Danio rerio

10 known processes

axin2

axin 2 (conductin, axil)

(Aliases: axil,wu:fb37c08,zgc:111942)

axin2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 274 0.954
sensory organ development GO:0007423 393 0.945
Zebrafish
digestive system development GO:0055123 289 0.936
central nervous system development GO:0007417 387 0.910
Zebrafish
forebrain development GO:0030900 96 0.909
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.906
Human Zebrafish Rat
head development GO:0060322 303 0.891
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.846
segmentation GO:0035282 97 0.827
Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.824
Zebrafish
canonical wnt signaling pathway GO:0060070 48 0.820
Human Zebrafish Worm
cellular component movement GO:0006928 335 0.815
Worm
gene expression GO:0010467 252 0.804
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.798
rna biosynthetic process GO:0032774 181 0.791
posterior lateral line development GO:0048916 38 0.772
generation of neurons GO:0048699 385 0.762
Zebrafish Worm
brain development GO:0007420 293 0.761
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.753
Human Zebrafish Mouse Rat Worm Fly
regulation of metabolic process GO:0019222 359 0.732
Human Zebrafish Rat
digestive tract development GO:0048565 265 0.705
transcription dna templated GO:0006351 181 0.699
regulation of canonical wnt signaling pathway GO:0060828 34 0.690
Human Zebrafish
regulation of gene expression GO:0010468 265 0.688
Human
signal transduction GO:0007165 455 0.681
Human Zebrafish Mouse Rat Worm Fly
connective tissue development GO:0061448 99 0.675
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.674
tube morphogenesis GO:0035239 349 0.668
embryonic organ development GO:0048568 381 0.657
Zebrafish
neuron development GO:0048666 262 0.655
Worm
single organism organelle organization GO:1902589 199 0.647
Human Mouse Worm
biosynthetic process GO:0009058 294 0.645
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.643
neuron differentiation GO:0030182 353 0.619
Zebrafish Worm
radial glial cell differentiation GO:0060019 2 0.617
regulation of transcription dna templated GO:0006355 213 0.615
heterocycle biosynthetic process GO:0018130 215 0.610
camera type eye development GO:0043010 222 0.596
somitogenesis GO:0001756 87 0.594
Zebrafish Mouse
hypothalamus cell differentiation GO:0021979 4 0.575
gastrulation GO:0007369 208 0.565
hepaticobiliary system development GO:0061008 98 0.559
regulation of nucleic acid templated transcription GO:1903506 213 0.559
localization of cell GO:0051674 244 0.556
Worm
regulation of stem cell proliferation GO:0072091 2 0.554
regulation of response to stimulus GO:0048583 269 0.547
Human Zebrafish Mouse Rat Worm Fly
positive regulation of gene expression GO:0010628 71 0.547
digestive tract morphogenesis GO:0048546 231 0.543
wnt signaling pathway GO:0016055 80 0.526
Human Zebrafish Mouse Rat Worm Fly
anterior posterior pattern specification GO:0009952 152 0.507
Zebrafish Mouse Worm
chordate embryonic development GO:0043009 271 0.505
Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.496
Human Zebrafish Mouse Rat Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.490
cell proliferation in forebrain GO:0021846 3 0.490
regulation of macromolecule metabolic process GO:0060255 317 0.468
Human Zebrafish Rat
macromolecule biosynthetic process GO:0009059 227 0.460
posterior lateral line system development GO:0048915 46 0.456
organic substance biosynthetic process GO:1901576 289 0.452
cellular biosynthetic process GO:0044249 286 0.451
cellular macromolecule metabolic process GO:0044260 391 0.449
Human Zebrafish Rat
eye development GO:0001654 277 0.447
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.447
Human
positive regulation of map kinase activity GO:0043406 3 0.443
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.424
lateral line development GO:0048882 66 0.424
neuroblast proliferation GO:0007405 2 0.413
regulation of biosynthetic process GO:0009889 250 0.412
immune system development GO:0002520 191 0.398
regulation of biological quality GO:0065008 263 0.396
Human
heart looping GO:0001947 94 0.394
cellular nitrogen compound metabolic process GO:0034641 290 0.392
Human
muscle cell differentiation GO:0042692 139 0.383
Zebrafish
skeletal system development GO:0001501 181 0.376
Mouse
regulation of establishment of protein localization GO:0070201 4 0.359
Human
cell proliferation in dorsal spinal cord GO:0010456 2 0.357
regulation of signaling GO:0023051 235 0.350
Human Zebrafish Mouse Rat Worm Fly
heart morphogenesis GO:0003007 156 0.339
Mouse
muscle tissue development GO:0060537 110 0.336
neural tube development GO:0021915 62 0.335
notch signaling pathway GO:0007219 35 0.334
positive regulation of cellular biosynthetic process GO:0031328 68 0.332
olfactory lobe development GO:0021988 4 0.332
determination of left right symmetry GO:0007368 179 0.327
Zebrafish
negative regulation of cellular metabolic process GO:0031324 77 0.325
cell motility GO:0048870 244 0.315
Worm
heart development GO:0007507 313 0.314
Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.314
Human
stem cell proliferation GO:0072089 4 0.310
determination of bilateral symmetry GO:0009855 204 0.309
Zebrafish
blood vessel development GO:0001568 246 0.300
embryo development ending in birth or egg hatching GO:0009792 271 0.295
Zebrafish Mouse
positive regulation of neural precursor cell proliferation GO:2000179 1 0.293
midbrain development GO:0030901 28 0.291
morphogenesis of an epithelium GO:0002009 333 0.287
Zebrafish
hindbrain development GO:0030902 91 0.286
embryonic heart tube development GO:0035050 133 0.284
cell proliferation in midbrain GO:0033278 4 0.283
cellular macromolecule biosynthetic process GO:0034645 224 0.277
establishment of localization GO:0051234 244 0.276
Human Fly
gland development GO:0048732 143 0.275
multicellular organism growth GO:0035264 4 0.269
Worm
regulation of multicellular organismal development GO:2000026 223 0.267
Human Mouse Rat Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.264
Human Worm
embryonic heart tube morphogenesis GO:0003143 108 0.257
appendage morphogenesis GO:0035107 56 0.255
Fly
dorsal ventral pattern formation GO:0009953 125 0.254
brain morphogenesis GO:0048854 18 0.253
negative regulation of cellular process GO:0048523 283 0.242
Human Zebrafish Mouse Rat Worm Fly
rna metabolic process GO:0016070 219 0.242
regulation of rna metabolic process GO:0051252 224 0.237
blood vessel morphogenesis GO:0048514 216 0.232
regulation of anatomical structure morphogenesis GO:0022603 130 0.231
Human
diencephalon development GO:0021536 58 0.231
formation of primary germ layer GO:0001704 62 0.229
transcription from rna polymerase ii promoter GO:0006366 80 0.226
regulation of oligodendrocyte differentiation GO:0048713 1 0.226
regulation of developmental process GO:0050793 247 0.224
Human Mouse Rat Worm Fly
specification of symmetry GO:0009799 204 0.224
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.223
mesenchymal cell differentiation GO:0048762 87 0.220
Human
positive regulation of stem cell proliferation GO:2000648 1 0.215
mitotic cell cycle GO:0000278 64 0.215
Worm
mesoderm development GO:0007498 88 0.214
regulation of cytokine production GO:0001817 3 0.211
urogenital system development GO:0001655 97 0.211
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.208
stem cell development GO:0048864 82 0.208
Human Fly
neural precursor cell proliferation GO:0061351 20 0.206
lateral line system development GO:0048925 76 0.206
axonogenesis GO:0007409 152 0.203
Worm
regulation of cell development GO:0060284 100 0.203
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.202
Zebrafish
negative regulation of transcription dna templated GO:0045892 45 0.201
embryonic organ morphogenesis GO:0048562 274 0.200
Zebrafish
cell migration GO:0016477 237 0.200
Worm
immune system process GO:0002376 241 0.197
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.197
taxis GO:0042330 109 0.196
Worm
gliogenesis GO:0042063 45 0.193
heterocycle metabolic process GO:0046483 290 0.190
Human
ameboidal type cell migration GO:0001667 143 0.190
posterior lateral line neuromast deposition GO:0048922 5 0.189
mesoderm morphogenesis GO:0048332 51 0.189
somite development GO:0061053 96 0.188
Zebrafish Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.188
Human
regulation of cell activation GO:0050865 1 0.184
regulation of multicellular organism growth GO:0040014 4 0.181
Worm
regulation of neural precursor cell proliferation GO:2000177 3 0.180
cardiac cell fate commitment GO:0060911 1 0.180
negative regulation of metabolic process GO:0009892 86 0.178
single organism metabolic process GO:0044710 217 0.178
Human Zebrafish
lipid storage GO:0019915 1 0.177
regulation of cell differentiation GO:0045595 142 0.176
Human Mouse Worm Fly
reproductive process GO:0022414 40 0.175
Worm Fly
nuclear import GO:0051170 3 0.172
Human
protein import into nucleus GO:0006606 3 0.167
Human
negative regulation of nucleic acid templated transcription GO:1903507 45 0.167
mesenchyme development GO:0060485 127 0.166
Human
regulation of epithelial to mesenchymal transition GO:0010717 3 0.165
Human
mechanosensory lateral line system development GO:0048881 49 0.164
skeletal muscle organ development GO:0060538 78 0.163
cellular nitrogen compound biosynthetic process GO:0044271 218 0.162
dna biosynthetic process GO:0071897 3 0.162
positive regulation of rna biosynthetic process GO:1902680 57 0.162
nucleic acid metabolic process GO:0090304 244 0.159
Human
epithelial tube morphogenesis GO:0060562 148 0.158
protein localization to nucleus GO:0034504 3 0.157
Human
transport GO:0006810 220 0.157
Human Fly
nucleic acid templated transcription GO:0097659 181 0.156
regulation of nervous system development GO:0051960 90 0.154
hematopoietic or lymphoid organ development GO:0048534 191 0.153
sensory system development GO:0048880 76 0.153
protein metabolic process GO:0019538 183 0.152
Human Zebrafish Rat
regulation of rna biosynthetic process GO:2001141 213 0.152
cell projection organization GO:0030030 284 0.152
Worm
negative regulation of macromolecule metabolic process GO:0010605 76 0.151
muscle structure development GO:0061061 196 0.151
Zebrafish
axon development GO:0061564 166 0.150
Worm
intracellular receptor signaling pathway GO:0030522 30 0.149
cartilage development GO:0051216 96 0.149
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.148
response to organic substance GO:0010033 153 0.147
Rat
muscle fiber development GO:0048747 52 0.146
mesoderm formation GO:0001707 43 0.145
olfactory bulb development GO:0021772 4 0.144
chemotaxis GO:0006935 104 0.144
Worm
regulation of immune system process GO:0002682 34 0.144
response to external stimulus GO:0009605 264 0.143
Worm
defense response to other organism GO:0098542 33 0.142
nucleobase containing compound metabolic process GO:0006139 274 0.140
Human
regulation of cell communication GO:0010646 232 0.140
Human Zebrafish Mouse Rat Worm Fly
dna templated transcription initiation GO:0006352 1 0.139
retinal ganglion cell axon guidance GO:0031290 35 0.139
smoothened signaling pathway GO:0007224 30 0.137
positive regulation of biological process GO:0048518 253 0.137
Human Zebrafish Rat Worm
telencephalon development GO:0021537 14 0.136
pancreas development GO:0031016 84 0.135
larval development GO:0002164 2 0.134
Worm
eye morphogenesis GO:0048592 144 0.134
Zebrafish
protein import GO:0017038 3 0.133
Human
embryonic skeletal system morphogenesis GO:0048704 93 0.131
regulation of protein import into nucleus GO:0042306 2 0.130
Human
single organism reproductive process GO:0044702 40 0.130
Worm Fly
multi organism process GO:0051704 134 0.130
Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.128
Human
organelle organization GO:0006996 227 0.127
Human Mouse Worm
neuron projection morphogenesis GO:0048812 161 0.127
Worm
bmp signaling pathway GO:0030509 52 0.126
programmed cell death GO:0012501 119 0.126
response to other organism GO:0051707 97 0.126
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.126
Human Zebrafish
regulation of cell proliferation GO:0042127 37 0.125
Human Mouse Rat
regulation of cellular metabolic process GO:0031323 320 0.125
Human Zebrafish Rat
cilium morphogenesis GO:0060271 85 0.124
nephron tubule morphogenesis GO:0072078 1 0.124
positive regulation of transcription dna templated GO:0045893 57 0.123
developmental growth GO:0048589 166 0.122
Zebrafish Worm
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.122
embryonic camera type eye development GO:0031076 29 0.121
sexual reproduction GO:0019953 36 0.120
Fly
regulation of molecular function GO:0065009 70 0.119
Zebrafish Rat
negative regulation of protein phosphorylation GO:0001933 4 0.119
proximal distal pattern formation GO:0009954 1 0.119
liver development GO:0001889 96 0.117
neuromast deposition GO:0048885 9 0.117
carboxylic acid metabolic process GO:0019752 22 0.115
retinoic acid receptor signaling pathway GO:0048384 16 0.115
hemopoiesis GO:0030097 183 0.114
nucleocytoplasmic transport GO:0006913 4 0.114
Human
response to growth factor GO:0070848 39 0.114
catenin import into nucleus GO:0035411 2 0.114
Human
positive regulation of cellular process GO:0048522 201 0.113
Human Zebrafish Rat
cellular component biogenesis GO:0044085 178 0.113
protein targeting to nucleus GO:0044744 3 0.111
Human
embryonic limb morphogenesis GO:0030326 2 0.110
negative regulation of developmental process GO:0051093 65 0.110
Mouse Rat Worm Fly
retina development in camera type eye GO:0060041 146 0.110
macromolecule modification GO:0043412 111 0.109
Human Zebrafish Rat
cellular component morphogenesis GO:0032989 336 0.109
Human Worm
positive regulation of jun kinase activity GO:0043507 2 0.108
Zebrafish
neuron migration GO:0001764 22 0.108
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.107
positive regulation of cell communication GO:0010647 56 0.107
Zebrafish
negative regulation of wnt signaling pathway GO:0030178 30 0.107
Human Zebrafish Rat Worm Fly
cellular hormone metabolic process GO:0034754 19 0.106
camera type eye morphogenesis GO:0048593 108 0.106
regulation of glial cell differentiation GO:0045685 4 0.105
negative regulation of rna biosynthetic process GO:1902679 45 0.105
regulation of signal transduction GO:0009966 225 0.104
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular component organization GO:0051128 86 0.102
Human Mouse
oxoacid metabolic process GO:0043436 31 0.102
endoderm development GO:0007492 49 0.101
lymph vessel morphogenesis GO:0036303 25 0.100
response to chemical GO:0042221 320 0.099
Rat Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.099
Human
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.098
establishment of protein localization to organelle GO:0072594 4 0.097
Human
cellular protein metabolic process GO:0044267 129 0.096
Human Zebrafish Rat
limbic system development GO:0021761 16 0.096
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.095
regulation of bmp signaling pathway GO:0030510 39 0.095
cell fate specification GO:0001708 68 0.094
Worm
cell projection morphogenesis GO:0048858 244 0.094
Worm
regulation of apoptotic process GO:0042981 98 0.093
defense response to bacterium GO:0042742 22 0.093
regulation of multicellular organismal process GO:0051239 277 0.092
Human Mouse Rat Worm
primary neural tube formation GO:0014020 1 0.092
kidney development GO:0001822 92 0.092
apoptotic process GO:0006915 116 0.092
organic acid metabolic process GO:0006082 31 0.091
negative regulation of signaling GO:0023057 96 0.091
Human Zebrafish Rat Worm Fly
terpenoid metabolic process GO:0006721 15 0.090
ear development GO:0043583 127 0.090
negative regulation of cellular biosynthetic process GO:0031327 55 0.090
ventricular system development GO:0021591 12 0.090
regulation of cellular biosynthetic process GO:0031326 245 0.090
axis specification GO:0009798 43 0.089
Zebrafish Rat Worm
fertilization GO:0009566 3 0.089
myeloid cell differentiation GO:0030099 86 0.088
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.088
regulation of notch signaling pathway GO:0008593 16 0.087
photoreceptor cell differentiation GO:0046530 55 0.086
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.086
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.084
regulation of cellular ketone metabolic process GO:0010565 7 0.084
regulation of intracellular protein transport GO:0033157 3 0.084
Human
neural crest cell development GO:0014032 62 0.083
maintenance of location GO:0051235 4 0.083
neural crest cell differentiation GO:0014033 72 0.081
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.081
cell proliferation GO:0008283 80 0.081
Human Mouse Rat
neuron projection guidance GO:0097485 86 0.080
Worm
wound healing GO:0042060 90 0.080
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.079
Human Zebrafish Rat
germ cell migration GO:0008354 8 0.079
regulation of cell fate commitment GO:0010453 22 0.079
Worm
convergent extension involved in gastrulation GO:0060027 71 0.079
nuclear transport GO:0051169 4 0.079
Human
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.078
cellular ketone metabolic process GO:0042180 11 0.078
cellular component assembly GO:0022607 170 0.078
mononuclear cell proliferation GO:0032943 1 0.078
regulation of wnt signaling pathway GO:0030111 53 0.077
Human Zebrafish Mouse Rat Worm Fly
vasculature development GO:0001944 278 0.077
forebrain generation of neurons GO:0021872 14 0.077
Zebrafish
negative regulation of stem cell differentiation GO:2000737 2 0.076
positive regulation of signal transduction GO:0009967 56 0.076
Zebrafish
cell recognition GO:0008037 19 0.075
Worm
immune response GO:0006955 28 0.074
regulation of stem cell differentiation GO:2000736 4 0.074
Human
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.073
Fly
gland morphogenesis GO:0022612 13 0.073
regulation of cytoplasmic transport GO:1903649 4 0.072
Human
regulation of cell proliferation involved in tissue homeostasis GO:0060784 2 0.072
mesodermal cell differentiation GO:0048333 21 0.072
striated muscle cell development GO:0055002 108 0.072
striated muscle cell differentiation GO:0051146 129 0.072
negative chemotaxis GO:0050919 1 0.072
axon guidance GO:0007411 86 0.071
Worm
striated muscle tissue development GO:0014706 110 0.071
cell morphogenesis GO:0000902 289 0.071
Human Worm
positive regulation of cell proliferation GO:0008284 15 0.070
neural tube formation GO:0001841 16 0.070
optic placode formation GO:0001743 4 0.070
Zebrafish
positive regulation of catalytic activity GO:0043085 25 0.070
Zebrafish Rat
regulation of cellular protein metabolic process GO:0032268 52 0.069
Human Zebrafish Rat
regulation of epithelial cell proliferation GO:0050678 3 0.069
regulation of protein localization to nucleus GO:1900180 2 0.069
Human
regulation of binding GO:0051098 3 0.069
positive regulation of cell differentiation GO:0045597 30 0.068
Human
regulation of nucleocytoplasmic transport GO:0046822 2 0.068
Human
ear morphogenesis GO:0042471 64 0.068
regulation of transferase activity GO:0051338 16 0.067
Zebrafish Rat
stem cell differentiation GO:0048863 117 0.067
Human Fly
epithelial structure maintenance GO:0010669 8 0.067
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.067
forebrain anterior posterior pattern specification GO:0021797 3 0.067
Zebrafish
negative regulation of biosynthetic process GO:0009890 55 0.067
positive regulation of protein deacetylation GO:0090312 1 0.066
enzyme linked receptor protein signaling pathway GO:0007167 106 0.066
bone development GO:0060348 14 0.066
Mouse
positive regulation of cell cycle GO:0045787 3 0.066
regulation of protein metabolic process GO:0051246 56 0.065
Human Zebrafish Rat
positive regulation of cell activation GO:0050867 1 0.065
regulation of developmental growth GO:0048638 38 0.065
Worm
regulation of reproductive process GO:2000241 4 0.065
muscle cell development GO:0055001 115 0.064
Zebrafish
epithelial cell differentiation GO:0030855 116 0.064
cellular response to retinoic acid GO:0071300 1 0.064
regulation of embryonic development GO:0045995 47 0.063
regulation of protein targeting GO:1903533 2 0.063
Human
forebrain cell migration GO:0021885 1 0.063
cardiocyte differentiation GO:0035051 44 0.063
positive regulation of cellular metabolic process GO:0031325 94 0.063
Human Zebrafish Rat
regulation of skeletal muscle tissue development GO:0048641 4 0.063
regulation of histone deacetylation GO:0031063 2 0.063
positive regulation of macromolecule metabolic process GO:0010604 93 0.062
Human Zebrafish Rat
single organism nuclear import GO:1902593 3 0.060
Human
retinoic acid metabolic process GO:0042573 9 0.060
regulation of defense response GO:0031347 14 0.060
locomotion GO:0040011 313 0.059
Worm
negative regulation of cell migration GO:0030336 17 0.059
exocrine system development GO:0035272 28 0.059
positive regulation of notch signaling pathway GO:0045747 3 0.059
adult behavior GO:0030534 2 0.059
stem cell maintenance GO:0019827 4 0.059
Fly
angiogenesis GO:0001525 158 0.058
regulation of catalytic activity GO:0050790 55 0.058
Zebrafish Rat
response to vitamin GO:0033273 3 0.057
cell projection assembly GO:0030031 64 0.057
chromatin modification GO:0016568 21 0.057
negative regulation of myeloid cell differentiation GO:0045638 1 0.056
positive regulation of apoptotic process GO:0043065 29 0.056
lymphocyte proliferation GO:0046651 1 0.056
heparan sulfate proteoglycan metabolic process GO:0030201 6 0.055
cell proliferation in hindbrain GO:0021534 4 0.055
stem cell division GO:0017145 1 0.055
regulation of cell death GO:0010941 103 0.055
Human
regeneration GO:0031099 91 0.054
Zebrafish
hypothalamus development GO:0021854 14 0.054
cell fate commitment GO:0045165 99 0.054
Zebrafish Worm
regulation of response to stress GO:0080134 36 0.054
Human Zebrafish
female sex differentiation GO:0046660 4 0.054
glial cell migration GO:0008347 3 0.053
response to stress GO:0006950 263 0.052
Human Zebrafish
posttranscriptional regulation of gene expression GO:0010608 14 0.052
Human
leukocyte proliferation GO:0070661 1 0.051
regulation of programmed cell death GO:0043067 101 0.050
outflow tract morphogenesis GO:0003151 1 0.050
cellular aromatic compound metabolic process GO:0006725 295 0.049
Human
cell cycle process GO:0022402 53 0.049
Human Mouse Worm
cellular lipid metabolic process GO:0044255 36 0.049
retina morphogenesis in camera type eye GO:0060042 79 0.049
positive regulation of programmed cell death GO:0043068 29 0.049
positive regulation of nucleic acid templated transcription GO:1903508 57 0.049
inner ear development GO:0048839 126 0.049
positive regulation of gliogenesis GO:0014015 2 0.048
developmental process involved in reproduction GO:0003006 27 0.048
Worm Fly
positive regulation of transport GO:0051050 2 0.048
regulation of mesenchymal cell proliferation GO:0010464 1 0.047
embryonic skeletal system development GO:0048706 97 0.047
cilium assembly GO:0042384 58 0.047
positive regulation of neurogenesis GO:0050769 24 0.047
cell cycle GO:0007049 93 0.047
Human Mouse Worm
mesenchymal cell development GO:0014031 78 0.046
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.046
embryonic camera type eye morphogenesis GO:0048596 19 0.046
rostrocaudal neural tube patterning GO:0021903 29 0.046
regulation of dna replication GO:0006275 3 0.046
regulation of kinase activity GO:0043549 15 0.046
Zebrafish Rat
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.046
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.045
leukocyte activation GO:0045321 12 0.045
phagocytosis engulfment GO:0006911 1 0.045
myotube differentiation GO:0014902 45 0.045
regulation of cell migration GO:0030334 40 0.044
compound eye development GO:0048749 2 0.044
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.044
Zebrafish
multi organism reproductive process GO:0044703 36 0.044
Worm Fly
diterpenoid metabolic process GO:0016101 15 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.044
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.044
negative regulation of gene expression GO:0010629 65 0.044
protein complex subunit organization GO:0071822 46 0.044
Worm
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.043
negative regulation of multicellular organismal process GO:0051241 69 0.043
Mouse Rat Worm
development of primary female sexual characteristics GO:0046545 4 0.043
mesenchymal cell proliferation GO:0010463 1 0.043
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.043
growth GO:0040007 174 0.043
Zebrafish Worm
positive regulation of multicellular organismal process GO:0051240 52 0.043
Human Worm
cytoskeleton organization GO:0007010 96 0.042
Worm
reproduction GO:0000003 40 0.042
Worm Fly
positive regulation of immune system process GO:0002684 17 0.042
cell part morphogenesis GO:0032990 246 0.042
Worm
response to oxygen containing compound GO:1901700 55 0.041
skin development GO:0043588 54 0.041
regulation of cell morphogenesis GO:0022604 42 0.040
Human
glial cell differentiation GO:0010001 42 0.040
lateral inhibition GO:0046331 1 0.039
erk1 and erk2 cascade GO:0070371 4 0.039
epithelial to mesenchymal transition GO:0001837 21 0.039
Human
positive regulation of innate immune response GO:0045089 8 0.039
cell migration involved in heart formation GO:0060974 10 0.039
female gonad development GO:0008585 4 0.039
response to external biotic stimulus GO:0043207 97 0.039
macromolecule deacylation GO:0098732 3 0.039
neural tube patterning GO:0021532 33 0.039
heart jogging GO:0003146 40 0.039
single organism localization GO:1902578 225 0.039
Human Fly
optic placode formation involved in camera type eye formation GO:0046619 3 0.039
negative regulation of axon guidance GO:1902668 1 0.039
morphogenesis of a branching epithelium GO:0061138 16 0.038
anterior posterior axon guidance GO:0033564 5 0.038
posterior lateral line neuromast development GO:0048919 20 0.038
positive regulation of biosynthetic process GO:0009891 68 0.038
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.038
positive regulation of cell death GO:0010942 29 0.038
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.037
Zebrafish
positive regulation of reproductive process GO:2000243 2 0.037
renal tubule morphogenesis GO:0061333 1 0.037
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.037
tube closure GO:0060606 1 0.037
negative regulation of rna metabolic process GO:0051253 48 0.037
positive regulation of cell development GO:0010720 25 0.036
Human
homeostatic process GO:0042592 142 0.036
system process GO:0003008 185 0.036
endoderm formation GO:0001706 29 0.036
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.036
negative regulation of protein transport GO:0051224 3 0.036
Human
skeletal muscle fiber development GO:0048741 35 0.036
regulation of smoothened signaling pathway GO:0008589 18 0.035
specification of axis polarity GO:0065001 4 0.035
negative regulation of locomotion GO:0040013 18 0.035
membrane invagination GO:0010324 1 0.035
spinal cord radial glial cell differentiation GO:0021531 2 0.035
renal system development GO:0072001 94 0.035
endocrine system development GO:0035270 65 0.035
collagen metabolic process GO:0032963 2 0.034
odontogenesis of dentin containing tooth GO:0042475 1 0.034
positive regulation of response to stimulus GO:0048584 80 0.034
Zebrafish
foregut morphogenesis GO:0007440 4 0.033
synaptic target recognition GO:0008039 1 0.033
macromolecular complex subunit organization GO:0043933 74 0.033
Worm

axin2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.466
bone disease DOID:0080001 0 0.157
musculoskeletal system disease DOID:17 0 0.157
connective tissue disease DOID:65 0 0.157
cancer DOID:162 0 0.144
Human
disease of cellular proliferation DOID:14566 0 0.144
Human
organ system cancer DOID:0050686 0 0.080
Human
bone development disease DOID:0080006 0 0.055
nervous system disease DOID:863 0 0.039
large intestine cancer DOID:5672 0 0.034
Human
gastrointestinal system cancer DOID:3119 0 0.034
Human
intestinal cancer DOID:10155 0 0.034
Human
colorectal cancer DOID:9256 0 0.034
Human