Danio rerio

86 known processes

bbs7

Bardet-Biedl syndrome 7

(Aliases: id:ibd5048,zgc:153772)

bbs7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nonmotile primary cilium assembly GO:0035058 2 0.781
Worm
cilium morphogenesis GO:0060271 85 0.607
cilium organization GO:0044782 71 0.491
cilium assembly GO:0042384 58 0.427
cell projection assembly GO:0030031 64 0.357
cellular component assembly involved in morphogenesis GO:0010927 107 0.348
microtubule based movement GO:0007018 33 0.230
Worm
digestive system development GO:0055123 289 0.201
cellular component morphogenesis GO:0032989 336 0.190
cell part morphogenesis GO:0032990 246 0.188
signal transduction GO:0007165 455 0.187
locomotion GO:0040011 313 0.171
Worm
negative regulation of cellular process GO:0048523 283 0.146
organelle assembly GO:0070925 110 0.144
regulation of response to stimulus GO:0048583 269 0.139
brain development GO:0007420 293 0.136
central nervous system development GO:0007417 387 0.125
tube morphogenesis GO:0035239 349 0.120
determination of left right symmetry GO:0007368 179 0.111
cell surface receptor signaling pathway GO:0007166 325 0.107
head development GO:0060322 303 0.106
response to chemical GO:0042221 320 0.105
Worm
skeletal system development GO:0001501 181 0.100
cell morphogenesis GO:0000902 289 0.099
sensory organ development GO:0007423 393 0.098
cell projection organization GO:0030030 284 0.096
generation of neurons GO:0048699 385 0.095
gastrulation GO:0007369 208 0.094
cell projection morphogenesis GO:0048858 244 0.091
embryonic organ morphogenesis GO:0048562 274 0.089
axoneme assembly GO:0035082 9 0.087
localization of cell GO:0051674 244 0.086
single organism organelle organization GO:1902589 199 0.084
cell motility GO:0048870 244 0.081
determination of bilateral symmetry GO:0009855 204 0.080
pigmentation GO:0043473 85 0.080
forebrain cell migration GO:0021885 1 0.076
neuron differentiation GO:0030182 353 0.076
regulation of signal transduction GO:0009966 225 0.075
embryonic organ development GO:0048568 381 0.074
cellular nitrogen compound metabolic process GO:0034641 290 0.073
regulation of epithelial cell proliferation GO:0050678 3 0.072
smooth muscle contraction GO:0006939 2 0.072
single organism transport GO:0044765 206 0.070
cellular component assembly GO:0022607 170 0.065
ameboidal type cell migration GO:0001667 143 0.064
heart development GO:0007507 313 0.064
regulation of gene expression GO:0010468 265 0.064
camera type eye development GO:0043010 222 0.063
transport GO:0006810 220 0.062
organelle organization GO:0006996 227 0.061
pronephros development GO:0048793 69 0.060
hematopoietic or lymphoid organ development GO:0048534 191 0.060
eye development GO:0001654 277 0.059
cellular component movement GO:0006928 335 0.058
Worm
positive regulation of secretion GO:0051047 1 0.058
regulation of metabolic process GO:0019222 359 0.055
response to external stimulus GO:0009605 264 0.055
Worm
larval development GO:0002164 2 0.054
regulation of blood vessel size GO:0050880 2 0.052
pronephros morphogenesis GO:0072114 14 0.050
cellular pigmentation GO:0033059 30 0.049
immune system process GO:0002376 241 0.049
smoothened signaling pathway GO:0007224 30 0.048
specification of symmetry GO:0009799 204 0.048
negative regulation of biological process GO:0048519 304 0.046
meiotic nuclear division GO:0007126 4 0.045
taxis GO:0042330 109 0.045
Worm
neuron development GO:0048666 262 0.044
atp catabolic process GO:0006200 4 0.043
retina morphogenesis in camera type eye GO:0060042 79 0.042
kupffer s vesicle development GO:0070121 50 0.042
embryonic heart tube development GO:0035050 133 0.042
kidney development GO:0001822 92 0.041
response to glucocorticoid GO:0051384 1 0.040
morphogenesis of an epithelium GO:0002009 333 0.040
positive regulation of secretion by cell GO:1903532 1 0.040
regulation of cell communication GO:0010646 232 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
urogenital system development GO:0001655 97 0.040
establishment of localization GO:0051234 244 0.039
positive regulation of transport GO:0051050 2 0.039
organic substance biosynthetic process GO:1901576 289 0.038
digestive tract development GO:0048565 265 0.037
chordate embryonic development GO:0043009 271 0.037
regulation of hormone secretion GO:0046883 2 0.037
cytoskeleton organization GO:0007010 96 0.037
gene expression GO:0010467 252 0.037
regulation of cytokine production GO:0001817 3 0.036
multicellular organism growth GO:0035264 4 0.035
cellular biosynthetic process GO:0044249 286 0.035
embryonic limb morphogenesis GO:0030326 2 0.035
regulation of signaling GO:0023051 235 0.034
biosynthetic process GO:0009058 294 0.034
chemosensory behavior GO:0007635 1 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.033
meiotic cell cycle process GO:1903046 3 0.033
establishment of localization in cell GO:0051649 77 0.033
cellular aromatic compound metabolic process GO:0006725 295 0.032
cellular component disassembly GO:0022411 1 0.032
regulation of protein transport GO:0051223 3 0.032
camera type eye morphogenesis GO:0048593 108 0.032
aging GO:0007568 2 0.032
regulation of blood pressure GO:0008217 1 0.031
intracellular signal transduction GO:0035556 85 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
hormone transport GO:0009914 2 0.031
cell migration GO:0016477 237 0.031
regulation of intracellular signal transduction GO:1902531 57 0.030
response to organic substance GO:0010033 153 0.030
centrosome organization GO:0051297 1 0.030
cellular component biogenesis GO:0044085 178 0.030
cellular response to external stimulus GO:0071496 2 0.030
renal system development GO:0072001 94 0.030
dorsal ventral pattern formation GO:0009953 125 0.030
nitrogen compound metabolic process GO:0006807 319 0.030
sensory organ morphogenesis GO:0090596 200 0.029
long chain fatty acid metabolic process GO:0001676 1 0.029
cognition GO:0050890 1 0.029
microtubule bundle formation GO:0001578 9 0.028
vasculature development GO:0001944 278 0.028
heart looping GO:0001947 94 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
microtubule based process GO:0007017 60 0.027
Worm
spermatid differentiation GO:0048515 2 0.027
heterocycle metabolic process GO:0046483 290 0.027
organelle localization GO:0051640 49 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
system process GO:0003008 185 0.027
regulation of binding GO:0051098 3 0.027
oxoacid metabolic process GO:0043436 31 0.026
cellular localization GO:0051641 97 0.025
cilium movement GO:0003341 26 0.025
single organism cellular localization GO:1902580 46 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
response to ketone GO:1901654 1 0.025
establishment of organelle localization GO:0051656 45 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
stem cell proliferation GO:0072089 4 0.025
cell proliferation GO:0008283 80 0.024
regulation of organelle assembly GO:1902115 4 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of endocrine process GO:0044060 2 0.024
photoreceptor cell outer segment organization GO:0035845 9 0.024
establishment of vesicle localization GO:0051650 24 0.024
negative regulation of signal transduction GO:0009968 94 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
nucleic acid metabolic process GO:0090304 244 0.024
digestive tract morphogenesis GO:0048546 231 0.023
eye morphogenesis GO:0048592 144 0.023
regulation of response to nutrient levels GO:0032107 1 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.023
mitotic dna integrity checkpoint GO:0044774 4 0.023
spindle assembly GO:0051225 2 0.022
skeletal system morphogenesis GO:0048705 102 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
cellular protein metabolic process GO:0044267 129 0.021
photoreceptor cell maintenance GO:0045494 11 0.021
connective tissue development GO:0061448 99 0.021
heart morphogenesis GO:0003007 156 0.021
positive regulation of cell cycle GO:0045787 3 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.021
forebrain development GO:0030900 96 0.021
single fertilization GO:0007338 3 0.021
cartilage development GO:0051216 96 0.021
regulation of cell projection assembly GO:0060491 4 0.021
mesoderm morphogenesis GO:0048332 51 0.021
single organism metabolic process GO:0044710 217 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
negative regulation of metabolic process GO:0009892 86 0.020
embryonic heart tube morphogenesis GO:0003143 108 0.020
retina development in camera type eye GO:0060041 146 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
spermatid development GO:0007286 2 0.020
hormone secretion GO:0046879 2 0.020
melanosome transport GO:0032402 19 0.020
appendage development GO:0048736 80 0.020
regulation of biosynthetic process GO:0009889 250 0.020
regulation of jak stat cascade GO:0046425 3 0.020
central nervous system neuron differentiation GO:0021953 74 0.020
response to drug GO:0042493 3 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
phosphorus metabolic process GO:0006793 109 0.019
positive regulation of jak stat cascade GO:0046427 2 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
regulation of rna metabolic process GO:0051252 224 0.019
apoptotic process GO:0006915 116 0.019
blood circulation GO:0008015 87 0.019
regulation of tube size GO:0035150 2 0.018
pigment granule localization GO:0051875 25 0.018
response to monosaccharide GO:0034284 3 0.018
circulatory system process GO:0003013 87 0.018
neurological system process GO:0050877 62 0.018
regulation of cell activation GO:0050865 1 0.018
olfactory bulb development GO:0021772 4 0.018
protein import into nucleus GO:0006606 3 0.018
autophagy GO:0006914 4 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
nuclear import GO:0051170 3 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
intraciliary transport GO:0042073 7 0.017
Worm
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
single organism nuclear import GO:1902593 3 0.017
protein metabolic process GO:0019538 183 0.017
macromolecule modification GO:0043412 111 0.017
rna biosynthetic process GO:0032774 181 0.017
retina homeostasis GO:0001895 12 0.017
pigment granule aggregation in cell center GO:0051877 8 0.017
muscle tissue development GO:0060537 110 0.017
cell cycle arrest GO:0007050 1 0.017
nucleic acid templated transcription GO:0097659 181 0.017
muscle organ development GO:0007517 101 0.017
negative regulation of signaling GO:0023057 96 0.017
cellular response to starvation GO:0009267 1 0.017
inner ear receptor cell fate commitment GO:0060120 4 0.017
startle response GO:0001964 4 0.017
regulation of circadian rhythm GO:0042752 4 0.017
stem cell division GO:0017145 1 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
negative regulation of kinase activity GO:0033673 4 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
regulation of developmental process GO:0050793 247 0.016
centrosome cycle GO:0007098 1 0.016
hemopoiesis GO:0030097 183 0.016
regulation of locomotion GO:0040012 55 0.016
protein dephosphorylation GO:0006470 3 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
amine metabolic process GO:0009308 2 0.016
negative regulation of cell communication GO:0010648 96 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
regulation of wnt signaling pathway GO:0030111 53 0.015
response to light stimulus GO:0009416 46 0.015
compound eye development GO:0048749 2 0.015
neuron projection development GO:0031175 180 0.015
regulation of cell differentiation GO:0045595 142 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
protein import GO:0017038 3 0.015
lateral inhibition GO:0046331 1 0.015
regulation of response to oxidative stress GO:1902882 2 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
protein complex disassembly GO:0043241 1 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
mesoderm development GO:0007498 88 0.014
regulation of protein targeting GO:1903533 2 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
regionalization GO:0003002 274 0.014
forebrain regionalization GO:0021871 4 0.014
response to hexose GO:0009746 3 0.014
response to carbohydrate GO:0009743 3 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
small molecule metabolic process GO:0044281 77 0.014
regulation of cell shape GO:0008360 1 0.014
secondary metabolic process GO:0019748 3 0.014
establishment of pigment granule localization GO:0051905 22 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
cellular amine metabolic process GO:0044106 2 0.014
rna metabolic process GO:0016070 219 0.014
transcription dna templated GO:0006351 181 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
cellular response to nutrient levels GO:0031669 2 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
response to corticosteroid GO:0031960 1 0.014
cardiac muscle tissue development GO:0048738 48 0.014
regulation of synapse assembly GO:0051963 3 0.014
protein targeting to nucleus GO:0044744 3 0.014
single organism localization GO:1902578 225 0.014
negative regulation of gene expression GO:0010629 65 0.014
regulation of protein complex assembly GO:0043254 3 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.013
organic acid metabolic process GO:0006082 31 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
endocrine process GO:0050886 2 0.013
meiotic spindle organization GO:0000212 1 0.013
neural retina development GO:0003407 49 0.013
cellular response to hormone stimulus GO:0032870 39 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
regulation of protein binding GO:0043393 3 0.013
auditory receptor cell fate commitment GO:0009912 4 0.013
peptide transport GO:0015833 1 0.013
protein secretion GO:0009306 1 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
cellular response to organic substance GO:0071310 105 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
nuclear transport GO:0051169 4 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of transcription dna templated GO:0006355 213 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
regulation of cell motility GO:2000145 46 0.013
fin development GO:0033333 77 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
phagocytosis GO:0006909 3 0.012
positive regulation of exocytosis GO:0045921 1 0.012
macromolecular complex disassembly GO:0032984 1 0.012
cellular ketone metabolic process GO:0042180 11 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
spinal cord development GO:0021510 46 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
behavior GO:0007610 74 0.012
positive regulation of cell activation GO:0050867 1 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
membrane lipid biosynthetic process GO:0046467 2 0.012
photoreceptor cell development GO:0042461 40 0.012
growth GO:0040007 174 0.012
cell cycle g2 m phase transition GO:0044839 4 0.012
lateral line development GO:0048882 66 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
protein localization to nucleus GO:0034504 3 0.012
sensory perception GO:0007600 39 0.012
outflow tract morphogenesis GO:0003151 1 0.012
regulation of synapse organization GO:0050807 3 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
regulation of muscle contraction GO:0006937 3 0.012
muscle contraction GO:0006936 18 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
regulation of cell death GO:0010941 103 0.011
oxidation reduction process GO:0055114 41 0.011
macroautophagy GO:0016236 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
mitotic cytokinesis GO:0000281 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
protein modification process GO:0036211 100 0.011
cellular response to stress GO:0033554 62 0.011
nephric duct development GO:0072176 13 0.011
pharyngeal muscle development GO:0043282 4 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
photoreceptor cell fate specification GO:0043704 1 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
microtubule based transport GO:0010970 10 0.011
Worm
positive regulation of blood circulation GO:1903524 2 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
lipid storage GO:0019915 1 0.011
nuclear migration GO:0007097 3 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
convergent extension GO:0060026 118 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
death GO:0016265 121 0.011
positive regulation of signal transduction GO:0009967 56 0.011
regulation of primary metabolic process GO:0080090 311 0.011
negative regulation of tor signaling GO:0032007 2 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
striated muscle cell development GO:0055002 108 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of localization GO:0032879 104 0.011
locomotor rhythm GO:0045475 3 0.011
negative chemotaxis GO:0050919 1 0.011
female sex differentiation GO:0046660 4 0.011
positive regulation of cellular process GO:0048522 201 0.010
fatty acid biosynthetic process GO:0006633 4 0.010
aflatoxin metabolic process GO:0046222 1 0.010
tube closure GO:0060606 1 0.010
response to uv GO:0009411 3 0.010
regulation of tor signaling GO:0032006 7 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
cytoskeleton dependent intracellular transport GO:0030705 10 0.010
Worm
synaptic target recognition GO:0008039 1 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
maintenance of location GO:0051235 4 0.010
leukocyte proliferation GO:0070661 1 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
central nervous system neuron development GO:0021954 29 0.010

bbs7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.015
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.014
nonsyndromic deafness DOID:0050563 0 0.014
auditory system disease DOID:2742 0 0.014