Danio rerio

34 known processes

bmi1

B lymphoma Mo-MLV insertion region 1

(Aliases: wu:fb17g03,psc1,pcgf4,wu:fd18f06,bmi1a)

bmi1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 181 0.582
Human Mouse Fly
transcription dna templated GO:0006351 181 0.563
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.521
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.455
Human Mouse Fly
biosynthetic process GO:0009058 294 0.415
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.411
Human Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.386
Human Mouse Fly
regulation of rna metabolic process GO:0051252 224 0.342
Human Mouse Fly
heterocycle metabolic process GO:0046483 290 0.330
Human Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.321
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.319
Human Mouse Fly
cellular biosynthetic process GO:0044249 286 0.319
Human Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.317
Human Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.303
Human Mouse Fly
central nervous system development GO:0007417 387 0.286
regionalization GO:0003002 274 0.273
Mouse
regulation of metabolic process GO:0019222 359 0.268
Human Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.254
Human Mouse Fly
rna metabolic process GO:0016070 219 0.243
Human Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.234
Human Mouse Fly
regulation of transcription dna templated GO:0006355 213 0.217
Human Mouse Fly
digestive tract development GO:0048565 265 0.192
cellular nitrogen compound metabolic process GO:0034641 290 0.191
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.185
Human Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.179
Human Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.177
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.174
Human Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.170
Human Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.170
Human Mouse Fly
regulation of biosynthetic process GO:0009889 250 0.156
Human Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.155
Human Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.155
Human Mouse Fly
protein metabolic process GO:0019538 183 0.149
Human Mouse
rna biosynthetic process GO:0032774 181 0.148
Human Mouse Fly
response to chemical GO:0042221 320 0.144
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.132
Human Mouse
digestive system development GO:0055123 289 0.129
aromatic compound biosynthetic process GO:0019438 217 0.126
Human Mouse Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.121
Human
gene expression GO:0010467 252 0.117
Human Mouse Fly
tube morphogenesis GO:0035239 349 0.116
nucleobase containing compound metabolic process GO:0006139 274 0.113
Human Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.109
Human Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.100
Mouse
generation of neurons GO:0048699 385 0.100
Fly
immune system development GO:0002520 191 0.092
segmentation GO:0035282 97 0.090
digestive tract morphogenesis GO:0048546 231 0.088
transcription from rna polymerase ii promoter GO:0006366 80 0.086
Human Mouse
axon guidance GO:0007411 86 0.085
Fly
cell morphogenesis GO:0000902 289 0.084
Fly
skeletal system development GO:0001501 181 0.082
Mouse
response to external stimulus GO:0009605 264 0.081
Fly
hemopoiesis GO:0030097 183 0.081
regulation of binding GO:0051098 3 0.081
brain development GO:0007420 293 0.078
positive regulation of metabolic process GO:0009893 108 0.078
Human
macromolecule biosynthetic process GO:0009059 227 0.073
Human Mouse Fly
spindle assembly GO:0051225 2 0.070
multicellular organism growth GO:0035264 4 0.069
single organism organelle organization GO:1902589 199 0.069
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.069
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.068
Fly
cellular ketone metabolic process GO:0042180 11 0.066
organic acid metabolic process GO:0006082 31 0.064
axonogenesis GO:0007409 152 0.061
Fly
taxis GO:0042330 109 0.059
Fly
larval development GO:0002164 2 0.058
positive regulation of macromolecule metabolic process GO:0010604 93 0.058
Human
anterior posterior pattern specification GO:0009952 152 0.057
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.057
Human Mouse Fly
regulation of protein ubiquitination GO:0031396 3 0.057
Human
protein modification process GO:0036211 100 0.057
Human Mouse
erythrocyte homeostasis GO:0034101 55 0.056
chordate embryonic development GO:0043009 271 0.056
Mouse
cellular protein metabolic process GO:0044267 129 0.056
Human Mouse
chromatin modification GO:0016568 21 0.056
Mouse Fly
positive regulation of cellular metabolic process GO:0031325 94 0.056
Human
regulation of cellular metabolic process GO:0031323 320 0.055
Human Mouse Fly
positive regulation of biological process GO:0048518 253 0.055
Human Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.055
cellular component movement GO:0006928 335 0.054
regulation of establishment of protein localization GO:0070201 4 0.054
oxoacid metabolic process GO:0043436 31 0.053
regulation of epithelial cell proliferation GO:0050678 3 0.052
embryonic organ development GO:0048568 381 0.051
response to stress GO:0006950 263 0.049
regulation of nucleic acid templated transcription GO:1903506 213 0.049
Human Mouse Fly
carboxylic acid metabolic process GO:0019752 22 0.048
gastrulation GO:0007369 208 0.048
small molecule metabolic process GO:0044281 77 0.047
cell part morphogenesis GO:0032990 246 0.047
Fly
mitotic cell cycle GO:0000278 64 0.047
Fly
cell projection morphogenesis GO:0048858 244 0.046
Fly
neuron projection guidance GO:0097485 86 0.046
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.045
negative regulation of biological process GO:0048519 304 0.045
Human Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.044
Human Mouse Fly
response to abiotic stimulus GO:0009628 122 0.044
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.044
Human Mouse Fly
regulation of protein binding GO:0043393 3 0.043
developmental growth GO:0048589 166 0.043
negative regulation of signaling GO:0023057 96 0.042
Mouse
morphogenesis of an epithelium GO:0002009 333 0.042
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.041
Human Mouse Fly
cell cycle GO:0007049 93 0.041
Fly
single organism metabolic process GO:0044710 217 0.040
Mouse
protein localization to plasma membrane GO:0072659 1 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.040
Fly
cell projection organization GO:0030030 284 0.038
Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.037
Human Mouse Fly
erythrocyte differentiation GO:0030218 54 0.037
fertilization GO:0009566 3 0.037
negative regulation of response to stimulus GO:0048585 104 0.036
Mouse
protein modification by small protein conjugation or removal GO:0070647 14 0.036
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.035
regulation of biological quality GO:0065008 263 0.035
segment specification GO:0007379 12 0.034
myeloid cell differentiation GO:0030099 86 0.034
macromolecule modification GO:0043412 111 0.034
Human Mouse
cell cycle g1 s phase transition GO:0044843 1 0.034
neuron differentiation GO:0030182 353 0.034
Fly
lipid metabolic process GO:0006629 52 0.034
myeloid cell development GO:0061515 32 0.033
signal transduction GO:0007165 455 0.033
Mouse
maintenance of location GO:0051235 4 0.032
response to organic substance GO:0010033 153 0.032
regulation of signal transduction GO:0009966 225 0.032
Mouse
cellular amine metabolic process GO:0044106 2 0.032
erythrocyte development GO:0048821 24 0.031
negative regulation of cellular process GO:0048523 283 0.031
Human Mouse Fly
regulation of response to stimulus GO:0048583 269 0.031
Mouse
mrna metabolic process GO:0016071 20 0.030
lipid storage GO:0019915 1 0.030
embryonic skeletal system development GO:0048706 97 0.030
Mouse
response to oxygen containing compound GO:1901700 55 0.030
homeostatic process GO:0042592 142 0.029
cilium morphogenesis GO:0060271 85 0.029
aging GO:0007568 2 0.028
g1 s transition of mitotic cell cycle GO:0000082 1 0.028
locomotion GO:0040011 313 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.028
axon development GO:0061564 166 0.027
Fly
sensory organ morphogenesis GO:0090596 200 0.027
apoptotic process GO:0006915 116 0.026
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.026
positive regulation of catabolic process GO:0009896 4 0.026
regulation of protein transport GO:0051223 3 0.025
regulation of synapse organization GO:0050807 3 0.025
stem cell proliferation GO:0072089 4 0.025
skeletal system morphogenesis GO:0048705 102 0.025
Mouse
heart development GO:0007507 313 0.025
cell migration GO:0016477 237 0.025
positive regulation of cellular process GO:0048522 201 0.025
Human Mouse
cytoskeleton dependent cytokinesis GO:0061640 3 0.024
specification of symmetry GO:0009799 204 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.024
Human Mouse Fly
response to dexamethasone GO:0071548 1 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
immune system process GO:0002376 241 0.024
response to corticosteroid GO:0031960 1 0.024
fin development GO:0033333 77 0.023
response to ketone GO:1901654 1 0.023
cell morphogenesis involved in differentiation GO:0000904 195 0.023
Fly
phagocytosis GO:0006909 3 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
positive regulation of catalytic activity GO:0043085 25 0.023
Human
positive regulation of epithelial cell proliferation GO:0050679 1 0.023
mesoderm development GO:0007498 88 0.023
neuron projection development GO:0031175 180 0.023
Fly
positive regulation of jun kinase activity GO:0043507 2 0.022
skin development GO:0043588 54 0.022
autophagy GO:0006914 4 0.022
olfactory bulb development GO:0021772 4 0.022
regulation of molecular function GO:0065009 70 0.022
Human Mouse
neuron development GO:0048666 262 0.022
Fly
adult behavior GO:0030534 2 0.022
forebrain regionalization GO:0021871 4 0.022
mitochondrion organization GO:0007005 4 0.021
protein dephosphorylation GO:0006470 3 0.021
auditory receptor cell fate commitment GO:0009912 4 0.021
nuclear transport GO:0051169 4 0.021
cell proliferation GO:0008283 80 0.021
Human Mouse
regulation of stem cell proliferation GO:0072091 2 0.021
renal system development GO:0072001 94 0.020
cellular component assembly GO:0022607 170 0.020
positive regulation of nucleic acid templated transcription GO:1903508 57 0.020
cytokinesis GO:0000910 3 0.019
negative regulation of rna metabolic process GO:0051253 48 0.019
Human Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.019
determination of left right symmetry GO:0007368 179 0.019
sister chromatid cohesion GO:0007062 2 0.019
neuroblast proliferation GO:0007405 2 0.019
mucopolysaccharide metabolic process GO:1903510 2 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
amine metabolic process GO:0009308 2 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
determination of bilateral symmetry GO:0009855 204 0.018
negative regulation of metabolic process GO:0009892 86 0.018
Human Mouse Fly
meiotic nuclear division GO:0007126 4 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of signaling GO:0023051 235 0.017
Mouse
positive regulation of protein complex assembly GO:0031334 2 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
Human Mouse Fly
hindbrain development GO:0030902 91 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
response to uv GO:0009411 3 0.017
rna 3 end processing GO:0031123 2 0.017
single fertilization GO:0007338 3 0.017
somite development GO:0061053 96 0.017
cell migration involved in gastrulation GO:0042074 79 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.016
membrane invagination GO:0010324 1 0.016
positive regulation of cell cycle GO:0045787 3 0.016
developmental maturation GO:0021700 34 0.016
regulation of synapse assembly GO:0051963 3 0.016
positive regulation of transport GO:0051050 2 0.016
negative regulation of gene expression GO:0010629 65 0.016
Human Mouse Fly
positive regulation of transcription dna templated GO:0045893 57 0.016
somitogenesis GO:0001756 87 0.016
growth GO:0040007 174 0.016
eye development GO:0001654 277 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
response to hexose GO:0009746 3 0.016
endosomal transport GO:0016197 2 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
Human Mouse Fly
response to lipid GO:0033993 60 0.016
endothelial cell fate commitment GO:0060839 3 0.016
anterior posterior axis specification GO:0009948 20 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
Mouse
spindle localization GO:0051653 12 0.016
cellular response to external stimulus GO:0071496 2 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
Mouse Fly
single organism nuclear import GO:1902593 3 0.016
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of protein metabolic process GO:0051246 56 0.015
Human
negative regulation of multicellular organismal process GO:0051241 69 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
Mouse
programmed cell death GO:0012501 119 0.015
Mouse
protein localization to nucleus GO:0034504 3 0.015
protein acetylation GO:0006473 2 0.015
Mouse
response to glucocorticoid GO:0051384 1 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
cell cycle arrest GO:0007050 1 0.015
response to organic cyclic compound GO:0014070 51 0.015
positive regulation of molecular function GO:0044093 33 0.015
Human
stem cell division GO:0017145 1 0.014
Mouse
cellular protein modification process GO:0006464 100 0.014
Human Mouse
positive regulation of dna metabolic process GO:0051054 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
establishment of localization GO:0051234 244 0.014
organelle organization GO:0006996 227 0.014
Mouse Fly
embryonic organ morphogenesis GO:0048562 274 0.014
Mouse
regulation of myotube differentiation GO:0010830 2 0.014
regulation of protein targeting GO:1903533 2 0.014
response to monosaccharide GO:0034284 3 0.014
mitotic cell cycle embryonic GO:0045448 2 0.014
Fly
negative regulation of ras protein signal transduction GO:0046580 1 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
nuclear import GO:0051170 3 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
Human Mouse Fly
positive regulation of map kinase activity GO:0043406 3 0.013
olfactory lobe development GO:0021988 4 0.013
camera type eye development GO:0043010 222 0.013
spinal cord development GO:0021510 46 0.013
protein import GO:0017038 3 0.013
b cell differentiation GO:0030183 1 0.013
sensory organ development GO:0007423 393 0.013
synaptic target recognition GO:0008039 1 0.013
regulation of chromosome segregation GO:0051983 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
kidney development GO:0001822 92 0.013
protein acylation GO:0043543 3 0.013
Mouse
axis specification GO:0009798 43 0.013
establishment of organelle localization GO:0051656 45 0.013
transcription from rna polymerase iii promoter GO:0006383 1 0.013
wnt signaling pathway GO:0016055 80 0.013
protein ubiquitination GO:0016567 11 0.013
Human Mouse
mrna 3 end processing GO:0031124 2 0.013
metencephalon development GO:0022037 27 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.013
cellular response to organic substance GO:0071310 105 0.013
regulation of cell cycle GO:0051726 52 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
pectoral fin development GO:0033339 50 0.013
blood vessel development GO:0001568 246 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.012
Human
mitotic cytokinesis GO:0000281 3 0.012
negative chemotaxis GO:0050919 1 0.012
rna stabilization GO:0043489 4 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
cilium organization GO:0044782 71 0.012
neural tube patterning GO:0021532 33 0.012
Mouse
cellular response to nutrient levels GO:0031669 2 0.012
protein targeting to nucleus GO:0044744 3 0.012
hepaticobiliary system development GO:0061008 98 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
chromatin organization GO:0006325 22 0.012
Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular localization GO:0051641 97 0.012
spermatid differentiation GO:0048515 2 0.012
pharyngeal muscle development GO:0043282 4 0.012
dorsal ventral pattern formation GO:0009953 125 0.011
embryonic pattern specification GO:0009880 44 0.011
response to amino acid GO:0043200 2 0.011
system process GO:0003008 185 0.011
cell maturation GO:0048469 23 0.011
protein stabilization GO:0050821 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
activation of mapk activity GO:0000187 3 0.011
stem cell maintenance GO:0019827 4 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
gene silencing GO:0016458 4 0.011
Fly
negative regulation of cellular metabolic process GO:0031324 77 0.011
Human Mouse Fly
activation of jun kinase activity GO:0007257 2 0.011
liver development GO:0001889 96 0.011
multi organism process GO:0051704 134 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
cellular response to starvation GO:0009267 1 0.011
regulation of organ growth GO:0046620 3 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
mesoderm morphogenesis GO:0048332 51 0.011
lateral line development GO:0048882 66 0.011
cellular component disassembly GO:0022411 1 0.011
response to oxygen levels GO:0070482 25 0.011
cell proliferation in forebrain GO:0021846 3 0.011
pancreas development GO:0031016 84 0.011
epithelial cell differentiation GO:0030855 116 0.011
homeostasis of number of cells GO:0048872 62 0.011
spindle assembly involved in mitosis GO:0090307 1 0.010
negative regulation of developmental process GO:0051093 65 0.010
meiotic spindle organization GO:0000212 1 0.010
regulation of cell communication GO:0010646 232 0.010
Mouse
regulation of protein complex assembly GO:0043254 3 0.010
fin morphogenesis GO:0033334 53 0.010
regulation of cytokine production GO:0001817 3 0.010
cellular response to steroid hormone stimulus GO:0071383 31 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
forebrain cell migration GO:0021885 1 0.010
positive regulation of carbohydrate metabolic process GO:0045913 1 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
Mouse
positive regulation of chromosome organization GO:2001252 1 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
positive regulation of cellular protein metabolic process GO:0032270 22 0.010
Human
cortical cytoskeleton organization GO:0030865 1 0.010

bmi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.023
disease of anatomical entity DOID:7 0 0.023
eye and adnexa disease DOID:1492 0 0.023
nervous system disease DOID:863 0 0.023
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
eye disease DOID:5614 0 0.011