Danio rerio

0 known processes

blvrb

biliverdin reductase B (flavin reductase (NADPH))

(Aliases: cb1064,wu:fb73f01,zgc:91854)

blvrb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.195
erythrocyte homeostasis GO:0034101 55 0.175
larval development GO:0002164 2 0.129
organic substance biosynthetic process GO:1901576 289 0.120
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.108
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.094
hydrogen peroxide metabolic process GO:0042743 2 0.091
i kappab kinase nf kappab signaling GO:0007249 4 0.088
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.085
myeloid cell differentiation GO:0030099 86 0.081
hemopoiesis GO:0030097 183 0.081
homeostatic process GO:0042592 142 0.076
iron ion homeostasis GO:0055072 4 0.076
cellular response to external stimulus GO:0071496 2 0.073
response to xenobiotic stimulus GO:0009410 45 0.065
heterocycle biosynthetic process GO:0018130 215 0.062
Mouse
response to drug GO:0042493 3 0.060
single organism localization GO:1902578 225 0.059
response to stress GO:0006950 263 0.058
immune system development GO:0002520 191 0.058
biosynthetic process GO:0009058 294 0.058
Mouse
maintenance of location GO:0051235 4 0.058
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.053
defense response GO:0006952 47 0.053
porphyrin containing compound biosynthetic process GO:0006779 8 0.051
cellular response to reactive oxygen species GO:0034614 2 0.047
death GO:0016265 121 0.047
tetrapyrrole biosynthetic process GO:0033014 8 0.046
signal transduction GO:0007165 455 0.046
negative regulation of biological process GO:0048519 304 0.046
superoxide metabolic process GO:0006801 2 0.045
peptide transport GO:0015833 1 0.045
regulation of biological quality GO:0065008 263 0.044
establishment of localization GO:0051234 244 0.042
immune system process GO:0002376 241 0.042
response to chemical GO:0042221 320 0.037
cell death GO:0008219 121 0.037
regulation of primary metabolic process GO:0080090 311 0.037
Mouse
cofactor biosynthetic process GO:0051188 10 0.035
chloride transmembrane transport GO:1902476 4 0.035
cofactor metabolic process GO:0051186 15 0.034
nucleic acid templated transcription GO:0097659 181 0.034
Mouse
embryonic organ development GO:0048568 381 0.034
extrinsic apoptotic signaling pathway GO:0097191 3 0.033
bicarbonate transport GO:0015701 4 0.033
inorganic anion transport GO:0015698 25 0.033
macromolecule biosynthetic process GO:0009059 227 0.033
Mouse
programmed cell death GO:0012501 119 0.032
adult behavior GO:0030534 2 0.032
regulation of intracellular protein transport GO:0033157 3 0.032
organonitrogen compound metabolic process GO:1901564 74 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
response to abiotic stimulus GO:0009628 122 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
Mouse
multicellular organism growth GO:0035264 4 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.030
leukocyte proliferation GO:0070661 1 0.030
cellular transition metal ion homeostasis GO:0046916 3 0.029
positive regulation of transport GO:0051050 2 0.029
myeloid cell homeostasis GO:0002262 56 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
Mouse
regulation of carbohydrate metabolic process GO:0006109 4 0.029
regulation of multicellular organism growth GO:0040014 4 0.028
positive regulation of cellular process GO:0048522 201 0.028
Mouse
lipid storage GO:0019915 1 0.028
regulation of transcription dna templated GO:0006355 213 0.028
Mouse
rna biosynthetic process GO:0032774 181 0.028
Mouse
cellular response to xenobiotic stimulus GO:0071466 35 0.027
regulation of rna metabolic process GO:0051252 224 0.027
Mouse
cell cycle g1 s phase transition GO:0044843 1 0.027
mitochondrion organization GO:0007005 4 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.027
Mouse
positive regulation of wound healing GO:0090303 1 0.027
primitive erythrocyte differentiation GO:0060319 5 0.027
heme metabolic process GO:0042168 9 0.026
heterocycle metabolic process GO:0046483 290 0.026
Mouse
metal ion transport GO:0030001 58 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.025
positive regulation of catabolic process GO:0009896 4 0.025
erythrocyte maturation GO:0043249 8 0.025
transport GO:0006810 220 0.025
regulation of cell communication GO:0010646 232 0.025
cell projection organization GO:0030030 284 0.025
protein metabolic process GO:0019538 183 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.024
regulation of cell activation GO:0050865 1 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
Mouse
negative regulation of signal transduction GO:0009968 94 0.024
erythrocyte differentiation GO:0030218 54 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
cellular response to lipopolysaccharide GO:0071222 3 0.024
protein polymerization GO:0051258 4 0.024
cellular component morphogenesis GO:0032989 336 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
Mouse
transcription dna templated GO:0006351 181 0.023
Mouse
porphyrin containing compound metabolic process GO:0006778 10 0.023
homeostasis of number of cells GO:0048872 62 0.023
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.022
Mouse
regulation of blood pressure GO:0008217 1 0.022
synaptic vesicle recycling GO:0036465 1 0.022
regulation of blood vessel size GO:0050880 2 0.021
gland development GO:0048732 143 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
Mouse
alcohol biosynthetic process GO:0046165 2 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
regulation of wound healing GO:0061041 2 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
Mouse
ion transport GO:0006811 114 0.021
protein homooligomerization GO:0051260 3 0.021
autophagy GO:0006914 4 0.021
regulation of ph GO:0006885 3 0.021
cellular biosynthetic process GO:0044249 286 0.021
Mouse
regulation of establishment of protein localization GO:0070201 4 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
protein targeting to nucleus GO:0044744 3 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
single organism metabolic process GO:0044710 217 0.020
protein stabilization GO:0050821 2 0.020
regulation of metabolic process GO:0019222 359 0.020
Mouse
cellular response to molecule of bacterial origin GO:0071219 3 0.020
carbohydrate biosynthetic process GO:0016051 1 0.020
response to hydrogen peroxide GO:0042542 3 0.020
nucleic acid metabolic process GO:0090304 244 0.020
Mouse
aging GO:0007568 2 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
Mouse
single organism transport GO:0044765 206 0.020
cellular response to extracellular stimulus GO:0031668 2 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
phagocytosis GO:0006909 3 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
endosomal transport GO:0016197 2 0.019
regulation of apoptotic process GO:0042981 98 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
Mouse
cellular response to chemical stimulus GO:0070887 157 0.019
regulation of reactive oxygen species metabolic process GO:2000377 2 0.019
cellular amide metabolic process GO:0043603 4 0.019
negative regulation of cellular process GO:0048523 283 0.019
gtp catabolic process GO:0006184 2 0.019
cellular modified amino acid metabolic process GO:0006575 3 0.019
mononuclear cell proliferation GO:0032943 1 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
regulation of hemostasis GO:1900046 1 0.018
morphogenesis of an epithelium GO:0002009 333 0.017
regulation of cell death GO:0010941 103 0.017
regulation of cellular ph GO:0030641 1 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
monovalent inorganic cation transport GO:0015672 42 0.017
negative regulation of cell communication GO:0010648 96 0.017
tube morphogenesis GO:0035239 349 0.017
regulation of protein targeting GO:1903533 2 0.017
positive regulation of cell communication GO:0010647 56 0.017
cellular response to superoxide GO:0071451 2 0.017
gtp metabolic process GO:0046039 4 0.016
regulation of signaling GO:0023051 235 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
toxin transport GO:1901998 2 0.016
signal transduction in absence of ligand GO:0038034 1 0.016
rna metabolic process GO:0016070 219 0.016
Mouse
response to hexose GO:0009746 3 0.016
chemical homeostasis GO:0048878 49 0.016
negative regulation of leukocyte differentiation GO:1902106 1 0.016
protein import GO:0017038 3 0.015
hepaticobiliary system development GO:0061008 98 0.015
response to external stimulus GO:0009605 264 0.015
oxoacid metabolic process GO:0043436 31 0.015
nerve development GO:0021675 45 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
response to glucocorticoid GO:0051384 1 0.015
growth GO:0040007 174 0.015
removal of superoxide radicals GO:0019430 2 0.015
small molecule metabolic process GO:0044281 77 0.015
lymphocyte proliferation GO:0046651 1 0.015
single organism membrane fusion GO:0044801 2 0.015
establishment of localization in cell GO:0051649 77 0.015
hatching gland development GO:0048785 3 0.015
gene expression GO:0010467 252 0.015
Mouse
multicellular organismal macromolecule metabolic process GO:0044259 2 0.015
zymogen activation GO:0031638 3 0.015
nitric oxide biosynthetic process GO:0006809 2 0.015
cellular response to starvation GO:0009267 1 0.015
protein localization to plasma membrane GO:0072659 1 0.015
neuron development GO:0048666 262 0.015
tetrapyrrole metabolic process GO:0033013 10 0.015
cellular component movement GO:0006928 335 0.015
regulation of cell shape GO:0008360 1 0.014
regulation of protein transport GO:0051223 3 0.014
cellular ketone metabolic process GO:0042180 11 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
multi organism process GO:0051704 134 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
cellular protein metabolic process GO:0044267 129 0.014
membrane fusion GO:0061025 2 0.014
regulation of gene expression GO:0010468 265 0.014
Mouse
regulation of biomineral tissue development GO:0070167 2 0.014
regulation of carbohydrate biosynthetic process GO:0043255 1 0.014
regulation of developmental process GO:0050793 247 0.014
heme biosynthetic process GO:0006783 8 0.014
single organism nuclear import GO:1902593 3 0.014
cellular component disassembly GO:0022411 1 0.014
cellular amine metabolic process GO:0044106 2 0.014
vasculature development GO:0001944 278 0.013
protein import into nucleus GO:0006606 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
regulation of protein complex assembly GO:0043254 3 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
chloride transport GO:0006821 8 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
macromolecular complex disassembly GO:0032984 1 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
regulation of signal transduction GO:0009966 225 0.013
system process GO:0003008 185 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
cellular response to oxygen levels GO:0071453 1 0.013
protein localization to nucleus GO:0034504 3 0.013
meiotic nuclear division GO:0007126 4 0.013
positive regulation of cell cycle GO:0045787 3 0.013
regulation of neurotransmitter transport GO:0051588 1 0.012
neuron differentiation GO:0030182 353 0.012
regulation of hormone secretion GO:0046883 2 0.012
nucleic acid transport GO:0050657 2 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
protein secretion GO:0009306 1 0.012
regulation of intracellular ph GO:0051453 1 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
regulation of reproductive process GO:2000241 4 0.012
regulation of cytokine production GO:0001817 3 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
activation of mapk activity GO:0000187 3 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
organelle fusion GO:0048284 3 0.012
nuclear import GO:0051170 3 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of molecular function GO:0065009 70 0.012
response to alkaloid GO:0043279 2 0.012
organic substance transport GO:0071702 58 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
regulation of peptidase activity GO:0052547 23 0.012
response to corticosteroid GO:0031960 1 0.012
developmental growth GO:0048589 166 0.012
embryonic hemopoiesis GO:0035162 53 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
cell part morphogenesis GO:0032990 246 0.012
regulation of meiotic cell cycle GO:0051445 1 0.011
response to uv GO:0009411 3 0.011
intracellular signal transduction GO:0035556 85 0.011
protein complex disassembly GO:0043241 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
cellular protein catabolic process GO:0044257 4 0.011
establishment of rna localization GO:0051236 3 0.011
regulation of tube size GO:0035150 2 0.011
hormone transport GO:0009914 2 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
compound eye development GO:0048749 2 0.011
dipeptide transport GO:0042938 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
response to other organism GO:0051707 97 0.011
regulation of autophagy GO:0010506 3 0.011
ph reduction GO:0045851 1 0.011
organism emergence from protective structure GO:0071684 4 0.011
blood vessel development GO:0001568 246 0.011
negative chemotaxis GO:0050919 1 0.011
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
organelle organization GO:0006996 227 0.011
positive regulation of secretion GO:0051047 1 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
sodium ion transport GO:0006814 24 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
tissue remodeling GO:0048771 4 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
cranial nerve development GO:0021545 42 0.010
regulation of inflammatory response GO:0050727 2 0.010
organonitrogen compound biosynthetic process GO:1901566 47 0.010
digestive tract development GO:0048565 265 0.010
oligopeptide transport GO:0006857 1 0.010
negative regulation of kinase activity GO:0033673 4 0.010
regulation of lipid catabolic process GO:0050994 2 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
erythrocyte development GO:0048821 24 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
stem cell proliferation GO:0072089 4 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
Mouse
reactive oxygen species biosynthetic process GO:1903409 1 0.010
regulation of programmed cell death GO:0043067 101 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
cellular component assembly GO:0022607 170 0.010
multicellular organismal homeostasis GO:0048871 29 0.010

blvrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.033
disease of anatomical entity DOID:7 0 0.033
organ system cancer DOID:0050686 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
cancer DOID:162 0 0.028
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
musculoskeletal system disease DOID:17 0 0.012