Mouse
spindle assembly GO:0051225 2 0.505
Yeast Mouse Worm
microtubule organizing center organization GO:0031023 1 0.416
Mouse
signal transduction GO:0007165 455 0.387
cellular component morphogenesis GO:0032989 336 0.277
Mouse
macromolecular complex subunit organization GO:0043933 74 0.270
Human Yeast Mouse Worm
digestive system development GO:0055123 289 0.262
meiosis ii GO:0007135 1 0.260
Yeast
cell morphogenesis GO:0000902 289 0.256
Mouse
spindle assembly involved in meiosis GO:0090306 1 0.253
Mouse
meiotic nuclear division GO:0007126 4 0.229
Yeast Mouse Worm
mitotic nuclear division GO:0007067 18 0.222
organelle assembly GO:0070925 110 0.221
Yeast Mouse Worm
regulation of chromosome segregation GO:0051983 1 0.211
generation of neurons GO:0048699 385 0.200
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.200
Human Yeast Mouse Rat Worm
negative regulation of cellular process GO:0048523 283 0.193
Human Yeast Mouse
protein complex subunit organization GO:0071822 46 0.183
Human Yeast Mouse Worm
cellular protein modification process GO:0006464 100 0.176
Human Yeast Mouse Rat Worm
organelle organization GO:0006996 227 0.169
regulation of cell communication GO:0010646 232 0.166
cell cycle GO:0007049 93 0.162
regulation of protein catabolic process GO:0042176 1 0.161
Mouse
mitotic cell cycle embryonic GO:0045448 2 0.160
negative regulation of cell communication GO:0010648 96 0.155
positive regulation of biological process GO:0048518 253 0.151
Yeast Mouse
regulation of signal transduction GO:0009966 225 0.145
female meiotic division GO:0007143 2 0.139
Mouse
oocyte maturation GO:0001556 4 0.135
Mouse
cytokinesis GO:0000910 3 0.132
Yeast Zebrafish Worm
protein modification process GO:0036211 100 0.129
Human Yeast Mouse Rat Worm
regulation of metabolic process GO:0019222 359 0.127
Human Mouse
positive regulation of cellular process GO:0048522 201 0.125
Yeast Mouse
negative regulation of biological process GO:0048519 304 0.119
Human Yeast Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.116
Human Mouse
positive regulation of metabolic process GO:0009893 108 0.110
Mouse
meiosis i GO:0007127 1 0.107
Yeast Mouse
male meiosis GO:0007140 2 0.106
spindle assembly involved in mitosis GO:0090307 1 0.104
Yeast Worm
microtubule based process GO:0007017 60 0.103
Human Yeast Zebrafish Mouse Worm
regulation of synapse organization GO:0050807 3 0.101
negative regulation of mitosis GO:0045839 3 0.099
regulation of primary metabolic process GO:0080090 311 0.099
Mouse
macromolecule modification GO:0043412 111 0.095
Human Yeast Mouse Rat Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.094
Mouse
multicellular organism growth GO:0035264 4 0.094
response to stress GO:0006950 263 0.093
negative regulation of signal transduction GO:0009968 94 0.092
cellular protein catabolic process GO:0044257 4 0.090
Mouse
intracellular signal transduction GO:0035556 85 0.086
cytokinetic process GO:0032506 2 0.086
Zebrafish Worm
death GO:0016265 121 0.085
Mouse
regulation of cellular metabolic process GO:0031323 320 0.083
Mouse
protein localization to nucleus GO:0034504 3 0.083
Yeast
apoptotic process GO:0006915 116 0.083
Mouse
phagocytosis GO:0006909 3 0.080
mitotic spindle organization GO:0007052 5 0.079
Yeast Mouse Worm
specification of symmetry GO:0009799 204 0.079
negative regulation of cell death GO:0060548 60 0.078
Mouse
phosphorus metabolic process GO:0006793 109 0.078
Human Yeast Mouse Rat Worm
aromatic compound biosynthetic process GO:0019438 217 0.077
negative regulation of response to stimulus GO:0048585 104 0.077
microtubule polymerization or depolymerization GO:0031109 3 0.077
Human
establishment of protein localization to organelle GO:0072594 4 0.076
Yeast
regulation of meiotic cell cycle GO:0051445 1 0.075
regulation of gene expression GO:0010468 265 0.074
Human
positive regulation of cell cycle GO:0045787 3 0.072
Yeast
meiotic chromosome segregation GO:0045132 3 0.072
Yeast
sister chromatid segregation GO:0000819 6 0.071
Yeast
organelle localization GO:0051640 49 0.071
Mouse
cell cycle g2 m phase transition GO:0044839 4 0.070
heterocycle metabolic process GO:0046483 290 0.068
Worm
cleavage furrow formation GO:0036089 2 0.067
Zebrafish
cellular component assembly GO:0022607 170 0.066
Yeast Mouse Worm
regulation of binding GO:0051098 3 0.066
Human
gene expression GO:0010467 252 0.065
Human
negative regulation of nuclear division GO:0051784 3 0.065
cell cycle process GO:0022402 53 0.064
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.063
Yeast Worm
centrosome organization GO:0051297 1 0.063
Mouse
larval development GO:0002164 2 0.062
protein metabolic process GO:0019538 183 0.059
Human Yeast Mouse Rat Worm
regulation of microtubule cytoskeleton organization GO:0070507 3 0.059
Human Yeast
cellular biosynthetic process GO:0044249 286 0.059
organic substance biosynthetic process GO:1901576 289 0.057
neuron development GO:0048666 262 0.057
Mouse
microtubule based movement GO:0007018 33 0.057
neuron projection development GO:0031175 180 0.057
Mouse
multi organism process GO:0051704 134 0.055
Mouse
mitotic sister chromatid segregation GO:0000070 6 0.055
regulation of nucleotide catabolic process GO:0030811 2 0.054
heart development GO:0007507 313 0.052
positive regulation of cellular catabolic process GO:0031331 3 0.052
Mouse
cytoskeleton dependent cytokinesis GO:0061640 3 0.052
Zebrafish Worm
negative regulation of catabolic process GO:0009895 3 0.052
digestive tract development GO:0048565 265 0.051
embryonic organ development GO:0048568 381 0.051
chromosome organization GO:0051276 31 0.051
Yeast Mouse Worm
meiotic spindle organization GO:0000212 1 0.051
Mouse
negative regulation of cell cycle phase transition GO:1901988 5 0.050
Yeast
organic substance catabolic process GO:1901575 28 0.049
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.048
reciprocal dna recombination GO:0035825 1 0.048
regulation of protein import into nucleus GO:0042306 2 0.048
Yeast
regulation of cellular component organization GO:0051128 86 0.048
Human Yeast
growth GO:0040007 174 0.047
Mouse
neuroblast proliferation GO:0007405 2 0.047
g2 m transition of mitotic cell cycle GO:0000086 4 0.046
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.046
meiotic cell cycle process GO:1903046 3 0.046
Yeast Mouse
negative regulation of signaling GO:0023057 96 0.046
cell death GO:0008219 121 0.046
Mouse
chromosome segregation GO:0007059 12 0.045
Yeast Zebrafish Worm
regulation of protein localization to nucleus GO:1900180 2 0.045
Yeast
regulation of cell cycle GO:0051726 52 0.045
Human Yeast Mouse Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.044
mitotic dna integrity checkpoint GO:0044774 4 0.043
Yeast
oocyte development GO:0048599 14 0.043
Mouse
response to abiotic stimulus GO:0009628 122 0.043
guanosine containing compound catabolic process GO:1901069 2 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
positive regulation of chromosome segregation GO:0051984 1 0.042
regulation of apoptotic process GO:0042981 98 0.042
Mouse
determination of left right symmetry GO:0007368 179 0.042
vasculature development GO:0001944 278 0.041
small molecule metabolic process GO:0044281 77 0.041
macromolecule biosynthetic process GO:0009059 227 0.041
programmed cell death GO:0012501 119 0.040
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.040
Mouse
modification dependent protein catabolic process GO:0019941 3 0.040
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.040
protein polymerization GO:0051258 4 0.039
negative regulation of programmed cell death GO:0043069 58 0.039
Mouse
regulation of response to stimulus GO:0048583 269 0.039
gastrulation GO:0007369 208 0.039
actin cytoskeleton organization GO:0030036 63 0.039
nucleic acid templated transcription GO:0097659 181 0.038
catabolic process GO:0009056 32 0.038
Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
nuclear envelope organization GO:0006998 2 0.037
sensory organ morphogenesis GO:0090596 200 0.036
establishment of organelle localization GO:0051656 45 0.036
mitotic cell cycle checkpoint GO:0007093 5 0.036
Yeast
regulation of signaling GO:0023051 235 0.036
tube morphogenesis GO:0035239 349 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.035
stem cell proliferation GO:0072089 4 0.035
oxoacid metabolic process GO:0043436 31 0.035
histone phosphorylation GO:0016572 2 0.035
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.035
regulation of programmed cell death GO:0043067 101 0.035
Mouse
regulation of cell differentiation GO:0045595 142 0.034
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.034
single organism metabolic process GO:0044710 217 0.033
Mouse Worm
gtp catabolic process GO:0006184 2 0.033
cell surface receptor signaling pathway GO:0007166 325 0.033
microtubule cytoskeleton organization GO:0000226 33 0.033
Human Yeast Zebrafish Mouse Worm
regulation of synapse structure and activity GO:0050803 5 0.033
phosphate containing compound metabolic process GO:0006796 108 0.032
Human Yeast Mouse Rat Worm
single organism organelle organization GO:1902589 199 0.032
regulation of nucleocytoplasmic transport GO:0046822 2 0.032
Yeast
nucleic acid metabolic process GO:0090304 244 0.032
Worm
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.031
multicellular organismal reproductive process GO:0048609 35 0.031
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.030
cellular component biogenesis GO:0044085 178 0.030
Yeast Mouse Worm
nucleoside phosphate metabolic process GO:0006753 28 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
regulation of nucleoside metabolic process GO:0009118 2 0.029
neuron projection morphogenesis GO:0048812 161 0.029
Mouse
morphogenesis of an epithelium GO:0002009 333 0.028
actin filament based process GO:0030029 64 0.028
mitotic cell cycle process GO:1903047 48 0.027
spindle assembly involved in female meiosis GO:0007056 1 0.027
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.027
mitotic metaphase plate congression GO:0007080 1 0.027
female meiosis ii GO:0007147 1 0.027
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
cytoskeleton organization GO:0007010 96 0.027
Human Yeast Zebrafish Mouse Worm
microtubule depolymerization GO:0007019 1 0.026
Human
positive regulation of cell division GO:0051781 2 0.026
cellular protein metabolic process GO:0044267 129 0.026
Human Yeast Mouse Rat Worm
regulation of protein ubiquitination GO:0031396 3 0.026
nitrogen compound metabolic process GO:0006807 319 0.025
Worm
regulation of cellular protein catabolic process GO:1903362 1 0.025
Mouse
homologous chromosome segregation GO:0045143 1 0.025
Yeast
cellular aromatic compound metabolic process GO:0006725 295 0.025
Worm
guanosine containing compound metabolic process GO:1901068 4 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.025
Mouse
dorsal ventral pattern formation GO:0009953 125 0.025
negative regulation of chromosome organization GO:2001251 1 0.025
germ cell development GO:0007281 22 0.024
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
regulation of intracellular signal transduction GO:1902531 57 0.023
transcription dna templated GO:0006351 181 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
smad protein complex assembly GO:0007183 1 0.023
biosynthetic process GO:0009058 294 0.023
positive regulation of histone modification GO:0031058 1 0.023
mitotic cytokinesis GO:0000281 3 0.023
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.022
convergent extension GO:0060026 118 0.022
positive regulation of chromosome organization GO:2001252 1 0.022
organelle fission GO:0048285 23 0.022
digestive tract morphogenesis GO:0048546 231 0.022
cell projection organization GO:0030030 284 0.022
Mouse
response to fibroblast growth factor GO:0071774 22 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
Mouse
cellular response to chemical stimulus GO:0070887 157 0.022
positive regulation of muscle organ development GO:0048636 1 0.022
protein import into nucleus GO:0006606 3 0.021
Yeast
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
response to organic substance GO:0010033 153 0.021
Rat
oocyte differentiation GO:0009994 14 0.021
Mouse
regulation of protein targeting GO:1903533 2 0.021
Yeast
regulation of cell death GO:0010941 103 0.021
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.021
response to chemical GO:0042221 320 0.021
Rat
regulation of heart growth GO:0060420 2 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
Mouse
regulation of phosphate metabolic process GO:0019220 43 0.020
regulation of catalytic activity GO:0050790 55 0.020
mitotic dna damage checkpoint GO:0044773 4 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
Mouse
maintenance of location GO:0051235 4 0.020
Yeast
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
Mouse
protein targeting to nucleus GO:0044744 3 0.020
Yeast
microtubule polymerization GO:0046785 2 0.020
cellular response to stress GO:0033554 62 0.019
positive regulation of catabolic process GO:0009896 4 0.019
Mouse
amine metabolic process GO:0009308 2 0.019
cellular component movement GO:0006928 335 0.019
chromosome localization GO:0050000 2 0.019
single organism nuclear import GO:1902593 3 0.019
Yeast
regulation of establishment of protein localization GO:0070201 4 0.018
Yeast
nuclear migration GO:0007097 3 0.018
spermatid development GO:0007286 2 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
nuclear transport GO:0051169 4 0.018
Yeast
regulation of cardiac muscle tissue development GO:0055024 1 0.018
cellular amine metabolic process GO:0044106 2 0.018
single organism reproductive process GO:0044702 40 0.018
Mouse Worm
regulation of oocyte development GO:0060281 3 0.017
Mouse
stem cell maintenance GO:0019827 4 0.017
organic acid metabolic process GO:0006082 31 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
Yeast
muscle structure development GO:0061061 196 0.017
regulation of protein metabolic process GO:0051246 56 0.017
Mouse
wnt signaling pathway GO:0016055 80 0.017
cellular response to organic substance GO:0071310 105 0.016
regulation of rna metabolic process GO:0051252 224 0.016
nuclear import GO:0051170 3 0.016
Yeast
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
negative regulation of cell cycle process GO:0010948 9 0.016
Yeast Mouse
angiogenesis GO:0001525 158 0.016
determination of bilateral symmetry GO:0009855 204 0.016
cell cycle phase transition GO:0044770 9 0.016
Yeast
organelle fusion GO:0048284 3 0.016
histone h3 k4 methylation GO:0051568 2 0.016
positive regulation of transport GO:0051050 2 0.016
negative regulation of developmental process GO:0051093 65 0.016
protein import GO:0017038 3 0.015
Yeast
locomotion GO:0040011 313 0.015
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.015
regulation of gtpase activity GO:0043087 2 0.015
mitotic cell cycle phase transition GO:0044772 9 0.015
Yeast
cell division GO:0051301 20 0.015
Yeast Zebrafish Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
regulation of dendrite development GO:0050773 3 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
Mouse
fertilization GO:0009566 3 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
regulation of nervous system development GO:0051960 90 0.014
regulation of molecular function GO:0065009 70 0.014
Human
apoptotic signaling pathway GO:0097190 23 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
Yeast
axonogenesis GO:0007409 152 0.014
pancreas development GO:0031016 84 0.014
mitotic cell cycle GO:0000278 64 0.013
phosphorylation GO:0016310 69 0.013
Human Yeast Mouse Rat Worm
regulation of mitotic cell cycle GO:0007346 25 0.013
Yeast
regulation of histone h3 k9 methylation GO:0051570 2 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
Worm
cellular response to growth factor stimulus GO:0071363 39 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
Worm
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
gtp metabolic process GO:0046039 4 0.013
protein phosphorylation GO:0006468 47 0.013
Human Yeast Mouse Rat Worm
carboxylic acid metabolic process GO:0019752 22 0.013
negative regulation of protein transport GO:0051224 3 0.013
Yeast
establishment of localization in cell GO:0051649 77 0.013
Yeast
regulation of skeletal muscle fiber development GO:0048742 2 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
cell cycle checkpoint GO:0000075 7 0.012
Yeast Mouse
regulation of cell shape GO:0008360 1 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
Yeast
regulation of intracellular protein transport GO:0033157 3 0.012
Yeast
stem cell division GO:0017145 1 0.012
peptidyl threonine modification GO:0018210 1 0.012
Worm
positive regulation of proteolysis GO:0045862 10 0.012
Mouse
aging GO:0007568 2 0.012
spindle organization GO:0007051 5 0.012
Human Yeast Mouse Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.012
Worm
peptidyl serine modification GO:0018209 2 0.012
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
cell cycle arrest GO:0007050 1 0.012
regulation of proteolysis GO:0030162 24 0.012
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.012
Worm
purine nucleotide metabolic process GO:0006163 27 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
rna biosynthetic process GO:0032774 181 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
regulation of dna replication GO:0006275 3 0.011
regulation of establishment of planar polarity GO:0090175 4 0.011
regulation of organelle organization GO:0033043 29 0.011
Human Yeast
organonitrogen compound metabolic process GO:1901564 74 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
Worm
female meiosis chromosome segregation GO:0016321 1 0.011
cell motility GO:0048870 244 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
Mouse
chromatin modification GO:0016568 21 0.011
Mouse
response to radiation GO:0009314 51 0.011
developmental growth GO:0048589 166 0.011
Mouse
negative regulation of apoptotic process GO:0043066 55 0.010
Mouse
positive regulation of catalytic activity GO:0043085 25 0.010
regulation of cellular protein metabolic process GO:0032268 52 0.010
Mouse
peptidyl serine phosphorylation GO:0018105 1 0.010
Mouse Worm
regulation of microtubule depolymerization GO:0031114 1 0.010
Human
positive regulation of developmental process GO:0051094 50 0.010
Mouse
positive regulation of cellular protein metabolic process GO:0032270 22 0.010
Mouse
nucleotide metabolic process GO:0009117 28 0.010
chromosome organization involved in meiosis GO:0070192 1 0.010
Yeast
transport GO:0006810 220 0.010
Yeast
negative regulation of protein localization to nucleus GO:1900181 2 0.010
Yeast

aurka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.010
disease of anatomical entity DOID:7 0 0.010
bone marrow disease DOID:4961 0 0.010
hematopoietic system disease DOID:74 0 0.010