Danio rerio

5 known processes

bglap

bone gamma-carboxyglutamate (gla) protein

bglap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 181 0.933
chordate embryonic development GO:0043009 271 0.596
response to mechanical stimulus GO:0009612 24 0.353
skeletal system morphogenesis GO:0048705 102 0.326
bone development GO:0060348 14 0.320
regulation of transcription involved in cell fate commitment GO:0060850 1 0.225
sensory organ morphogenesis GO:0090596 200 0.220
regulation of response to stimulus GO:0048583 269 0.179
endochondral bone growth GO:0003416 2 0.163
single organism nuclear import GO:1902593 3 0.143
embryonic organ development GO:0048568 381 0.134
neuron differentiation GO:0030182 353 0.116
positive regulation of catabolic process GO:0009896 4 0.109
regulation of protein ubiquitination GO:0031396 3 0.108
protein import GO:0017038 3 0.103
nuclear import GO:0051170 3 0.101
regulation of multicellular organism growth GO:0040014 4 0.095
embryonic cranial skeleton morphogenesis GO:0048701 90 0.092
dicarboxylic acid transport GO:0006835 1 0.091
inner ear development GO:0048839 126 0.091
cellular protein catabolic process GO:0044257 4 0.091
regulation of neurogenesis GO:0050767 87 0.089
ear development GO:0043583 127 0.089
protein targeting to nucleus GO:0044744 3 0.085
larval development GO:0002164 2 0.079
embryonic organ morphogenesis GO:0048562 274 0.077
nucleocytoplasmic transport GO:0006913 4 0.075
epithelial cell morphogenesis GO:0003382 2 0.075
positive regulation of transport GO:0051050 2 0.072
development of primary female sexual characteristics GO:0046545 4 0.071
response to wounding GO:0009611 116 0.070
inner ear morphogenesis GO:0042472 63 0.066
embryonic skeletal system development GO:0048706 97 0.063
bone morphogenesis GO:0060349 11 0.058
pronephros development GO:0048793 69 0.058
signal transduction in absence of ligand GO:0038034 1 0.057
eye development GO:0001654 277 0.057
multicellular organism growth GO:0035264 4 0.055
regulation of cell communication GO:0010646 232 0.055
morphogenesis of an epithelium GO:0002009 333 0.055
camera type eye development GO:0043010 222 0.054
regulation of signal transduction GO:0009966 225 0.052
sensory organ development GO:0007423 393 0.051
extrinsic apoptotic signaling pathway GO:0097191 3 0.050
ear morphogenesis GO:0042471 64 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.046
oligodendrocyte differentiation GO:0048709 23 0.046
regulation of nervous system development GO:0051960 90 0.045
growth plate cartilage morphogenesis GO:0003422 1 0.045
cellular component morphogenesis GO:0032989 336 0.044
ubiquitin dependent protein catabolic process GO:0006511 3 0.044
rho protein signal transduction GO:0007266 5 0.044
hemopoiesis GO:0030097 183 0.042
rna biosynthetic process GO:0032774 181 0.041
modification dependent protein catabolic process GO:0019941 3 0.041
protein import into nucleus GO:0006606 3 0.040
single organism cellular localization GO:1902580 46 0.039
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.039
regulation of protein localization to nucleus GO:1900180 2 0.039
growth plate cartilage development GO:0003417 2 0.038
central nervous system development GO:0007417 387 0.038
heart development GO:0007507 313 0.037
generation of neurons GO:0048699 385 0.036
specification of symmetry GO:0009799 204 0.036
cellular response to chemical stimulus GO:0070887 157 0.035
regulation of cell activation GO:0050865 1 0.035
muscle organ development GO:0007517 101 0.035
regulation of rna metabolic process GO:0051252 224 0.034
regulation of multicellular organismal development GO:2000026 223 0.034
hormone transport GO:0009914 2 0.033
pancreas development GO:0031016 84 0.033
maintenance of location GO:0051235 4 0.032
positive regulation of cell adhesion GO:0045785 1 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
cell proliferation GO:0008283 80 0.031
periodic partitioning GO:0007365 1 0.031
kidney development GO:0001822 92 0.031
urogenital system development GO:0001655 97 0.031
nucleic acid templated transcription GO:0097659 181 0.031
regulation of protein targeting GO:1903533 2 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.030
positive regulation of lipid metabolic process GO:0045834 1 0.029
response to monosaccharide GO:0034284 3 0.029
regulation of wound healing GO:0061041 2 0.029
superoxide metabolic process GO:0006801 2 0.028
regulation of endocrine process GO:0044060 2 0.028
renal system development GO:0072001 94 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
cell junction maintenance GO:0034331 2 0.027
eye photoreceptor cell differentiation GO:0001754 45 0.027
positive regulation of translation GO:0045727 1 0.026
cell substrate adhesion GO:0031589 4 0.026
chondrocyte development GO:0002063 4 0.026
inner ear receptor cell fate commitment GO:0060120 4 0.026
detection of stimulus GO:0051606 29 0.026
connective tissue development GO:0061448 99 0.026
regulation of endothelial cell proliferation GO:0001936 1 0.026
response to carbohydrate GO:0009743 3 0.026
determination of bilateral symmetry GO:0009855 204 0.025
immune system development GO:0002520 191 0.025
steroid hormone secretion GO:0035929 1 0.025
nuclear transport GO:0051169 4 0.024
notochord development GO:0030903 54 0.024
developmental growth involved in morphogenesis GO:0060560 86 0.024
pectoral fin development GO:0033339 50 0.024
eye morphogenesis GO:0048592 144 0.024
localization of cell GO:0051674 244 0.024
embryonic skeletal system morphogenesis GO:0048704 93 0.023
regulation of multicellular organismal metabolic process GO:0044246 2 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
regulation of cell development GO:0060284 100 0.022
foregut morphogenesis GO:0007440 4 0.022
positive regulation of cell activation GO:0050867 1 0.022
endocrine process GO:0050886 2 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
i kappab kinase nf kappab signaling GO:0007249 4 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
cell surface receptor signaling pathway GO:0007166 325 0.020
response to organic substance GO:0010033 153 0.020
regulation of p38mapk cascade GO:1900744 1 0.020
odontogenesis of dentin containing tooth GO:0042475 1 0.020
regulation of binding GO:0051098 3 0.020
regulation of mesenchymal cell proliferation GO:0010464 1 0.020
transcription dna templated GO:0006351 181 0.020
growth GO:0040007 174 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
regulation of developmental process GO:0050793 247 0.019
retina development in camera type eye GO:0060041 146 0.019
female sex differentiation GO:0046660 4 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
regulation of bone mineralization GO:0030500 2 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
regulation of lipid transport GO:0032368 4 0.019
regulation of developmental growth GO:0048638 38 0.018
regulation of cellular ph GO:0030641 1 0.018
muscle fiber development GO:0048747 52 0.018
regulation of filopodium assembly GO:0051489 2 0.018
neuron development GO:0048666 262 0.018
heterocycle metabolic process GO:0046483 290 0.018
neural nucleus development GO:0048857 15 0.018
regulation of cell proliferation GO:0042127 37 0.018
neuron fate specification GO:0048665 20 0.017
mononuclear cell proliferation GO:0032943 1 0.017
cell migration GO:0016477 237 0.017
cartilage development GO:0051216 96 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
death GO:0016265 121 0.017
regulation of transport GO:0051049 45 0.017
camera type eye morphogenesis GO:0048593 108 0.017
detection of stimulus involved in sensory perception GO:0050906 21 0.017
visual perception GO:0007601 17 0.016
sensory perception of mechanical stimulus GO:0050954 16 0.016
single organism localization GO:1902578 225 0.016
peptidyl serine modification GO:0018209 2 0.016
bone mineralization GO:0030282 9 0.016
negative regulation of biological process GO:0048519 304 0.016
mesenchymal cell proliferation GO:0010463 1 0.016
specification of organ identity GO:0010092 2 0.015
ovulation cycle GO:0042698 2 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
brain development GO:0007420 293 0.015
amino acid transport GO:0006865 2 0.015
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
regulation of signaling GO:0023051 235 0.015
phagocytosis engulfment GO:0006911 1 0.015
organelle fusion GO:0048284 3 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
response to glucose GO:0009749 3 0.014
regulation of biomineral tissue development GO:0070167 2 0.014
segment polarity determination GO:0007367 1 0.014
response to external stimulus GO:0009605 264 0.014
insulin like growth factor receptor signaling pathway GO:0048009 4 0.014
regulation of reproductive process GO:2000241 4 0.014
hindbrain development GO:0030902 91 0.014
regulation of myotube differentiation GO:0010830 2 0.014
hair cell differentiation GO:0035315 32 0.014
b cell mediated immunity GO:0019724 3 0.014
striated muscle tissue development GO:0014706 110 0.014
biomineral tissue development GO:0031214 13 0.014
cellular response to retinoic acid GO:0071300 1 0.014
digestive tract development GO:0048565 265 0.013
positive regulation of lipid catabolic process GO:0050996 1 0.013
regulation of cell differentiation GO:0045595 142 0.013
eye photoreceptor cell development GO:0042462 30 0.013
cellular response to organic substance GO:0071310 105 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
embryonic eye morphogenesis GO:0048048 30 0.013
sulfate transmembrane transport GO:1902358 2 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
hormone secretion GO:0046879 2 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
golgi vesicle transport GO:0048193 3 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 7 0.013
adult behavior GO:0030534 2 0.013
immune system process GO:0002376 241 0.013
protein modification process GO:0036211 100 0.013
mrna 3 end processing GO:0031124 2 0.012
endocrine hormone secretion GO:0060986 2 0.012
cartilage condensation GO:0001502 3 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
regulation of blood pressure GO:0008217 1 0.012
immunoglobulin production GO:0002377 1 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
negative regulation of leukocyte differentiation GO:1902106 1 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
cell cell signaling GO:0007267 52 0.012
negative regulation of growth rate GO:0045967 1 0.012
cellular macromolecule metabolic process GO:0044260 391 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
cellular response to growth factor stimulus GO:0071363 39 0.012
peptide transport GO:0015833 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
endodermal cell fate determination GO:0007493 2 0.011
protein localization to nucleus GO:0034504 3 0.011
regulation of protein transport GO:0051223 3 0.011
system process GO:0003008 185 0.011
negative regulation of reproductive process GO:2000242 3 0.011
sensory perception GO:0007600 39 0.011
determination of left right symmetry GO:0007368 179 0.011
epithelial tube formation GO:0072175 19 0.011
calcium ion import GO:0070509 4 0.011
regulation of glucose import GO:0046324 1 0.011
monocyte differentiation GO:0030224 2 0.011
regulation of oligodendrocyte differentiation GO:0048713 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
otic vesicle morphogenesis GO:0071600 34 0.011
anion transport GO:0006820 38 0.011
embryonic camera type eye morphogenesis GO:0048596 19 0.011
regulation of kinase activity GO:0043549 15 0.011
regulation of leukocyte differentiation GO:1902105 5 0.011
carboxylic acid transport GO:0046942 8 0.011
positive regulation of wound healing GO:0090303 1 0.011
neurotransmitter secretion GO:0007269 2 0.011
long chain fatty acid transport GO:0015909 1 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
localization within membrane GO:0051668 1 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
microtubule based process GO:0007017 60 0.010
bone remodeling GO:0046849 2 0.010
spermatid development GO:0007286 2 0.010
regulation of protein catabolic process GO:0042176 1 0.010
biosynthetic process GO:0009058 294 0.010
protein phosphorylation GO:0006468 47 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
positive regulation of biological process GO:0048518 253 0.010
cellular component movement GO:0006928 335 0.010
urea transport GO:0015840 11 0.010
smoothened signaling pathway GO:0007224 30 0.010
rna 3 end processing GO:0031123 2 0.010

bglap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.079
bone disease DOID:0080001 0 0.079
disease of anatomical entity DOID:7 0 0.079
musculoskeletal system disease DOID:17 0 0.079
connective tissue disease DOID:65 0 0.079
osteochondrodysplasia DOID:2256 0 0.031
osteogenesis imperfecta DOID:12347 0 0.016
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011
lysosomal storage disease DOID:3211 0 0.011