Danio rerio

25 known processes

bad

BCL2-antagonist of cell death

(Aliases: wu:fa96d04,wu:fa01b12)

bad biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.420
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.288
Mouse
larval development GO:0002164 2 0.258
regulation of metabolic process GO:0019222 359 0.250
Mouse
positive regulation of cell death GO:0010942 29 0.245
regulation of cell death GO:0010941 103 0.216
positive regulation of apoptotic process GO:0043065 29 0.201
membrane fusion GO:0061025 2 0.128
cell death GO:0008219 121 0.126
organelle fusion GO:0048284 3 0.117
transmembrane transport GO:0055085 120 0.116
regulation of mitochondrion organization GO:0010821 1 0.110
death GO:0016265 121 0.109
regulation of cysteine type endopeptidase activity GO:2000116 21 0.108
Mouse
regulation of programmed cell death GO:0043067 101 0.105
phosphorus metabolic process GO:0006793 109 0.098
Mouse
positive regulation of programmed cell death GO:0043068 29 0.097
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.095
Mouse
negative regulation of mitosis GO:0045839 3 0.092
apoptotic process GO:0006915 116 0.088
regulation of endopeptidase activity GO:0052548 23 0.085
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.084
Mouse
regulation of peptidase activity GO:0052547 23 0.080
Mouse
cellular response to external stimulus GO:0071496 2 0.079
positive regulation of cellular process GO:0048522 201 0.079
response to vitamin b3 GO:0033552 2 0.075
regulation of nucleotide catabolic process GO:0030811 2 0.075
regulation of apoptotic process GO:0042981 98 0.075
regulation of primary metabolic process GO:0080090 311 0.065
Mouse
negative regulation of nuclear division GO:0051784 3 0.064
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.063
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.063
fertilization GO:0009566 3 0.063
response to amphetamine GO:0001975 1 0.057
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.056
regulation of metal ion transport GO:0010959 4 0.054
regulation of biological quality GO:0065008 263 0.052
Mouse
single organism membrane fusion GO:0044801 2 0.048
small molecule metabolic process GO:0044281 77 0.047
Mouse
angiogenesis GO:0001525 158 0.047
response to nutrient GO:0007584 3 0.046
organonitrogen compound metabolic process GO:1901564 74 0.045
Mouse
negative regulation of catalytic activity GO:0043086 21 0.045
cellular response to oxygen levels GO:0071453 1 0.044
apoptotic process involved in development GO:1902742 2 0.044
chordate embryonic development GO:0043009 271 0.043
cellular amine metabolic process GO:0044106 2 0.043
regulation of cellular amine metabolic process GO:0033238 0 0.042
guanosine containing compound catabolic process GO:1901069 2 0.042
apoptotic process involved in morphogenesis GO:0060561 2 0.041
cellular response to hypoxia GO:0071456 1 0.041
negative regulation of macromolecule metabolic process GO:0010605 76 0.040
regulation of gtp catabolic process GO:0033124 2 0.040
maintenance of location GO:0051235 4 0.039
regulation of blood pressure GO:0008217 1 0.039
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.039
guanosine containing compound metabolic process GO:1901068 4 0.038
lipid catabolic process GO:0016042 4 0.037
amine metabolic process GO:0009308 2 0.037
positive regulation of peptidase activity GO:0010952 10 0.036
Mouse
multi organism cellular process GO:0044764 2 0.036
Mouse
positive regulation of gtpase activity GO:0043547 1 0.036
regionalization GO:0003002 274 0.035
lipid homeostasis GO:0055088 3 0.035
positive regulation of biological process GO:0048518 253 0.035
triglyceride homeostasis GO:0070328 2 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.034
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
calcium ion import GO:0070509 4 0.034
cell death in response to oxidative stress GO:0036473 2 0.034
cellular response to organic cyclic compound GO:0071407 38 0.034
zymogen activation GO:0031638 3 0.033
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.032
gas transport GO:0015669 3 0.032
regulation of cellular metabolic process GO:0031323 320 0.032
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.031
Mouse
mitochondrion organization GO:0007005 4 0.031
Mouse
negative regulation of gene expression GO:0010629 65 0.031
biosynthetic process GO:0009058 294 0.030
proteolysis GO:0006508 38 0.030
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.030
positive regulation of gtp catabolic process GO:0033126 1 0.030
lipid storage GO:0019915 1 0.029
killing of cells of other organism GO:0031640 1 0.029
Mouse
gtp catabolic process GO:0006184 2 0.029
positive regulation of cellular metabolic process GO:0031325 94 0.029
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.028
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.028
regulation of lipid catabolic process GO:0050994 2 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
endocrine system development GO:0035270 65 0.027
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.027
positive regulation of transport GO:0051050 2 0.027
Mouse
oxoacid metabolic process GO:0043436 31 0.027
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.027
negative regulation of cell cycle GO:0045786 14 0.026
response to steroid hormone GO:0048545 35 0.026
response to lipid GO:0033993 60 0.026
Mouse
organic substance biosynthetic process GO:1901576 289 0.026
programmed cell death GO:0012501 119 0.026
gtp metabolic process GO:0046039 4 0.026
establishment of localization GO:0051234 244 0.025
Mouse
regulation of calcium ion transport GO:0051924 2 0.025
acylglycerol homeostasis GO:0055090 2 0.025
sensory perception of chemical stimulus GO:0007606 3 0.025
reactive oxygen species biosynthetic process GO:1903409 1 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
peptidyl serine phosphorylation GO:0018105 1 0.025
heterocycle metabolic process GO:0046483 290 0.025
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.024
regulation of catalytic activity GO:0050790 55 0.024
Mouse
transport GO:0006810 220 0.024
Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
Mouse
negative regulation of metabolic process GO:0009892 86 0.024
developmental programmed cell death GO:0010623 4 0.024
cellular response to chemical stimulus GO:0070887 157 0.023
cellular aldehyde metabolic process GO:0006081 4 0.023
response to hexose GO:0009746 3 0.023
Mouse
cation transport GO:0006812 81 0.023
negative regulation of kinase activity GO:0033673 4 0.023
homeostatic process GO:0042592 142 0.023
Mouse
cellular response to decreased oxygen levels GO:0036294 1 0.023
reactive oxygen species metabolic process GO:0072593 6 0.023
cell migration GO:0016477 237 0.023
negative regulation of proteolysis GO:0045861 10 0.022
aging GO:0007568 2 0.022
carboxylic acid metabolic process GO:0019752 22 0.021
regulation of ph GO:0006885 3 0.021
stem cell differentiation GO:0048863 117 0.021
protein localization to nucleus GO:0034504 3 0.021
regulation of tube size GO:0035150 2 0.021
regulation of phosphate metabolic process GO:0019220 43 0.021
Mouse
nitric oxide biosynthetic process GO:0006809 2 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
regulation of organ growth GO:0046620 3 0.020
epithelium migration GO:0090132 25 0.020
cellular lipid metabolic process GO:0044255 36 0.020
single organism metabolic process GO:0044710 217 0.020
Mouse
synaptic vesicle localization GO:0097479 1 0.020
stem cell development GO:0048864 82 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.019
negative regulation of cell communication GO:0010648 96 0.019
locomotion GO:0040011 313 0.019
stem cell maintenance GO:0019827 4 0.019
cellular biogenic amine metabolic process GO:0006576 2 0.019
negative regulation of tor signaling GO:0032007 2 0.019
negative regulation of cellular metabolic process GO:0031324 77 0.019
response to uv GO:0009411 3 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
Mouse
regulation of synaptic plasticity GO:0048167 1 0.019
negative regulation of programmed cell death GO:0043069 58 0.018
Mouse
hindbrain formation GO:0021576 3 0.018
regulation of gtpase activity GO:0043087 2 0.018
chemical homeostasis GO:0048878 49 0.018
Mouse
peptidyl serine modification GO:0018209 2 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
positive regulation of catabolic process GO:0009896 4 0.018
nucleobase containing small molecule metabolic process GO:0055086 32 0.018
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.018
Mouse
cell proliferation GO:0008283 80 0.018
Mouse
regulation of protein catabolic process GO:0042176 1 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
Mouse
heterocycle biosynthetic process GO:0018130 215 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
tissue remodeling GO:0048771 4 0.017
blood vessel development GO:0001568 246 0.017
regulation of hormone secretion GO:0046883 2 0.017
Mouse
synaptic vesicle transport GO:0048489 1 0.017
gastrulation GO:0007369 208 0.017
response to oxygen containing compound GO:1901700 55 0.017
Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.017
Mouse
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.017
Mouse
germ line stem cell division GO:0042078 1 0.017
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.017
negative regulation of cellular process GO:0048523 283 0.017
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
Mouse
regulation of developmental process GO:0050793 247 0.016
Mouse
nuclear import GO:0051170 3 0.016
cellular biosynthetic process GO:0044249 286 0.016
cell projection organization GO:0030030 284 0.016
response to vitamin GO:0033273 3 0.016
response to hormone GO:0009725 48 0.016
cytokinesis GO:0000910 3 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
signal transduction GO:0007165 455 0.016
Mouse
embryonic appendage morphogenesis GO:0035113 30 0.016
cation homeostasis GO:0055080 33 0.015
disruption of cells of other organism GO:0044364 1 0.015
Mouse
organelle organization GO:0006996 227 0.015
Mouse
fat soluble vitamin biosynthetic process GO:0042362 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
single organism biosynthetic process GO:0044711 71 0.015
organic acid metabolic process GO:0006082 31 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
cardiac muscle cell differentiation GO:0055007 30 0.015
golgi vesicle transport GO:0048193 3 0.015
negative regulation of protein maturation GO:1903318 10 0.015
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.015
Mouse
nucleocytoplasmic transport GO:0006913 4 0.015
response to metal ion GO:0010038 34 0.015
cellular ketone metabolic process GO:0042180 11 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.014
viral process GO:0016032 1 0.014
Mouse
response to inorganic substance GO:0010035 38 0.014
regulation of blood vessel size GO:0050880 2 0.014
response to alkaloid GO:0043279 2 0.014
diterpenoid metabolic process GO:0016101 15 0.014
cellular response to radiation GO:0071478 4 0.014
segmentation GO:0035282 97 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
negative regulation of protein metabolic process GO:0051248 16 0.014
cellular response to organic substance GO:0071310 105 0.014
autophagy GO:0006914 4 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
response to cadmium ion GO:0046686 14 0.013
negative regulation of catabolic process GO:0009895 3 0.013
positive regulation of cell cycle GO:0045787 3 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
spindle assembly GO:0051225 2 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
Mouse
regulation of gene expression GO:0010468 265 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
sensory organ development GO:0007423 393 0.013
response to amine GO:0014075 1 0.013
regulation of autophagy GO:0010506 3 0.013
tube formation GO:0035148 25 0.013
digestive system development GO:0055123 289 0.013
regulation of sodium ion transport GO:0002028 2 0.012
regulation of cytokine production GO:0001817 3 0.012
vestibular receptor cell differentiation GO:0060114 3 0.012
negative regulation of dna replication GO:0008156 2 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of synapse organization GO:0050807 3 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
Mouse
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.012
protein import GO:0017038 3 0.012
sodium ion import GO:0097369 3 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of molecular function GO:0065009 70 0.012
Mouse
negative regulation of cellular protein metabolic process GO:0032269 16 0.012
thyroid gland development GO:0030878 12 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
positive regulation of neuron death GO:1901216 1 0.012
protein metabolic process GO:0019538 183 0.012
Mouse
alcohol biosynthetic process GO:0046165 2 0.012
muscle hypertrophy GO:0014896 2 0.012
cellular response to nutrient levels GO:0031669 2 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
phosphorylation GO:0016310 69 0.011
Mouse
digestive tract development GO:0048565 265 0.011
modification of morphology or physiology of other organism GO:0035821 4 0.011
Mouse
positive regulation of catalytic activity GO:0043085 25 0.011
Mouse
regulation of oxidative stress induced cell death GO:1903201 2 0.011
epithelial cell differentiation GO:0030855 116 0.011
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
lymphocyte proliferation GO:0046651 1 0.011
small molecule catabolic process GO:0044282 3 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
nitric oxide metabolic process GO:0046209 2 0.011
cellular response to lipid GO:0071396 39 0.011
Mouse
cofactor metabolic process GO:0051186 15 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
mrna 3 end processing GO:0031124 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
single organism transport GO:0044765 206 0.011
Mouse
negative regulation of peptidase activity GO:0010466 10 0.011
mitotic cytokinesis GO:0000281 3 0.011
germ line stem cell maintenance GO:0030718 2 0.011
response to glucose GO:0009749 3 0.011
Mouse
gland development GO:0048732 143 0.011
localization of cell GO:0051674 244 0.011
membrane lipid metabolic process GO:0006643 10 0.011
morphogenesis of an epithelium GO:0002009 333 0.010
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.010
cellular lipid catabolic process GO:0044242 3 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
response to stress GO:0006950 263 0.010
Mouse
adult behavior GO:0030534 2 0.010
brain development GO:0007420 293 0.010
lipid metabolic process GO:0006629 52 0.010
cellular response to starvation GO:0009267 1 0.010
rhombomere 6 development GO:0021572 4 0.010
gene silencing by mirna GO:0035195 3 0.010
negative regulation of cell death GO:0060548 60 0.010
Mouse
cellular response to stress GO:0033554 62 0.010
Mouse
regulation of reproductive process GO:2000241 4 0.010

bad disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.014
endocrine system disease DOID:28 0 0.014
cardiovascular system disease DOID:1287 0 0.011