Danio rerio

0 known processes

aven

apoptosis, caspase activation inhibitor

(Aliases: si:ch211-150c22.4,wu:fc08c09,zgc:136239)

aven biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.105
regulation of cellular biosynthetic process GO:0031326 245 0.069
cellular macromolecule metabolic process GO:0044260 391 0.066
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.064
cellular biosynthetic process GO:0044249 286 0.060
cellular protein catabolic process GO:0044257 4 0.060
regulation of biosynthetic process GO:0009889 250 0.056
multicellular organism growth GO:0035264 4 0.055
aging GO:0007568 2 0.053
regulation of macromolecule biosynthetic process GO:0010556 225 0.046
organic substance biosynthetic process GO:1901576 289 0.046
regulation of primary metabolic process GO:0080090 311 0.044
positive regulation of cell cycle GO:0045787 3 0.042
protein localization to plasma membrane GO:0072659 1 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
nitrogen compound metabolic process GO:0006807 319 0.039
protein localization to nucleus GO:0034504 3 0.038
aromatic compound biosynthetic process GO:0019438 217 0.037
regulation of nitrogen compound metabolic process GO:0051171 251 0.036
regulation of metabolic process GO:0019222 359 0.036
proteasomal protein catabolic process GO:0010498 2 0.035
regulation of establishment of protein localization GO:0070201 4 0.035
heterocycle biosynthetic process GO:0018130 215 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.033
negative regulation of biological process GO:0048519 304 0.033
positive regulation of transport GO:0051050 2 0.032
protein targeting to nucleus GO:0044744 3 0.032
heterocycle metabolic process GO:0046483 290 0.032
protein import into nucleus GO:0006606 3 0.031
regulation of macromolecule metabolic process GO:0060255 317 0.030
mitochondrion organization GO:0007005 4 0.030
regulation of cellular metabolic process GO:0031323 320 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
biosynthetic process GO:0009058 294 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
protein import GO:0017038 3 0.028
macromolecule modification GO:0043412 111 0.028
response to drug GO:0042493 3 0.028
regulation of binding GO:0051098 3 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.028
meiotic nuclear division GO:0007126 4 0.028
nuclear transport GO:0051169 4 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
protein metabolic process GO:0019538 183 0.027
regulation of protein transport GO:0051223 3 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
nucleic acid templated transcription GO:0097659 181 0.026
g1 s transition of mitotic cell cycle GO:0000082 1 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
transcription dna templated GO:0006351 181 0.025
macromolecule biosynthetic process GO:0009059 227 0.025
neuron development GO:0048666 262 0.025
signal transduction GO:0007165 455 0.025
gene expression GO:0010467 252 0.025
single organism nuclear import GO:1902593 3 0.025
nuclear import GO:0051170 3 0.024
growth GO:0040007 174 0.024
nucleic acid metabolic process GO:0090304 244 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of cell activation GO:0050865 1 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
amine metabolic process GO:0009308 2 0.023
cellular protein metabolic process GO:0044267 129 0.023
gtp catabolic process GO:0006184 2 0.023
cellular amine metabolic process GO:0044106 2 0.023
response to nutrient GO:0007584 3 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
immune system process GO:0002376 241 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
response to monosaccharide GO:0034284 3 0.023
regulation of cellular component organization GO:0051128 86 0.023
determination of bilateral symmetry GO:0009855 204 0.023
transport GO:0006810 220 0.023
epithelial tube morphogenesis GO:0060562 148 0.022
regulation of protein ubiquitination GO:0031396 3 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
positive regulation of cell activation GO:0050867 1 0.022
negative regulation of cellular process GO:0048523 283 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
gtp metabolic process GO:0046039 4 0.022
cellular component movement GO:0006928 335 0.022
response to external stimulus GO:0009605 264 0.022
heart development GO:0007507 313 0.022
single organism metabolic process GO:0044710 217 0.022
liver development GO:0001889 96 0.022
organonitrogen compound metabolic process GO:1901564 74 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
membrane lipid biosynthetic process GO:0046467 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
regulation of protein targeting GO:1903533 2 0.021
regulation of chromosome segregation GO:0051983 1 0.021
specification of symmetry GO:0009799 204 0.021
response to hexose GO:0009746 3 0.021
organism emergence from protective structure GO:0071684 4 0.021
apoptotic process GO:0006915 116 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
regulation of synapse organization GO:0050807 3 0.020
cellular ketone metabolic process GO:0042180 11 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
vasculature development GO:0001944 278 0.020
embryonic organ development GO:0048568 381 0.020
regulation of synapse assembly GO:0051963 3 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
protein modification process GO:0036211 100 0.020
regulation of response to stimulus GO:0048583 269 0.020
cellular amino acid metabolic process GO:0006520 7 0.019
rna metabolic process GO:0016070 219 0.019
response to carbohydrate GO:0009743 3 0.019
peptidyl threonine modification GO:0018210 1 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
phagocytosis GO:0006909 3 0.019
peptidyl threonine phosphorylation GO:0018107 1 0.019
maintenance of location GO:0051235 4 0.019
regulation of reproductive process GO:2000241 4 0.019
stem cell maintenance GO:0019827 4 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
leukocyte proliferation GO:0070661 1 0.019
determination of left right symmetry GO:0007368 179 0.019
regulation of apoptotic process GO:0042981 98 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
protein dephosphorylation GO:0006470 3 0.019
tube morphogenesis GO:0035239 349 0.018
regulation of developmental process GO:0050793 247 0.018
cellular protein modification process GO:0006464 100 0.018
immune system development GO:0002520 191 0.018
glycolipid biosynthetic process GO:0009247 1 0.018
response to corticosteroid GO:0031960 1 0.018
cell motility GO:0048870 244 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
sensory organ development GO:0007423 393 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of cell communication GO:0010646 232 0.018
developmental growth GO:0048589 166 0.018
heart looping GO:0001947 94 0.018
central nervous system development GO:0007417 387 0.018
autophagy GO:0006914 4 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
membrane fusion GO:0061025 2 0.017
response to glucose GO:0009749 3 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
regulation of inflammatory response GO:0050727 2 0.017
protein stabilization GO:0050821 2 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
regulation of response to extracellular stimulus GO:0032104 1 0.017
single organism membrane fusion GO:0044801 2 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
regulation of rna metabolic process GO:0051252 224 0.016
fertilization GO:0009566 3 0.016
adult behavior GO:0030534 2 0.016
brain development GO:0007420 293 0.016
b cell activation GO:0042113 2 0.016
rna biosynthetic process GO:0032774 181 0.016
regulation of gene expression GO:0010468 265 0.016
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.016
positive regulation of epithelial cell proliferation GO:0050679 1 0.016
locomotion GO:0040011 313 0.016
regulation of cell death GO:0010941 103 0.016
protein polyubiquitination GO:0000209 4 0.016
regulation of protein catabolic process GO:0042176 1 0.016
regeneration GO:0031099 91 0.016
meiotic cell cycle process GO:1903046 3 0.016
regulation of cytokine production GO:0001817 3 0.016
regulation of transcription dna templated GO:0006355 213 0.016
rna localization GO:0006403 4 0.016
positive regulation of secretion GO:0051047 1 0.016
regulation of response to cytokine stimulus GO:0060759 3 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
meiotic chromosome segregation GO:0045132 3 0.015
regulation of signal transduction GO:0009966 225 0.015
positive regulation of cellular process GO:0048522 201 0.015
programmed cell death GO:0012501 119 0.015
stem cell proliferation GO:0072089 4 0.015
cortical actin cytoskeleton organization GO:0030866 1 0.015
positive regulation of blood circulation GO:1903524 2 0.015
cellular localization GO:0051641 97 0.015
head development GO:0060322 303 0.015
cortical cytoskeleton organization GO:0030865 1 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
positive regulation of biological process GO:0048518 253 0.015
single organism localization GO:1902578 225 0.015
response to stress GO:0006950 263 0.015
eye development GO:0001654 277 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
cell morphogenesis GO:0000902 289 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
lipid storage GO:0019915 1 0.014
sleep GO:0030431 1 0.014
lymphocyte proliferation GO:0046651 1 0.014
regulation of cell shape GO:0008360 1 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
camera type eye development GO:0043010 222 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
regulation of translational initiation GO:0006446 1 0.014
regulation of jak stat cascade GO:0046425 3 0.014
negative regulation of metabolic process GO:0009892 86 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
generation of neurons GO:0048699 385 0.014
positive regulation of cytokine production GO:0001819 2 0.014
organelle organization GO:0006996 227 0.014
embryonic heart tube development GO:0035050 133 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
positive regulation of leukocyte differentiation GO:1902107 1 0.014
cellular response to radiation GO:0071478 4 0.014
spindle assembly GO:0051225 2 0.014
response to chemical GO:0042221 320 0.014
positive regulation of translation GO:0045727 1 0.014
female gonad development GO:0008585 4 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
organelle fusion GO:0048284 3 0.013
cognition GO:0050890 1 0.013
cell matrix adhesion GO:0007160 4 0.013
cellular component morphogenesis GO:0032989 336 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
carbohydrate homeostasis GO:0033500 1 0.013
neurotransmitter secretion GO:0007269 2 0.013
cell substrate adhesion GO:0031589 4 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
cell migration GO:0016477 237 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
regulation of autophagy GO:0010506 3 0.013
positive regulation of histone modification GO:0031058 1 0.013
cellular response to starvation GO:0009267 1 0.013
tube closure GO:0060606 1 0.013
mitotic cell cycle embryonic GO:0045448 2 0.013
axon development GO:0061564 166 0.013
primary neural tube formation GO:0014020 1 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
glycerolipid biosynthetic process GO:0045017 1 0.013
cell aging GO:0007569 2 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.012
synaptic vesicle localization GO:0097479 1 0.012
peptidyl serine modification GO:0018209 2 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
mononuclear cell proliferation GO:0032943 1 0.012
female sex differentiation GO:0046660 4 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
response to uv GO:0009411 3 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
establishment of localization GO:0051234 244 0.012
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
regulation of protein binding GO:0043393 3 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
b cell differentiation GO:0030183 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
regulation of programmed cell death GO:0043067 101 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
regulation of signaling GO:0023051 235 0.012
negative regulation of catabolic process GO:0009895 3 0.012
somatic muscle development GO:0007525 4 0.012
protein acylation GO:0043543 3 0.012
glucose homeostasis GO:0042593 1 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
macroautophagy GO:0016236 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
phosphorylation GO:0016310 69 0.012
cell death GO:0008219 121 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
regulation of protein complex assembly GO:0043254 3 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
mitotic cell cycle GO:0000278 64 0.011
organelle localization GO:0051640 49 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
heart morphogenesis GO:0003007 156 0.011
phosphorus metabolic process GO:0006793 109 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
atp catabolic process GO:0006200 4 0.011
death GO:0016265 121 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
hemopoiesis GO:0030097 183 0.011
chromosome organization involved in meiosis GO:0070192 1 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
synaptic target recognition GO:0008039 1 0.011
nuclear export GO:0051168 1 0.011
response to organic substance GO:0010033 153 0.011
negative regulation of neuron projection regeneration GO:0070571 4 0.011
secondary metabolic process GO:0019748 3 0.011
chemotaxis GO:0006935 104 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
negative regulation of defense response GO:0031348 2 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
somatic stem cell maintenance GO:0035019 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
negative regulation of signaling GO:0023057 96 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
neurotransmitter transport GO:0006836 2 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
response to amino acid GO:0043200 2 0.011
system process GO:0003008 185 0.011
cell projection organization GO:0030030 284 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
response to vitamin GO:0033273 3 0.011
tissue remodeling GO:0048771 4 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
positive regulation of lipid metabolic process GO:0045834 1 0.010
hormone transport GO:0009914 2 0.010
regulation of blood pressure GO:0008217 1 0.010
positive regulation of protein kinase b signaling GO:0051897 1 0.010
protein acetylation GO:0006473 2 0.010
blood vessel development GO:0001568 246 0.010
cytokinesis GO:0000910 3 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
exocytosis GO:0006887 1 0.010
regulation of protein localization to plasma membrane GO:1903076 1 0.010
neuroblast proliferation GO:0007405 2 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
nuclear envelope organization GO:0006998 2 0.010
endosomal transport GO:0016197 2 0.010
hormone secretion GO:0046879 2 0.010
chordate embryonic development GO:0043009 271 0.010
regulation of organelle assembly GO:1902115 4 0.010
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.010
ameboidal type cell migration GO:0001667 143 0.010
long chain fatty acid metabolic process GO:0001676 1 0.010
negative chemotaxis GO:0050919 1 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
positive regulation of metabolic process GO:0009893 108 0.010

aven disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
cardiovascular system disease DOID:1287 0 0.014
nervous system disease DOID:863 0 0.013
sensory system disease DOID:0050155 0 0.011
musculoskeletal system disease DOID:17 0 0.011